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Inicio Acta Otorrinolaringológica Española Segundos tumores primarios en el cáncer escamoso de cabeza y cuello
Journal Information
Vol. 57. Issue 10.
Pages 462-466 (December 2006)
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Vol. 57. Issue 10.
Pages 462-466 (December 2006)
Segundos tumores primarios en el cáncer escamoso de cabeza y cuello
Second primary tumors in head and neck cancer
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2885
C.A. Álvarez Marcos1,1
Corresponding author
alvarezmarcos@telefonica.net

Correspondencia: César Antonio Álvarez Marcos. Las Alondras 19. 33013 Oviedo (Asturias).
, H. Fernández Espina1, J.L. Llorente Pendás2, V. Franco Gutiérrez2, M.A.J.A. Hermsen2, M.P. Cuesta Albalad2, C. Suárez Nieto2
Servicio de Otorrinolaringología. Hospital Valle del Nalón. Riaño-Langreo
Servicio de Otorrinolaringología. Hospital Universitario Central de Asturias. Oviedo
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Resumen
Introducción

El desarrollo de un segundo tumor primario (STP) en el cáncer escamoso de cabeza y cuello (CECC) presenta elevada mortalidad y condiciona la decisión terapéutica.

Objetivo

Describir las características clínicas de los STP y determinar su implicación en la supervivencia.

Material y método

Revisión de 633 pacientes con CECC entre 1984-2004 describiendo las principales características de los STP.

Resultados

Se observan en el 11% de los CECC. Los tumores índice que se asocian más a un STP son los de laringe supraglótica (21%) y cavidad oral (16%). Los STP ocurren sobre todo en el área de cabeza y cuello (47%), pulmón (32%) y esófago (11%). Tienen gran impacto en la supervivencia de los pacientes con CECC, reduciéndola en un 30% (23% versus 53% en el grupo control).

Conclusiones

Debido a la alta incidencia de STP es necesario profundizar en su estudio para realizar una prevención adecuada y un tratamiento eficaz.

Palabras clave:
Cáncer de cabeza y cuello
Campo de cancerización
Segundos tumores primarios
Abstract
Introduction

The development of second primary tumors (SPT) in patients with head and neck squamous cell carcinoma (HNSCC) has become an increasingly important factor in clinical treatment decisions.

Purpose

To define favourable clinical characteristics for overall survival, in patients with SP head and neck cancer.

Material and method

Records of 633 patients with SCC treated from 1984 to 2004 were reviewed to describe clinical characteristics of the SPT.

Results

The overall incidence of SPT was 11%. The incidence of the index tumors was as follows: supraglottic cancer 21% and oral cancer 16%. The most common SPT occurred in head and neck area in 47%, lung in 32% and esophagus in 11%. Second primary was associated with a poor 5 years survival in patients with HN-SCC (23 versus 53% in control group).

Conclusion

Because of the high rate of second primary tumors, protocols including chemoprophylaxis should be investigated. Prevention and early detection are indicated.

Keywords:
Head
neck cancer
Field cancerization
Second primary tumors

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