metricas
covid
Buscar en
Medicina Clínica
Toda la web
Inicio Medicina Clínica Síndrome de hipersensibilidad por antiepilépticos
Información de la revista

Estadísticas

Siga este enlace para acceder al texto completo del artículo

Preguntas y respuestas en farmacología clínica
Síndrome de hipersensibilidad por antiepilépticos
Marta Durán, Imma Danés*
Fundació Institut Català de Farmacologia. Servei de Farmacologia Clínica. Hospitals Vall d’Hebron. Barcelona.
Leído
2659
Veces
se ha leído el artículo
1061
Total PDF
1598
Total HTML
Compartir estadísticas
 array:23 [
  "pii" => "S002577530171754X"
  "issn" => "00257753"
  "doi" => "10.1016/S0025-7753(01)71754-X"
  "estado" => "S300"
  "fechaPublicacion" => "2001-01-01"
  "aid" => "71754"
  "copyright" => "Elsevier España, S.L.. Todos los derechos reservados"
  "copyrightAnyo" => "2001"
  "documento" => "simple-article"
  "crossmark" => 0
  "subdocumento" => "exm"
  "cita" => "Med Clin. 2001;116:155-6"
  "abierto" => array:3 [
    "ES" => false
    "ES2" => false
    "LATM" => false
  ]
  "gratuito" => false
  "lecturas" => array:2 [
    "total" => 1883
    "formatos" => array:3 [
      "EPUB" => 6
      "HTML" => 1597
      "PDF" => 280
    ]
  ]
  "itemSiguiente" => array:18 [
    "pii" => "S0025775301717551"
    "issn" => "00257753"
    "doi" => "10.1016/S0025-7753(01)71755-1"
    "estado" => "S300"
    "fechaPublicacion" => "2001-01-01"
    "aid" => "71755"
    "copyright" => "Elsevier España, S.L."
    "documento" => "simple-article"
    "crossmark" => 0
    "subdocumento" => "cor"
    "cita" => "Med Clin. 2001;116:157"
    "abierto" => array:3 [
      "ES" => false
      "ES2" => false
      "LATM" => false
    ]
    "gratuito" => false
    "lecturas" => array:2 [
      "total" => 1299
      "formatos" => array:3 [
        "EPUB" => 8
        "HTML" => 1111
        "PDF" => 180
      ]
    ]
    "es" => array:8 [
      "idiomaDefecto" => true
      "cabecera" => "<span class="elsevierStyleTextfn">Cartas Al Editor</span>"
      "titulo" => "Influencia de un mercado ambulante sobre las visitas a un servicio de urgencias hospitalario"
      "tienePdf" => "es"
      "tieneTextoCompleto" => 0
      "paginas" => array:1 [
        0 => array:1 [
          "paginaInicial" => "157"
        ]
      ]
      "contienePdf" => array:1 [
        "es" => true
      ]
      "autores" => array:1 [
        0 => array:2 [
          "autoresLista" => "Jos&#233; Luis Zambrana Garc&#237;a, Emilio del Campo Molina, Francisco Fuentes Jim&#233;nez, Miguel &#193;ngel Fern&#225;ndez Sacrist&#225;n"
          "autores" => array:4 [
            0 => array:2 [
              "nombre" => "Jos&#233;"
              "apellidos" => "Luis Zambrana Garc&#237;a"
            ]
            1 => array:2 [
              "nombre" => "Emilio"
              "apellidos" => "del Campo Molina"
            ]
            2 => array:2 [
              "nombre" => "Francisco"
              "apellidos" => "Fuentes Jim&#233;nez"
            ]
            3 => array:2 [
              "nombre" => "Miguel"
              "apellidos" => "&#193;ngel Fern&#225;ndez Sacrist&#225;n"
            ]
          ]
        ]
      ]
    ]
    "idiomaDefecto" => "es"
    "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0025775301717551?idApp=UINPBA00004N"
    "url" => "/00257753/0000011600000004/v1_201307291415/S0025775301717551/v1_201307291415/es/main.assets"
  ]
  "itemAnterior" => array:18 [
    "pii" => "S0025775301717538"
    "issn" => "00257753"
    "doi" => "10.1016/S0025-7753(01)71753-8"
    "estado" => "S300"
    "fechaPublicacion" => "2001-01-01"
    "aid" => "71753"
    "copyright" => "Elsevier Espa&#241;a&#44; S&#46;L&#46;"
    "documento" => "article"
    "crossmark" => 0
    "subdocumento" => "rev"
    "cita" => "Med Clin. 2001;116:150-4"
    "abierto" => array:3 [
      "ES" => false
      "ES2" => false
      "LATM" => false
    ]
    "gratuito" => false
    "lecturas" => array:2 [
      "total" => 1503
      "formatos" => array:3 [
        "EPUB" => 5
        "HTML" => 1241
        "PDF" => 257
      ]
    ]
    "es" => array:8 [
      "idiomaDefecto" => true
      "cabecera" => "<span class="elsevierStyleTextfn">Revisi&#243;n</span>"
