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Inicio Acta Otorrinolaringológica Española Estudio sobre las metástasis cervicales de primario desconocido
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Vol. 53. Issue 8.
Pages 601-606 (October 2002)
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Vol. 53. Issue 8.
Pages 601-606 (October 2002)
Estudio sobre las metástasis cervicales de primario desconocido
Study of cervical metastases from unknown primary tumour
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P. Vaamonde
Corresponding author
pvaamondel@seorl.org

Correspondencia: PLaza de Ultreia, 3, 1°B. 15704 Santiago de Compostela.
, C. Martín Martín, M. Del Río Valeiras, T. Labella Caballero
Cátedra y servicio de otorrinolaringología. Universidad y hospital clínico-universitario de santiago de compostela
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Resumen

Las metástasis cervicales por un tumor de origen desconocido (MCOD), aunque infrecuentes, suponen un reto diagnóstico y terapéutico para el otorrinolaringólogo. Presentamos un estudio retrospectivo sobre 22 pacientes con MCOD diagnosticados en nuestro Servicio en un período de 13 años (3,4% de los pacientes con cáncer cérvico-facial). La sensibilidad de la PAAF fue de 94,7%. El 54% correspondieron a N2a, el 9% a N2b, y el 36% a N3. El 73% de los casos fueron carcinomas epidermoides y un 27% eran indiferenciados. Presentamos nuestro protocolo diagnóstico y terapéutico: una panendoscopia con biopsia a ciegas de nasofaringe, vallécula y seno piriforme; y amigdalectomía homolateral asociada. Con su utilización encontramos el tumor primario en un 23% de los casos. Todos los carcinomas epidermoides fueron tratados mediante vaciamiento cervical radical y radioterapia, y los 6 carcinomas indiferenciados fueron tratados mediante quimioterapia y radioterapia. Hemos obtenido una supervivencia global a los tres años del 62%. El estadio N influyó en la supervivencia.

Palabras clave:
Metástasis cervicales
Primario de origen desconocido
Carcinoma epidermoide
Abstract

Cervical metastases of cancer of an unknown primary tumour (CMUPT) are infrequent but they represent botha diagnostic and therapeutic challenge for ENT physicians. We present a retrospective study over 22 patients with CMUPT diagnosed in our hospital during 13 years (3.4% of the patients with head and neck cancer). The sensitivity of the fine-needle aspiration technique was 94.7%. 54% were N2a, 36% N3 and 9% N2b. 73% were squamous cell carcinoma and 27% were undifferentiated carcinoma. We established our protocol on diagnosis and management: panendoscopy with biopsies of nasopharynx, vallecula and pyriform sinus and ipsilateral tonsillectomy. The primary source was identified in 23% of the series. All squamous cell carcinoma were treated with radical neck surgery plus radiotherapy and the undifferentiated carcinoma with chemotherapy and radiotherapy. The overall survival was 64% at 3 years. The N-stage affected the survival rate.

Key words:
Cervical metastases
Unknown primary neoplasm
Squamous cell carcinoma

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