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Physical examination revealed round urticarial plaques on her trunk and thighs, with characteristic involvement of the umbilical region (<a class="elsevierStyleCrossRef" href="#fig0005">Fig. 1</a>). A closer view showed typical annular disposition of bullae around erythematous plaques (<a class="elsevierStyleCrossRef" href="#fig0010">Fig. 2</a>). A skin biopsy exhibited spongiosis in combination with moderate superficial perivascular lymphocytic infiltrate with eosinophils. Direct immunofluorescence of perilesional skin exhibited linear deposition of complement (C3) along the basement membrane zone. Treatment with systemic corticosteroids was started with favorable response.</p><elsevierMultimedia ident="fig0005"></elsevierMultimedia><elsevierMultimedia ident="fig0010"></elsevierMultimedia><p id="par0010" class="elsevierStylePara elsevierViewall">Pemphigoid gestationis is a rare autoimmune bullous disorder arising exclusively during pregnancy. It is associated with the presence of IgG autoantibodies against basement membrane zone of the epithelium, mainly BP180 (type XVII collagen). Recurrence may occur with subsequent pregnancies. It is important to mention that neonates born to affected mothers may develop similar skin lesions.</p><span id="sec0005" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0005">Funding</span><p id="par0015" class="elsevierStylePara elsevierViewall">None.</p></span><span id="sec0010" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0010">Conflict of interest</span><p id="par0020" class="elsevierStylePara elsevierViewall">None.</p></span></span>" "textoCompletoSecciones" => array:1 [ "secciones" => array:2 [ 0 => array:2 [ "identificador" => "sec0005" "titulo" => "Funding" ] 1 => array:2 [ "identificador" => "sec0010" "titulo" => "Conflict of interest" ] ] ] "pdfFichero" => "main.pdf" "tienePdf" => true "multimedia" => array:2 [ 0 => array:6 [ "identificador" => "fig0005" "etiqueta" => "Fig. 1" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr1.jpeg" "Alto" => 1134 "Ancho" => 850 "Tamanyo" => 98558 ] ] ] 1 => array:6 [ "identificador" => "fig0010" "etiqueta" => "Fig. 2" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr2.jpeg" "Alto" => 675 "Ancho" => 900 "Tamanyo" => 56381 ] ] ] ] ] "idiomaDefecto" => "en" "url" => "/00257753/0000015400000008/v1_202004110627/S0025775319304932/v1_202004110627/en/main.assets" "Apartado" => array:4 [ "identificador" => "64289" "tipo" => "SECCION" "es" => array:2 [ "titulo" => "Imágenes médicas" "idiomaDefecto" => true ] "idiomaDefecto" => "es" ] "PDF" => "https://static.elsevier.es/multimedia/00257753/0000015400000008/v1_202004110627/S0025775319304932/v1_202004110627/en/main.pdf?idApp=UINPBA00004N&text.app=https://www.elsevier.es/" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0025775319304932?idApp=UINPBA00004N" ]