      "titulo" => "Efectividad de los programas de mantenimiento con metadona&#46; Una revisi&#243;n de los resultados de los estudios de evaluaci&#243;n"
      "tienePdf" => "es"
      "tieneTextoCompleto" => 0
      "paginas" => array:1 [
        0 => array:2 [
          "paginaInicial" => "150"
          "paginaFinal" => "154"
        ]
      ]
      "contienePdf" => array:1 [
        "es" => true
      ]
      "autores" => array:1 [
        0 => array:2 [
          "autoresLista" => "Juan Jos&#233; Fern&#225;ndez Miranda"
          "autores" => array:1 [
            0 => array:2 [
              "nombre" => "Juan"
              "apellidos" => "Jos&#233; Fern&#225;ndez Miranda"
            ]
          ]
        ]
      ]
    ]
    "idiomaDefecto" => "es"
    "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0025775301717538?idApp=UINPBA00004N"
    "url" => "/00257753/0000011600000004/v1_201307291415/S0025775301717538/v1_201307291415/es/main.assets"
  ]
  "es" => array:11 [
    "idiomaDefecto" => true
    "cabecera" => "<span class="elsevierStyleTextfn">Preguntas y respuestas en farmacolog&#237;a cl&#237;nica</span>"
    "titulo" => "S&#237;ndrome de hipersensibilidad por antiepil&#233;pticos"
    "tieneTextoCompleto" => 0
    "paginas" => array:1 [
      0 => array:2 [
        "paginaInicial" => "155"
        "paginaFinal" => "156"
      ]
    ]
    "autores" => array:1 [
      0 => array:4 [
        "autoresLista" => "Marta Dur&#225;n, Imma Dan&#233;s"
        "autores" => array:2 [
          0 => array:2 [
            "nombre" => "Marta"
            "apellidos" => "Dur&#225;n"
          ]
          1 => array:3 [
            "nombre" => "Imma"
            "apellidos" => "Dan&#233;s"
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">&#42;</span>"
                "identificador" => "cor0005"
              ]
            ]
          ]
        ]
        "afiliaciones" => array:1 [
          0 => array:1 [
            "entidad" => "Fundaci&#243; Institut Catal&#224; de Farmacologia&#46; Servei de Farmacologia Cl&#237;nica&#46; Hospitals Vall d&#8217;Hebron&#46; Barcelona&#46;"
          ]
        ]
        "correspondencia" => array:1 [
          0 => array:3 [
            "identificador" => "cor0005"
            "etiqueta" => "&#42;"
            "correspondencia" => "Correspondence&#58; Fundaci&#243; Institut Catal&#224; de Farmacologia&#46; Hospitals Vall d&#39;Hebron&#46; Passeig Vall d&#39;Hebron&#44; 119-129&#46; 08035 Barcelona&#46;"
          ]
        ]
      ]
    ]
    "pdfFichero" => "main.pdf"
    "tienePdf" => true
    "fechaRecibido" => "2000-07-03"
    "fechaAceptado" => "2000-12-12"
    "bibliografia" => array:2 [
      "titulo" => "Referencias Bibliogr&#225;ficas"
      "seccion" => array:1 [
        0 => array:2 [
          "identificador" => "bibs0005"
          "bibliografiaReferencia" => array:19 [
            0 => array:3 [
              "identificador" => "bib0005"
              "etiqueta" => "1&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Antiepileptic drug hypersensitivity syndrome"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "R&#46;G&#46; Schlienger"
                            1 => "N&#46;H&#46; Shear"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Epilepsia"
                        "fecha" => "1998"
                        "volumen" => "39"
                        "numero" => "Supl 7"
                        "paginaInicial" => "3"
                        "paginaFinal" => "7"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            1 => array:3 [
              "identificador" => "bib0010"
              "etiqueta" => "2&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Risk of serious cutaneous disorders after initiation of use of phenytoin carbamazepine&#44; or sodium valproate&#46; A record-linkage study"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "P&#46; Tennis"
                            1 => "R&#46;S&#46; Stern"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Neurology"
                        "fecha" => "1997"
                        "volumen" => "49"
                        "paginaInicial" => "542"
                        "paginaFinal" => "546"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/9270593"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            2 => array:3 [
