array:24 [ "pii" => "S2387020616002072" "issn" => "23870206" "doi" => "10.1016/j.medcle.2016.03.017" "estado" => "S300" "fechaPublicacion" => "2015-11-20" "aid" => "3225" "copyright" => "Elsevier España, S.L.U.. All rights reserved" "copyrightAnyo" => "2015" "documento" => "simple-article" "crossmark" => 1 "subdocumento" => "cor" "cita" => "Med Clin. 2015;145:458" "abierto" => array:3 [ "ES" => false "ES2" => false "LATM" => false ] "gratuito" => false "lecturas" => array:2 [ "total" => 2 "PDF" => 2 ] "Traduccion" => array:1 [ "es" => array:19 [ "pii" => "S0025775315000640" "issn" => "00257753" "doi" => "10.1016/j.medcli.2015.01.007" "estado" => "S300" "fechaPublicacion" => "2015-11-20" "aid" => "3225" "copyright" => "Elsevier España, S.L.U." "documento" => "simple-article" "crossmark" => 1 "subdocumento" => "cor" "cita" => "Med Clin. 2015;145:458" "abierto" => array:3 [ "ES" => false "ES2" => false "LATM" => false ] "gratuito" => false "lecturas" => array:2 [ "total" => 18 "formatos" => array:2 [ "HTML" => 8 "PDF" => 10 ] ] "es" => array:10 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Carta al Editor</span>" "titulo" => "Neumonía por <span class="elsevierStyleItalic">Actinomyces odontolyticus</span> en un paciente con hipogammaglobulinemia IgA iatrogénica" "tienePdf" => "es" "tieneTextoCompleto" => "es" "paginas" => array:1 [ 0 => array:1 [ "paginaInicial" => "458" ] ] "titulosAlternativos" => array:1 [ "en" => array:1 [ "titulo" => "<span class="elsevierStyleItalic">Actinomyces odontolyticus</span> pneumonia in a patient with iatrogenic A-hypogammaglobulinemia" ] ] "contieneTextoCompleto" => array:1 [ "es" => true ] "contienePdf" => array:1 [ "es" => true ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "Fernando Nebrera Navarro, Carmen Ramirez Portero" "autores" => array:2 [ 0 => array:2 [ "nombre" => "Fernando" "apellidos" => "Nebrera Navarro" ] 1 => array:2 [ "nombre" => "Carmen" "apellidos" => "Ramirez Portero" ] ] ] ] ] "idiomaDefecto" => "es" "Traduccion" => array:1 [ "en" => array:9 [ "pii" => "S2387020616002072" "doi" => "10.1016/j.medcle.2016.03.017" "estado" => "S300" "subdocumento" => "" "abierto" => array:3 [ "ES" => false "ES2" => false "LATM" => false ] "gratuito" => false "lecturas" => array:1 [ "total" => 0 ] "idiomaDefecto" => "en" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2387020616002072?idApp=UINPBA00004N" ] ] "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0025775315000640?idApp=UINPBA00004N" "url" => "/00257753/0000014500000010/v1_201510290045/S0025775315000640/v1_201510290045/es/main.assets" ] ] "itemSiguiente" => array:19 [ "pii" => "S2387020616002084" "issn" => "23870206" "doi" => "10.1016/j.medcle.2016.03.018" "estado" => "S300" "fechaPublicacion" => "2015-11-20" "aid" => "3303" "copyright" => "Elsevier España, S.L.U." "documento" => "simple-article" "crossmark" => 1 "subdocumento" => "cor" "cita" => "Med Clin. 2015;145:458-9" "abierto" => array:3 [ "ES" => false "ES2" => false "LATM" => false ] "gratuito" => false "lecturas" => array:2 [ "total" => 1 "PDF" => 1 ] "en" => array:10 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Letter to the Editor</span>" "titulo" => "Patient information through the informed consent form" "tienePdf" => "en" "tieneTextoCompleto" => "en" "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "458" "paginaFinal" => "459" ] ] "titulosAlternativos" => array:1 [ "es" => array:1 [ "titulo" => "Información al paciente a través del documento de consentimiento informado" ] ] "contieneTextoCompleto" => array:1 [ "en" => true ] "contienePdf" => array:1 [ "en" => true ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "José María Prieto de Paula, Silvia Franco Hidalgo" "autores" => array:2 [ 0 => array:2 [ "nombre" => "José María" "apellidos" => "Prieto de Paula" ] 1 => array:2 [ "nombre" => "Silvia" "apellidos" => "Franco Hidalgo" ] ] ] ] ] "idiomaDefecto" => "en" "Traduccion" => array:1 [ "es" => array:9 [ "pii" => "S0025775315002535" "doi" => "10.1016/j.medcli.2015.01.030" "estado" => "S300" "subdocumento" => "" "abierto" => array:3 [ "ES" => false "ES2" => false "LATM" => false ] "gratuito" => false "lecturas" => array:1 [ "total" => 0 ] "idiomaDefecto" => "es" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0025775315002535?idApp=UINPBA00004N" ] ] "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2387020616002084?idApp=UINPBA00004N" "url" => "/23870206/0000014500000010/v1_201604230100/S2387020616002084/v1_201604230100/en/main.assets" ] "itemAnterior" => array:19 [ "pii" => "S2387020616002163" "issn" => "23870206" "doi" => "10.1016/j.medcle.2016.03.024" "estado" => "S300" "fechaPublicacion" => "2015-11-20" "aid" => "3270" "copyright" => "Elsevier España, S.L.U." "documento" => "article" "crossmark" => 1 "subdocumento" => "sco" "cita" => "Med Clin. 2015;145:452-7" "abierto" => array:3 [ "ES" => false "ES2" => false "LATM" => false ] "gratuito" => false "lecturas" => array:1 [ "total" => 0 ] "en" => array:10 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Special article</span>" "titulo" => "Electronic medical record in clinical trials of effectiveness of drugs integrated in clinical practice" "tienePdf" => "en" "tieneTextoCompleto" => "en" "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "452" "paginaFinal" => "457" ] ] "titulosAlternativos" => array:1 [ "es" => array:1 [ "titulo" => "Historia clínica electrónica en los ensayos clínicos de efectividad con medicamentos integrados en la práctica clínica" ] ] "contieneTextoCompleto" => array:1 [ "en" => true ] "contienePdf" => array:1 [ "en" => true ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "Antonio J. Carcas, Francisco Abad Santos, Luis Sánchez Perruca, Rafael Dal-Ré" "autores" => array:4 [ 0 => array:2 [ "nombre" => "Antonio J." "apellidos" => "Carcas" ] 1 => array:2 [ "nombre" => "Francisco" "apellidos" => "Abad Santos" ] 2 => array:2 [ "nombre" => "Luis" "apellidos" => "Sánchez Perruca" ] 3 => array:2 [ "nombre" => "Rafael" "apellidos" => "Dal-Ré" ] ] ] ] ] "idiomaDefecto" => "en" "Traduccion" => array:1 [ "es" => array:9 [ "pii" => "S0025775315001451" "doi" => "10.1016/j.medcli.2015.01.028" "estado" => "S300" "subdocumento" => "" "abierto" => array:3 [ "ES" => false "ES2" => false "LATM" => false ] "gratuito" => false "lecturas" => array:1 [ "total" => 0 ] "idiomaDefecto" => "es" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0025775315001451?idApp=UINPBA00004N" ] ] "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2387020616002163?idApp=UINPBA00004N" "url" => "/23870206/0000014500000010/v1_201604230100/S2387020616002163/v1_201604230100/en/main.assets" ] "en" => array:13 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Letter to the Editor</span>" "titulo" => "<span class="elsevierStyleItalic">Actinomyces odontolyticus</span> pneumonia in a patient with iatrogenic A-hypogammaglobulinemia" "tieneTextoCompleto" => true "saludo" => "<span class="elsevierStyleItalic">Dear Editor:</span>" "paginas" => array:1 [ 0 => array:1 [ "paginaInicial" => "458" ] ] "autores" => array:1 [ 0 => array:4 [ "autoresLista" => "Fernando Nebrera Navarro, Carmen Ramirez Portero" "autores" => array:2 [ 0 => array:4 [ "nombre" => "Fernando" "apellidos" => "Nebrera Navarro" "email" => array:1 [ 0 => "fernandonebrera@hotmail.com" ] "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">*</span>" "identificador" => "cor0005" ] ] ] 1 => array:2 [ "nombre" => "Carmen" "apellidos" => "Ramirez Portero" ] ] "afiliaciones" => array:1 [ 0 => array:2 [ "entidad" => "Servicio de Medicina Interna, Hospital de Formentera, Formentera, Spain" "identificador" => "aff0005" ] ] "correspondencia" => array:1 [ 0 => array:3 [ "identificador" => "cor0005" "etiqueta" => "⁎" "correspondencia" => "Corresponding author." ] ] ] ] "titulosAlternativos" => array:1 [ "es" => array:1 [ "titulo" => "Neumonía por <span class="elsevierStyleItalic">Actinomyces odontolyticus</span> en un paciente con hipogammaglobulinemia IgA iatrogénica" ] ] "textoCompleto" => "<span class="elsevierStyleSections"><p id="par0005" class="elsevierStylePara elsevierViewall"><span class="elsevierStyleItalic">Actinomyces</span> spp. is an uncommon cause of infection, especially at oral, cervicofacial, lung and chest wall levels, where it presents a special tropism due to the pleura.<a class="elsevierStyleCrossRefs" href="#bib0055"><span class="elsevierStyleSup">1–7</span></a> Those immunocompromised are particularly vulnerable, and in this sense, many of the reported cases are HIV-infected.<a class="elsevierStyleCrossRefs" href="#bib0055"><span class="elsevierStyleSup">1,8–10</span></a> It requires prolonged treatment, usually with penicillins and for a minimum of 6 months and often requires surgical drainage of the affected areas. This genre, <span class="elsevierStyleItalic">Actinomyces odontolyticus</span>, considered commensal flora of the oral cavity, is a very rare cause of pulmonary infection and very few cases have been published.