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Editorial
Enfermedades mitocondriales: un diagnóstico todavía difícil
Francesc Cardellach
Autor para correspondencia
cardell@medicina.ub.es

Correspondencia: Servicio de Medicina Interna General. Hospital Clínic. Villarroel 170. 08036 Barcelona.
, Jordi Casademont
Grupo de Investigación Muscular. Servicio de Medicina Interna General. Hospital Clínic. Institut d'Investigacions Biomèdiques Agustí Pi i Sunyer (IDIBAPS). Facultad de Medicina. Universidad de Barcelona. Barcelona
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                        "link" => array:1 [
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                        "tituloSerie" => "Jpn J Human Genet"
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                        "paginaInicial" => "473"
                        "paginaFinal" => "487"
                        "link" => array:1 [
                          0 => array:2 [
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                            "web" => "Medline"
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              "referencia" => array:1 [
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                      "titulo" => "Reviews in molecular medicine&#46; Mitochondrial disorders"
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                          "etal" => false
                          "autores" => array:3 [
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                        "paginaFinal" => "72"
                        "link" => array:1 [
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                        "paginaInicial" => "291"
                        "paginaFinal" => "299"
                        "link" => array:1 [
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                            "web" => "Medline"
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                        "paginaFinal" => "98"
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                    0 => array:1 [
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                        "paginaFinal" => "184"
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                        "paginaInicial" => "135"
                        "paginaFinal" => "136"
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                        "paginaFinal" => "1949"
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                        "paginaFinal" => "970"
                        "link" => array:1 [
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                            4 => "M&#46; Fern&#225;ndez-Casta&#241;er"
                            5 => "J&#46; Soler"
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                      "titulo" => "Diabetes mitocondrial&#58; &#191;una diabetes distinta&#63;"
                      "autores" => array:1 [
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                          "etal" => false
                          "autores" => array:1 [
                            0 => "J&#46; Casademont"
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                    ]
                  ]
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                        "paginaInicial" => "96"
                        "paginaFinal" => "98"
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                    ]
                  ]
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            13 => array:3 [
              "identificador" => "bib0070"
              "etiqueta" => "14&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Utilidad del test de ejercicio cardiopulmonar en pacientes con miopat&#237;a mitocondrial"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "J&#46; Fern&#225;ndez"
                            1 => "T&#46; Montemayor"
                            2 => "J&#46; Bautista"
                            3 => "R&#46; M&#225;rquez"
                            4 => "L&#46; Jim&#233;nez"
                            5 => "J&#46; Arenas"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Med Clin &#40;Barc&#41;"
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                        "paginaInicial" => "121"
                        "paginaFinal" => "127"
                      ]
                    ]
                  ]
                ]
              ]
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            14 => array:3 [
              "identificador" => "bib0075"
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                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Mitochondrial diseases in man and mouse"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:1 [
                            0 => "D&#46;C&#46; Wallace"
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                    ]
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                    0 => array:1 [
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                        "tituloSerie" => "Science"
                        "fecha" => "1999"
                        "volumen" => "283"
                        "paginaInicial" => "1482"
                        "paginaFinal" => "1488"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/10066162"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            15 => array:3 [
              "identificador" => "bib0080"
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              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Ageing and muscle mitochondrial abnormalities"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:4 [
                            0 => "J&#46;M&#46; Grau"
                            1 => "J&#46; Casademont"
                            2 => "F&#46; Cardellach"
                            3 => "J&#46; Fern&#225;ndez-Sol&#224;"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1002/ana.410380224"
                      "Revista" => array:6 [
                        "tituloSerie" => "Ann Neurol"
                        "fecha" => "1995"
                        "volumen" => "38"
                        "paginaInicial" => "273"
                        "paginaFinal" => "274"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/7654080"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            16 => array:3 [
              "identificador" => "bib0085"
              "etiqueta" => "17&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Histological and biochemical assessment of mitochondrial function in dermatomyositis"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:6 [
                            0 => "O&#46; Mir&#243;"
                            1 => "J&#46; Casademont"
                            2 => "J&#46;M&#46; Grau"
                            3 => "D&#46; Jarreta"
                            4 => "A&#46; Urbano-M&#225;rquez"
                            5 => "F&#46; Cardellach"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Br J Rheumatol"
                        "fecha" => "1998"
                        "volumen" => "37"
                        "paginaInicial" => "1&#46;047"
                        "paginaFinal" => "1&#46;053"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/9973157"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            17 => array:3 [
              "identificador" => "bib0090"
              "etiqueta" => "18&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Skeletal muscle mitochondrial function in polymyalgia rheumatica and in giant cell arteritis"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:6 [
                            0 => "O&#46; Mir&#243;"
                            1 => "J&#46; Casademont"
                            2 => "D&#46; Jarreta"
                            3 => "J&#46;M&#46; Grau"
                            4 => "A&#46; Urbano-M&#225;rquez"
                            5 => "F&#46; Cardellach"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Rheumatology"
                        "fecha" => "1999"
                        "volumen" => "38"
                        "paginaInicial" => "568"
                        "paginaFinal" => "571"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/10402080"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            18 => array:3 [
              "identificador" => "bib0095"
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              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Absence of relationship between the level of electron transport chain activities and aging in human skeletal muscle"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "A&#46; Barrientos"
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                            2 => "A&#46; R&#246;tig"
                            3 => "O&#46; Mir&#243;"
                            4 => "A&#46; Urbano-M&#225;rquez"