              "identificador" => "bib0015"
              "etiqueta" => "3&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Anticonvulsant hypersensitivity syndrome"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "C&#46;C&#46; Vittorio"
                            1 => "J&#46;J&#46; Muglia"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Arch Intern Med"
                        "fecha" => "1995"
                        "volumen" => "155"
                        "paginaInicial" => "2285"
                        "paginaFinal" => "2290"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/7487252"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            3 => array:3 [
              "identificador" => "bib0020"
              "etiqueta" => "4&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Anticonvulsant hypersensitivity syndrome&#46; Incidence&#44; prevention and management"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "R&#46;K&#46; Knowles"
                            1 => "L&#46;E&#46; Shapiro"
                            2 => "N&#46;H&#46; Shear"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Drug Safety"
                        "fecha" => "1999"
                        "volumen" => "21"
                        "paginaInicial" => "489"
                        "paginaFinal" => "501"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/10612272"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            4 => array:3 [
              "identificador" => "bib0025"
              "etiqueta" => "5&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Lamotrigine-associated rash&#58; risk&#47;benefit considerations in adults and children"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "A&#46;H&#46; Guberman"
                            1 => "F&#46;M&#46;C&#46; Besag"
                            2 => "M&#46;J&#46; Brodie"
                            3 => "J&#46;M&#46; Dooley"
                            4 => "M&#46;S&#46; Duchowny"
                            5 => "J&#46;M&#46; Pellock"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Epilepsia"
                        "fecha" => "1999"
                        "volumen" => "40"
                        "paginaInicial" => "985"
                        "paginaFinal" => "991"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/10403224"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            5 => array:3 [
              "identificador" => "bib0030"
              "etiqueta" => "6&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Adding lamotrigine to valproate&#58; incidence of rash and other adverse effects"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "E&#46; Faught"
                            1 => "G&#46; Morris"
                            2 => "M&#46; Jacobson"
                            3 => "J&#46; French"
                            4 => "C&#46; Harden"
                            5 => "G&#46; Montouris"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Epilepsia"
                        "fecha" => "1999"
                        "volumen" => "40"
                        "paginaInicial" => "1135"
                        "paginaFinal" => "1140"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/10448828"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            6 => array:3 [
              "identificador" => "bib0035"
              "etiqueta" => "7&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Mechanisms of idiosyncratic hypersensitivity reactions to antiepileptics drugs"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:1 [
                            0 => "J&#46;S&#46; Leeder"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Epilepsia"
                        "fecha" => "1998"
                        "volumen" => "39"
                        "numero" => "Supl 7"
                        "paginaInicial" => "8"
                        "paginaFinal" => "16"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            7 => array:3 [
              "identificador" => "bib0040"
              "etiqueta" => "8&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Antiepileptic drug pharmacogenetics"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:1 [
