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Journal Information
Vol. 58. Issue 6.
Pages 232-238 (January 2007)
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Vol. 58. Issue 6.
Pages 232-238 (January 2007)
Hearing Impairment in Patients With Rheumatoid Arthritis
Deterioro auditivo en pacientes con artritis reumatoide
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Francisco Javier García Callejo
Corresponding author
jgarciacall@hotmail.com

Correspondence: Luis Oliag, 71, 8. 46006 Valencia. España.
, Noemí Conill Tobías, Noelia Muñoz Fernández, Carlos de Paula Vernetta, Ignacio Alonso Castañeira, Jaime Marco Algarra
Servicio de Otorrinolaringología, Hospital Clínico Universitario de Valencia, Universidad de Valencia, Valencia, Spain
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Objective

To evaluate the characteristics of hearing loss (HL) in patients with rheumatoid arthritis (RA).

Patients and method

Acomparative case-control study was performed with 194 patients and 107 healthy subjects. All of them were submitted to pure-tone audiometry and detection of inflammatory parameters and Western blot for anticochlear antibodies.

Results

: HL was detected in 42.7% of patients with RA(15.9% in controls; P<.001). This was sensorineural in 38.6%. Three or more altered blood parameters appeared in 28.9% of patients with RA (17.6% in controls; P<.01). We observed positive Western blot in 12% of patients with RA and HL and none among healthy controls.

Conclusions

There is a predisposition to HL, mainly sensorineural, in RA. In view of this prevalence, audiologic reviews must be performed to try to determine if this disorder shows an immunomediated aspect so that a therapeutic alternative could modify the course of HL.

Key words:
Hearing loss
Rheumatoid arthritis
Pure-tone audiometry
Objetivo

Valorar la relación de la hipoacusia con la artritis reumatoide (AR).

Pacientes y método

Estudio comparativo de casos y controles equiparados en edad y sexo, de 194 pacientes con AR y 107 sujetos sanos. Se efectuó en todos valoración mediante audiometría tonal y determinación de parámetros inflamatorios y Western blot de anticuerpos anticocleares.

Resultados

El 42,7% de los pacientes con AR presentaron hipoacusia (el 15,9% de los controles; p<0,001). En el 38,6% de ellos fue neurosensorial. El 28,9% de los casos presentaron 3 o más parámetros alterados (el 17,6% de los controles; p<0,01). El 12% de los sujetos con AR e hipoacusia tuvieron un Western blot positivo. No se detectó ninguno en los controles.

Conclusiones

Hay una predisposición a la hipoacusia en los sujetos con AR, principalmente neurosensorial. Esta prevalencia obliga a la revisión audiológica de este grupo e intentar definir si este trastorno tiene un componente inmunomediado que permitiera un tratamiento modificador del curso de la hipoacusia.

Palabras clave:
Hipoacusia
Artritis reumatoide
Audiometría tonal

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