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Lupus neonatal
Neonatal lupus
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ingresa por hipertransaminasemia y lesiones cutáneas. Nacido a término de embarazo y parto normales, destacaba la existencia de maculopápulas eritematosas, anulares, policíclicas, confluentes, con descamación fina en el borde interno, de 1<span class="elsevierStyleHsp" style=""></span>cm de diámetro, en superficie anterior del tronco y regiones parietotemporales (<a class="elsevierStyleCrossRef" href="#fig0005">fig. 1</a>). Analíticamente se objetivó GOT 181<span class="elsevierStyleHsp" style=""></span>U/l, GPT 135<span class="elsevierStyleHsp" style=""></span>U/l y GGT 259<span class="elsevierStyleHsp" style=""></span>U/l, linfocitosis relativa, VSG 40<span class="elsevierStyleHsp" style=""></span>mm, e IgE total y específica a alimentos normal, serología a virus hepatotropos negativa. El perfil de autoinmunidad demostró ANA positivo a título 1/320 con anti-dsDNA negativo, anti SSA/Ro 9<span class="elsevierStyleHsp" style=""></span>U/ml (positivo ><span class="elsevierStyleHsp" style=""></span>20<span class="elsevierStyleHsp" style=""></span>U/ml) y anti-SSB/La 111<span class="elsevierStyleHsp" style=""></span>U/ml (positivo ><span class="elsevierStyleHsp" style=""></span>20<span class="elsevierStyleHsp" style=""></span>U/ml). Se realizó estudio de autoinmunidad a la madre, previamente sana, que demostró anti-SSA/Ro 43<span class="elsevierStyleHsp" style=""></span>U/ml y anti-SSB/La 111<span class="elsevierStyleHsp" style=""></span>U/ml. Diagnosticado de lupus neonatal con afectación cutánea y hepática, presentó buena evolución, con normalización analítica y resolución de las lesiones.</p><elsevierMultimedia ident="fig0005"></elsevierMultimedia></span>" "pdfFichero" => "main.pdf" "tienePdf" => true "multimedia" => array:1 [ 0 => array:6 [ "identificador" => "fig0005" "etiqueta" => "Figura 1" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr1.jpeg" "Alto" => 979 "Ancho" => 1667 "Tamanyo" => 144611 ] ] ] ] ] "idiomaDefecto" => "es" "url" => "/00257753/0000014600000004/v2_201604080826/S0025775315003644/v2_201604080826/es/main.assets" "Apartado" => array:4 [ "identificador" => "64289" "tipo" => "SECCION" "es" => array:2 [ "titulo" => "Imágenes médicas" "idiomaDefecto" => true ] "idiomaDefecto" => "es" ] "PDF" => "https://static.elsevier.es/multimedia/00257753/0000014600000004/v2_201604080826/S0025775315003644/v2_201604080826/es/main.pdf?idApp=UINPBA00004N&text.app=https://www.elsevier.es/" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0025775315003644?idApp=UINPBA00004N" ]
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