<a class="elsevierStyleCrossRefs" href="#bib0055"><span class="elsevierStyleSup">1,2</span></a></p><p id="par0010" class="elsevierStylePara elsevierViewall">The case of a 68-year-old woman with a history of non-Hodgkin lymphoma treated with chemotherapy is presented (classical CHOP regimen, with tumor recurrence, and 3 cycles of rituximab-bendamustine with good response, and now in complete remission), which suffers persistent iatrogenic IgA deficiency with undetectable levels of IgA.</p><p id="par0015" class="elsevierStylePara elsevierViewall">In this context, pneumonia develops, and after a torpid progression and an incomplete response to levofloxacin and amoxicillin/clavulanate, finally undergoes bronchoscopy and bronchoalveolar lavage. The culture grows <span class="elsevierStyleItalic">Actinomyces odontolyticus</span>, which it is identified by 16S rDNA sequencing, with intermediate sensitivity to erythromycin and penicillin, imipenem and clindamycin. We present the case not only because the germ is so rare, but also because it presents an added therapeutic dilemma with no medical literature available to support it. This has to do with the treatment duration and the dose of the antibiotic and intravenous immunoglobulins in this clinical context of IgA deficiency. In our case, we chose amoxicillin 500<span class="elsevierStyleHsp" style=""></span>mg/8<span class="elsevierStyleHsp" style=""></span>h for 12 months and intravenous immunoglobulins every 3 weeks in the coldest months of the year, with a good clinical outcome.</p></span>" "pdfFichero" => "main.pdf" "tienePdf" => true "NotaPie" => array:1 [ 0 => array:2 [ "etiqueta" => "☆" "nota" => "<p class="elsevierStyleNotepara" id="npar0005">Please cite this article as: Nebrera Navarro F, Ramirez Portero C. Neumonía por <span class="elsevierStyleItalic">Actinomyces odontolyticus</span> en un paciente con hipogammaglobulinemia IgA iatrogénica. Med Clin (Barc). 2015;145:458.</p>" ] ] "bibliografia" => array:2 [ "titulo" => "References" "seccion" => array:1 [ 0 => array:2 [ "identificador" => "bibs0005" "bibliografiaReferencia" => array:10 [ 0 => array:3 [ "identificador" => "bib0055" "etiqueta" => "1" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "[Pulmonary actinomycosis secondary bacteremia in a HIV-infected patient] Spanish" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ 0 => "J.A. García-García" 1 => "J.E. Corzo" 2 => "M. Ramírez" 3 => "J.A. Pineda" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:4 [ "tituloSerie" => "Med Clin (Barc)" "fecha" => "2004" "volumen" => "123" "paginaInicial" => "599" ] ] ] ] ] ] 1 => array:3 [ "identificador" => "bib0060" "etiqueta" => "2" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Actinomyces odontolyticus thoracopulmonary infections. Two cases in lung and heart-lung transplant recipients and a review of the literature" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "A.G. Bassiri" 1 => "R.E. Girgis" 2 => "J. Theodore" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Chest" "fecha" => "1996" "volumen" => "109" "paginaInicial" => "1109" "paginaFinal" => "1111" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/8635341" "web" => "Medline" ] ] ] ] ] ] ] ] 2 => array:3 [ "identificador" => "bib0065" "etiqueta" => "3" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Actinomicosis" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "C. Betriu" 1 => "J.J. Picazo" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Med Clin (Barc)" "fecha" => "1999" "volumen" => "113" "paginaInicial" => "422" "paginaFinal" => "427" ] ] ] ] ] ] 3 => array:3 [ "identificador" => "bib0070" "etiqueta" => "4" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Actinomicosis" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "R.A. Smego" 1 => "G. Foglia" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Clin Infect Dis" "fecha" => "1998" "volumen" => "26" "paginaInicial" => "1255" "paginaFinal" => "1263" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/9636842" "web" => "Medline" ] ] ] ] ] ] ] ] 4 => array:3 [ "identificador" => "bib0075" "etiqueta" => "5" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Actinomicosis como causa de un derrame pleural" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "N. Avisbal-Portillo" 1 => "C. Rueda-Ríos" 2 => "A. Benítez-Domenech" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Arch Bronconeumol" "fecha" => "2002" "volumen" => "38" "paginaInicial" => "153" "paginaFinal" => "154" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/11900696" "web" => "Medline" ] ] ] ] ] ] ] ] 