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"imagen" => "gr1.jpeg" "Alto" => 500 "Ancho" => 750 "Tamanyo" => 44186 ] ] "detalles" => array:1 [ 0 => array:3 [ "identificador" => "at0005" "detalle" => "Fig. " "rol" => "short" ] ] ] ] "textoCompleto" => "<span class="elsevierStyleSections"><p id="par0005" class="elsevierStylePara elsevierViewall">A 16-year-old male diagnosed with dermatomyositis in 2017 from the Gottron’s papules on the metacarpophalangeal joints and histologic appearance by biopsy, presented symptoms of asthenia, dyspnoea and loss of 4 kg in 4 weeks. The ANA titer lab report showed 1:160, so treatment was started with prednisone 20 mg/day and tapered for 2 months, as well as mycophenolate mofetil 1,500 mg/morning and 1,000 mg/night with clinical improvement. In 2018, ulcers appeared on the fingertips that required corticosteroid therapy with partial remission. In February 2019 the patient experienced clinical worsening with erythematous-violaceous lesions and ulcers on the fingertips (<a class="elsevierStyleCrossRefs" href="#fig0005">Figs. 1 and 2</a>). Lab tests showed positive anti-MDA5, so treatment was intensified with bosentan, acetylsalicylic acid, prednisone and mycophenolate mofetil with remission of the lesions.</p><elsevierMultimedia ident="fig0005"></elsevierMultimedia><elsevierMultimedia ident="fig0010"></elsevierMultimedia><p id="par0010" class="elsevierStylePara elsevierViewall">The presence of ulcers on the fingertips in patients diagnosed with dermatomyositis is associated with the presence of positive anti-MDA5 and worsening of the disease.</p></span>" "pdfFichero" => "main.pdf" "tienePdf" => true "NotaPie" => array:1 [ 0 => array:2 [ "etiqueta" => "☆" "nota" => "<p class="elsevierStyleNotepara" id="npar0005">Please cite this article as: Andamoyo Castañeda A, Pérez de Pedro I, Gómez Moyano E, Martínez Pilar L. Úlceras cutáneas en paciente con dermatomiositis amiopática anti-MDA5 positivo. 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Journal Information
Vol. 155. Issue 9.
Pages 423 (November 2020)
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Vol. 155. Issue 9.
Pages 423 (November 2020)
Image in medicine
Cutaneous ulceration in a patient with amyophatic dermatomyositis anti-MDA5 antibody positive
Úlceras cutáneas en paciente con dermatomiositis amiopática anti-MDA5 positivo
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