                            0 => "P&#46;N&#46; Patsalos"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Ther Drug Monit"
                        "fecha" => "2000"
                        "volumen" => "22"
                        "paginaInicial" => "127"
                        "paginaFinal" => "130"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/10688275"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            8 => array:3 [
              "identificador" => "bib0045"
              "etiqueta" => "9&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Anticonvulsant hypersensitivity syndrome&#58; in vitro assessment of risk"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "N&#46;H&#46; Shear"
                            1 => "S&#46;P&#46; Spielberg"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1172/JCI113798"
                      "Revista" => array:6 [
                        "tituloSerie" => "J Clin Invest"
                        "fecha" => "1988"
                        "volumen" => "82"
                        "paginaInicial" => "1826"
                        "paginaFinal" => "1832"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/3198757"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            9 => array:3 [
              "identificador" => "bib0050"
              "etiqueta" => "10&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Syndrome d&#8217;hypersensibilit&#233; medicamentose au cours d&#8217;un traitement par acide valpro&#239;que"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:6 [
                            0 => "P&#46; Platin"
                            1 => "H&#46; Cartier"
                            2 => "G&#46; Bihan"
                            3 => "P&#46; Clovard"
                            4 => "F&#46; Lelluche"
                            5 => "J&#46;P&#46; Leroy"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Presse Med"
                        "fecha" => "1995"
                        "volumen" => "24"
                        "paginaInicial" => "1624"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/8545377"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            10 => array:3 [
              "identificador" => "bib0055"
              "etiqueta" => "11&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Drug hypersensitivity syndrome to valproic acid"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:4 [
                            0 => "N&#46; Picart"
                            1 => "B&#46; Periole"
                            2 => "J&#46; Mazereeuw"
                            3 => "J&#46;L&#46; Bonafe"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Presse Med"
                        "fecha" => "2000"
                        "volumen" => "29"
                        "paginaInicial" => "648"
                        "paginaFinal" => "650"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/10780197"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            11 => array:3 [
              "identificador" => "bib0060"
              "etiqueta" => "12&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Multisystem hypersensitivity reaction to lamotrigine"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "B&#46;M&#46; Sarris"
                            1 => "J&#46;G&#46; Wong"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Neurology"
                        "fecha" => "1999"
                        "volumen" => "53"
                        "paginaInicial" => "1367"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/10522909"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            12 => array:3 [
              "identificador" => "bib0065"
              "etiqueta" => "13&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Lamotrigine overdose presenting as anticonvulsant hypersensitivity syndrome"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:4 [
                            0 => "E&#46; Mylonakis"
                            1 => "C&#46;C&#46; Vittorio"
                            2 => "D&#46;A&#46; Hollik"
                            3 => "S&#46; Rounds"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Ann Pharmacother"
