Solitary fibrous tumor of the renal hilum: A rare a diagnosis for a not so rare clinical picture

Rodríguez-Moreno, J.F.; Conde, E.; Duran, I.

doi:10.1016/j.acuroe.2012.03.006

array:23 ["pii" => "S2173578612001941" "issn" => "21735786" "doi" => "10.1016/j.acuroe.2012.03.006" "estado" => "S300" "fechaPublicacion" => "2012-09-01" "aid" => "453" "copyright" => "AEU" "copyrightAnyo" => "2012" "documento" => "simple-article" "crossmark" => 0 "subdocumento" => "cor" "cita" => "Actas Urol Esp. 2012;36:505-6" "abierto" => array:3 [ "ES" => false "ES2" => false "LATM" => false ] "gratuito" => false "lecturas" => array:2 [ "total" => 1225 "formatos" => array:3 [ "EPUB" => 13 "HTML" => 933 "PDF" => 279 ] ] "Traduccion" => array:1 [ "es" => array:19 [ "pii" => "S0210480612002070" "issn" => "02104806" "doi" => "10.1016/j.acuro.2012.03.017" "estado" => "S300" "fechaPublicacion" => "2012-09-01" "aid" => "453" "copyright" => "AEU" "documento" => "simple-article" "crossmark" => 0 "subdocumento" => "cor" "cita" => "Actas Urol Esp. 2012;36:505-6" "abierto" => array:3 [ "ES" => false "ES2" => false "LATM" => false ] "gratuito" => false "lecturas" => array:2 [ "total" => 1735 "formatos" => array:3 [ "EPUB" => 8 "HTML" => 1162 "PDF" => 565 ] ] "es" => array:11 [ "idiomaDefecto" => true "cabecera" => "Carta al Director" "titulo" => "Tumor fibroso solitario del hilio renal: un diagnóstico poco común de un cuadro clínico no tan raro" "tienePdf" => "es" "tieneTextoCompleto" => "es" "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "505" "paginaFinal" => "506" ] ] "titulosAlternativos" => array:1 [ "en" => array:1 [ "titulo" => "Solitary Fibrous Tumor of the Renal Hilum: A Rare a Diagnosis for a not so Rare Clinical Picture" ] ] "contieneTextoCompleto" => array:1 [ "es" => true ] "contienePdf" => array:1 [ "es" => true ] "resumenGrafico" => array:2 [ "original" => 0 "multimedia" => array:7 [ "identificador" => "fig0005" "etiqueta" => "Figura 1" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr1.jpeg" "Alto" => 1370 "Ancho" => 2667 "Tamanyo" => 502556 ] ] "descripcion" => array:1 [ "es" => "A. Tomografía computarizada abdominal que muestra una masa pararrenal con aumento del contraste. B. Hematoxilina y sección de parafina teñida con eosina que muestra la resección de TFS y su tinción inmunohistoquímica con positividad para CD99 y CD34." ] ] ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "J.F. Rodríguez-Moreno, E. Conde, I. Duran" "autores" => array:3 [ 0 => array:2 [ "nombre" => "J.F." "apellidos" => "Rodríguez-Moreno" ] 1 => array:2 [ "nombre" => "E." "apellidos" => "Conde" ] 2 => array:2 [ "nombre" => "I." "apellidos" => "Duran" ] ] ] ] ] "idiomaDefecto" => "es" "Traduccion" => array:1 [ "en" => array:9 [ "pii" => "S2173578612001941" "doi" => "10.1016/j.acuroe.2012.03.006" "estado" => "S300" "subdocumento" => "" "abierto" => array:3 [ "ES" => false "ES2" => false "LATM" => false ] "gratuito" => false "lecturas" => array:1 [ "total" => 0 ] "idiomaDefecto" => "en" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2173578612001941?idApp=UINPBA00004N" ] ] "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0210480612002070?idApp=UINPBA00004N" "url" => "/02104806/0000003600000008/v2_201304261446/S0210480612002070/v2_201304261446/es/main.assets" ] ] "itemAnterior" => array:19 [ "pii" => "S217357861200193X" "issn" => "21735786" "doi" => "10.1016/j.acuroe.2012.11.002" "estado" => "S300" "fechaPublicacion" => "2012-09-01" "aid" => "435" "copyright" => "AEU" "documento" => "simple-article" "crossmark" => 0 "subdocumento" => "cor" "cita" => "Actas Urol Esp. 2012;36:504" "abierto" => array:3 [ "ES" => false "ES2" => false "LATM" => false ] "gratuito" => false "lecturas" => array:2 [ "total" => 785 "formatos" => array:3 [ "EPUB" => 8 "HTML" => 604 "PDF" => 173 ] ] "en" => array:10 [ "idiomaDefecto" => true "cabecera" => "Letter to the Editor" "titulo" => "Prostate specific antigen decrease and prostate cancer diagnosis: Recognizing the fundamental previous progresses and moving