Recomendaciones para la nomenclatura de compuestos radiomarcados

Peñuelas, I.; Lima, A.; Mitjavila, M.
doi:10.1016/j.remn.2019.10.004
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editores&#44; IUPAC&#44; farmacopeas&#8230;&#41;&#46;</p></li></ul></p><p id="par0030" class="elsevierStylePara elsevierViewall">Recientemente&#44; se ha publicado un resumen de dichas gu&#237;as<a class="elsevierStyleCrossRef" href="#bib0020"><span class="elsevierStyleSup">2</span></a> con la intenci&#243;n de facilitar su difusi&#243;n e intentar que las normas referidas se incluyan entre las instrucciones para los autores en las diferentes revistas que publican de manera habitual art&#237;culos que contienen t&#233;rminos radiofarmac&#233;uticos y&#47;o nombres de compuestos radioqu&#237;micos y radiof&#225;rmacos&#46;</p><p id="par0035" class="elsevierStylePara elsevierViewall">En este sentido&#44; la Revista Espa&#241;ola de Medicina Nuclear e Imagen Molecular &#40;REMNIM&#41; quiere hacerse eco de la conveniencia de que los autores de los manuscritos remitidos a la revista para su consideraci&#243;n tengan en cuenta dichas normas&#46; De este modo se pretende estandarizar los t&#233;rminos empleados&#44; as&#237; como intentar crear un estado de opini&#243;n que vaya paulatinamente descartando los t&#233;rminos inapropiados que se han venido utilizando con frecuencia en nuestro &#225;mbito de trabajo&#46;</p><p id="par0040" class="elsevierStylePara elsevierViewall">Si el s&#237;mbolo de un elemento en una f&#243;rmula qu&#237;mica &#40;junto con su n&#250;mero m&#225;sico&#44; p&#46;<span class="elsevierStyleHsp" style=""></span>ej&#46;&#44; <span class="elsevierStyleSup">99m</span>Tc&#41; o en combinaci&#243;n con el nombre de un compuesto qu&#237;mico se escribe sin corchetes&#44; indica que todas las mol&#233;culas del compuesto contienen el &#40;radio&#41;nucleido referido&#46; Este hecho es extremadamente raro en la pr&#225;ctica&#44; y se considera el caso frecuente de los radiof&#225;rmacos tecneciados&#44; en ellos siempre existe una fracci&#243;n de mol&#233;culas marcadas con tecnecio-99 y no con tecnecio-99m&#46;</p><p id="par0045" class="elsevierStylePara elsevierViewall">En consecuencia&#44; para indicar el enriquecimiento de un compuesto con un is&#243;topo &#40;sea este radiactivo o no&#41; debe indicarse el s&#237;mbolo del elemento junto con su n&#250;mero m&#225;sico como super&#237;ndice y escrito entre corchetes&#44; &#91;<span class="elsevierStyleSup">99m</span>Tc&#93; precediendo inmediatamente al nombre del compuesto o su f&#243;rmula&#44; sin espacio entre ellos &#40;p&#46;<span class="elsevierStyleHsp" style=""></span>ej&#46;&#44; &#91;<span class="elsevierStyleSup">18</span>O&#93;H<span class="elsevierStyleInf">2</span>O&#44; &#91;<span class="elsevierStyleSup">131</span>I&#93;NaI&#44; &#91;<span class="elsevierStyleSup">99m</span>Tc&#93;pertecnetato de sodio&#8230;&#41;&#46;</p><p id="par0050" class="elsevierStylePara elsevierViewall">En el caso de los marcajes o sustituciones con un elemento radiactivo&#44; lo correcto ser&#237;a hablar de &#171;marcaje con fl&#250;or-18&#187; &#40;p&#46;<span class="elsevierStyleHsp" style=""></span>ej&#46;&#41; y no es correcto hablar de &#171;radiomarcaje con fl&#250;or&#187;&#44; o &#171;radiomarcaje con fl&#250;or-18&#187; o &#171;marcaje con <span class="elsevierStyleSup">18</span>F&#187;&#59; o en su caso lo correcto ser&#237;a hablar de &#171;compuesto marcado con galio-68&#187; y no de &#171;compuesto marcado con &#91;68Ga&#93;&#187; o &#171;compuesto radiomarcado con galio&#187;&#46;</p><p id="par0055" class="elsevierStylePara elsevierViewall">Dada la complejidad que la habituaci&#243;n a la nomenclatura adecuada puede conllevar&#44; se ha considerado de utilidad aportar una tabla en la que se recojan los nombres recomendados de algunos de los radiof&#225;rmacos de inter&#233;s &#40;v&#233;ase <a class="elsevierStyleCrossRef" href="#tbl0005">tabla 1</a>&#41; para facilitar la tarea de transici&#243;n a este sistema por parte de los autores de los manuscritos remitidos a la REMNIM&#46;</p><elsevierMultimedia ident="tbl0005"></elsevierMultimedia><p id="par0060" class="elsevierStylePara elsevierViewall">En cualquier caso&#44; si bien lo adecuado es utilizar el nombre propuesto&#44; 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                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&#91;<span class="elsevierStyleSup">18</span>F&#93;F-PSMA-1007&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleSup">18</span>F-PSMA-1007&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&#91;<span class="elsevierStyleSup">18</span>F&#93;F-timidina&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleSup">18</span>F-Timidina&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&#91;<span class="elsevierStyleSup">18</span>F&#93;fluciclovina&#91;<span class="elsevierStyleSup">18</span>F&#93;FACBC&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleSup">18</span>F-Fluciclovina&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&#91;<span class="elsevierStyleSup">18</span>F&#93;fludeoxiglucosa&#91;<span class="elsevierStyleSup">18</span>F&#93;FDG&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleSup"><span class="elsevierStyleSmallCaps">18</span></span><span class="elsevierStyleSmallCaps">FDG</span>&#44; fludeoxiglucosa&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&#91;<span class="elsevierStyleSup">18</span>F&#93;fluorocolina&#91;<span class="elsevierStyleSup">18</span>F&#93;F-Colina&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleSup">18</span>F-Fluorocolina&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&#91;<span