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Inicio Acta Otorrinolaringológica Española Patrón de afectación coclear en la otitis media aguda recidivante
Journal Information
Vol. 56. Issue 9.
Pages 396-399 (November 2005)
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Vol. 56. Issue 9.
Pages 396-399 (November 2005)
Patrón de afectación coclear en la otitis media aguda recidivante
Cochlear afectation in acute otitis media
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2720
E. Bodet
Corresponding author
ebodet@hotmail.com

Correspondencia: Eduard Bodet Agustí Unidad de Otorrinolaringología Hospital Nostra Senyora de Meritxell Avinguda Fiter i Rossell, 1-13 Escaldes-Engordany. Principat d´Andorra.
, V. Martínez, C. Romeu
Hospital Nostra Senyora de Meritxell. Andorra.
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Resumen
Objetivo

Para entender mejor el origen de la hipoacusia neurosensorial asociada a los procesos infecciosos del oído medio, proponemos un estudio experimental con ratas de laboratorio.

Material y métodos

Treinta ejemplares de rata Sprague-Dawley son divididas en dos grupos, a los que se les provocan respectivamente uno y dos episodios de otitis media aguda. Tras someter el oído interno de cada ejemplar a un método de preparación de muestras de superficie, estudiamos el órgano de Corti con microscopia electrónica de escáner.

Resultados

El análisis estadístico de los datos obtenidos demuestra una pérdida mayor de células ciliadas en la espira basal del primer (a=0,020) y segundo (a=0,038) grupos. En la espira media del primer grupo no existen prácticamente lesiones celulares, que sí están presentes en todas las muestras del segundo (a=0,002).

Conclusiones

En la otitis media aguda, la pérdida de células ciliadas se localiza en la espira basal de la cóclea y se extiende hasta la espira media cuando el episodio de otitis se repite.

Palabras clave:
Otitis media
Células ciliadas
Lesión coclear
Objective
Abstract

An experimental design with mice has been realized to understand the origin of sensorial hearing loss related to infectious processes in the middle ear. Our aim is to study if the cilliated cells in the Corti organ’s are lost after one or more acute otitis media.

Materials and Methods

For that, thirty Sprague-Dawley mice have been divided in two groups. In the first one, we have induced one acute otitis media, in the second group we have induced two infections of this kind.

Results

The statistic study shows that the loss of the cilliated cells is greater in the basal turn of the mice is cochlea, in the first group (a=0,020) and also in the second (a=0,038). We’ve noticed in the first group the near absence of injury in the middle turn, but in all samples of the second group we found that injury (a=0,002).

Conclusions

In acute otitis media, the loss of cilliated cells are mainly in the basal turn of the mice is cochlea, and affects the middle turn when the infection is repeated.

Key words:
Acute otitis media
Cilium cells
Cochlear damage

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