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array:23 [ "pii" => "S0025775300716150" "issn" => "00257753" "doi" => "10.1016/S0025-7753(00)71615-0" "estado" => "S300" "fechaPublicacion" => "2000-01-01" "aid" => "71615" "copyright" => "Elsevier España, S.L.. Todos los derechos reservados" "copyrightAnyo" => "2000" "documento" => "article" "crossmark" => 0 "subdocumento" => "fla" "cita" => "Med Clin. 2000;115:530-3" "abierto" => array:3 [ "ES" => false "ES2" => false "LATM" => false ] "gratuito" => false "lecturas" => array:2 [ "total" => 4201 "formatos" => array:3 [ "EPUB" => 5 "HTML" => 4012 "PDF" => 184 ] ] "itemSiguiente" => array:18 [ "pii" => "S0025775300716162" "issn" => "00257753" "doi" => "10.1016/S0025-7753(00)71616-2" "estado" => "S300" "fechaPublicacion" => "2000-01-01" "aid" => "71616" "copyright" => "Elsevier España, S.L." "documento" => "article" "crossmark" => 0 "subdocumento" => "fla" "cita" => "Med Clin. 2000;115:534-9" "abierto" => array:3 [ "ES" => false "ES2" => false "LATM" => false ] "gratuito" => false "lecturas" => array:2 [ "total" => 28608 "formatos" => array:3 [ "EPUB" => 6 "HTML" => 28411 "PDF" => 191 ] ] "es" => array:10 [ "idiomaDefecto" => true "titulo" => "Estudio prospectivo a 10 años sobre la incidencia y factores de riesgo de diabetes mellitus tipo 2" "tienePdf" => "es" "tieneTextoCompleto" => 0 "tieneResumen" => array:2 [ 0 => "es" 1 => "en" ] "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "534" "paginaFinal" => "539" ] ] "titulosAlternativos" => array:1 [ "en" => array:1 [ "titulo" => "Incidence and risk factors for type 2 diabetes mellitus: a 10-year prospective study" ] ] "contieneResumen" => array:2 [ "es" => true "en" => true ] "contienePdf" => array:1 [ "es" => true ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "José Antonio Vázquez, Sonia Gaztambide, Enrique Soto-Pedre" "autores" => array:3 [ 0 => array:2 [ "nombre" => "José" "apellidos" => "Antonio Vázquez" ] 1 => array:2 [ "nombre" => "Sonia" "apellidos" => "Gaztambide" ] 2 => array:2 [ "nombre" => "Enrique" "apellidos" => "Soto-Pedre" ] ] ] ] ] "idiomaDefecto" => "es" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0025775300716162?idApp=UINPBA00004N" "url" => "/00257753/0000011500000014/v1_201307291650/S0025775300716162/v1_201307291650/es/main.assets" ] "itemAnterior" => array:18 [ "pii" => "S0025775300716149" "issn" => "00257753" "doi" => "10.1016/S0025-7753(00)71614-9" "estado" => "S300" "fechaPublicacion" => "2000-01-01" "aid" => "71614" "copyright" => "Elsevier España, S.L." "documento" => "article" "crossmark" => 0 "subdocumento" => "fla" "cita" => "Med Clin. 2000;115:521-9" "abierto" => array:3 [ "ES" => false "ES2" => false "LATM" => false ] "gratuito" => false "lecturas" => array:2 [ "total" => 2743 "formatos" => array:3 [ "EPUB" => 6 "HTML" => 2570 "PDF" => 167 ] ] "es" => array:10 [ "idiomaDefecto" => true "titulo" => "Análisis de 500 trasplantes hepáticos en el Hospital de Bellvitge" "tienePdf" => "es" "tieneTextoCompleto" => 0 "tieneResumen" => array:2 [ 0 => "es" 1 => "en" ] "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "521" "paginaFinal" => "529" ] ] "titulosAlternativos" => array:1 [ "en" => array:1 [ "titulo" => "Analysis of 500 liver transplantations in the Bellvitge Hospital, Spain" ] ] "contieneResumen" => array:2 [ "es" => true "en" => true ] "contienePdf" => array:1 [ "es" => true ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "Eduardo Jaurrieta, Luis Casais, Juan Figueras, Emilio Ramos, Carmen Lama, Antonio Rafecas, Teresa Casanovas Taltavull, Juan Fabregat, Xavier Xiol, Jaume Torras, Carmen Baliellas, Antonio Sabaté, Gabriel Rufí, Carmen Benasco, Teodoro Casanovas, Teresa Serrano, Salvador Gil-Vernet, Isabel Sabaté, Juli Busquets" "autores" => array:19 [ 0 => array:2 [ "nombre" => "Eduardo" "apellidos" => "Jaurrieta" ] 1 => array:2 [ "nombre" => "Luis" "apellidos" => "Casais" ] 2 => array:2 [ "nombre" => "Juan" "apellidos" => "Figueras" ] 3 => array:2 [ "nombre" => "Emilio" "apellidos" => "Ramos" ] 4 => array:2 [ "nombre" => "Carmen" "apellidos" => "Lama" ] 5 => array:2 [ "nombre" => "Antonio" "apellidos" => "Rafecas" ] 6 => array:2 [ "nombre" => "Teresa" "apellidos" => "Casanovas Taltavull" ] 7 => array:2 [ "nombre" => "Juan" "apellidos" => "Fabregat" ] 8 => array:2 [ "nombre" => "Xavier" "apellidos" => "Xiol" ] 9 => array:2 [ "nombre" => "Jaume" "apellidos" => "Torras" ] 10 => array:2 [ "nombre" => "Carmen" "apellidos" => "Baliellas" ] 11 => array:2 [ "nombre" => "Antonio" "apellidos" => "Sabaté" ] 12 => array:2 [ "nombre" => "Gabriel" "apellidos" => "Rufí" ] 13 => array:2 [ "nombre" => "Carmen" "apellidos" => "Benasco" ] 14 => array:2 [ "nombre" => "Teodoro" "apellidos" => "Casanovas" ] 15 => array:2 [ "nombre" => "Teresa" "apellidos" => "Serrano" ] 16 => array:2 [ "nombre" => "Salvador" "apellidos" => "Gil-Vernet" ] 17 => array:2 [ "nombre" => "Isabel" "apellidos" => "Sabaté" ] 18 => array:2 [ "nombre" => "Juli" "apellidos" => "Busquets" ] ] ] ] ] "idiomaDefecto" => "es" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0025775300716149?idApp=UINPBA00004N" "url" => "/00257753/0000011500000014/v1_201307291650/S0025775300716149/v1_201307291650/es/main.assets" ] "es" => array:14 [ "idiomaDefecto" => true "titulo" => "Intoxicación por paraquat. Estudio de 29 casos y evaluación del tratamiento con la «pauta caribeña»" "tieneTextoCompleto" => 0 "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "530" "paginaFinal" => "533" ] ] "autores" => array:1 [ 0 => array:4 [ "autoresLista" => "Javier Botella de Maglia, José Enrique Belenguer Tarín" "autores" => array:2 [ 0 => array:3 [ "nombre" => "Javier" "apellidos" => "Botella de Maglia" "referencia" => array:2 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff0005" ] 1 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">*</span>" "identificador" => "cor0005" ] ] ] 1 => array:3 [ "nombre" => "José" "apellidos" => "Enrique Belenguer Tarín" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">b</span>" "identificador" => "aff0010" ] ] ] ] "afiliaciones" => array:2 [ 0 => array:3 [ "entidad" => "Unidades de Medicina Intensiva. Hospital La Fe Valencia." "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff0005" ] 1 => array:3 [ "entidad" => "Unidades de Medicina Intensiva. Hospital Gran Vía Castellón." "etiqueta" => "<span class="elsevierStyleSup">b</span>" "identificador" => "aff0010" ] ] "correspondencia" => array:1 [ 0 => array:3 [ "identificador" => "cor0005" "etiqueta" => "*" "correspondencia" => "Correspondencia: Dr. J. Botella de Maglia. Unidad de Medicina Intensiva. Hospital La Fe. Avda. de Campanar, 21. 46009 Valencia" ] ] ] ] "titulosAlternativos" => array:1 [ "en" => array:1 [ "titulo" => "Paraquat intoxication. A study of 29 cases with an evaluation of the effectivity of the «Caribbean scheme»" ] ] "pdfFichero" => "main.pdf" "tienePdf" => true "fechaRecibido" => "1998-12-21" "fechaAceptado" => "2000-06-08" "PalabrasClave" => array:1 [ "es" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Palabras clave" "identificador" => "xpalclavsec222529" "palabras" => array:6 [ 0 => "Intoxicación por insecticidas" 1 => "Paraquat" 2 => "Suicidio" 3 => "Hemoperfusión" 4 => "Ciclofosfamida" 5 => "Dexametasona" ] ] ] ] "tieneResumen" => true "resumen" => array:2 [ "es" => array:1 [ "resumen" => "<span class="elsevierStyleSectionTitle">Objetivos</span><p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Estudio de la intoxicación oral por paraquat y evaluación del efecto de la hemoperfu-sión y de la «pauta caribeña» (ciclofosfamida, dexametasona, furosemida y vitaminas B y C) sobre la mortalidad</p> <span class="elsevierStyleSectionTitle">Pacientes y método</span><p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">Estudio retrospectivo de 29 casos consecutivos ingresados en nuestra unidad de medicina intensiva en 17 años.