Heparina de bajo peso molecular en el tratamiento de los síndromes coronarios agudos sin elevación del segmento ST: angina inestable e infarto de miocardio sin onda Q
Javier Borja
, Peri Olivella
Autor para correspondencia
javier.borja@eu.pnu.com
Correspondencia: Dr. J. Borja. Pharmacia &Upjohn, S.A. Ctra. de Rubí, 90-100. 08190 Sant Cugat del Vallès. Barcelona.
Correspondencia: Dr. J. Borja. Pharmacia &Upjohn, S.A. Ctra. de Rubí, 90-100. 08190 Sant Cugat del Vallès. Barcelona.
Departamento de Medicina. Pharmacia & Upjohn, S.A. Sant Cugat del Vallés. Barcelona.
Leído
1566
Vecesse ha leído el artículo
343
Total PDF
1223
Total HTML
Compartir estadísticas
array:23 [ "pii" => "S0025775300716319" "issn" => "00257753" "doi" => "10.1016/S0025-7753(00)71631-9" "estado" => "S300" "fechaPublicacion" => "2000-01-01" "aid" => "71631" "copyright" => "Elsevier España, S.L.. Todos los derechos reservados" "copyrightAnyo" => "2000" "documento" => "article" "crossmark" => 0 "subdocumento" => "rev" "cita" => "Med Clin. 2000;115:583-6" "abierto" => array:3 [ "ES" => false "ES2" => false "LATM" => false ] "gratuito" => false "lecturas" => array:2 [ "total" => 1369 "formatos" => array:3 [ "EPUB" => 9 "HTML" => 1222 "PDF" => 138 ] ] "itemSiguiente" => array:18 [ "pii" => "S0025775300716320" "issn" => "00257753" "doi" => "10.1016/S0025-7753(00)71632-0" "estado" => "S300" "fechaPublicacion" => "2000-01-01" "aid" => "71632" "copyright" => "Elsevier España, S.L." "documento" => "article" "crossmark" => 0 "subdocumento" => "cnf" "cita" => "Med Clin. 2000;115:587-97" "abierto" => array:3 [ "ES" => false "ES2" => false "LATM" => false ] "gratuito" => false "lecturas" => array:2 [ "total" => 3411 "formatos" => array:3 [ "EPUB" => 7 "HTML" => 3085 "PDF" => 319 ] ] "es" => array:7 [ "idiomaDefecto" => true "titulo" => "Consenso SEEDO'2000 para la evaluación del sobrepeso y la obesidad y el establecimiento de criterios de intervención terapéutica" "tienePdf" => "es" "tieneTextoCompleto" => 0 "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "587" "paginaFinal" => "597" ] ] "contienePdf" => array:1 [ "es" => true ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "" "autores" => array:1 [ 0 => array:1 [ "colaborador" => "Sociedad Española para el Estudio de la Obesidad (SEEDO)" ] ] ] ] ] "idiomaDefecto" => "es" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0025775300716320?idApp=UINPBA00004N" "url" => "/00257753/0000011500000015/v1_201307291747/S0025775300716320/v1_201307291747/es/main.assets" ] "itemAnterior" => array:18 [ "pii" => "S0025775300716307" "issn" => "00257753" "doi" => "10.1016/S0025-7753(00)71630-7" "estado" => "S300" "fechaPublicacion" => "2000-01-01" "aid" => "71630" "copyright" => "Elsevier España, S.L." "documento" => "article" "crossmark" => 0 "subdocumento" => "sco" "cita" => "Med Clin. 2000;115:579-82" "abierto" => array:3 [ "ES" => false "ES2" => false "LATM" => false ] "gratuito" => false "lecturas" => array:2 [ "total" => 6577 "formatos" => array:3 [ "EPUB" => 6 "HTML" => 6255 "PDF" => 316 ] ] "es" => array:7 [ "idiomaDefecto" => true "titulo" => "¿Qué puede ayudarnos a morir en paz?" "tienePdf" => "es" "tieneTextoCompleto" => 0 "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "579" "paginaFinal" => "582" ] ] "contienePdf" => array:1 [ "es" => true ] "autores" => array:2 [ 0 => array:2 [ "autoresLista" => "Ramón Bayés, Joaquín T. Limonero, Eva Romero" "autores" => array:3 [ 0 => array:2 [ "nombre" => "Ramón" "apellidos" => "Bayés" ] 1 => array:2 [ "nombre" => "Joaquín T." "apellidos" => "Limonero" ] 2 => array:2 [ "nombre" => "Eva" "apellidos" => "Romero" ] ] ] 1 => array:2 [ "autoresLista" => "Pilar Arranz" "autores" => array:1 [ 0 => array:2 [ "nombre" => "Pilar" "apellidos" => "Arranz" ] ] ] ] ] "idiomaDefecto" => "es" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0025775300716307?idApp=UINPBA00004N" "url" => "/00257753/0000011500000015/v1_201307291747/S0025775300716307/v1_201307291747/es/main.assets" ] "es" => array:11 [ "idiomaDefecto" => true "titulo" => "Heparina de bajo peso molecular en el tratamiento de los síndromes coronarios agudos sin elevación del segmento ST: angina inestable e infarto de miocardio sin onda Q" "tieneTextoCompleto" => 0 "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "583" "paginaFinal" => "586" ] ] "autores" => array:1 [ 0 => array:4 [ "autoresLista" => "Javier Borja, Peri Olivella" "autores" => array:2 [ 0 => array:4 [ "nombre" => "Javier" "apellidos" => "Borja" "email" => array:1 [ 0 => "javier.borja@eu.pnu.com" ] "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">*</span>" "identificador" => "cor0005" ] ] ] 1 => array:2 [ "nombre" => "Peri" "apellidos" => "Olivella" ] ] "afiliaciones" => array:1 [ 0 => array:1 [ "entidad" => "Departamento de Medicina. Pharmacia & Upjohn, S.A. Sant Cugat del Vallés. Barcelona." ] ] "correspondencia" => array:1 [ 0 => array:3 [ "identificador" => "cor0005" "etiqueta" => "*" "correspondencia" => "Correspondencia: Dr. J. Borja. Pharmacia &Upjohn, S.A. Ctra. de Rubí, 90-100. 08190 Sant Cugat del Vallès. Barcelona." ] ] ] ] "miscelanea" => "Heparina de bajo peso molecular; Síndrome coronario agudo; Angina inestable; Infarto de miocardio sin onda Q" "pdfFichero" => "main.pdf" "tienePdf" => true "fechaRecibido" => "2000-06-05" "fechaAceptado" => "2000-06-09" "bibliografia" => array:2 [ "titulo" => "Referencias Bibliografía" "seccion" => array:1 [ 0 => array:2 [ "identificador" => "bibs0005" "bibliografiaReferencia" => array:22 [ 0 => array:3 [ "identificador" => "bib0005" "etiqueta" => "1." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Low molecular weight heparin in the management of unstable angina/non-Q-wave myocardial infarction" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "M.C. Cohen" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Sem Thromb Hemost" "fecha" => "1999" "volumen" => "25" "paginaInicial" => "113" "paginaFinal" => "121" ] ] ] ] ] ] 1 => array:3 [ "identificador" => "bib0010" "etiqueta" => "2." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Antithrombotic agents in coronary artery disease" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:6 [ 0 => "J.A. Cairns" 1 => "P. Théroux" 2 => "H.D. Lewis" 3 => "M. Ezekowitz" 4 => "T.W. Meade" 5 => "G.C. Sutton" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Chest" "fecha" => "1998" "volumen" => "114" "paginaInicial" => "611S" "paginaFinal" => "633S" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/9822067" "web" => "Medline" ] ] ] ] ] ] ] ] 2 => array:3 [ "identificador" => "bib0015" "etiqueta" => "3." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Guías de actuación clínica de la Sociedad Española de Cardiología. Recomendaciones para el uso del tratamiento antitrombótico en cardiología" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "M. Heras" 1 => "A. Fernández Ortiz" 2 => "J.A. Gómez Guindal" 3 => "J.A. Iriarte" 4 => "R.M. Lidón" 5 => "F. Pérez Gómez" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Rev Esp Cardiol" "fecha" => "1999" "volumen" => "52" "paginaInicial" => "801" "paginaFinal" => "820" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/10563156" "web" => "Medline" ] ] ] ] ] ] ] ] 3 => array:3 [ "identificador" => "bib0020" "etiqueta" => "4." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Low molecular weight heparin or aspirin in the treatment of unstable angina and silent ischemia" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "E.P. Gurfinkel" 1 => "E.J. Manos" 2 => "R.I. Mejaíl" 3 => "M.A. Cerdá" 4 => "E.A. Duronto" 5 => "C.N. García" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "J Am Coll Cardiol" "fecha" => "1995" "volumen" => "26" "paginaInicial" => "313" "paginaFinal" => "318" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/7608429" "web" => "Medline" ] ] ] ] ] ] ] ] 4 => array:3 [ "identificador" => "bib0025" "etiqueta" => "5." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:1 [ "titulo" => "Fragmin during Instability in Coronary Artery Disease (FRISC) study group. Low-molecular-weight heparin during instability in coronary artery disease" ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Lancet" "fecha" => "1996" "volumen" => "347" "paginaInicial" => "561" "paginaFinal" => "568" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/8596317" "web" => "Medline" ] ] ] ] ] ] ] ] 5 => array:3 [ "identificador" => "bib0030" "etiqueta" => "6." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:1 [ "titulo" => "Fragmin in Unstable Coronary Artery Disease Study (FRIC). Comparison of low-molecular-weight heparin with unfractionated heparin acutely and with placebo for 6 weeks in the management of unstable coronary artery disease" ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Circulation" "fecha" => "1997" "volumen" => "96" "paginaInicial" => "61" "paginaFinal" => "68" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/9236418" "web" => "Medline" ] ] ] ] ] ] ] ] 6 => array:3 [ "identificador" => "bib0035" "etiqueta" => "7." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "A comparison of low-molecular-weight heparin with unfractionated heparin for unstable coronary artery disease" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "M. Cohen" 1 => "C. Demers" 2 => "E.P. Gurfinkel" 3 => "A.G.G. Turpie" 4 => "G.J. Fromell" 5 => "S. Goodman" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1056/NEJM199708143370702" "Revista" => array:6 [ "tituloSerie" => "N Engl J Med" "fecha" => "1997" "volumen" => "337" "paginaInicial" => "447" "paginaFinal" => "452" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/9250846" "web" => "Medline" ] ] ] ] ] ] ] ] 7 => array:3 [ "identificador" => "bib0040" "etiqueta" => "8." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:1 [ "titulo" => "Fragmin and Fast Revascularization during InStability in Coronary artery disease (FRISC II) Investigators. Long-term low-molecular-mass heparin in unstable coronary artery disease: FRISC II prospective randomised multicentre study" ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Lancet" "fecha" => "1999" "volumen" => "354" "paginaInicial" => "701" "paginaFinal" => "707" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/10475180" "web" => "Medline" ] ] ] ] ] ] ] ] 8 => array:3 [ "identificador" => "bib0045" "etiqueta" => "9." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Enoxaparin prevents death and cardiac ischemic events in unstable angina/non-Q-wave myocardial infarction. Results of the Thrombolysis in Myocardial Infarction (TIMI) 11B Trial" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "E.M. Antman" 1 => "C.H. McCabe" 2 => "E.P. Gurfinkel" 3 => "A.G.G. Turpie" 4 => "P.J.L.M. Bernink" 5 => "D. Salein" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Circulation" "fecha" => "1999" "volumen" => "100" "paginaInicial" => "1593" "paginaFinal" => "1601" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/10517729" "web" => "Medline" ] ] ] ] ] ] ] ] 9 => array:3 [ "identificador" => "bib0050" "etiqueta" => "10." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:1 [ "titulo" => "The FRAX.I.S. Study Group. Comparison of two treatment durations (6 days and 14 days) of a low molecular weight heparin with a 6-day treatment of unfractionated heparin in the initial management of unstable angina or non-Q-wave myocardial infarction: FRAXIS (FRAXiparine in Ischaemic Syndrome)" ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1053/euhj.1999.1879" "Revista" => array:6 [ "tituloSerie" => "Eur Heart J" "fecha" => "1999" "volumen" => "20" "paginaInicial" => "1553" "paginaFinal" => "1562" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/10529323" "web" => "Medline" ] ] ] ] ] ] ] ] 10 => array:3 [ "identificador" => "bib0055" "etiqueta" => "11." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Troponin T identifies patients with unstable coronary artery disease who benefit from long-term antitrombotic protection" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "B. Lindahl" 1 => "P. Venge" 2 => "L. Wallentin" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "J Am Coll Cardiol" "fecha" => "1997" "volumen" => "29" "paginaInicial" => "43" "paginaFinal" => "48" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/8996293" "web" => "Medline" ] ] ] ] ] ] ] ] 11 => array:3 [ "identificador" => "bib0060" "etiqueta" => "12." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "One year follow-up of the ESSENCE trial (enoxaparin vs heparin in unstable angina/non Q wave myocardial infarction): sustained clinical benefit" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "S. Goodman" 1 => "A. Langer" 2 => "C. Demers" 3 => "A. Turpie" 4 => "F. Bigonzi" 5 => "D. Radley" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Can J Cardiol" "fecha" => "1998" "volumen" => "14" "numero" => "F" "paginaInicial" => "122" ] ] ] ] ] ] 12 => array:3 [ "identificador" => "bib0065" "etiqueta" => "13." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Long term treatment with low molecular weight heparin (dalteparin) reduces cardiac events in unstable coronary artery disease (UCAD) with troponin-T elevation: a FRISC II substudy" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "B. Lindhal" 1 => "E. Diderholm" 2 => "F. Kontny" 3 => "B. Lagervist" 4 => "S. Husted" 5 => "E. Stahle" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Circulation" "fecha" => "1999" "volumen" => "100" "numero" => "I" "paginaInicial" => "498" ] ] ] ] ] ] 13 => array:3 [ "identificador" => "bib0070" "etiqueta" => "14." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Unfractionated heparin and low-molecular-weight heparin in acute coronary syndrome without ST elevation: a meta-analysis" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:6 [ 0 => "J.W. Eikelboom" 1 => "S.S. Anand" 2 => "K. Malmberg" 3 => "J.I. Weitz" 4 => "J.S. Ginsberg" 5 => "S. Yusuf" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1016/S0140-6736(00)02324-2" "Revista" => array:6 [ "tituloSerie" => "Lancet" "fecha" => "2000" "volumen" => "355" "paginaInicial" => "1936" "paginaFinal" => "1942" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/10859038" "web" => "Medline" ] ] ] ] ] ] ] ] 14 => array:3 [ "identificador" => "bib0075" "etiqueta" => "15." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Low molecular weight heparin in acute coronary syndrome: evidence for superior or equivalent efficacy compared with unfractionated heparin?" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "S. Kaul" 1 => "P.K. Shah" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "J Am Coll Cardiol" "fecha" => "2000" "volumen" => "35" "paginaInicial" => "1699" "paginaFinal" => "1712" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/10841215" "web" => "Medline" ] ] ] ] ] ] ] ] 15 => array:3 [ "identificador" => "bib0080" "etiqueta" => "16." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Aspirin, heparin, or both to treat acute unstable angina" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "P. Théroux" 1 => "H. Ouimet" 2 => "J. McCans" 3 => "J.G. Latour" 4 => "P. Joly" 5 => "G. Lévy" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1056/NEJM198810273191701" "Revista" => array:6 [ "tituloSerie" => "N Engl J Med" "fecha" => "1988" "volumen" => "319" "paginaInicial" => "1105" "paginaFinal" => "1111" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/3050522" "web" => "Medline" ] ] ] ] ] ] ] ] 16 => array:3 [ "identificador" => "bib0085" "etiqueta" => "17." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Aspirin versus heparin to prevent myocardial infarction during the acute phase of unstable angina" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:6 [ 0 => "P. Théroux" 1 => "D. Waters" 2 => "S. Qiu" 3 => "J. McCans" 4 => "P. De Guise" 5 => "M. Juneau" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Circulation" "fecha" => "1993" "volumen" => "88" "paginaInicial" => "2045" "paginaFinal" => "2048" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/8222097" "web" => "Medline" ] ] ] ] ] ] ] ] 17 => array:3 [ "identificador" => "bib0090" "etiqueta" => "18." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:1 [ "titulo" => "The RISC Group. Risk of myocardial infarction and death during treatment with low dose aspirin and intravenous heparin in men with unstable coronary artery disease" ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Lancet" "fecha" => "1990" "volumen" => "336" "paginaInicial" => "827" "paginaFinal" => "830" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/1976875" "web" => "Medline" ] ] ] ] ] ] ] ] 18 => array:3 [ "identificador" => "bib0095" "etiqueta" => "19." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Combination antithrombin therapy in unstable rest angina and non-Q-wave infarction in nonprior aspirin users. Primary end points analysis from the ATACS trial" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "M. Cohen" 1 => "P. Adams" 2 => "G. Parry" 3 => "J. Xiong" 4 => "D. Chamberlain" 5 => "I. Wieczorek" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Circulation" "fecha" => "1994" "volumen" => "89" "paginaInicial" => "81" "paginaFinal" => "88" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/8281698" "web" => "Medline" ] ] ] ] ] ] ] ] 19 => array:3 [ "identificador" => "bib0100" "etiqueta" => "20." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Comparison of the effect of heparin and aspirin versus heparin alone on transient myocardial ischemia and in-hospital prognosis in patients with unstable angina" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "D. Holdright" 1 => "D. Patel" 2 => "D. Cunningham" 3 => "R. Thomas" 4 => "W. Hubbard" 5 => "G. Hendry" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "J Am Coll Cardiol" "fecha" => "1994" "volumen" => "24" "paginaInicial" => "39" "paginaFinal" => "45" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/8006281" "web" => "Medline" ] ] ] ] ] ] ] ] 20 => array:3 [ "identificador" => "bib0105" "etiqueta" => "21." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Long-term management. The way forward?" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "L. Wallentin" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Clin Cardiol" "fecha" => "2000" "volumen" => "23" "paginaInicial" => "13" "paginaFinal" => "17" ] ] ] ] ] ] 21 => array:3 [ "identificador" => "bib0110" "etiqueta" => "22." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Management of unstable coronary-artery disease" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "A.T. Cohen" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Lancet" "fecha" => "2000" "paginaInicial" => "355" "paginaFinal" => "574" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/89410" "web" => "Medline" ] ] ] ] ] ] ] ] ] ] ] ] ] "idiomaDefecto" => "es" "url" => "/00257753/0000011500000015/v1_201307291747/S0025775300716319/v1_201307291747/es/main.assets" "Apartado" => array:4 [ "identificador" => "64287" "tipo" => "SECCION" "es" => array:2 [ "titulo" => "Revisión" "idiomaDefecto" => true ] "idiomaDefecto" => "es" ] "PDF" => "https://static.elsevier.es/multimedia/00257753/0000011500000015/v1_201307291747/S0025775300716319/v1_201307291747/es/main.pdf?idApp=UINPBA00004N&text.app=https://www.elsevier.es/" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0025775300716319?idApp=UINPBA00004N" ]