                        "fecha" => "1999"
                        "volumen" => "33"
                        "paginaInicial" => "557"
                        "paginaFinal" => "559"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/10369617"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            13 => array:3 [
              "identificador" => "bib0070"
              "etiqueta" => "14&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Lamotrigine-associated anticonvulsant hypersensitivity syndrome"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "R&#46;G&#46; Schlienger"
                            1 => "S&#46;R&#46; Knowles"
                            2 => "N&#46;H&#46; Shear"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Neurology"
                        "fecha" => "1998"
                        "volumen" => "51"
                        "paginaInicial" => "1172"
                        "paginaFinal" => "1175"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/9781550"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            14 => array:3 [
              "identificador" => "bib0075"
              "etiqueta" => "15&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "The new anticonvulsants drugs&#46; Implications for avoidance of adverse effects"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "D&#46; Schmidt"
                            1 => "G&#46; Kr&#228;mer"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Drug Safety"
                        "fecha" => "1994"
                        "volumen" => "11"
                        "paginaInicial" => "422"
                        "paginaFinal" => "431"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/7727052"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            15 => array:3 [
              "identificador" => "bib0080"
              "etiqueta" => "16&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Stevens-Johnson syndrome associated with gabapentin"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:4 [
                            0 => "L&#46; Gonz&#225;lez-Sicilia"
                            1 => "A&#46; Cano"
                            2 => "M&#46; Serrano"
                            3 => "J&#46; Hern&#225;ndez"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Am J Med"
                        "fecha" => "1998"
                        "volumen" => "105"
                        "paginaInicial" => "455"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/9831434"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            16 => array:3 [
              "identificador" => "bib0085"
              "etiqueta" => "17&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Skin eruption with gabapentin in a patient with repeated AED-induced Stevens-Johnson&#8217;s syndrome"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:4 [
                            0 => "J&#46;C&#46; De Toledo"
                            1 => "A&#46; Minigar"
                            2 => "M&#46;R&#46; Lowe"
                            3 => "R&#46;E&#46; Ramsay"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Ther Drug Monit"
                        "fecha" => "1999"
                        "volumen" => "21"
                        "paginaInicial" => "137"
                        "paginaFinal" => "138"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/10051068"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            17 => array:3 [
              "identificador" => "bib0090"
              "etiqueta" => "18&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Successful treatment with gabapentin in the presence of hypersensitivity syndrome to phenytoin and carbamazepine&#58; a rerport of three cases"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "H&#46;M&#46; Hamer"
                            1 => "H&#46;H&#46; Morris"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1053/seiz.1998.0268"
                      "Revista" => array:6 [
                        "tituloSerie" => "Seizure"
                        "fecha" => "1999"
                        "volumen" => "8"
                        "paginaInicial" => "190"
