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Homocisteína y gestación
Eva-Llúcia López-Quesadaa,
Autor para correspondencia
evalq@hotmail.com

Correspondencia: Servicio de Ginecología y Obstetricia. Hospital Universitari Sant Joan de Déu. Passeig de Sant Joan de Déu, 2. 08950 Esplugues de Llobregat. Barcelona.
, M.ª Antonia Vilasecab, Santiago Gonzáleza
a Servicio de Ginecología y Obstetricia.
b Servicio de Bioquímica. Laboratorio de Metabolopatías. Hospital Universitari Sant Joan de Déu. Esplugues de Llobregat. Barcelona.
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                        "link" => array:1 [
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                            4 => "C&#46; Colom&#233;"
                            5 => "M&#46; Pineda"
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                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Eur J Paediatr Neurol"
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                        "volumen" => "3"
                        "paginaInicial" => "113"
                        "paginaFinal" => "117"
                        "link" => array:1 [
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                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/10461566"
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                0 => array:2 [
                  "contribucion" => array:1 [
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                      "titulo" => "Effects of folic acid and vitamin B6 supplementation on women with hyperhomocysteinemia and a history of preeclampsia or fetal grow restriction"
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                        0 => array:2 [
                          "etal" => false
                          "autores" => array:6 [
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                            4 => "H&#46; Van Geijn"
                            5 => "G&#46; Dekker"
                          ]
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                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Am J Obstet Gynecol"
                        "fecha" => "1998"
                        "volumen" => "179"
                        "paginaInicial" => "135"
                        "paginaFinal" => "139"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/9704778"
                            "web" => "Medline"
                          ]
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                    ]
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                ]
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              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Total homocysteine in plasma and amniotic fluid of pregnant women"
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                        0 => array:2 [
                          "etal" => false
                          "autores" => array:4 [
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                            1 => "P&#46; Wong"
                            2 => "J&#46; Zhon"
                            3 => "H&#46; Cook"
                          ]
                        ]
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                    ]
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                        "tituloSerie" => "Metabolism"
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                        "volumen" => "35"
                        "paginaInicial" => "889"
                        "paginaFinal" => "891"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/3762398"
                            "web" => "Medline"
                          ]
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                    ]
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                ]
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                    0 => array:2 [
                      "titulo" => "Maternal and fetal levels of methionine and homocysteine in early human pregnancy"
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                        0 => array:2 [
                          "etal" => false
                          "autores" => array:5 [
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                            1 => "N&#46;C&#46; Wathen"
                            2 => "T&#46;K&#46; Eskes"
                            3 => "B&#46; Van Raaij-Selten"
                            4 => "T&#46; Chard"
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                        ]
                      ]
                    ]
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                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Br J Obstet Gynaecol"
                        "fecha" => "1997"
                        "volumen" => "104"
                        "paginaInicial" => "10"
                        "paginaFinal" => "14"
                      ]
                    ]
                  ]
                ]
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                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Is homocysteine a biomarker for identifying women at risk of complications and adverse pregnancy outcomes&#63;"
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                          "etal" => false
                          "autores" => array:1 [
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                          ]
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                      ]
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                  ]
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                    0 => array:1 [
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                        "tituloSerie" => "Am J Clin Nutr"
                        "fecha" => "2000"
                        "volumen" => "71"
                        "paginaInicial" => "857"
                        "paginaFinal" => "858"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/10731488"
                            "web" => "Medline"
                          ]
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                ]
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              "identificador" => "bib0085"
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                      "titulo" => "La administraci&#243;n oral de 17-betaestradiol combinado de forma continua con didrogesterona reduce las concentraciones basales de homociste&#237;na en suero en mujeres posmenop&#225;usicas"
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                            3 => "C&#46; Jakobs"
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                          ]
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                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Acta Obstet Gynecol"
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                        "paginaInicial" => "214"
                        "paginaFinal" => "222"
                      ]
                    ]
                  ]
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              ]
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            17 => array:3 [
              "identificador" => "bib0090"
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                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Randomized&#44; double-blind&#44; placebo-controlled study of the effects of raloxifene and conjugated quine estrogen on plasma homocysteine levels in helthy postmenopausal women"
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                            3 => "G&#46; De ValkdeRoo"
                            4 => "C&#46; Jakobs"
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                    0 => array:1 [
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                        "tituloSerie" => "Fertil Steril"
                        "fecha" => "1998"
                        "volumen" => "70"
                        "paginaInicial" => "1085"
                        "paginaFinal" => "1089"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/9848300"
                            "web" => "Medline"
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                            1 => "M&#46;A&#46; Caudill"
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                            3 => "A&#46; Hutson"
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                            5 => "L&#46; Bailey"
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                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Obstet Gynecol"
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                        "paginaInicial" => "167"
                        "paginaFinal" => "170"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/9699744"
                            "web" => "Medline"
                          ]
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                      "titulo" => "Decreased serum homocysteine in pregnancy"
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                          "etal" => false
                          "autores" => array:3 [
                            0 => "A&#46; Andersson"
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                            2 => "L&#46; Brattstrom"
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                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Eur J Clin Chem Clin Biochem"
                        "fecha" => "1992"
                        "volumen" => "30"
                        "paginaInicial" => "377"
                        "paginaFinal" => "379"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/1511073"
                            "web" => "Medline"
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                0 => array:2 [
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                    0 => array:2 [
                      "titulo" => "Inherited thrombophilia and pregnancy"
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                          "autores" => array:2 [
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                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Curr Opin Obstet Gynecol"
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                        "volumen" => "10"
                        "paginaInicial" => "135"
