Asma relacionada con la inhalación de Plantago ovata
Asthma related to inhalation of Plantago ovata
Ana María Alemán, Santiago Quirce, Cristina Bombín, Joaquín Sastre
Fundación Jiménez Díaz. Servicio de Alergia. Universidad Autónoma de Madrid.
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"documento" => "simple-article" "crossmark" => 0 "subdocumento" => "edi" "cita" => "Med Clin. 2001;116:18-9" "abierto" => array:3 [ "ES" => false "ES2" => false "LATM" => false ] "gratuito" => false "lecturas" => array:2 [ "total" => 2170 "formatos" => array:3 [ "EPUB" => 5 "HTML" => 1677 "PDF" => 488 ] ] "es" => array:7 [ "idiomaDefecto" => true "titulo" => "Músculo y corazón" "tienePdf" => "es" "tieneTextoCompleto" => 0 "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "18" "paginaFinal" => "19" ] ] "contienePdf" => array:1 [ "es" => true ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "Pascual Barona Zamora" "autores" => array:1 [ 0 => array:2 [ "nombre" => "Pascual" "apellidos" => "Barona Zamora" ] ] ] ] ] "idiomaDefecto" => "es" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0025775301717046?idApp=UINPBA00004N" "url" => "/00257753/0000011600000001/v1_201307291411/S0025775301717046/v1_201307291411/es/main.assets" ] "es" => array:12 [ "idiomaDefecto" => true "titulo" => "Asma relacionada con la inhalación de Plantago ovata" "tieneTextoCompleto" => 0 "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "20" "paginaFinal" => "22" ] ] "autores" => array:1 [ 0 => array:3 [ "autoresLista" => "Ana María Alemán, Santiago Quirce, Cristina Bombín, Joaquín Sastre" "autores" => array:4 [ 0 => array:2 [ "nombre" => "Ana" "apellidos" => "María Alemán" ] 1 => array:2 [ "nombre" => "Santiago" "apellidos" => "Quirce" ] 2 => array:2 [ "nombre" => "Cristina" "apellidos" => "Bombín" ] 3 => array:2 [ "nombre" => "Joaquín" "apellidos" => "Sastre" ] ] "afiliaciones" => array:1 [ 0 => array:1 [ "entidad" => "<span class="elsevierStyleItalic">Fundación Jiménez Díaz. Servicio de Alergia. Universidad Autónoma de Madrid.</span>" ] ] ] ] "titulosAlternativos" => array:1 [ "en" => array:1 [ "titulo" => "Asthma related to inhalation of Plantago ovata" ] ] "pdfFichero" => "main.pdf" "tienePdf" => true "PalabrasClave" => array:2 [ "es" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Palabras Clave" "identificador" => "xpalclavsec220718" "palabras" => array:6 [ 0 => "Alergenos" 1 => "Hiperreactividad bronquial" 2 => "Laxantes" 3 => "<span class="elsevierStyleItalic">Psyllium</span>" 4 => "<span class="elsevierStyleItalic">Plantago ovata</span>" 5 => "Provocación bronquial específica" ] ] ] "en" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Keywords" "identificador" => "xpalclavsec220717" "palabras" => array:6 [ 0 => "Allergens" 1 => "Bronchial hyperresponsiveness" 2 => "Laxatives" 3 => "<span class="elsevierStyleItalic">Psyllium</span>" 4 => "<span class="elsevierStyleItalic">Plantago ovata</span>" 5 => "Bronchial challenge test" ] ] ] ] "tieneResumen" => true "resumen" => array:2 [ "es" => array:1 [ "resumen" => "<span class="elsevierStyleSectionTitle">Fundamentos</span><p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">El <span class="elsevierStyleItalic">psyllium</span>, obtenido de semillas de Plantago ovata, se utiliza como laxante de volumen. Se ha descrito que puede actuar como un alergeno por vía inhalatoria, fundamentalmente en el medio laboral. Presentamos un caso clínico de asma por semillas de P. ovata, destacando el potencial alergénico de esta sustancia de uso frecuente como laxante. Se trata de una paciente de 31 años de edad, fumadora y atópica, que desde hacía unos 3 años preparaba y administraba en su domicilio, a su madre incapacitada, dos sobres diarios de un laxante con semillas de P. ovata (Plantaben®).