                        "paginaFinal" => "192"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/10356381"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            18 => array:3 [
              "identificador" => "bib0095"
              "etiqueta" => "19&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Tiagabine&#58; a novel antiepileptic drug"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "M&#46;S&#46; Luer"
                            1 => "D&#46;H&#46; Rhoney"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Ann Pharmacother"
                        "fecha" => "1998"
                        "volumen" => "32"
                        "paginaInicial" => "1173"
                        "paginaFinal" => "1180"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/9825084"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
          ]
        ]
      ]
    ]
  ]
  "idiomaDefecto" => "es"
  "url" => "/00257753/0000011600000004/v1_201307291415/S002577530171754X/v1_201307291415/es/main.assets"
  "Apartado" => array:4 [
    "identificador" => "16753"
    "tipo" => "SECCION"
    "es" => array:2 [
      "titulo" => "Preguntas y respuestas en farmacolog&#237;a cl&#237;nica"
      "idiomaDefecto" => true
    ]
    "idiomaDefecto" => "es"
  ]
  "PDF" => "https://static.elsevier.es/multimedia/00257753/0000011600000004/v1_201307291415/S002577530171754X/v1_201307291415/es/main.pdf?idApp=UINPBA00004N&text.app=https://www.elsevier.es/"
  "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S002577530171754X?idApp=UINPBA00004N"
]
Información del artículo
ISSN: 00257753
Idioma original: Español
Datos actualizados diariamente
año/Mes Html Pdf Total
2024 Noviembre 0 4 4
2024 Octubre 0 27 27
2024 Septiembre 0 24 24
2024 Agosto 0 26 26
2024 Julio 0 14 14
2024 Junio 0 22 22
2024 Mayo 0 15 15
2024 Abril 0 20 20
2024 Marzo 0 39 39
2024 Febrero 0 38 38
2024 Enero 0 44 44
2023 Diciembre 0 35 35
2023 Noviembre 0 54 54
2023 Octubre 0 49 49
2023 Septiembre 0 24 24
2023 Agosto 0 8 8
2023 Julio 0 28 28
2023 Junio 0 32 32
2023 Mayo 0 28 28
2023 Abril 0 18 18
2023 Marzo 1 16 17
2023 Febrero 0 20 20
2023 Enero 0 23 23
2022 Diciembre 0 18 18
2022 Noviembre 0 12 12
2022 Octubre 0 11 11
2022 Septiembre 0 3 3
2022 Agosto 0 5 5
2022 Julio 0 1 1
2022 Junio 0 9 9
2022 Mayo 0 1 1
2022 Abril 0 2 2
2022 Marzo 0 7 7
2022 Febrero 0 1 1
2022 Enero 0 4 4
2021 Diciembre 0 5 5
2021 Noviembre 0 2 2
2021 Octubre 0 10 10
2021 Septiembre 0 1 1
2021 Agosto 0 3 3
2021 Julio 0 7 7
2021 Junio 0 1 1
2021 Mayo 0 3 3
2021 Abril 0 4 4
2021 Marzo 0 5 5
2021 Febrero 0 8 8
2021 Enero 0 4 4
2020 Noviembre 0 5 5
2020 Octubre 0 3 3
2020 Septiembre 0 2 2
2020 Agosto 0 9 9
2020 Julio 0 2 2
2020 Junio 0 7 7
2020 Mayo 0 4 4
2020 Marzo 0 7 7
2020 Febrero 0 15 15
2020 Enero 0 20 20
2019 Diciembre 0 7 7
2019 Octubre 0 1 1
2019 Septiembre 0 5 5
2019 Julio 0 7 7
2019 Junio 0 1 1
2019 Mayo 0 29 29
2018 Mayo 0 1 1
2017 Octubre 2 2 4
2017 Septiembre 7 5 12
2017 Agosto 12 1 13
2017 Julio 6 1 7
2017 Junio 8 15 23
2017 Mayo 18 8 26
2017 Abril 13 0 13
2017 Marzo 20 40 60
2017 Febrero 20 5 25
2017 Enero 9 1 10
2016 Diciembre 24 3 27
2016 Noviembre 22 2 24
2016 Octubre 55 2 57
2016 Septiembre 34 4 38
2016 Agosto 15 7 22
2016 Julio 13 1 14
2016 Junio 24 9 33
2016 Mayo 18 3 21
2016 Abril 20 5 25
2016 Marzo 14 5 19
2016 Febrero 15 7 22
2016 Enero 17 8 25
2015 Diciembre 14 8 22
2015 Noviembre 15 3 18
2015 Octubre 18 3 21
2015 Septiembre 21 3 24
2015 Agosto 8 2 10
2015 Julio 10 4 14
2015 Junio 8 4 12
2015 Mayo 13 2 15
2015 Abril 12 7 19
2015 Marzo 11 2 13
2015 Febrero 6 0 6
2015 Enero 10 2 12
2014 Diciembre 16 1 17
2014 Noviembre 12 1 13
2014 Octubre 12 1 13
2014 Septiembre 9 0 9
2014 Agosto 6 0 6
2014 Julio 11 0 11
2014 Junio 11 0 11
2014 Mayo 8 1 9
2014 Abril 13 2 15
2014 Marzo 5 0 5
2014 Febrero 8 2 10
2014 Enero 3 3 6
2013 Diciembre 5 4 9
2013 Noviembre 5 1 6
2013 Octubre 5 3 8
2013 Septiembre 16 6 22
2013 Agosto 15 2 17
2013 Julio 4 0 4
2013 Mayo 1 0 1
2001 Febrero 900 0 900
Mostrar todo

Siga este enlace para acceder al texto completo del artículo

es en pt

¿Es usted profesional sanitario apto para prescribir o dispensar medicamentos?

Are you a health professional able to prescribe or dispense drugs?

Você é um profissional de saúde habilitado a prescrever ou dispensar medicamentos