Positron emission tomography/computed tomography (PET/CT) with 2-deoxy-2-[18F]-fluoro-D-glucose ( 18FDG) in a patient with cutaneous T-cell lymphoma

CASE REPORT

A 65-year-old man with a history of lymphoma was referred for a positron emission tomography/ computed tomography (PET/CT) with 2-deoxy-2-[¹⁸F]-fluoro-D-glucose F-(¹⁸FDG) study to evaluate a collection in the subcutaneous fat of the anterolateral upper abdomen reported on a CT scan. PET/CT scan (fig. 1) revealed mildly increased tracer activity localizing to multifocal discrete areas of haziness and infiltration in the subcutaneous tissues of the abdomen. Subsequent skin biopsy demonstrated subcutaneous panniculitis-like T-cell lymphoma.

Fig. 1.--Transaxial (A) positron emission tomography (PET) (B) computed tomography (CT) and (C) PET/CT fused images (LSO Biograph PET/CT scanner) at 70 minutes post injection of 16.5 mCi of ¹⁸F-FDG, demonstrating increased FDG uptake in multiple ill-defined subcutaneous nodules in the abdominal wall, with a maximum standardized uptake value (SUVmax) of 1.2 over the left anterolateral abdominal wall.

Cutaneous T-cell lymphoma (CTCL) is a rare disease, characterized by indolent patches and plaques in early stages, and extracutaneous involvement in advanced stages. Mycosis fungoides is the most common type of CTCL¹.

¹⁸F-FDG PET/CT scan might add valuable clinical information and guide biopsy of lesions with the highest SUV, thus facilitating patient management and follow up^1-3.

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Correspondencia:

S. Mahmood.

Department of Nuclear Medicine.

Montefiore Medical Center / Albert Einstein College of Medicine.

1695 A Eastchester Road.

Bronx, NY 10461.

E-mail: [e-mail]