</p> <span class="elsevierStyleSectionTitle">Métodos Y Resultados</span><p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">Se realizaron pruebas cutáneas de hipersensibilidad inmediata (<span class="elsevierStyleItalic">prick</span> ) con un extracto de <span class="elsevierStyleItalic">psyllium</span>, resultando positivas. Se detectó IgE específica a P. ovata mediante técnica ELISA. El test de inhalación bronquial con metacolina reveló una hiperreactividad bronquial leve (PC20 = 1,5 mg/ml). En el test de provocación bronquial específico con <span class="elsevierStyleItalic">psyllium</span> se obtuvo una respuesta inmediata. Los alergenos responsables se identificaron mediante SDSPAGE e inmunoblot, observándose varios componentes alergénicos con pesos moleculares aparentes de 66 kDa, 60 kDa, entre 36-20 kDa y de 14 kDa. Se investigó si existía reactividad cruzada con el polen de <span class="elsevierStyleItalic">Plantago lanceolata</span>, lo que se descartó mediante ensayo de ELISA-inhibición.</p> <span class="elsevierStyleSectionTitle">Conclusiones</span><p id="spar0015" class="elsevierStyleSimplePara elsevierViewall">El <span class="elsevierStyleItalic">psyllium</span> puede actuar como un potente alergeno capaz de causar asma, no sólo en el medio laboral, sino también en ambiente doméstico a los propios consumidores del laxante o a los familiares que los dispensan.</p>" ] "en" => array:1 [ "resumen" => "<span class="elsevierStyleSectionTitle">Background</span><p id="spar0020" class="elsevierStyleSimplePara elsevierViewall">Psyllium is the seed of the plant Plantago ovata, which is widely used in nonprescription laxatives. It has been reported that psyllium powder may act as an inhalant allergen, especially in the workplace. A patient with asthma due to inhalation of P. ovata seed powder is described, being highlighted the allergenic potential of this substance frequently used as a laxative. We report a 31 year-old atopic woman, who handled and prepared at home, twice daily, a laxative containing P. ovata seeds (Plantaben®) prescribed to her paralytic mother.</p> <span class="elsevierStyleSectionTitle">Methods and Results</span><p id="spar0025" class="elsevierStyleSimplePara elsevierViewall">Skin prick test to <span class="elsevierStyleItalic">psyllium</span> powder extract was positive. Specific IgE antibodies to <span class="elsevierStyleItalic">psyllium</span> were positive as determined by ELISA. Methacholine inhalation test revealed mild bronchial hyperresponsiveness (PC20 = 1.5 mg/ml). Specific bronchial challenge to <span class="elsevierStyleItalic">psyllium</span> powder elicited an isolated early asthmatic response. The allergens in psyllium were investigated by SDS-PAGE and immunoblotting, being identified several allergenic components with an apparent molecular weight of 66, 60, 36-20 and 14 kDa. No cross-reactivity was found between P. ovata seed and P. lanceolata pollen, as determined by ELISA-inhibition.</p> <span class="elsevierStyleSectionTitle">Conclusion</span><p id="spar0030" class="elsevierStyleSimplePara elsevierViewall">Psyllium may act as a potent inhalant allergen capable of eliciting asthma symptoms, not only in an occupational context, but also in a domestic environment, affecting consumers of this laxative or relatives who handle it.</p>" ] ] "bibliografia" => array:2 [ "titulo" => "Referencias Bibliográficas" "seccion" => array:1 [ 0 => array:2 [ "identificador" => "bibs0005" "bibliografiaReferencia" => array:20 [ 0 => array:3 [ "identificador" => "bib1" "etiqueta" => "1." 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| año/Mes | Html | Total | |
