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Sin embargo, la utilidad clínica real de estos ensayos es, habitualmente, limitada en el caso de los antimicrobianos, dado que los pacientes incluidos suelen tener riesgo bajo de patógenos resistentes o problemáticos, y las condiciones de la vida real suelen ser distintas. Por ello, los estudios observacionales son un complemento imprescindible. Una vez comercializado un fármaco, comienza la fase de seguimiento postautorización. El estudio EUCORE es un registro multicéntrico europeo, retrospectivo postautorización y no comparativo, en el que se incluyó a los pacientes a los que se había administrado al menos una dosis de daptomicina. 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Metodología y objetivos del registro EUCORE
Methodology and aims of the European Cubicin® Outcome Registry and Experience (EUCORE) database
Jesús Rodríguez-Baño
Unidad Clínica de Enfermedades Infecciosas y Microbiología, Hospital Universitario Virgen Macarena, Sevilla. Departamento de Medicina, Universidad de Sevilla, Sevilla, España