                            5 => "P&#46; Rustin"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1006/bbrc.1996.1839"
                      "Revista" => array:6 [
                        "tituloSerie" => "Biochem Biophys Res Commun"
                        "fecha" => "1996"
                        "volumen" => "229"
                        "paginaInicial" => "536"
                        "paginaFinal" => "539"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/8954933"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            19 => array:3 [
              "identificador" => "bib0100"
              "etiqueta" => "20&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Biochemical parameters for the diagnosis of mitochondrial respiratory chain deficiency in humans&#44; and their lack of age-related changes"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "D&#46; Chretien"
                            1 => "J&#46; Gallego"
                            2 => "A&#46; Barrientos"
                            3 => "J&#46; Casademont"
                            4 => "F&#46; Cardellach"
                            5 => "A&#46; Munnich"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Biochem J"
                        "fecha" => "1998"
                        "volumen" => "329"
                        "paginaInicial" => "249"
                        "paginaFinal" => "254"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/9425106"
                            "web" => "Medline"
                          ]
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                      ]
                    ]
                  ]
                ]
              ]
            ]
            20 => array:3 [
              "identificador" => "bib0105"
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              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Mitocondriopat&#237;as secundarias"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "F&#46; Cardellach"
                            1 => "J&#46; Casademont"
                            2 => "A&#46; Urbano-M&#225;rquez"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:7 [
                        "tituloSerie" => "Rev Neurol"
                        "fecha" => "1998"
                        "volumen" => "26"
                        "numero" => "Supl 1&#41;&#58;"
                        "paginaInicial" => "S81"
                        "paginaFinal" => "S86"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/9810594"
                            "web" => "Medline"
                          ]
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                      ]
                    ]
                  ]
                ]
              ]
            ]
            21 => array:3 [
              "identificador" => "bib0110"
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              "referencia" => array:1 [
                0 => array:2 [
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                    0 => array:2 [
                      "titulo" => "Cytochrome c oxidase assay in minute amounts of human skeletal muscle using single wavelenght spectrophotometers"
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                          "etal" => false
                          "autores" => array:6 [
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                            4 => "A&#46; R&#246;tig"
                            5 => "P&#46; Rustin"
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                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "J Neurosci Meth"
                        "fecha" => "1998"
                        "volumen" => "80"
                        "paginaInicial" => "107"
                        "paginaFinal" => "111"
                      ]
                    ]
                  ]
                ]
              ]
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                0 => array:2 [
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                    0 => array:2 [
                      "titulo" => "Smoking disturbs mitochondrial respiratory chain function and enhances lipid peroxidation on human circulating lymphocytes"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:6 [
                            0 => "O&#46; Mir&#243;"
                            1 => "J&#46;R&#46; Alonso"
                            2 => "D&#46; Jarreta"
                            3 => "J&#46; Casademont"
                            4 => "A&#46; Urbano-M&#225;rquz"
                            5 => "F&#46; Cardellach"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Carcinogenesis"
                        "fecha" => "1999"
                        "volumen" => "20"
                        "paginaInicial" => "1331"
                        "paginaFinal" => "1336"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/10383908"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            23 => array:3 [
              "identificador" => "bib0120"
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              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Effects of general anesthetic procedures on mitochondrial function of human skeletal muscle"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "O&#46; Mir&#243;"
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                            2 => "J&#46;R&#46; Alonso"
                            3 => "J&#46; Casademont"
                            4 => "D&#46; Jarreta"
                            5 => "A&#46; Urbano-M&#225;rquez"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Eur J Clin Pharmacol"
                        "fecha" => "1999"
                        "volumen" => "55"
                        "paginaInicial" => "35"
                        "paginaFinal" => "41"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/10206082"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            24 => array:3 [
              "identificador" => "bib0125"
              "etiqueta" => "25&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Miopat&#237;as mitocondriales"
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                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "J&#46; Casademont"
                            1 => "J&#46;M&#46; Grau"
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                      ]
                    ]
                  ]
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                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Med Clin &#40;Barc&#41;"
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                        "volumen" => "91"
                        "paginaInicial" => "630"
                        "paginaFinal" => "635"
                      ]
                    ]
                  ]
                ]
              ]
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            25 => array:3 [
              "identificador" => "bib0130"
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                0 => array:2 [
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                    0 => array:2 [
                      "titulo" => "Clinical mitochondrial genetics"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:4 [
                            0 => "P&#46;F&#46; Chinnery"
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                            2 => "R&#46;M&#46; Andrews"
                            3 => "D&#46;M&#46; Turnbull"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "J Med Genet"
                        "fecha" => "1999"
                        "volumen" => "36"
                        "paginaInicial" => "425"
                        "paginaFinal" => "436"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/10874629"
                            "web" => "Medline"
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                      ]
                    ]
                  ]
                ]
              ]
            ]
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                0 => array:2 [
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                    0 => array:2 [
                      "titulo" => "Mitochondrial DNA and disease"
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                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
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                      ]
                    ]
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                        "numero" => "Supl 1"
                        "paginaInicial" => "17"
                        "paginaFinal" => "22"
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                    ]
                  ]
                ]
              ]
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