5 => array:3 [ "identificador" => "bib0080" "etiqueta" => "6" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Actinomyces como etiología del empiema" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:6 [ 0 => "A. Mateos Colino" 1 => "R. Monte Secades" 2 => "D. Ibáñez Alonso" 3 => "J. Santiago Toscano" 4 => "R. Rabuñal Rey" 5 => "J.L. Soilán del Cerro" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Arch Bronconeumol" "fecha" => "1995" "volumen" => "31" "paginaInicial" => "293" "paginaFinal" => "295" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/7627426" "web" => "Medline" ] ] ] ] ] ] ] ] 6 => array:3 [ "identificador" => "bib0085" "etiqueta" => "7" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Pleural effusion as the major manifestation of actinomycosis" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "E.L. Coodley" 1 => "R. Yoshinaka" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Chest" "fecha" => "1994" "volumen" => "106" "paginaInicial" => "1615" "paginaFinal" => "1617" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/7956435" "web" => "Medline" ] ] ] ] ] ] ] ] 7 => array:3 [ "identificador" => "bib0090" "etiqueta" => "8" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Actinomycosis in HIV infection: a review of a rare complication" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "S.I. Chaudhry" 1 => "J.S. Greenspan" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Int J STD AIDS" "fecha" => "2000" "volumen" => "11" "paginaInicial" => "349" "paginaFinal" => "355" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/10872906" "web" => "Medline" ] ] ] ] ] ] ] ] 8 => array:3 [ "identificador" => "bib0095" "etiqueta" => "9" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Thoracic actinomycosis and human immunodeficiency virus infection" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ 0 => "M.A. Ossorio" 1 => "C.L. Fields" 2 => "R.P. Byrd Jr." 3 => "T.M. Roy" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "South Med J" "fecha" => "1997" "volumen" => "90" "paginaInicial" => "1136" "paginaFinal" => "1138" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/9386058" "web" => "Medline" ] ] ] ] ] ] ] ] 9 => array:3 [ "identificador" => "bib0100" "etiqueta" => "10" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Actinomicosis pulmonar en varón de 47 años infectado por el virus de la inmunodeficiencia humana: a propósito de un caso" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:6 [ 0 => "F.J. Vera" 1 => "P. Berlinches" 2 => "O.J. Martínez" 3 => "J.A. García" 4 => "J. García" 5 => "L. Alemany" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Enferm Infecc Microbiol Clin" "fecha" => "2000" "volumen" => "18" "paginaInicial" => "480" "paginaFinal" => "481" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/11149175" "web" => "Medline" ] ] ] ] ] ] ] ] ] ] ] ] ] "idiomaDefecto" => "en" "url" => "/23870206/0000014500000010/v1_201604230100/S2387020616002072/v1_201604230100/en/main.assets" "Apartado" => array:4 [ "identificador" => "43309" "tipo" => "SECCION" "en" => array:2 [ "titulo" => "Letters to the Editor" "idiomaDefecto" => true ] "idiomaDefecto" => "en" ] "PDF" => "https://static.elsevier.es/multimedia/23870206/0000014500000010/v1_201604230100/S2387020616002072/v1_201604230100/en/main.pdf?idApp=UINPBA00004N&text.app=https://www.elsevier.es/" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2387020616002072?idApp=UINPBA00004N" ]
Journal Information
Vol. 145. Issue 10.
Pages 458 (November 2015)
Share
Download PDF
More article options
Vol. 145. Issue 10.
Pages 458 (November 2015)
Letter to the Editor
Actinomyces odontolyticus pneumonia in a patient with iatrogenic A-hypogammaglobulinemia
Neumonía por Actinomyces odontolyticus en un paciente con hipogammaglobulinemia IgA iatrogénica
Visits
6
Fernando Nebrera Navarro
, Carmen Ramirez Portero
Corresponding author
Servicio de Medicina Interna, Hospital de Formentera, Formentera, Spain
This item has received
Article information
These are the options to access the full texts of the publication Medicina Clínica (English Edition)
Subscriber
Subscribe
Purchase
Contact
Phone for subscriptions and reporting of errors
From Monday to Friday from 9 a.m. to 6 p.m. (GMT + 1) except for the months of July and August which will be from 9 a.m. to 3 p.m.
Calls from Spain
932 415 960
Calls from outside Spain
+34 932 415 960
E-mail