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Características epidemiológicas relacionadas con el cáncer de mama en mujeres pre y posmenopáusicas
Epidemiological characteristics of breast cancer development in pre and postmenopausal women
María Concepción Díez Collara, Paloma Ortega Molinab,
Autor para correspondencia
pomolina@eucmax.sim.ucm.es

Departamento de Medicina Preventiva Salud Pública e Historia de la Ciencia. Facultad de Medicina. Universidad Complutense de Madrid. Ciudad Universitaria. 28040 Madrid.
, Rosa Villanueva Orbaizb, Romana Albaladejo Vicenteb, Paloma Astasio Arbizab, Ma, Elisa Calle Purónb
a Servicio de Inspección Acreditación Sanitaria. Consejería de Sanidad. Comunidad de Madrid
b Departamento de Medicina Preventiva, Salud Pública e Historia de la Ciencia. Universidad Complutense de Madrid
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        "resumen" => "<span class="elsevierStyleSectionTitle">Fundamento</span><p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Caracterizar la relaci&#243;n entre el c&#225;ncer de mama distintas variables&#44; personales&#44; familiares sociodemogr&#225;ficas&#46; Para ello se analiz&#243; a todas las mujeres en conjunto&#44; clasificadas en dos grupos&#58; pre posmenop&#225;usicas&#46;</p> <span class="elsevierStyleSectionTitle">Poblaci&#243;n m&#233;todos</span><p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">Se realiz&#243; un estudio de casos controles&#44; equiparando caso control en funci&#243;n de la edad&#44; el &#225;rea sanitaria la actividad hormonal&#46; En total se estudiaron 274 casos 274 controles&#46; Las variables de estudio se obtuvieron mediante un cuestionario que recog&#237;a el nivel de estudios&#44; la historia reproductiva&#44; los antecedentes personales familiares los estilos de vida&#46; Se realiz&#243; un an&#225;lisis de regresi&#243;n log&#237;stica m&#250;ltiple en los grupos de estudio&#46;</p> <span class="elsevierStyleSectionTitle">Resultados</span><p id="spar0015" class="elsevierStyleSimplePara elsevierViewall">En las mujeres consideradas en conjunto&#44; la menarquia tard&#237;a se comport&#243; como variable de riesgo&#44; al igual que la primiparidad a&#241;osa los antecedentes familiares maternos&#44; como factor de protecci&#243;n el menor nivel de estudios el consumo de anticonceptivos orales&#46; Este &#250;ltimo patr&#243;n se repiti&#243; en la poblaci&#243;n posmenop&#225;usica&#44; con excepci&#243;n del consumo de anticonceptivos&#44; que no se mantuvo en el modelo final de regresi&#243;n&#46; En la poblaci&#243;n premeno-p&#225;usica&#44; se comportaron como factor de riesgo los antecedentes familiares maternos los ante-cedentes personales de enfermedad mamaria&#46; As&#237; mismo&#44; el nivel de estudios inferior apareci&#243; como factor de protecci&#243;n&#46;</p> <span class="elsevierStyleSectionTitle">Conclusiones</span><p id="spar0020" class="elsevierStyleSimplePara elsevierViewall">La presencia de antecedentes familiares maternos actu&#243; como variable de riesgo en todas las poblaciones&#44; constituyendo el primer factor en importancia en las mujeres preme-nop&#225;usicas&#46; En las dos categor&#237;as de estudio&#44; el menor nivel de estudios apareci&#243; como factor protector&#46;</p>"
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        "resumen" => "<span class="elsevierStyleSectionTitle">Background</span><p id="spar0025" class="elsevierStyleSimplePara elsevierViewall">To study the relation between breast cancer and different risk factors&#44; personal&#44; familial and demmographic factors&#46; An statistic and epidemiologic study was also carried on a whole population of women and then classified on pre and postmenopausal women&#46;</p> <span class="elsevierStyleSectionTitle">Patients and methods</span><p id="spar0030" class="elsevierStyleSimplePara elsevierViewall">A matched case-control study was performed based on age&#44; urban area and hormonal activity&#46; Total population was composed by 274 cases and same number of controls&#46; Studied variables were obtained by a questionnarire asking for study level&#44; reproductive and personal history&#44; familial considerations and lifestyles&#46; A multiples logistic regression model was made&#46;</p> <span class="elsevierStyleSectionTitle">Results</span><p id="spar0035" class="elsevierStyleSimplePara elsevierViewall">Over total population&#44; late menarcheal age&#44; late first pregnancy&#44; and familial history of breast cancer were shown as independent risk factors&#44; but a low study level&#44; and oral contraception were shown as protective factors&#46; This risk model was confirmed on postmenopausal women but no over premenopausal women&#44; so in this group&#44; main risk factors were familial breast cancer history and a medical history of bening breast disease&#46; Moreover&#44; the low study level was also a protective factor&#46;</p> <span class="elsevierStyleSectionTitle">Conclusions</span><p id="spar0040" class="elsevierStyleSimplePara elsevierViewall">Familial history of breast cancer in mothers or sisters was the main risk factor for breast cancer&#44; mainly in premenopausal women&#44; and low study level showed as protective factor&#46;</p>"
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