forward" "tienePdf" => "en" "tieneTextoCompleto" => "en" "paginas" => array:1 [ 0 => array:1 [ "paginaInicial" => "504" ] ] "titulosAlternativos" => array:1 [ "es" => array:1 [ "titulo" => "Reducción del antígeno específico de próstata y diagnóstico de cáncer de próstata: reconocer los progresos previos fundamentales y avanzar" ] ] "contieneTextoCompleto" => array:1 [ "en" => true ] "contienePdf" => array:1 [ "en" => true ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "L. Oliveira-Reis" "autores" => array:1 [ 0 => array:2 [ "nombre" => "L." "apellidos" => "Oliveira-Reis" ] ] ] ] ] "idiomaDefecto" => "en" "Traduccion" => array:1 [ "es" => array:9 [ "pii" => "S0210480612001180" "doi" => "10.1016/j.acuro.2012.03.013" "estado" => "S300" "subdocumento" => "" "abierto" => array:3 [ "ES" => false "ES2" => false "LATM" => false ] "gratuito" => false "lecturas" => array:1 [ "total" => 0 ] "idiomaDefecto" => "es" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0210480612001180?idApp=UINPBA00004N" ] ] "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S217357861200193X?idApp=UINPBA00004N" "url" => "/21735786/0000003600000008/v1_201304251954/S217357861200193X/v1_201304251954/en/main.assets" ] "en" => array:15 [ "idiomaDefecto" => true "cabecera" => "Letter to the Editor" "titulo" => "Solitary fibrous tumor of the renal hilum: A rare a diagnosis for a not so rare clinical picture" "tieneTextoCompleto" => true "saludo" => "Dear Editor:" "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "505" "paginaFinal" => "506" ] ] "autores" => array:1 [ 0 => array:4 [ "autoresLista" => "J.F. Rodríguez-Moreno, E. Conde, I. Duran" "autores" => array:3 [ 0 => array:3 [ "nombre" => "J.F." "apellidos" => "Rodríguez-Moreno" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "a" "identificador" => "aff0005" ] ] ] 1 => array:3 [ "nombre" => "E." "apellidos" => "Conde" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "b" "identificador" => "aff0010" ] ] ] 2 => array:4 [ "nombre" => "I." "apellidos" => "Duran" "email" => array:2 [ 0 => "ignacioduran@hospitaldemadrid.com" 1 => "duranign@gmail.com" ] "referencia" => array:3 [ 0 => array:2 [ "etiqueta" => "a" "identificador" => "aff0005" ] 1 => array:2 [ "etiqueta" => "c" "identificador" => "aff0015" ] 2 => array:2 [ "etiqueta" => "¿" "identificador" => "cor0005" ] ] ] ] "afiliaciones" => array:3 [ 0 => array:3 [ "entidad" => "División de Oncología Médica, Centro Integral Oncológico Clara Campal, Madrid, Spain" "etiqueta" => "a" "identificador" => "aff0005" ] 1 => array:3 [ "entidad" => "Laboratorio de Dianas Terapéuticas, Hospital Universitario San Chinarro, Madrid, Spain" "etiqueta" => "b" "identificador" => "aff0010" ] 2 => array:3 [ "entidad" => "Facultad de Medicina, Universidad San Pablo CEU, Madrid, Spain" "etiqueta" => "c" "identificador" => "aff0015" ] ] "correspondencia" => array:1 [ 0 => array:3 [ "identificador" => "cor0005" "etiqueta" => "⁎" "correspondencia" => "Corresponding author." ] ] ] ] "titulosAlternativos" => array:1 [ "es" => array:1 [ "titulo" => "Tumor fibroso solitario del hilio renal: un diagnóstico poco común de un cuadro clínico no tan raro" ] ] "resumenGrafico" => array:2 [ "original" => 0 "multimedia" => array:7 [ "identificador" => "fig0005" "etiqueta" => "Figure 1" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr1.jpeg" "Alto" => 1371 "Ancho" => 2668 "Tamanyo" => 562488 ] ] "descripcion" => array:1 [ "en" => "(a) Abdominal computed tomography showing a pararenal mass with contrast enhancement. (b) Hemotoxylin and eosin-stained paraffin section showing the SFT resected and its immunohistochemistry staining with positivity for CD99 and CD34." ] ] ] "textoCompleto" => "Imaging studies such as computed tomography (CT) or ultrasound are becoming more and more frequent in our routine clinical practice. Often these techniques identified masses in the kidney but cannot always distinguish between renal cell carcinomas, metastases, carcinomas of the upper urinary tract, or benign renal tumors.Surgical resection, which provides tissue for accurate diagnosis as well as definitive therapy, remains the standard approach for most patients who present with renal masses. However, a common clinical problem is the management of patients with small lesions or those of uncertain malignant potential. Also, elderly patients with multiple comorbidities represent a subgroup in which a customized approach is frequently required.Percutaneous biopsy or fine needle aspiration with image guidance may be an alternative in selected cases.