Información del artículo
Resumen
La osteoporosis se define como una enfermedad que afecta el sistema músculoesquelético y se caracteriza por disminución en la masa mineral ósea con deterioro de la microarquitectura del tejido óseo que predispone a fracturas como principal complicación.
El alendronato es usado como terapia para el tratamiento de la osteoporosis. Uno de sus efectos adversos es la sobresupresión de los osteoclastos con el riesgo potencial de causar fracturas por estrés.
Se presenta un caso de una fractura femoral atraumática en una mujer de 42 años en terapia con alendronato durante seis años.
Palabras clave:
alendronato
osteoporosis
fractura espontánea
Summary
Osteoporosis is a disease that affects the skeleton and it is characterized by low bone mass and micro-structural deterioration of bone architecture, leading to an increased susceptibility to fracture as the main complication.
Alendronate is used as treatment for osteoporosis. One of the side-effects is the over-suppression of osteoclasts with the potential risk of stress fractures.
We present a case of atraumatic femoral fracture in a 42 year-old woman on alendronate therapy during six years.
Key words:
alendronate
osteoporosis
spontaneous fracture
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