class="elsevierStyleSup">18</span>F&#93;NaF&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleSup">18</span>F-NaF&#44;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">6-&#91;<span class="elsevierStyleSup">18</span>F&#93;fluorolevodopa&#44;L-6-&#91;<span class="elsevierStyleSup">18</span>F&#93;fluorodopa&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleSup">18</span>F-DOPA&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">L-&#91;etil-<span class="elsevierStyleSup">18</span>F&#93;tirosina&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleSup">18</span>F-tirosina&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&#91;<span class="elsevierStyleSup">67</span>Ga&#93;Ga-Citrato&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleSup">67</span>Ga-Citrato&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&#91;<span class="elsevierStyleSup">68</span>Ga&#93;Ga-DOTA-TOC&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleSup">68</span>Ga-DOTATOC&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&#91;<span class="elsevierStyleSup">68</span>Ga&#93;Ga-PSMA-11&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleSup">68</span>Ga-PSMA11&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&#91;<span class="elsevierStyleSup">89</span>Zr&#93;Zr-DFO-Trastuzumab&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleSup">89</span>Zr-DFO-Trastuzumab&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&#91;<span class="elsevierStyleSup">99m</span>Tc&#93;NaTcO<span class="elsevierStyleInf">4</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t">Pertectenato s&#243;dico&#44; <span class="elsevierStyleSup">99m</span>TcO<span class="elsevierStyleInf">4</span>Na&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&#91;<span class="elsevierStyleSup">99m</span>Tc&#93;Tc-DMSA&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t"><span class="elsevierStyleSup">99m</span>Tc-DMSA&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&#91;<span class="elsevierStyleSup">99m</span>Tc&#93;Tc-DPD&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t"><span class="elsevierStyleSup">99m</span>Tc-DPD&#44; Tc-DPD&#44; DPD&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
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                  \t\t\t\t">&#91;<span class="elsevierStyleSup">99m</span>Tc&#93;Tc-DTPA&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t"><span class="elsevierStyleSup">99m</span>Tc-DTPA&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&#91;<span class="elsevierStyleSup">99m</span>Tc&#93;Tc-ECD&#44; &#91;<span class="elsevierStyleSup">99m</span>Tc&#93;Tc-bicisato&#91;<span class="elsevierStyleSup">99m</span>Tc&#93;Tc-dietilcisteinato&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t"><span class="elsevierStyleSup">99m</span>Tc-ECD&#44; tecnecio bicisato&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&#91;<span class="elsevierStyleSup">99m</span>Tc&#93;Tc-fitato&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t"><span class="elsevierStyleSup">99m</span>Tc-Fitato&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&#91;<span class="elsevierStyleSup">99m</span>Tc&#93;Tc-HSA&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t"><span class="elsevierStyleSup">99m</span>Tc-HSA&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&#91;<span class="elsevierStyleSup">99m</span>Tc&#93;Tc-HDP&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleSup">99m</span>TcHDP&#44; Tc-HDP&#44; tecnecio HDP&#44; HDP&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&#91;<span class="elsevierStyleSup">99m</span>Tc&#93;Tc-HMPAO&#91;<span class="elsevierStyleSup">99m</span>Tc&#93;Tc-exametazima&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleSup">99m</span>Tc-HMPAO&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&#91;<span class="elsevierStyleSup">99m</span>Tc&#93;Tc-MDP&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleSup">99m</span>Tc-MDP&#44; Tc-MDP&#44; MDP&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&#91;<span class="elsevierStyleSup">99m</span>Tc&#93;Tc-mebrofenina&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleSup">99m</span>Tc-Mebrofenina&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&#91;<span class="elsevierStyleSup">99m</span>Tc&#93;Tc-MIBI&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Tc-MIBI&#44; MIBI&#44; SESTAMIBI&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&#91;<span class="elsevierStyleSup">99m</span>Tc&#93;Tc-PYP&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleSup">99m</span>Tc-PyP&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&#91;<span class="elsevierStyleSup">99m</span>Tc&#93;Tc-tetrofosmina&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleSup">99m</span>Tc-Tetrofosmina&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&#91;<span class="elsevierStyleSup">111</span>In&#93;In-oxina&#91;<span class="elsevierStyleSup">111</span>In&#93;&#91;In&#40;oxiquinolina&#41;<span class="elsevierStyleInf">3</span>&#93;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Indio-oxina&#44; <span class="elsevierStyleSup">111</span>In-oxina&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&#91;<span class="elsevierStyleSup">111</span>In&#93;InCl<span class="elsevierStyleInf">3</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t"><span class="elsevierStyleSup">111</span>InCl<span class="elsevierStyleInf">3</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
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                  \t\t\t\t">&#91;<span class="elsevierStyleSup">123</span>I&#93;IBZM&#91;<span class="elsevierStyleSup">123</span>I&#93;Iodobenzamida&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t\ttable-entry\n
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