<a class="elsevierStyleCrossRef" href="#bib0005">1</a> Yet, these techniques have not been widely utilized, because of concern about haemorrhage or tumor seeding along the needle track. Nevertheless, percutaneous biopsy may be an alternative in selected patients in whom surgery may entail significant risk.<a class="elsevierStyleCrossRef" href="#bib0010">2</a>In this regard, we saw in our institution a 47-year-old female in whom an abdominal CT scan performed as a study of unspecific abdominal pain revealed an ovoid mass of 26mm×17mm×28mm. compressing the right renal pelvis with avid contrast enhancement and intra-lesion calcifications and no signs of disease spread (<a class="elsevierStyleCrossRef" href="#fig0005">Fig. 1</a>a). A radical nephrectomy was performed and histopathological analysis showed a solitary fibrous tumor (SFT). The renal hilum contained a 2.3-cm mass of adipose tissue. Microscopically, the neoplasm was separated from the kidney and the renal pelvis parenchyma and it was composed of round to spindle-shaped tumour cells arranged in hypercellular and hypocellular areas separated by thick bands of collagen. No necrosis or atypia were observed and the mitotic index was low. Tumor cells stained positive for CD34, CD99, Vimentin and Bcl2 and no staining was observed for AE1/AE3, MelanA, HMB45, smooth muscle actin, CD10, Desmin and S-100 protein (<a class="elsevierStyleCrossRef" href="#fig0005">Fig. 1</a>b).<elsevierMultimedia ident="fig0005"></elsevierMultimedia>SFT is an unusual mesenchymal neoplasm that shows a prominent hemangiopericytoma (HPC)-like branching vascular pattern, and in fact SFT and HPC share histological features and have almost identical gene expression profiles, so they are now grouped as one entity.<a class="elsevierStyleCrossRef" href="#bib0015">3</a>SFT/HPC is more common in middle-aged adults and it occurs most frequently in the pleura. Surgical resection is the gold standard and it is curative in many cases. Nevertheless, some reports reveal a metastatic potential even early in the course of the disease.SFT/HPC is rarely diagnosed in genitourinary (GU) oncology. It presents as well circumscribed masses that histologically consist of tightly packed spindle cells separated by bands of hyalinized collagen and branching blood vessels. Most SFT/HPC are indolent although some can behave as high-grade sarcomas. There is a rare form (i.e. Doege-Potter syndrome) where patients present with very large masses and hypoglycemia induced by tumor cells production of IGF-2. Radiological findings in the diagnosis of SFT usually reveal large tumors, with discrete margins and avid contrast enhancement.<a class="elsevierStyleCrossRef" href="#bib0020">4</a> Resection of these tumors is curative in most cases, but rare recurrences might occur mostly in tumors larger than 10cm. Doxorubicin-based chemotherapy has scarce activity in the metastatic or unresectable setting. Targeted therapy inhibiting platelet-derived growth factor receptor or vascular endothelial growth factor has recently shown clinical activity in these patients and can represent an alternative treatment.This case illustrates a rare entity in GU oncology and attempts to summarize its clinical presentation, pathology, and management. It also shows how accurate diagnosis of renal masses remains a challenge for the physicians involved in GU oncology." "pdfFichero" => "main.pdf" "tienePdf" => true "NotaPie" => array:1 [ 0 => array:2 [ "etiqueta" => "☆" "nota" => "Please cite this article as: Rodríguez-Moreno JF, et al. Tumor fibroso solitario del hilio renal: un diagnóstico poco común de un cuadro clínico no tan raro. Actas Urol Esp. 2012;36:505–6." ] ] "multimedia" => array:1 [ 0 => array:7 [ "identificador" => "fig0005" "etiqueta" => "Figure 1" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr1.jpeg" "Alto" => 1371 "Ancho" => 2668 "Tamanyo" => 562488 ] ] "descripcion" => array:1 [ "en" => "(a) Abdominal computed tomography showing a pararenal mass with contrast enhancement. (b) Hemotoxylin and eosin-stained paraffin section showing the SFT resected and its immunohistochemistry staining with positivity for CD99 and CD34." ] ] ] "bibliografia" => array:2 [ "titulo" => "References" "seccion" => array:1 [ 0 => array:2 [ "identificador" => "bibs0005" "bibliografiaReferencia" => array:4 [ 0 => array:3 [ "identificador" => "bib0005" "etiqueta" => "1" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Percutaneous core biopsy for renal masses: indications, accuracy and results" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "T. Lebret" 1 => "J.E. Poulain" 2 => "V. Molinie" 3 => "J.M. Herve" 4 => "Y. Denoux" 5 => "A. Guth" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1016/j.juro.2007.05.155" "Revista" => array:5 [ "tituloSerie" => "J Urol" "fecha" => "2007" "volumen" => "178" "paginaInicial" => "1184" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/17698122" "web" => "Medline" ] ] ] ] ] ] ] ] 1 => array:3 [ "identificador" => "bib0010" "etiqueta" => "2" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Techniques, safety and accuracy of sampling of renal tumors by fine needle aspiration and core biopsy" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "A. Volpe" 1 => "J.R. Kachura" 2 => "W.R. Geddie" 3 => "A.J. Evans" 4 => "A. Gharajeh" 5 => "A. Saravanan" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1016/j.juro.2007.03.131" "Revista" => array:5 [ "tituloSerie" => "J Urol" "fecha" => "2007" "volumen" => "178" "paginaInicial" => "379" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/17561170" "web" => "Medline" ] ] ] ] ] ] ] ] 2 => array:3 [ "identificador" => "bib0015" "etiqueta" => "3" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Solitary fibrous tumor and haemangiopericytoma: evolution of a concept" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "C. Gengler" 1 => "L. Guillou" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1111/j.1365-2559.2005.02290.x" "Revista" => array:7 [ "tituloSerie" => "Histopathology" "fecha" => "2006" "volumen" => "48" "paginaInicial" => "63" "paginaFinal" => "74" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/16359538" "web" => "Medline" ] ] "itemHostRev" => array:3 [ "pii" => "S0140673612617747" "estado" => "S300" "issn" => "01406736" ] ] ] ] ] ] ] 3 => array:3 [ "identificador" => "bib0020" "etiqueta" => "4" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "CT features of solitary fibrous tumor of the pleura: experience in 26 patients" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "L. Cardinale" 1 => "M. Allasia" 2 => "F. Ardissone" 3 => "P. Borasio" 4 => "U. Familiari" 5 => "P. Lausi" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1007/s11547-006-0062-z" "Revista" => array:6 [ "tituloSerie" => "Radiol Med" "fecha" => "2006" "volumen" => "111" "paginaInicial" => "640" "paginaFinal" => "650" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/16791467" "web" => "Medline" ] ] ] ] ] ] ] ] ] ] ] ] ] "idiomaDefecto" => "en" "url" => "/21735786/0000003600000008/v1_201304251954/S2173578612001941/v1_201304251954/en/main.assets" "Apartado" => array:4 [ "identificador" => "6306" "tipo" => "SECCION" "en" => array:2 [ "titulo" => "Letters to the editor" "idiomaDefecto" => true ] "idiomaDefecto" => "en" ] "PDF" => "https://static.elsevier.es/multimedia/21735786/0000003600000008/v1_201304251954/S2173578612001941/v1_201304251954/en/main.pdf?idApp=UINPBA00004N&text.app=https://www.elsevier.es/" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2173578612001941?idApp=UINPBA00004N"]