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| 2024 Noviembre | 0 | 1 | 1 |
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| 2024 Septiembre | 0 | 8 | 8 |
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| 2024 Enero | 0 | 21 | 21 |
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| 2023 Noviembre | 0 | 7 | 7 |
| 2023 Octubre | 0 | 17 | 17 |
| 2023 Septiembre | 0 | 8 | 8 |
| 2023 Agosto | 0 | 15 | 15 |
| 2023 Julio | 0 | 29 | 29 |
| 2023 Junio | 0 | 14 | 14 |
| 2023 Mayo | 0 | 12 | 12 |
| 2023 Abril | 0 | 3 | 3 |
| 2023 Marzo | 1 | 11 | 12 |
| 2023 Febrero | 1 | 23 | 24 |
| 2023 Enero | 0 | 6 | 6 |
| 2022 Diciembre | 0 | 2 | 2 |
| 2022 Noviembre | 0 | 8 | 8 |
| 2022 Octubre | 0 | 9 | 9 |
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| 2022 Agosto | 0 | 12 | 12 |
| 2022 Julio | 0 | 6 | 6 |
| 2022 Junio | 0 | 4 | 4 |
| 2022 Mayo | 0 | 8 | 8 |
| 2022 Abril | 0 | 4 | 4 |
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| 2022 Febrero | 0 | 6 | 6 |
| 2022 Enero | 0 | 2 | 2 |
| 2021 Diciembre | 0 | 3 | 3 |
| 2021 Agosto | 0 | 1 | 1 |
| 2021 Junio | 0 | 1 | 1 |
| 2021 Marzo | 0 | 1 | 1 |
| 2021 Enero | 0 | 1 | 1 |
| 2020 Diciembre | 0 | 6 | 6 |
| 2020 Noviembre | 0 | 18 | 18 |
| 2020 Septiembre | 1 | 0 | 1 |
| 2020 Agosto | 0 | 6 | 6 |
| 2020 Junio | 0 | 1 | 1 |
| 2020 Mayo | 0 | 4 | 4 |
| 2020 Abril | 0 | 14 | 14 |
| 2020 Marzo | 0 | 17 | 17 |
| 2020 Febrero | 0 | 10 | 10 |
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| 2019 Octubre | 0 | 21 | 21 |
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| 2017 Septiembre | 4 | 9 | 13 |
| 2017 Agosto | 10 | 6 | 16 |
| 2017 Julio | 12 | 2 | 14 |
| 2017 Junio | 20 | 26 | 46 |
| 2017 Mayo | 17 | 6 | 23 |
| 2017 Abril | 8 | 8 | 16 |
| 2017 Marzo | 9 | 20 | 29 |
| 2017 Febrero | 14 | 7 | 21 |
| 2017 Enero | 14 | 7 | 21 |
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| 2016 Noviembre | 52 | 14 | 66 |
| 2016 Octubre | 46 | 13 | 59 |
| 2016 Septiembre | 48 | 15 | 63 |
| 2016 Agosto | 17 | 21 | 38 |
| 2016 Julio | 26 | 9 | 35 |
| 2016 Junio | 35 | 16 | 51 |
| 2016 Mayo | 27 | 15 | 42 |
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| 2016 Marzo | 15 | 25 | 40 |
| 2016 Febrero | 23 | 16 | 39 |
| 2016 Enero | 27 | 16 | 43 |
| 2015 Diciembre | 19 | 10 | 29 |
| 2015 Noviembre | 21 | 14 | 35 |
| 2015 Octubre | 24 | 23 | 47 |
| 2015 Septiembre | 25 | 13 | 38 |
| 2015 Agosto | 14 | 7 | 21 |
| 2015 Julio | 16 | 8 | 24 |
| 2015 Junio | 16 | 8 | 24 |
| 2015 Mayo | 14 | 12 | 26 |
| 2015 Abril | 11 | 15 | 26 |
| 2015 Marzo | 24 | 8 | 32 |
| 2015 Febrero | 20 | 9 | 29 |
| 2015 Enero | 13 | 2 | 15 |
| 2014 Diciembre | 21 | 2 | 23 |
| 2014 Noviembre | 8 | 0 | 8 |
| 2014 Octubre | 9 | 0 | 9 |
| 2014 Septiembre | 12 | 1 | 13 |
| 2014 Agosto | 15 | 1 | 16 |
| 2014 Julio | 13 | 0 | 13 |
| 2014 Junio | 12 | 0 | 12 |
| 2014 Mayo | 7 | 2 | 9 |
| 2014 Abril | 7 | 1 | 8 |
| 2014 Marzo | 6 | 0 | 6 |
| 2014 Febrero | 8 | 0 | 8 |
| 2014 Enero | 5 | 3 | 8 |
| 2013 Diciembre | 7 | 2 | 9 |
| 2013 Noviembre | 3 | 1 | 4 |
| 2013 Octubre | 10 | 4 | 14 |
| 2013 Septiembre | 12 | 5 | 17 |
| 2013 Agosto | 10 | 7 | 17 |
| 2013 Julio | 6 | 0 | 6 |
| 2013 Junio | 2 | 0 | 2 |
| 2013 Mayo | 1 | 0 | 1 |
| 2001 Enero | 929 | 0 | 929 |
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