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Inicio Actas Urológicas Españolas (English Edition) Controversies in prostate cancer management: Consensus recommendations from expe...
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Vol. 48. Issue 10.
Pages 739-750 (December 2024)
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Vol. 48. Issue 10.
Pages 739-750 (December 2024)
Special article
Controversies in prostate cancer management: Consensus recommendations from experts in northern Spain
Controversias en el abordaje del cáncer de próstata: consenso de recomendaciones de expertos del norte de España
D. Pérez Fentesa,
Corresponding author
danielfentes@gmail.com

Corresponding author.
, P. Willischb, S. Martínez Breijooc, M. Domínguezd, U. Anidoe, C. Álvarezf, A. Gómez Caamañog
a Servicio de Urología, Hospital Clínico Universitario Santiago de Compostela, Santiago de Compostela, A Coruña, Spain
b Departamento de Oncología Radioterápica, Hospital Meixoeiro, Vigo, Pontevedra, Spain
c Servicio de Urología, Hospital Universitario de A Coruña, A Coruña, Spain
d Servicio de Urología, Hospital Universitario Marqués de Valdecilla, Santander, Cantabria, Spain
e Departamento de Oncología Médica, Hospital Clínico Universitario Santiago de Compostela, Santiago de Compostela, A Coruña, Spain
f Servicio de Oncología Médica, Hospital Universitario de Asturias, Instituto de Investigación Sanitaria del Principado de Asturias, Oviedo, Asturias, Spain
g Servicio de Oncología Radioterápica, Hospital Clínico Universitario Santiago de Compostela, Santiago de Compostela, A Coruña, Spain
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Tables (4)
Table 1. Management and Imaging Tests in Localized Prostate Cancer.
Table 2. Imaging tests and management in prostate cancer after surgery.
Table 3. Imaging tests and management in biochemical recurrence after radiotherapy.
Table 4. Management of metastatic hormone-sensitive prostate cancer.
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Figures (1)
Abstract

In recent years, various aspects of prostate cancer (PC) management have undergone significant changes, including the implementation of therapeutic strategies such as the use of new hormonal agents like abiraterone, apalutamide, enzalutamide or darolutamide and the incorporation of next generation imaging techniques (NGI). However, the evidence regarding the role of NGI and the therapeutic decision-making based on their findings is not solid. Following the methodology of the Advanced Prostate Cancer Consensus Conference (APCCC), a multidisciplinary expert consensus was developed to address controversial questions concerning the use of NGI and clinical management in four priority scenarios: localized PC, PC after radical prostatectomy, PC after radiotherapy with curative intent, and metastatic hormone-sensitive PC. This consensus represents the opinions of medical oncology, radiation oncology and urology physicians and provides useful recommendations for clinical practice.

Keywords:
Prostatic neoplasms
Consensus
Disease management
Androgen antagonists
Radiotherapy
Docetaxel
Resumen

En los últimos años el manejo del cáncer de próstata (CP) ha presentado cambios relevantes en diferentes aspectos como la implementación de estrategias terapéuticas que incluyen el uso de nuevos agentes hormonales como abiraterona, apalutamida, enzalutamida o darolutamida y la incorporación de técnicas de imagen de nueva generación (NGI). Sin embargo, no hay evidencias sólidas sobre el papel de las NGI y la toma de decisiones terapéuticas que se derivan de sus resultados. Siguiendo la metodología de la Advanced Prostate Cancer Consensus Conference (APCCC), se realizó un consenso multidisciplinar de expertos y se abordaron cuestiones controvertidas sobre el uso de NGI y el manejo clínico en cuatro escenarios considerados prioritarios: CP localizado, CP tras prostatectomía radical o tras radioterapia con intención curativa y CP hormonosensible metastásico. Este consenso refleja la opinión de médicos de oncología médica, oncología radioterápica y de urología y ofrece recomendaciones útiles para la práctica clínica.

Palabras clave:
Neoplasias de la próstata
Consenso
Manejo de la enfermedad
Antagonistas de andrógenos
Radioterapia
Docetaxel

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