</p> <span class="elsevierStyleSectionTitle">Resultados</span><p id="spar0015" class="elsevierStyleSimplePara elsevierViewall">a) 25 varones y cuatro mujeres ingirieron solución de paraquat al 20%, accidentalmente (4 sujetos) o con propósito suicida (25 sujetos). Este propósito fue particularmente fir-me en los varones de 50-66 años. La mayoría de los pacientes tuvieron vómitos y diarrea. Todos sufrieron causticaciones bucales y faríngeas. En algunos pacientes se detectó hipopotasemia al ingreso o aumento de las aminotransferasas, la bilirrubina, la amilasa o la creatincinasa. Veintidós pacientes sufrieron insuficiencia renal aguda, y 18 insuficiencia respiratoria. Veinte pacientes fallecieron (10 en las primeras 48 h y 10 entre los días 3 y 30); b) 16 pacientes fueron tratados con hemoperfusión con carbón activado; sobrevivieron 4 de los 16 tratados y 5 de los 13 no tratados (NS), y c) 18 pacientes fueron tratados con la «pauta caribeña». Salvo uno, los 11 sujetos que ingirieron más de 45 ml (tratados o no con la «pauta caribeña») murieron. De los que ingirieron < 45 ml, sobrevivieron 8 de los 12 tratados y ninguno de los seia no tratados (p < 0,05)</p> <span class="elsevierStyleSectionTitle">Conclusiones</span><p id="spar0020" class="elsevierStyleSimplePara elsevierViewall">La hemoperfusión no redujo la mortalidad de la intoxicación por paraquat. La «pauta caribeña» se asoció a una menor mortalidad en los sujetos que ingirieron < 45 ml de solución de paraquat al 20%</p>" ] "en" => array:1 [ "resumen" => "<span class="elsevierStyleSectionTitle">Background</span><p id="spar0025" class="elsevierStyleSimplePara elsevierViewall">To study clinical aspects of the oral paraquat intoxication and to assess the effectiveness of both the charcoal haemoperfusion and the so-called «Caribbean scheme» (cyclop-hosphamide, dexamethasone, furosemide and vitamins B and C) to reduce its mortality</p> <span class="elsevierStyleSectionTitle">Patients and method</span><p id="spar0030" class="elsevierStyleSimplePara elsevierViewall">Retrospective study of 29 consecutive cases admitted to our intensive care unit in 17 years</p> <span class="elsevierStyleSectionTitle">Results</span><p id="spar0035" class="elsevierStyleSimplePara elsevierViewall">a) Twenty five men and four women ingested 20% paraquat solution, either accidentally (4 subjects) or deliberately (25 subjects). The suicidal purpose was particularly strong among men aged 50-66 years. Most of patients had vomits and diarrhoea. All patients developed oral and parhyngeal caustic lesions. Hypokalaemia was detected on admission in 9 patients. Increased levels of serum aminotransferases, bilirubin, amylase or creatinkinase were detected in some patients. Twenty two patients developed acute renal failure and 18 patients respiratory failure. Twenty patients died (ten in the first 48 hours and ten between days 3 and 30); b) charcoal hae-moperfusion was performed on 16 patients; 4 of the 16 treated patients survived, versus 5 of the 13 non treated (p = NS), and c) the «Caribbean scheme» was applied on 18 patients. All but one of the 11 subjects who ingested > 45 ml (treated with the «Caribbean scheme» or not) died. Among those who ingested < 45 ml, 8 of the 12 treated patients survived, versus none of the 6 non treated ones (p < 0.05)</p> <span class="elsevierStyleSectionTitle">Conclusions</span><p id="spar0040" class="elsevierStyleSimplePara elsevierViewall">Charcoal haemoperfusion did not reduce mortality of paraquat. The «Caribbean sche-me» was associated with a lesser mortality in the subjects who ingested < 45 ml of 20% paraquat solution</p>" ] ] "bibliografia" => array:2 [ "titulo" => "Referencias Bibliográficas" "seccion" => array:1 [ 0 => array:2 [ "identificador" => "bibs0005" "bibliografiaReferencia" => array:47 [ 0 => array:3 [ "identificador" => "bib0005" "etiqueta" => "1." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Paraquat y la imprenta" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "A. 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