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Journal Information
Vol. 28. Issue 8.
Pages 588-593 (January 2004)
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Vol. 28. Issue 8.
Pages 588-593 (January 2004)
Sensibilidad microbiana de escherichia coli en bacteriurias en el área sanitaria del bierzo en el año 2003
Antimicrobial Susceptibility Of Escherichia Coli Isolated From Bacteriurias In Bierzo Health Area During 2003
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J.M. Sánchez Merinoa,1, J. García Alonsoa, C. Guillán Maquieira*, R. López Medrano**, C. Fuster Foz**, M. Jiménez Rodríguez***
a Servicios de Urología. Hospital del Bierzo. Ponferrada. León
* Ginecología. Hospital del Bierzo. Ponferrada. León
** Microbiología. Hospital del Bierzo. Ponferrada. León
*** Medicina Preventiva. Hospital del Bierzo. Ponferrada. León
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Resumen
Objetivo

Evaluar la sensibilidad a varios antibióticos en cepas de Escherichia coli aisladas en muestras de orina de pacientes hospitalarios y extrahospitalarios.

Material Y Métodos

Se analizaron los urocultivos positivos para Escherichia coli obtenidos de muestras de pacientes hospitalizados y atendidos en consultas externas hospitalarias y atención primaria. Se determinó la sensibilidad de este germen a diecinueve antibióticos de uso hospitalario y/o extrahospitalario.

Resultados

Según el origen hospitalario, consultas externas hospitalarias y atención primaria, respectivamente, la sensibilidad in vitro ha sido la siguiente: imipenem (100%, 100% y 100%; p=NS), amikacina (100%, 100% y 99,7%; p=NS), fosfomicina (98,6%, 98,4% y 99,6%; p=NS), cefepima (96%, 96,9% y 98,3%; p=NS), piperacilina-tazobactam (96%, 95,3% y 96,6%; p=NS), aztreonam (93,5%, 94,7% y 97,7%; p0,001), ceftazidima (93,5%, 94,3% y 97,8%; p0,001), cefotaxima (93,1%, 95% y 97,7%; p0,001), cefixima (92,7%, 94,6% y 96,7%; p0,05), nitrofurantoína (92%, 94,7% y 94,7%; p=NS), cefuroxima (88,4%, 93,1% y 95%; p0,001), amoxicilina-clavulánico (87,7%, 88,7% y 93,8%; p0,001), tobramicina (87%, 93,7% y 93,8%; p0,001), gentamicina (85,9%, 92,8% y 93%; p0,001), cefazolina (84,4%, 88,7% y 91,6%; p0,01), ciprofloxacino (63,8%, 71,4%, 78,4%; p0,001), norfloxacino (63%, 70,8 y 78,2%; p0,001), cotrimoxazol (65,2%, 68,6% y 74,9%; p0,01) y ampicilina (35,5%, 42,5% y 47,8%; p0,01). (NS= No significativo).

Conclusiones

El tratamiento de las infecciones del tracto urinario frecuentemente se inicia de forma empírica. Por este motivo resulta esencial conocer los patrones de sensibilidad de las bacterias potencialmente causantes del cuadro.

Palabras clave:
Infección del tracto urinario
Sensibilidad microbiana
Infección hospitalaria
Infección extrahospitalaria
Abstract
Objective

Sensitivity to antibiotics of Escherichia coli isolated from intrahospital and extrahospital bacteriurias is analized.

Material and Methods

Sensitivity to nineteen antibiotics used in the clinical practise was determined in strains of Escherichia coli isolated from intrahospital and extrahospital bacteriurias.

Results

The prevalence of in-vitro susceptibilities to antibiotics were (hospital, state health service clinic, health center-primary care): imipenem (100%-100%-100%; p=NS), amikacin (100%-100%-99.7%; p=NS), fosfomicyn (98.6%- 98.4%-99.6%; p=NS), cefepime (96%-96.9%-98.3%; p=NS), piperacillin-tazobactam (96%-95.3%-96.6%; p=NS), aztreonam (93.5%-94.7%-97.7%; p0.001), ceftazidime (93.5%-94.3%-97.8%; p0.001), cefotaxime (93.1%-95%-97.7%; p0.001), cefixime (92.7%-94.6%-96.7%; p0.05), nitrofurantoin (92%-94.7%-94.7%; p=NS), cefuroxime (88.4%-93.1%- 95%; p0.001), amoxicillin-clavulanic (87.7% 88.7%-93.8%; p0.001), tobramicyn (87%-93.7%-93.8%; p0.001), gentamcin (85.9%-92.8%-93%; p0.001), cefazolin (84.4% 88.7%-91.6%; p0.01), ciprofloxacin (63.8%-71.4%-78.4%; p0.001), norfloxacin (63%-70.8%-78.2%; p0.001), cotrimoxazole (65.2%-68.6%-74.9%; p0.01) and ampicillin (35.5%-42.5%-47.8%; p0.01). (*NS= No significant differences).

Conclusions

The knowledge of the sensitivity of uropathogens to antimicrobians can allow us to initiate empirical therapy of urinary tract infections.

Key Words:
Urinary tract infection
Antibiotic susceptibility
Intrahospital infection
Community-acquired infection

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