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Incidencia y factores de riesgo de hepatitis A en la provincia de Guadalajara
Incidence and risk factors for hepatitis a in the province of guadalajara (spain)
A. González Praetorius*,1, C. Rodríguez-Aviala, C. Fernándezb, M.T. Pérez Pomata1, C. Gimeno1, J. Bisquert1
1 Sección de Microbiología. Hospital General de Guadalajara. Universidad Complutense de Madrid. Madrid
a Departamento de Microbiología. Facultad de Medicina. Universidad Complutense de Madrid. Madrid
b Unidad de Investigación. Servicio de Medicina Preventiva. Hospital Clínico San Carlos. Madrid
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        "resumen" => "<span class="elsevierStyleSectionTitle">Fundamento</span><p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">El descenso de la prevalencia de hepatitis A en Espa&#241;a puede modificar las caracter&#237;sticas de esta infecci&#243;n por el aumento de la poblaci&#243;n adulta susceptible&#46; El objetivo de este estudio es conocer la incidencia de esta enfermedad&#44; as&#237; como las caracter&#237;sticas epidemiol&#243;gicas y las complicaciones de los pacientes diagnosticados en la provincia de Guadalajara entre 1991 y 1999&#46;</p> <span class="elsevierStyleSectionTitle">Pacientes y m&#233;todos</span><p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">El criterio de inclusi&#243;n fue la presencia de IgM espec&#237;fica junto con el aumento de la cifra de alanino aminotransferasa y&#47;o cl&#237;nica compatible con hepatitis aguda&#46;</p> <span class="elsevierStyleSectionTitle">Resultados</span><p id="spar0015" class="elsevierStyleSimplePara elsevierViewall">La incidencia media del estudio fue de 7&#44;13 casos&#47; 105 habitantes&#44; existiendo grandes diferencias entre los a&#241;os debido a la presencia de un brote&#46; La mayor&#237;a de los casos ocurrieron en ni&#241;os y en adultos j&#243;venes&#46; El factor de riesgo encontrado globalmente con mayor frecuencia fue el contacto con una persona infectada&#44; pero la distribuci&#243;n de factores de riesgo fue diferente en ni&#241;os y en adultos&#46;</p> <span class="elsevierStyleSectionTitle">Conclusiones</span><p id="spar0020" class="elsevierStyleSimplePara elsevierViewall">El descenso de la prevalencia de hepatitis A en nuestro pa&#237;s conlleva un aumento de poblaci&#243;n adulta susceptible&#46; Por este motivo&#44; la hepatitis A puede pasar de ser una enfermedad t&#237;picamente infantil a ser una enfermedad que afecte tambi&#233;n a adultos j&#243;venes&#44; en los que puede tener caracter&#237;sticas diferentes&#46; Este hecho debe tenerse en cuenta a la hora de dise&#241;ar una estrategia de vacunaci&#243;n&#46;</p>"
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        "resumen" => "<span class="elsevierStyleSectionTitle">Background</span><p id="spar0025" class="elsevierStyleSimplePara elsevierViewall">The decrease in the prevalence of hepatitis A in Spain may modify the characteristics of this infection because of the rise in the susceptible adult population&#46; The aim of this study was to determine the incidence of this disease&#44; as well as the epidemiological characteristics and the complications of patients diagnosed in the province of Guadalajara between 1991 and 1999&#46;</p> <span class="elsevierStyleSectionTitle">Patients and Methods</span><p id="spar0030" class="elsevierStyleSimplePara elsevierViewall">The inclusion criterion was the presence of specific IgM together with an increase in alanine aminotransferase concentrations and&#47;or symptoms compatible with acute hepatitis&#46;</p> <span class="elsevierStyleSectionTitle">Results</span><p id="spar0035" class="elsevierStyleSimplePara elsevierViewall">The mean incidence was 7&#46;13 cases&#47;105 inhabitants&#46; Considerable differences were found between years due to the presence of an outbreak&#46; Most cases occurred in children and young adults&#46; The most frequent risk factor found overall was contact with an infected individual but the distribution of risk factors differed between children and adults&#46;</p> <span class="elsevierStyleSectionTitle">Conclusions</span><p id="spar0040" class="elsevierStyleSimplePara elsevierViewall">The decrease in the prevalence of hepatitis A in Spain entails an increase in the susceptible adult population&#46; Consequently&#44; hepatitis A may cease to be a typically pediatric disease and may become one that also affects young adults in whom it may have different characteristics&#46; This consideration should be borne in mind when designing a vaccination strategy&#46;</p>"
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ISSN: 02105705
Idioma original: Español
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es en pt

¿Es usted profesional sanitario apto para prescribir o dispensar medicamentos?

Are you a health professional able to prescribe or dispense drugs?

Você é um profissional de saúde habilitado a prescrever ou dispensar medicamentos