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Departamento de Biología Animal. Facultad de Ciencias. Hospital Costa del Sol. Marbella. Málaga." "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff0005" ] 1 => array:3 [ "entidad" => "Universidad de Málaga. Servicio de Cirugía Ortopédica y Traumatología. Hospital Costa del Sol. Marbella. Málaga." "etiqueta" => "<span class="elsevierStyleSup">b</span>" "identificador" => "aff0010" ] ] ] ] "pdfFichero" => "main.pdf" "tienePdf" => true "bibliografia" => array:2 [ "titulo" => "Referencias Bibliográficas" "seccion" => array:1 [ 0 => array:2 [ "identificador" => "bibs0005" "bibliografiaReferencia" => array:89 [ 0 => array:3 [ "identificador" => "bib1" "etiqueta" => "1." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Limb regeneration: re-entering the cell cycle" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "D.L. Stocum" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Curr Biol" "fecha" => "1999" "volumen" => "9" "paginaInicial" => "644" "paginaFinal" => "646" ] ] ] ] ] ] 1 => array:3 [ "identificador" => "bib2" "etiqueta" => "2." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "New Tissues from Old" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "D.L. Stocum" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Science" "fecha" => "1997" "volumen" => "276" "paginaInicial" => "15" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/9122693" "web" => "Medline" ] ] ] ] ] ] ] ] 2 => array:3 [ "identificador" => "bib3" "etiqueta" => "3." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Amphibian Limb Regeneration: Rebuilding a Complex Structure" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "J.P. Brockes" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Science" "fecha" => "1997" "volumen" => "276" "paginaInicial" => "81" "paginaFinal" => "87" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/9082990" "web" => "Medline" ] ] ] ] ] ] ] ] 3 => array:3 [ "identificador" => "bib4" "etiqueta" => "4." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:1 [ "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "G.S. Stein" 1 => "J.B. Lian" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "LibroEditado" => array:4 [ "titulo" => "Molecular mechanisms mediating development and hormoneregulated expression of genes in osteoblasts: An integrate relationship of cell growth and differentiation. Cellular and molecular biology of bone" "paginaInicial" => "47" "paginaFinal" => "95" "serieFecha" => "1993" ] ] ] ] ] ] 4 => array:3 [ "identificador" => "bib5" "etiqueta" => "5." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "The development of the Vertebrate Limb" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "J. Hinchliffe" 1 => "D. Johnson" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "LibroEditado" => array:1 [ "serieFecha" => "1980" ] ] ] ] ] ] 5 => array:3 [ "identificador" => "bib6" "etiqueta" => "6." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Novel regulators of bone formation: Molecular clones and activities" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:6 [ 0 => "J.M. Wozney" 1 => "V. Rosen" 2 => "A.J. Celeste" 3 => "L.M. Mitsock" 4 => "M.J. Whitters" 5 => "R.W. Kriz" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Science" "fecha" => "1988" "volumen" => "242" "paginaInicial" => "1528" "paginaFinal" => "1534" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/3201241" "web" => "Medline" ] ] ] ] ] ] ] ] 6 => array:3 [ "identificador" => "bib7" "etiqueta" => "7." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "The Cell and Molecular Biology of Fracture Healing" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "T.A. Einhorn" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Clin Orthop Relat R" "fecha" => "1998" "volumen" => "355" "numero" => "Supl" "paginaInicial" => "7" "paginaFinal" => "21" ] ] ] ] ] ] 7 => array:3 [ "identificador" => "bib8" "etiqueta" => "8." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Concepts of Fracture Union, Delayed Union, and Nonunion" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "D. Marsh" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Clin Orthop Relat R" "fecha" => "1998" "volumen" => "355" "numero" => "Supl" "paginaInicial" => "22" "paginaFinal" => "30" ] ] ] ] ] ] 8 => array:3 [ "identificador" => "bib9" "etiqueta" => "9." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "The molecular basis of clinica heterogeneity of osteogenesis imperfecta: mutations in type I collagen genes have different effects on collagen processing" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "P. Byers" 1 => "J. Bonardio" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "LibroEditado" => array:4 [ "titulo" => "Genetic and metabolic diseases in pediatrics" "paginaInicial" => "56" "paginaFinal" => "90" "serieFecha" => "1985" ] ] ] ] ] ] 9 => array:3 [ "identificador" => "bib10" "etiqueta" => "10." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Diminution of the number of mesenchymal stem cells as a cause for skeletal aging" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "S.E. Haynesworth" 1 => "V.M. Goldberg" 2 => "A.I. Caplan" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "LibroEditado" => array:4 [ "titulo" => "Musculoskeletal soft-tissue aging: impact on mobility. Section 1, Chapter 7" "paginaInicial" => "80" "paginaFinal" => "86" "serieFecha" => "1994" ] ] ] ] ] ] 10 => array:3 [ "identificador" => "bib11" "etiqueta" => "11." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Bone regeneration by implantation of purified, culture-expanded human mesenchymal stem cells" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:6 [ 0 => "S.P. Bruder" 1 => "A.A. Kurth" 2 => "M. Shea" 3 => "W.C. Hayes" 4 => "N. Jaiswal" 5 => "S. Kadiyala" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1002/jor.1100160202" "Revista" => array:6 [ "tituloSerie" => "J Orthop Res" "fecha" => "1998" "volumen" => "16" "paginaInicial" => "155" "paginaFinal" => "162" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/9621889" "web" => "Medline" ] ] ] ] ] ] ] ] 11 => array:3 [ "identificador" => "bib12" "etiqueta" => "12." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Clinical use of marrow osteoprogenitor cells to stimulate osteogenesis" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "J.F. Connolly" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Clin Orthop Relat R" "fecha" => "1998" "volumen" => "355" "numero" => "Supl" "paginaInicial" => "257" "paginaFinal" => "266" ] ] ] ] ] ] 12 => array:3 [ "identificador" => "bib13" "etiqueta" => "13." "referencia" => array:1 [ 0 => array:1 [ "referenciaCompleta" => "Andrades JA, Nimni ME, Santamaría JA, Becerra J. Bone Marrow cells induced in vitro by a modified human TGF-ß1 form cartilage and bone when they are implanted in vivo. Bone. En prensa." ] ] ] 13 => array:3 [ "identificador" => "bib14" "etiqueta" => "14." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Biologic Enhancement of Fracture Repair" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "J.M. Lane" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Clin Orthop Relat R" "fecha" => "1998" "volumen" => "355" "numero" => "Supl" "paginaInicial" => "359" "paginaFinal" => "360" ] ] ] ] ] ] 14 => array:3 [ "identificador" => "bib15" "etiqueta" => "15." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Regional Gene Therapy" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "R.N. Rosier" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Clin Orthop Relat R" "fecha" => "1998" "volumen" => "355" "numero" => "Supl" "paginaInicial" => "361" "paginaFinal" => "363" ] ] ] ] ] ] 15 => array:3 [ "identificador" => "bib16" "etiqueta" => "16." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Cell and molecular engineering of bone regneration" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "A.I. Caplan" 1 => "S.P. Bruder" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "LibroEditado" => array:4 [ "titulo" => "Textbook of tissue engineering" "paginaInicial" => "603" "paginaFinal" => "618" "serieFecha" => "1997" ] ] ] ] ] ] 16 => array:3 [ "identificador" => "bib17" "etiqueta" => "17." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Linage of osteogenic cells and their relationshio to the stromal system" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "M. Owen" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "LibroEditado" => array:5 [ "paginaInicial" => "1" "paginaFinal" => "25" "serieVolumen" => "3" "serieTitulo" => "Bone and mineral research" "serieFecha" => "1985" ] ] ] ] ] ] 17 => array:3 [ "identificador" => "bib18" "etiqueta" => "18." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Mesenchymal stem cells" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "A.I. Caplan" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1002/jor.1100090504" "Revista" => array:6 [ "tituloSerie" => "J Orthop Res" "fecha" => "1991" "volumen" => "9" "paginaInicial" => "641" "paginaFinal" => "650" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/1870029" "web" => "Medline" ] ] ] ] ] ] ] ] 18 => array:3 [ "identificador" => "bib19" "etiqueta" => "19." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Monocytes stimulates fibroblastoid bone marrow stromal cells to produce multilineage hematopoietic growth factors" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:5 [ 0 => "V. Broudy" 1 => "S. Zuckerman" 2 => "S. Jemalani" 3 => "J. Fitchen" 4 => "G. Bagby" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Blood" "fecha" => "1986" "volumen" => "68" "paginaInicial" => "530" "paginaFinal" => "534" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/3524710" "web" => "Medline" ] ] ] ] ] ] ] ] 19 => array:3 [ "identificador" => "bib20" "etiqueta" => "20." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Iniciation and enhancement of bone formation: a review" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "J. Triffitt" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Acta Orthop Scand" "fecha" => "1987" "volumen" => "58" "paginaInicial" => "673" "paginaFinal" => "684" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/3327355" "web" => "Medline" ] ] ] ] ] ] ] ] 20 => array:3 [ "identificador" => "bib21" "etiqueta" => "21." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "The mesengenic process" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "A.I. Caplan" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Clin Plast Surg" "fecha" => "1994" "volumen" => "21" "paginaInicial" => "429" "paginaFinal" => "435" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/7924141" "web" => "Medline" ] ] ] ] ] ] ] ] 21 => array:3 [ "identificador" => "bib22" "etiqueta" => "22." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Marrow stromal cells as stem cells for nonhematopoietic tissues" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "D.J. Prockop" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Science" "fecha" => "1997" "volumen" => "276" "paginaInicial" => "71" "paginaFinal" => "74" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/9082988" "web" => "Medline" ] ] ] ] ] ] ] ] 22 => array:3 [ "identificador" => "bib23" "etiqueta" => "23." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:1 [ "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:6 [ 0 => "R.F. Pereira" 1 => "K.W. Halford" 2 => "M.D. O’Hara" 3 => "D.B. Leeper" 4 => "B.P. Sokolov" 5 => "M.D. Pollard" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:4 [ "tituloSerie" => "Culture adherent cells from marrow can serve as long-lasting precursor cells for bone, cartilage, and lung in irradiated mice. Proc Natl Acad Sci USA" "fecha" => "1995" "paginaInicial" => "4857" "paginaFinal" => "4861" ] ] ] ] ] ] 23 => array:3 [ "identificador" => "bib24" "etiqueta" => "24." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Mesenchymal cell-based repair of large full-thickness defects of articular cartilage" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:6 [ 0 => "S. Wakitani" 1 => "T. Goto" 2 => "S.J. Pineda" 3 => "R.G. Young" 4 => "J.M. Mansour" 5 => "A.I. Caplan" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "J Bone Joint Surg" "fecha" => "1994" "volumen" => "76" "paginaInicial" => "579" "paginaFinal" => "592" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/8150826" "web" => "Medline" ] ] ] ] ] ] ] ] 24 => array:3 [ "identificador" => "bib25" "etiqueta" => "25." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Birth and death of bone cells: basic regulatory mechanisms and implications for the pathogenesys and treatment of osteoporosis" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "S.C. Manologas" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Endocrin Rev" "fecha" => "2000" "volumen" => "21" "paginaInicial" => "115" "paginaFinal" => "137" ] ] ] ] ] ] 25 => array:3 [ "identificador" => "bib26" "etiqueta" => "26." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Polypeptide growth factors: targeted delivery sistems" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "M.E. Nimni" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Elsevier. Biomaterials" "fecha" => "1997" "volumen" => "18" "paginaInicial" => "1201" "paginaFinal" => "1225" ] ] ] ] ] ] 26 => array:3 [ "identificador" => "bib27" "etiqueta" => "27." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "BMPs: Actions in flesh and bone" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "A.J. Reddi" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Nat Med" "fecha" => "1997" "volumen" => "3" "paginaInicial" => "837" "paginaFinal" => "839" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/9256271" "web" => "Medline" ] ] ] ] ] ] ] ] 27 => array:3 [ "identificador" => "bib28" "etiqueta" => "28." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Potential role of insulinlike growth factors in fracture healing" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "S.B. Trippel" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Clin Orthop Relat R" "fecha" => "1998" "volumen" => "355" "numero" => "Supl" "paginaInicial" => "301" "paginaFinal" => "313" ] ] ] ] ] ] 28 => array:3 [ "identificador" => "bib29" "etiqueta" => "29." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Bone formation and repair" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "S.B. Trippel" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "LibroEditado" => array:4 [ "titulo" => "Biologic regulation of bone growth. Am Acad Orthop Surg" "paginaInicial" => "39" "paginaFinal" => "60" "serieFecha" => "1994" ] ] ] ] ] ] 29 => array:3 [ "identificador" => "bib30" "etiqueta" => "30." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Roles of calcium, serum, plasma and folic acid in the control of proliferation of normal and rouse sarcoma-virus infected chicken fibroblasts" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ 0 => "S.D. Balk" 1 => "J.F. Whitfield" 2 => "T. Youdale" 3 => "A.C. Brown" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Proc Natl Acad Sci USA" "fecha" => "1973" "volumen" => "70" "paginaInicial" => "675" "paginaFinal" => "679" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/4351800" "web" => "Medline" ] ] ] ] ] ] ] ] 30 => array:3 [ "identificador" => "bib31" "etiqueta" => "31." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "A platelet-dependent serum factor that stimulates the proliferation of external smooth muscle cells in vitro" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ 0 => "R. Ross" 1 => "J. Glomset" 2 => "B. Kariya" 3 => "L. Harker" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Proc Nat Acad Sci USA" "fecha" => "1974" "volumen" => "71" "paginaInicial" => "1207" "paginaFinal" => "1210" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/4208546" "web" => "Medline" ] ] ] ] ] ] ] ] 31 => array:3 [ "identificador" => "bib32" "etiqueta" => "32." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Growth factor receptor tyrosine kinases" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "Y. Yarden" 1 => "A. Ulrich" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1146/annurev.bi.57.070188.002303" "Revista" => array:6 [ "tituloSerie" => "Ann Rev Biochem" "fecha" => "1988" "volumen" => "57" "paginaInicial" => "443" "paginaFinal" => "478" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/3052279" "web" => "Medline" ] ] ] ] ] ] ] ] 32 => array:3 [ "identificador" => "bib33" "etiqueta" => "33." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Stimulation of osteogenesis by PDGF and TGF adsorbed on microcrystals of hydroxiapatite" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "J.J. McGill" 1 => "B.S. Strates" 2 => "M.H. McGuire" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "J Bone Min Res" "fecha" => "1990" "volumen" => "6" "numero" => "Supl 1" "paginaInicial" => "503" ] ] ] ] ] ] 33 => array:3 [ "identificador" => "bib34" "etiqueta" => "34." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Effects of fibroblast growth factors on deoxyribonucleic acid and collagen synthesis in rat parietal bone cells" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "T.L. McCarthy" 1 => "M. Centrella" 2 => "E. Canalis." ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1210/endo-125-4-2118" "Revista" => array:6 [ "tituloSerie" => "Endocrinology" "fecha" => "1989" "volumen" => "125" "paginaInicial" => "2118" "paginaFinal" => "2126" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/2791981" "web" => "Medline" ] ] ] ] ] ] ] ] 34 => array:3 [ "identificador" => "bib35" "etiqueta" => "35." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Recent developments in the cell biology of basic fibroblast growth factor" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "D.B. Rifkin" 1 => "D. Moscatelli" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Cell Biol" "fecha" => "1989" "volumen" => "109" "paginaInicial" => "1" "paginaFinal" => "6" ] ] ] ] ] ] 35 => array:3 [ "identificador" => "bib36" "etiqueta" => "36." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Potential role of fibroblast growth factor in enhancement of fracture healing" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ 0 => "M.L. Radomsky" 1 => "A.Y. Thompson" 2 => "R.C. Spiro" 3 => "J.W. Poser" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Clin Orthop" "fecha" => "1998" "volumen" => "355" "numero" => "Supl" "paginaInicial" => "283" "paginaFinal" => "293" ] ] ] ] ] ] 36 => array:3 [ "identificador" => "bib37" "etiqueta" => "37." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Effects of basic fibroblast growth factor on bone formation in growing rats" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "H. Nagai" 1 => "R. Tsukuda" 2 => "H. Mayahara" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Bone" "fecha" => "1995" "volumen" => "16" "paginaInicial" => "367" "paginaFinal" => "373" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/7786640" "web" => "Medline" ] ] ] ] ] ] ] ] 37 => array:3 [ "identificador" => "bib38" "etiqueta" => "38." "referencia" => array:1 [ 0 => array:1 [ "referenciaCompleta" => "Sasaki T, Watanabe C. Stimulation of osteoinduction in bone wound healing by high molecular hyaluronic acid. Bone 11995; 16: 9–15." ] ] ] 38 => array:3 [ "identificador" => "bib39" "etiqueta" => "39." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "The tronsforming growth factor beta superfamily: New members, new receptors, and new genetic tests of function in different organisms" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "D.M. Kingsley" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Genes Dev" "fecha" => "1994" "volumen" => "8" "paginaInicial" => "133" "paginaFinal" => "146" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/8299934" "web" => "Medline" ] ] ] ] ] ] ] ] 39 => array:3 [ "identificador" => "bib40" "etiqueta" => "40." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Transforming growth factor beta in fracture repair" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "M.P.G. Bostrom" 1 => "P. Asnis" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Clin Orthop Relat R" "fecha" => "1998" "volumen" => "355" "numero" => "Supl" "paginaInicial" => "124" "paginaFinal" => "131" ] ] ] ] ] ] 40 => array:3 [ "identificador" => "bib41" "etiqueta" => "41." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Inhibitory effects of the bone-derived growth factors osteoinductive factor and transforming growth factor-beta on isolated osteoclasts" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:6 [ 0 => "R.O. Oreffo" 1 => "L. Bonewald" 2 => "A. Kukita" 3 => "I.R. Garrett" 4 => "S.M. Seyedin" 5 => "D. Rosen" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1210/endo-126-6-3069" "Revista" => array:6 [ "tituloSerie" => "Endocrinology" "fecha" => "1990" "volumen" => "126" "paginaInicial" => "3069" "paginaFinal" => "3075" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/1693566" "web" => "Medline" ] ] ] ] ] ] ] ] 41 => array:3 [ "identificador" => "bib42" "etiqueta" => "42." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Transforming growth factor-ß1: induction of bone morphogenetic protein gene expression during endochondral bone formation in the baboon, and sinergystic interaction with osteogenic protein-1 (BMP-7)" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "N. Duneas" 1 => "J. Crooks" 2 => "U. Ripamonti" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Growth factors" "fecha" => "1998" "volumen" => "15" "paginaInicial" => "259" "paginaFinal" => "277" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/9714911" "web" => "Medline" ] ] ] ] ] ] ] ] 42 => array:3 [ "identificador" => "bib43" "etiqueta" => "43." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "The potential role of transforming growth factor beta in fracture healing" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "R.N. Rosier" 1 => "R.J. O’Keefe" 2 => "D.G. Hicks" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Clin Orthop Relat R" "fecha" => "1998" "volumen" => "355" "numero" => "Supl" "paginaInicial" => "294" "paginaFinal" => "300" ] ] ] ] ] ] 43 => array:3 [ "identificador" => "bib44" "etiqueta" => "44." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Bone: formation by autoinduction" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "M.R. Urist" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Science" "fecha" => "1965" "volumen" => "150" "paginaInicial" => "893" "paginaFinal" => "899" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/5319761" "web" => "Medline" ] ] ] ] ] ] ] ] 44 => array:3 [ "identificador" => "bib45" "etiqueta" => "45." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Initiation of fracture repair by bone morphogenetic proteints" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "A.H. Reddi" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Clin Orthop Relat R" "fecha" => "1998" "volumen" => "355" "paginaInicial" => "66" "paginaFinal" => "72" ] ] ] ] ] ] 45 => array:3 [ "identificador" => "bib46" "etiqueta" => "46." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Expression of bone morphogenetic proteins in fracture healing" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "MPG Bostrom" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Clin Orthop Relat R" "fecha" => "1998" "volumen" => "355" "numero" => "Supl" "paginaInicial" => "116" "paginaFinal" => "123" ] ] ] ] ] ] 46 => array:3 [ "identificador" => "bib47" "etiqueta" => "47." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Immunohistochemical observations on bone morphogenetic protein in normal and abnormal conditions" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "L.J. Yang" 1 => "Y. Jin" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Clin Orthop" "fecha" => "1990" "volumen" => "257" "paginaInicial" => "249" "paginaFinal" => "256" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/2379362" "web" => "Medline" ] ] ] ] ] ] ] ] 47 => array:3 [ "identificador" => "bib48" "etiqueta" => "48." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Immunohistochemical demonstration of bone morphogenetic protein- 2 and transforming growth factor-beta in the ossification of the posterior longitudinal ligament of the cervical spine" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:6 [ 0 => "H. Kawaguchi" 1 => "T. Kurokawa" 2 => "Y. Hoshino" 3 => "H. Kawahara" 4 => "E. Ogata" 5 => "T. Matsumoto" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Spine" "fecha" => "1992" "volumen" => "17" "paginaInicial" => "33" "paginaFinal" => "36" ] ] ] ] ] ] 48 => array:3 [ "identificador" => "bib49" "etiqueta" => "49." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Immunolocalization and expression of bone morphogenetic protein 2 and 4 in fracture healing" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:6 [ 0 => "M.P. Bostrom" 1 => "J.M. Lane" 2 => "W.S. Berberian" 3 => "A.A. Missri" 4 => "E. Tomin" 5 => "A. Weiland" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1002/jor.1100130309" "Revista" => array:6 [ "tituloSerie" => "J Orthop Res" "fecha" => "1995" "volumen" => "13" "paginaInicial" => "357" "paginaFinal" => "367" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/7602397" "web" => "Medline" ] ] ] ] ] ] ] ] 49 => array:3 [ "identificador" => "bib50" "etiqueta" => "50." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Use of bone morphogenetic protein-2 in the rabbit ulnar nonunion model" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:6 [ 0 => "M. Bostrom" 1 => "J.M. Lane" 2 => "E. Tomin" 3 => "M. Browne" 4 => "W. Berberian" 5 => "T. Turek" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Clin Orthop" "fecha" => "1996" "volumen" => "327" "paginaInicial" => "272" "paginaFinal" => "282" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/8641074" "web" => "Medline" ] ] ] ] ] ] ] ] 50 => array:3 [ "identificador" => "bib51" "etiqueta" => "51." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Acceleration of bone healing with OP-1 in a canine noncritical size deffect model" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "S.D. Cook" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "LibroEditado" => array:2 [ "titulo" => "Second Internacional OP-1 Conference" "serieFecha" => "1997" ] ] ] ] ] ] 51 => array:3 [ "identificador" => "bib52" "etiqueta" => "52." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "The application of cell biology to broken bones" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "D. Bonn" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1016/S0140-6736(05)75445-3" "Revista" => array:5 [ "tituloSerie" => "Lancet" "fecha" => "1999" "volumen" => "353" "paginaInicial" => "650" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/10030341" "web" => "Medline" ] ] ] ] ] ] ] ] 52 => array:3 [ "identificador" => "bib53" "etiqueta" => "53." "referencia" => array:1 [ 0 => array:1 [ "host" => array:1 [ 0 => array:1 [ "LibroEditado" => array:2 [ "titulo" => "Second Internacional OP-1 Conference" "serieFecha" => "1997" ] ] ] ] ] ] 53 => array:3 [ "identificador" => "bib54" "etiqueta" => "54." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:1 [ "titulo" => "International Conference on Bone Morphogenetic Proteins" ] ] "host" => array:1 [ 0 => array:1 [ "LibroEditado" => array:1 [ "serieFecha" => "2000" ] ] ] ] ] ] 54 => array:3 [ "identificador" => "bib55" "etiqueta" => "55." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Role of intergragmentory strain in fracture healing of a healing osteotomy" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:5 [ 0 => "E.J. Cheal" 1 => "K.A. Mansmann" 2 => "A.M. DiGioia III" 3 => "W.C. Hayes" 4 => "S.M. Perren" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1002/jor.1100090116" "Revista" => array:6 [ "tituloSerie" => "J Orthop Res" "fecha" => "1991" "volumen" => "9" "paginaInicial" => "131" "paginaFinal" => "142" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/1984043" "web" => "Medline" ] ] ] ] ] ] ] ] 55 => array:3 [ "identificador" => "bib56" "etiqueta" => "56." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Tissue in growth of replamineform implants" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "R. Chiroff" 1 => "J. Weber" 2 => "E. White" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:4 [ "tituloSerie" => "J Biomed Mater Res" "fecha" => "1975" "volumen" => "6" "paginaInicial" => "29" ] ] ] ] ] ] 56 => array:3 [ "identificador" => "bib57" "etiqueta" => "57." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "A New direction for osteoporosis research: A review and proposal" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "H. Frost" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Bone" "fecha" => "1991" "volumen" => "12" "paginaInicial" => "249" "paginaFinal" => "437" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/1793674" "web" => "Medline" ] ] ] ] ] ] ] ] 57 => array:3 [ "identificador" => "bib58" "etiqueta" => "58." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "The evaluation of a biphasic calcium phosphate ceramic for use in grafting long bone diaphyseal defects" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "D.C. Moore" 1 => "M.W. Chapman" 2 => "D. Manske" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1002/jor.1100050307" "Revista" => array:6 [ "tituloSerie" => "J Orthop Res" "fecha" => "1987" "volumen" => "5" "paginaInicial" => "356" "paginaFinal" => "365" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/3040949" "web" => "Medline" ] ] ] ] ] ] ] ] 58 => array:3 [ "identificador" => "bib59" "etiqueta" => "59." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Effect of porosity and fisicochemycal properties on the stability, resortion and strenght of calcium phosphate ceramics" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "R. De Groot" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Ann NY Acad Sci" "fecha" => "1998" "volumen" => "523" "paginaInicial" => "227" "paginaFinal" => "233" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/3382123" "web" => "Medline" ] ] ] ] ] ] ] ] 59 => array:3 [ "identificador" => "bib60" "etiqueta" => "60." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Interface mechanics and histomorphometric analysis of different types of bioceramics in canine bone" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "L. Nimb" 1 => "K. Gotfredsen" 2 => "J.S. Jensen" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Acta Orthop Scand" "fecha" => "1992" "volumen" => "63" "paginaInicial" => "28" "paginaFinal" => "32" ] ] ] ] ] ] 60 => array:3 [ "identificador" => "bib61" "etiqueta" => "61." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Treatment of acute fractures with a collagen-calcium phosphate graft material: a randomized clinical trial" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "M.W. Chapman" 1 => "R. Bucholz" 2 => "C.N. Cornell" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "J Bone Joint Surg" "fecha" => "1997" "volumen" => "79A" "paginaInicial" => "495" "paginaFinal" => "502" ] ] ] ] ] ] 61 => array:3 [ "identificador" => "bib62" "etiqueta" => "62." "referencia" => array:1 [ 0 => array:1 [ "referenciaCompleta" => "Hollinger JO, Battistone GC. Biodegradable bone repair materials: synthetic polymers and ceramics. Clin Orthop 986; 207: 290–305." ] ] ] 62 => array:3 [ "identificador" => "bib63" "etiqueta" => "63." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Poly (lactic acid) and poly (glicolic acid): orthopaedic surgery applications" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "C.T. Laurencin" 1 => "J.M. Lane" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "LibroEditado" => array:4 [ "titulo" => "Bone formation and repair" "paginaInicial" => "325" "paginaFinal" => "339" "serieFecha" => "1994" ] ] ] ] ] ] 63 => array:3 [ "identificador" => "bib64" "etiqueta" => "64." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Demineralized bone matrix mediates differentiation of bone marrow stromal cells in vitro: effect of age of cell donor" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:5 [ 0 => "J. Becerra" 1 => "J.A. Andrades" 2 => "D.C. Ertl" 3 => "N. Sorgente" 4 => "M.E. Nimni" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "J Bone Min Res" "fecha" => "1996" "volumen" => "11" "paginaInicial" => "1703" "paginaFinal" => "1714" ] ] ] ] ] ] 64 => array:3 [ "identificador" => "bib65" "etiqueta" => "65." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "A recombinant human TGF-ß1 fusion protein with collagen-binding domain promotes migration, growth, and differentiation of bone marrow mesenchymal cells" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:6 [ 0 => "J.A. Andrades" 1 => "B. Han" 2 => "J. Becerra" 3 => "N. Sorgente" 4 => "F.L. Hall" 5 => "M.E. Nimni" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1006/excr.1999.4528" "Revista" => array:6 [ "tituloSerie" => "Exp Cell Res" "fecha" => "1999" "volumen" => "250" "paginaInicial" => "485" "paginaFinal" => "498" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/10413602" "web" => "Medline" ] ] ] ] ] ] ] ] 65 => array:3 [ "identificador" => "bib66" "etiqueta" => "66." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Development of osteogenic tissue in diffusion chambers from early precursors cells in bone marrow of adult rats" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ 0 => "H.J. Mardon" 1 => "J. Bee" 2 => "K. Von der Mark" 3 => "M.E. Owen" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Cell Tissue Res" "fecha" => "1987" "volumen" => "250" "paginaInicial" => "157" "paginaFinal" => "165" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/3652158" "web" => "Medline" ] ] ] ] ] ] ] ] 66 => array:3 [ "identificador" => "bib67" "etiqueta" => "67." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Bone formation in vitro by stromal cells obtained from bone marrow of young adult rats" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "C. Maniatopoulos" 1 => "J. Sodek" 2 => "A.H. Melcher" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Cell Tissue Res" "fecha" => "1988" "volumen" => "254" "paginaInicial" => "317" "paginaFinal" => "330" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/3197089" "web" => "Medline" ] ] ] ] ] ] ] ] 67 => array:3 [ "identificador" => "bib68" "etiqueta" => "68." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Dexamethasone alters the subpopulation makeup of rat bone marrow stromal cell cultures" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "A. Herbertson" 1 => "J.E. Aubin" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1002/jbmr.5650100216" "Revista" => array:6 [ "tituloSerie" => "J Bone Miner Res" "fecha" => "1995" "volumen" => "10" "paginaInicial" => "285" "paginaFinal" => "294" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/7754809" "web" => "Medline" ] ] ] ] ] ] ] ] 68 => array:3 [ "identificador" => "bib69" "etiqueta" => "69." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Monoclonal antibodies reactive with human osteogenic cell surface antigens" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ 0 => "S.P. Bruder" 1 => "M.C. Horowitz" 2 => "J.D. Mosca" 3 => "S.E. Haynesworth" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Bone" "fecha" => "1997" "volumen" => "21" "paginaInicial" => "225" "paginaFinal" => "235" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/9276087" "web" => "Medline" ] ] ] ] ] ] ] ] 69 => array:3 [ "identificador" => "bib70" "etiqueta" => "70." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Mesenchymal stem cells in osteobiology and applied bone regeneration" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:6 [ 0 => "S.P. Bruder" 1 => "N. Jaiswal" 2 => "N.S. Ricalton" 3 => "J.D. Mosca" 4 => "K.H. Kraus" 5 => "S. Kadiyala" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Clin Orthop Relat R" "fecha" => "1998" "volumen" => "355" "numero" => "Supl" "paginaInicial" => "247" "paginaFinal" => "256" ] ] ] ] ] ] 70 => array:3 [ "identificador" => "bib71" "etiqueta" => "71." "referencia" => array:1 [ 0 => array:1 [ "referenciaCompleta" => "Lian JB, Gundberg CM. Osteocalcin: biochemical considerations and clinical applications. Clin Orthop 988; 226: 267–291." ] ] ] 71 => array:3 [ "identificador" => "bib72" "etiqueta" => "72." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Transforming growth factor beta is a bifunctional regulator of replication and collagen synthesis in osteoblast- enriched cell cultures from fetal rat bone" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "M. Centrella" 1 => "T.L. McCarthy" 2 => "E. Canalis" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "J Biol Chem" "fecha" => "1987" "volumen" => "262" "paginaInicial" => "2869" "paginaFinal" => "2874" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/3469200" "web" => "Medline" ] ] ] ] ] ] ] ] 72 => array:3 [ "identificador" => "bib73" "etiqueta" => "73." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Osteoblasts synthesize and respond to transforming growth factortype ß (TGF-beta) in vitro" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:6 [ 0 => "P.G. Robey" 1 => "M. Young" 2 => "K.C. Flanders" 3 => "N.S. Roche" 4 => "P. Kondaiah" 5 => "A.H. Reddi" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "J Cell Biol" "fecha" => "1987" "volumen" => "105" "paginaInicial" => "457" "paginaFinal" => "463" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/3475276" "web" => "Medline" ] ] ] ] ] ] ] ] 73 => array:3 [ "identificador" => "bib74" "etiqueta" => "74." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Transcriptional regulation os osteocalcin production by transforming growth factor-beta in rat osteoblast-like cells" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "M. Noda" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1210/endo-124-2-612" "Revista" => array:6 [ "tituloSerie" => "Endocrinology" "fecha" => "1989" "volumen" => "124" "paginaInicial" => "612" "paginaFinal" => "617" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/2783570" "web" => "Medline" ] ] ] ] ] ] ] ] 74 => array:3 [ "identificador" => "bib75" "etiqueta" => "75." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Transforming growth factor-beta and remodeling of bone" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ 0 => "M. Centrella" 1 => "T.L. McCarthy" 2 => "E. Canalis" 3 => "H. Connecticut" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:7 [ "tituloSerie" => "J Bone Joint Surg" "fecha" => "1991" "volumen" => "73" "numero" => "Supl A" "paginaInicial" => "1418" "paginaFinal" => "1428" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/1918129" "web" => "Medline" ] ] ] ] ] ] ] ] 75 => array:3 [ "identificador" => "bib76" "etiqueta" => "76." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Role of transforming growth factor-beta in bone remodeling" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "L.F. Bonewald" 1 => "R. Mundy" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Clin Orthop Relat R" "fecha" => "1990" "volumen" => "250" "paginaInicial" => "261" "paginaFinal" => "276" ] ] ] ] ] ] 76 => array:3 [ "identificador" => "bib77" "etiqueta" => "77." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Induction of rapid osteoblast differentiation in rat bone marrow stromal cell cultures by dexamethasone and BMP-2" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:5 [ 0 => "D.J. Rickard" 1 => "T.A. Sullivan" 2 => "B.J. Shenker" 3 => "P.S. Leboy" 4 => "I. Kazhdan" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1006/dbio.1994.1022" "Revista" => array:6 [ "tituloSerie" => "Dev Biol" "fecha" => "1994" "volumen" => "161" "paginaInicial" => "218" "paginaFinal" => "228" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/8293874" "web" => "Medline" ] ] ] ] ] ] ] ] 77 => array:3 [ "identificador" => "bib78" "etiqueta" => "78." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Regulation of human bone marrow-derived osteoprogenitor cells by osteogenic growth factors" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ 0 => "M.W. Long" 1 => "J.A. Robinson" 2 => "E.A. Ashcraft" 3 => "K.G. Mann" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1172/JCI117738" "Revista" => array:6 [ "tituloSerie" => "J Clin Invest" "fecha" => "1995" "volumen" => "95" "paginaInicial" => "881" "paginaFinal" => "887" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/7860771" "web" => "Medline" ] ] ] ] ] ] ] ] 78 => array:3 [ "identificador" => "bib79" "etiqueta" => "79." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Recombinant human osteogenic protein-1 (hOP-1) induces new bone formation in vivo with a specific activity comparable with natural bovine osteogenic protein and stimulates osteoblast proliferation and differentiation in vitro" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:6 [ 0 => "T.K. Sampath" 1 => "J.C. Maliakal" 2 => "P.V. Hauschka" 3 => "W.K. Jones" 4 => "H. Sasak" 5 => "R.F. Tucker" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "J Biol Chem" "fecha" => "1992" "volumen" => "267" "paginaInicial" => "20352" "paginaFinal" => "20362" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/1328198" "web" => "Medline" ] ] ] ] ] ] ] ] 79 => array:3 [ "identificador" => "bib80" "etiqueta" => "80." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Age-related changes in osteogenic stem cell in mice" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:6 [ 0 => "J. Bergman" 1 => "D. Gazit" 2 => "A.J. Kahn" 3 => "H. Gruber" 4 => "S. McDougall" 5 => "T.J. Hahn" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1002/jbmr.5650110504" "Revista" => array:6 [ "tituloSerie" => "J Bone Miner Res" "fecha" => "1996" "volumen" => "11" "paginaInicial" => "568" "paginaFinal" => "577" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/9157771" "web" => "Medline" ] ] ] ] ] ] ] ] 80 => array:3 [ "identificador" => "bib81" "etiqueta" => "81." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "The effect of aging on bone formation in porous hydroxyapatite: Biochemical and histological analysis" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:6 [ 0 => "K. Inoue" 1 => "H. Ohgushi" 2 => "T. Yoshikawa" 3 => "M. Okumura" 4 => "T. Sempuku" 5 => "S. Tamai" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1359/jbmr.1997.12.6.989" "Revista" => array:6 [ "tituloSerie" => "J Bone Miner Res" "fecha" => "1997" "volumen" => "12" "paginaInicial" => "989" "paginaFinal" => "994" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/9169360" "web" => "Medline" ] ] ] ] ] ] ] ] 81 => array:3 [ "identificador" => "bib82" "etiqueta" => "82." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Bone progenitor cell deficits and the ageassociated decline in bone repair capacity" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "R. Quarto" 1 => "D. Thoma" 2 => "T. Liang" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Calcif Tissue Int" "fecha" => "1995" "volumen" => "56" "paginaInicial" => "123" "paginaFinal" => "129" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/7736320" "web" => "Medline" ] ] ] ] ] ] ] ] 82 => array:3 [ "identificador" => "bib83" "etiqueta" => "83." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Mesenchymal stem cell surface antigen SB-10 corresponds to activated leukocyte cell adhesion molecule and is involved in osteogenic differentiation" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:6 [ 0 => "S.P. Bruder" 1 => "N.S. Ricalton" 2 => "R.E. Boynton" 3 => "T.J. Connolly" 4 => "N. Jaiswal" 5 => "J. Zaia" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1359/jbmr.1998.13.4.655" "Revista" => array:6 [ "tituloSerie" => "J Bone Miner Res" "fecha" => "1998" "volumen" => "13" "paginaInicial" => "655" "paginaFinal" => "663" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/9556065" "web" => "Medline" ] ] ] ] ] ] ] ] 83 => array:3 [ "identificador" => "bib84" "etiqueta" => "84." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Culture-expanded, bone marrow-derived mesenchymal stem cells can regenerate a critical-sized segmental bone defect" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "S. Kadiyala" 1 => "N. Jaiswal" 2 => "S.P. Bruder" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Tissue Enf" "fecha" => "1997" "volumen" => "3" "paginaInicial" => "173" "paginaFinal" => "185" ] ] ] ] ] ] 84 => array:3 [ "identificador" => "bib85" "etiqueta" => "85." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "The effects of cellular manipulation and TGF-ß in a composite bone graft" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "M. Liebergall" 1 => "R.G. Young" 2 => "N. Ozawa" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "LibroEditado" => array:4 [ "titulo" => "Bone formation and repair Chapter 26" "paginaInicial" => "367" "paginaFinal" => "377" "serieFecha" => "1994" ] ] ] ] ] ] 85 => array:3 [ "identificador" => "bib86" "etiqueta" => "86." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Induction of new bone by ceramic bovine bone with recombinant human bone morphogenetic protein 2 and transforming growth factor beta" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "X. Si" 1 => "Y. Jin" 2 => "L. Yang" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Int J Oral Maxillofac Surg" "fecha" => "1998" "volumen" => "27" "paginaInicial" => "310" "paginaFinal" => "314" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/9698182" "web" => "Medline" ] ] ] ] ] ] ] ] 86 => array:3 [ "identificador" => "bib87" "etiqueta" => "87." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Attachment of osteoblastic cells to hydroxyapatite crystals by a synthetic peptide (Glu-Pro-Arg- Gly-Asp-Thr) containing two functional sequences of bone sialoprotein" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ 0 => "R. Fujisawa" 1 => "M. Mizuno" 2 => "Y. Nodasaka" 3 => "Y. Kuboki" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "LibroEditado" => array:5 [ "paginaInicial" => "21" "paginaFinal" => "28" "serieVolumen" => "16" "serieTitulo" => "Verlag. Matrix Biology" "serieFecha" => "1997" ] ] ] ] ] ] 87 => array:3 [ "identificador" => "bib88" "etiqueta" => "88." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Potential role for gene therapy in the enhancement of fracture healing" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:6 [ 0 => "C. Niyibizi" 1 => "A. Baltzer" 2 => "C. Lattermann" 3 => "M. Oyama" 4 => "J.D. Whalen" 5 => "P.D. Robbins" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Clin Orthop Relat R" "fecha" => "1998" "volumen" => "355" "numero" => "Supl" "paginaInicial" => "148" "paginaFinal" => "153" ] ] ] ] ] ] 88 => array:3 [ "identificador" => "bib89" "etiqueta" => "89." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Potential role for direct gene transfer in the enhancement of fracture healing" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "S.A. Goldstein" 1 => "J. Bonadio" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Clin Orthop Relat R" "fecha" => "1998" "volumen" => "355" "paginaInicial" => "154" "paginaFinal" => "162" ] ] ] ] ] ] ] ] ] ] ] "idiomaDefecto" => "es" "url" => "/00257753/0000011600000001/v1_201307291411/S002577530171706X/v1_201307291411/es/main.assets" "Apartado" => array:4 [ "identificador" => "64287" "tipo" => "SECCION" "es" => array:2 [ "titulo" => "Revisión" "idiomaDefecto" => true ] "idiomaDefecto" => "es" ] "PDF" => "https://static.elsevier.es/multimedia/00257753/0000011600000001/v1_201307291411/S002577530171706X/v1_201307291411/es/main.pdf?idApp=UINPBA00004N&text.app=https://www.elsevier.es/" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S002577530171706X?idApp=UINPBA00004N" ]
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Regeneración ósea, terapia celular e ingeniería tisular
José Becerra, José Antonio Andrades, Jesús A. Santamaría
Departamento de Biología Celular y Genética. Hospital Costa del Sol. Marbella. Málaga.