ISSN: 2173-5786

Actas Urológicas Españolas is an international journal dedicated to urological diseases and renal transplant. It has been the official publication of the Spanish Urology Association since 1974 and of the American Urology Confederation since 2008. Its articles cover all aspects related to urology. Actas Urológicas Españolas, governed by the peer review system (double blinded), is published online in Spanish and English. Consequently, manuscripts may be sent in Spanish or English and bidirectional free cost translation will be provided. It has high visibility and accessibility and is found in the most important data bases, Medline/Pubmed, Emabase, JCR, Ïndice Médico Español, Índice bibliográfico Español en Ciencias de la Salud (IBECS), Cuiden, Dialnet, Hinari, Scopus, Google Scholar.

See more Open Access Option

Indexed in:

Science Citation Index Expanded, Journal of Citation Reports, Index Medicus/MEDLINE, Scopus, EMBASE/Excerpta Medica, IBECS

Subscribe:

Impact factor

The Impact Factor measures the average number of citations received in a particular year by papers published in the journal during the two preceding years.

© Clarivate Analytics, Journal Citation Reports 2022

Impact factor 2023

1.2

Citescore

CiteScore measures average citations received per document published.

Citescore 2023

1.9

SJR

SRJ is a prestige metric based on the idea that not all citations are the same. SJR uses a similar algorithm as the Google page rank; it provides a quantitative and qualitative measure of the journal's impact.

SJR 2023

0.332

SNIP

SNIP measures contextual citation impact by wighting citations based on the total number of citations in a subject field.

SNIP 2023

0.557

View more metrics

Journal Information

Previous article | Next article

Vol. 36. Issue 8.

Pages 505-506 (September 2012)

Lee este artículo en Español

Export reference

Download PDF

Article

These are the options to access the full texts of the publication Actas Urológicas Españolas (English Edition)

Subscriber

If you already have your login data, please click here .

If you have forgotten your password you can you can recover it by clicking here and selecting the option “I have forgotten my password”

Subscribe to

Actas Urológicas Españolas (English Edition)

More information

Purchase

Purchase article

Purchasing article the PDF version will be downloaded

Price 19.34 €

Purchase now

Contact

Phone for subscriptions and reporting of errors

From Monday to Friday from 9 a.m. to 6 p.m. (GMT + 1) except for the months of July and August which will be from 9 a.m. to 3 p.m.

Calls from Spain

932 415 960

Calls from outside Spain

+34 932 415 960

E-mail

atencionalcliente@elsevier.com

Publish in

Actas Urológicas Españolas

Tools

Actas Urológicas Españolas (English Edition) is a member and subscribes the principles of, the Committee on Publication Ethics (COPE)
www.publicationethics.org.

Free access articles

Recommendations on the treatment of metastatic...

Actas Urol Esp. 2024;48:623-31

Changes in benign prostatic hyperplasia management in...

Actas Urol Esp. 2024;48:461-9

Long-term functional success and patient-reported outcomes...

10.1016/j.acuroe.2024.05.014

Indexed in:

Follow us:

Subscribe:

Article

Subscribe to our newsletter