| año/Mes | Html | Total | |
|---|---|---|---|
| 2024 Octubre | 0 | 2 | 2 |
| 2024 Septiembre | 0 | 2 | 2 |
| 2024 Agosto | 0 | 3 | 3 |
| 2024 Julio | 0 | 1 | 1 |
| 2024 Junio | 0 | 3 | 3 |
| 2024 Mayo | 0 | 4 | 4 |
| 2024 Abril | 0 | 14 | 14 |
| 2024 Marzo | 0 | 5 | 5 |
| 2024 Febrero | 0 | 6 | 6 |
| 2024 Enero | 0 | 5 | 5 |
| 2023 Diciembre | 0 | 11 | 11 |
| 2023 Noviembre | 0 | 6 | 6 |
| 2023 Octubre | 0 | 6 | 6 |
| 2023 Septiembre | 0 | 1 | 1 |
| 2023 Agosto | 0 | 2 | 2 |
| 2023 Julio | 0 | 13 | 13 |
| 2023 Junio | 0 | 6 | 6 |
| 2023 Mayo | 0 | 4 | 4 |
| 2023 Abril | 0 | 3 | 3 |
| 2023 Marzo | 1 | 2 | 3 |
| 2023 Febrero | 0 | 7 | 7 |
| 2023 Enero | 0 | 5 | 5 |
| 2022 Diciembre | 0 | 4 | 4 |
| 2022 Noviembre | 0 | 5 | 5 |
| 2022 Octubre | 0 | 3 | 3 |
| 2022 Septiembre | 0 | 5 | 5 |
| 2022 Julio | 0 | 3 | 3 |
| 2022 Junio | 0 | 6 | 6 |
| 2022 Mayo | 0 | 4 | 4 |
| 2022 Marzo | 0 | 9 | 9 |
| 2022 Enero | 0 | 2 | 2 |
| 2021 Diciembre | 0 | 2 | 2 |
| 2021 Noviembre | 0 | 2 | 2 |
| 2021 Octubre | 0 | 3 | 3 |
| 2021 Agosto | 0 | 1 | 1 |
| 2021 Julio | 0 | 5 | 5 |
| 2021 Junio | 0 | 1 | 1 |
| 2021 Mayo | 0 | 3 | 3 |
| 2021 Febrero | 0 | 7 | 7 |
| 2021 Enero | 0 | 2 | 2 |
| 2020 Diciembre | 0 | 4 | 4 |
| 2020 Agosto | 0 | 3 | 3 |
| 2020 Julio | 0 | 3 | 3 |
| 2020 Junio | 0 | 3 | 3 |
| 2020 Mayo | 0 | 3 | 3 |
| 2020 Abril | 0 | 1 | 1 |
| 2020 Marzo | 0 | 8 | 8 |
| 2020 Febrero | 0 | 3 | 3 |
| 2020 Enero | 0 | 2 | 2 |
| 2019 Diciembre | 0 | 9 | 9 |
| 2019 Octubre | 0 | 2 | 2 |
| 2019 Septiembre | 0 | 3 | 3 |
| 2019 Agosto | 0 | 4 | 4 |
| 2019 Julio | 0 | 6 | 6 |
| 2019 Junio | 0 | 4 | 4 |
| 2019 Mayo | 0 | 21 | 21 |
| 2017 Octubre | 3 | 0 | 3 |
| 2017 Septiembre | 8 | 8 | 16 |
| 2017 Agosto | 10 | 8 | 18 |
| 2017 Julio | 13 | 3 | 16 |
| 2017 Junio | 10 | 9 | 19 |
| 2017 Mayo | 10 | 7 | 17 |
| 2017 Abril | 5 | 1 | 6 |
| 2017 Marzo | 11 | 27 | 38 |
| 2017 Febrero | 13 | 3 | 16 |
| 2017 Enero | 8 | 0 | 8 |
| 2016 Diciembre | 16 | 5 | 21 |
| 2016 Noviembre | 17 | 3 | 20 |
| 2016 Octubre | 30 | 1 | 31 |
| 2016 Septiembre | 18 | 2 | 20 |
| 2016 Agosto | 8 | 1 | 9 |
| 2016 Julio | 6 | 1 | 7 |
| 2016 Junio | 27 | 2 | 29 |
| 2016 Mayo | 13 | 2 | 15 |
| 2016 Abril | 19 | 2 | 21 |
| 2016 Marzo | 14 | 0 | 14 |
| 2016 Febrero | 14 | 1 | 15 |
| 2016 Enero | 20 | 0 | 20 |
| 2015 Diciembre | 17 | 0 | 17 |
| 2015 Noviembre | 13 | 0 | 13 |
| 2015 Octubre | 27 | 0 | 27 |
| 2015 Septiembre | 18 | 0 | 18 |
| 2015 Agosto | 14 | 0 | 14 |
| 2015 Julio | 9 | 0 | 9 |
| 2015 Junio | 6 | 0 | 6 |
| 2015 Mayo | 4 | 0 | 4 |
| 2015 Abril | 12 | 0 | 12 |
| 2015 Marzo | 10 | 0 | 10 |
| 2015 Febrero | 11 | 0 | 11 |
| 2015 Enero | 15 | 0 | 15 |
| 2014 Diciembre | 18 | 0 | 18 |
| 2014 Noviembre | 5 | 0 | 5 |
| 2014 Octubre | 8 | 0 | 8 |
| 2014 Septiembre | 16 | 0 | 16 |
| 2014 Agosto | 6 | 0 | 6 |
| 2014 Julio | 7 | 0 | 7 |
| 2014 Junio | 9 | 0 | 9 |
| 2014 Mayo | 5 | 0 | 5 |
| 2014 Abril | 3 | 0 | 3 |
| 2014 Marzo | 1 | 0 | 1 |
| 2014 Febrero | 4 | 0 | 4 |
| 2014 Enero | 10 | 0 | 10 |
| 2013 Diciembre | 3 | 0 | 3 |
| 2013 Noviembre | 7 | 0 | 7 |
| 2013 Octubre | 8 | 0 | 8 |
| 2013 Septiembre | 4 | 0 | 4 |
| 2013 Agosto | 4 | 0 | 4 |
| 2013 Mayo | 1 | 0 | 1 |
| 2000 Noviembre | 654 | 0 | 654 |
Mostrar todo