                        "paginaFinal" => "144"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/9551309"
                            "web" => "Medline"
                          ]
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              "identificador" => "bib0110"
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                0 => array:2 [
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                    0 => array:2 [
                      "titulo" => "Folic acid suplementation and neural tube defects"
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                          "autores" => array:2 [
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                  "host" => array:1 [
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                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/1355205"
                            "web" => "Medline"
                          ]
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                0 => array:2 [
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                    0 => array:2 [
                      "titulo" => "Thermolabile variant of 5&#44;10-metilenetetrahydrofolate reductasa associated with low red-cell folates&#58; implication for folate intake recomendations"
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                          "etal" => false
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                        "paginaFinal" => "1593"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/9174561"
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                      "titulo" => "Genetic Selection and folate intake during pregnancy"
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                        "paginaFinal" => "1328"
                        "link" => array:1 [
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                        "paginaFinal" => "1013"
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                        "tituloSerie" => "Lancet"
                        "fecha" => "1997"
                        "volumen" => "350"
                        "paginaInicial" => "861"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/9310607"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            31 => array:3 [
              "identificador" => "bib0160"
              "etiqueta" => "32&#46;"
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                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Maternal homocysteine and chorionic vascularization in recurrent earlypregnancy loss"
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                        0 => array:2 [
                          "etal" => false
                          "autores" => array:6 [
                            0 => "W&#46;L&#46;D&#46;M&#46; Nelen"
                            1 => "J&#46; Bulten"
                            2 => "E&#46; Steegers"
                            3 => "H&#46; Blom"
                            4 => "A&#46; Hanselaar"
                            5 => "T&#46; Eskes"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Hum Reprod"
                        "fecha" => "2000"
                        "volumen" => "15"
                        "paginaInicial" => "954"
                        "paginaFinal" => "960"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/10739849"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            32 => array:3 [
              "identificador" => "bib0165"
              "etiqueta" => "33&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "A woman with five consecutive fetal deaths&#58; case report and retrospective analysis ofhyperhomocysteinemia prevalence in 100 consecutive women with recurrent miscarriages"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:6 [
                            0 => "I&#46; Quere"
                            1 => "H&#46; Bellet"
                            2 => "M&#46; Hoffet"
                            3 => "C&#46; Janbon"
                            4 => "P&#46; Mares"
                            5 => "J&#46;C&#46; Gris"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Fertil Steril"
                        "fecha" => "1998"
                        "volumen" => "69"
                        "paginaInicial" => "152"
                        "paginaFinal" => "153"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/9457954"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
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                    0 => array:2 [
                      "titulo" => "Serum folate and fetal grow retardation&#58; a matter of compliance&#63;"
                      "autores" => array:1 [
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                          "etal" => false
                          "autores" => array:3 [
                            0 => "R&#46;L&#46; Goldenberg"
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                            2 => "S&#46;P&#46; Cliver"
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                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Obstet Gynecol"
                        "fecha" => "1992"
                        "volumen" => "79"
                        "paginaInicial" => "719"
                        "paginaFinal" => "722"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/1565355"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
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                0 => array:2 [
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                    0 => array:2 [
                      "titulo" => "Underlying disorders associated with severe early-onset preeclampsia"
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                          "autores" => array:6 [
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                            3 => "P&#46;C&#46; Huijgens"
                            4 => "B&#46;U&#46; Von Blomberg"
                            5 => "C&#46; Jakobs"
                          ]
                        ]
                      ]
                    ]
                  ]
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                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Am J Obstet Gynecol"
                        "fecha" => "1995"
                        "volumen" => "173"
                        "paginaInicial" => "1042"
                        "paginaFinal" => "1048"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/7485291"
                            "web" => "Medline"
                          ]
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                      ]
                    ]
                  ]
                ]
              ]
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                          "autores" => array:3 [
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                    0 => array:2 [
                      "doi" => "10.1016/S0029-7844(97)00223-8"
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                        "tituloSerie" => "Obstet Gynecol"
                        "fecha" => "1997"
                        "volumen" => "90"
                        "paginaInicial" => "168"
                        "paginaFinal" => "171"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/9241286"
                            "web" => "Medline"
                          ]
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                      "titulo" => "Increased frequency of genetic thrombophilia in women with complications of Pregnancy"
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                            3 => "A&#46; Many"
                            4 => "A&#46; Bar-Am"
                            5 => "A&#46; Jaffa"
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                      ]
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                        "tituloSerie" => "N Engl J Med"
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                        "volumen" => "340"
                        "paginaInicial" => "9"
                        "paginaFinal" => "13"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/9878639"
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                      "titulo" => "Thrombophilias and adverse outcomes of pregnancy&#46; What should a clinician do&#63;"
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                          "etal" => false
                          "autores" => array:1 [
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                        "fecha" => "1999"
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                        "paginaInicial" => "50"
                        "paginaFinal" => "51"
                        "link" => array:1 [
                          0 => array:2 [
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                0 => array:2 [
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                      "titulo" => "Plasma homocysteine concentration is increased in preeclampsia and is associated with evidence of endothelial activation"
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                          "autores" => array:6 [
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                            4 => "R&#46; Ness"
                            5 => "W&#46; Grombleholme"
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                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
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                        "paginaInicial" => "1605"
                        "paginaFinal" => "1611"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/9855605"
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                      "titulo" => "Hyperhomocysteinemia as a risk factor for occlusive vascular disease"
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                          "autores" => array:3 [
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                    ]
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                  "host" => array:1 [
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                        "tituloSerie" => "Ann Rev Nutr"
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Información del artículo
ISSN: 00257753
Idioma original: Español
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es en pt

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Você é um profissional de saúde habilitado a prescrever ou dispensar medicamentos