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(b) Hemotoxylin and eosin-stained paraffin section showing the SFT resected and its immunohistochemistry staining with positivity for CD99 and CD34.</p>" ] ] ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "J.F. Rodríguez-Moreno, E. Conde, I. Duran" "autores" => array:3 [ 0 => array:2 [ "nombre" => "J.F." "apellidos" => "Rodríguez-Moreno" ] 1 => array:2 [ "nombre" => "E." "apellidos" => "Conde" ] 2 => array:2 [ "nombre" => "I." "apellidos" => "Duran" ] ] ] ] ] "idiomaDefecto" => "en" "Traduccion" => array:1 [ "es" => array:9 [ "pii" => "S0210480612002070" "doi" => "10.1016/j.acuro.2012.03.017" "estado" => "S300" "subdocumento" => "" "abierto" => array:3 [ "ES" => false "ES2" => false "LATM" => false ] "gratuito" => false "lecturas" => array:1 [ "total" => 0 ] "idiomaDefecto" => "es" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0210480612002070?idApp=UINPBA00004N" ] ] "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2173578612001941?idApp=UINPBA00004N" "url" => "/21735786/0000003600000008/v1_201304251954/S2173578612001941/v1_201304251954/en/main.assets" ] "itemAnterior" => array:19 [ "pii" => "S2173578612001928" "issn" => "21735786" "doi" => "10.1016/j.acuroe.2012.05.012" "estado" => "S300" "fechaPublicacion" => "2012-09-01" "aid" => "443" "copyright" => "AEU" "documento" => "simple-article" "crossmark" => 0 "subdocumento" => "cor" "cita" => "Actas Urol Esp. 2012;36:503-4" "abierto" => array:3 [ "ES" => false "ES2" => false "LATM" => false ] "gratuito" => false "lecturas" => array:2 [ "total" => 803 "formatos" => array:3 [ "EPUB" => 12 "HTML" => 636 "PDF" => 155 ] ] "en" => array:11 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Letter to the Editor</span>" "titulo" => "Agreed on medical reports in prostate cancer. APInfo-Cap Project" "tienePdf" => "en" "tieneTextoCompleto" => "en" "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "503" "paginaFinal" => "504" ] ] "titulosAlternativos" => array:1 [ "es" => array:1 [ "titulo" => "Informes médicos consensuados en cáncer de próstata. Proyecto APInfo-Cap" ] ] "contieneTextoCompleto" => array:1 [ "en" => true ] "contienePdf" => array:1 [ "en" => true ] "resumenGrafico" => array:2 [ "original" => 0 "multimedia" => array:7 [ "identificador" => "fig0005" "etiqueta" => "Figure 1" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr1.jpeg" "Alto" => 393 "Ancho" => 485 "Tamanyo" => 47699 ] ] "descripcion" => array:1 [ "en" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Project called APInfo-Cap.</p>" ] ] ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "J.M. Cózar-Olmo, B. Miñana-López" "autores" => array:2 [ 0 => array:2 [ "nombre" => "J.M." "apellidos" => "Cózar-Olmo" ] 1 => array:2 [ "nombre" => "B." "apellidos" => "Miñana-López" ] ] ] ] ] "idiomaDefecto" => "en" "Traduccion" => array:1 [ "es" => array:9 [ "pii" => "S0210480612001684" "doi" => "10.1016/j.acuro.2012.05.002" "estado" => "S300" "subdocumento" => "" "abierto" => array:3 [ "ES" => false "ES2" => false "LATM" => false ] "gratuito" => false "lecturas" => array:1 [ "total" => 0 ] "idiomaDefecto" => "es" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0210480612001684?idApp=UINPBA00004N" ] ] "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2173578612001928?idApp=UINPBA00004N" "url" => "/21735786/0000003600000008/v1_201304251954/S2173578612001928/v1_201304251954/en/main.assets" ] "en" => array:13 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Letter to the Editor</span>" "titulo" => "Prostate specific antigen decrease and prostate cancer diagnosis: Recognizing the fundamental previous progresses and moving forward" "tieneTextoCompleto" => true "saludo" => "Dear Editor:" "paginas" => array:1 [ 0 => array:1 [ "paginaInicial" => "504" ] ] "autores" => array:1 [ 0 => array:3 [ "autoresLista" => "L. Oliveira-Reis" "autores" => array:1 [ 0 => array:3 [ "nombre" => "L." "apellidos" => "Oliveira-Reis" "email" => array:2 [ 0 => "reisleo@unicamp.br" 1 => "reisleonardo@zipmail.com.br" ] ] ] "afiliaciones" => array:1 [ 0 => array:1 [ "entidad" => "Departamento de Cirugía (Urología), Facultad de Ciencias Médicas, Universidad de Campinas, São Paulo, Brazil" ] ] ] ] "titulosAlternativos" => array:1 [ "es" => array:1 [ "titulo" => "Reducción del antígeno específico de próstata y diagnóstico de cáncer de próstata: reconocer los progresos previos fundamentales y avanzar" ] ] "textoCompleto" => "<span class="elsevierStyleSections"><p id="par0005" class="elsevierStylePara elsevierViewall">We have read with interest the recently published article<a class="elsevierStyleCrossRef" href="#bib0005"><span class="elsevierStyleSup">1</span></a> concerning the role of antibiotherapy on the prevention of supposedly unnecessary prostate biopsies in patients with high PSA values and the fact that extremely relevant and contemporary literature was ignored drew our attention. To the best of our knowledge, this scenario was rewritten in January 2010, and, since then,<a class="elsevierStyleCrossRefs" href="#bib0010"><span class="elsevierStyleSup">2–5</span></a> several (dozens) studies have confirmed that piece of data, supporting the authors’ findings.<a class="elsevierStyleCrossRef" href="#bib0005"><span class="elsevierStyleSup">1</span></a></p><p id="par0010" class="elsevierStylePara elsevierViewall">The best evidence nowadays comes from prospective randomized studies. In this regard, our group published for the first time in the literature 2 years ago that regardless if after antibiotics (ciprofloxacin) or placebo, half of the patients presenting high PSA (2.5–10) show PSA decrease; and regardless of the PSA changes: increase, stabilization or decrease (even at levels < 2.5<span class="elsevierStyleHsp" style=""></span>ng/dl), about one third of the patients will present positive prostate biopsy.<a class="elsevierStyleCrossRef" href="#bib0010"><span class="elsevierStyleSup">2</span></a></p><p id="par0015" class="elsevierStylePara elsevierViewall">It is of concern that the authors have biased their discussion and introduction sections recognizing only studies with important methodological flaws, once it is not possible to conclude that biopsies might be avoided if those with PSA decrease are not biopsied. Furthermore, the authors fail in recognizing that the knowledge supporting the fact that there is no clinical role for antibiotics in the decision for prostate biopsy among the patients without clinical prostatitis was previously produced<a class="elsevierStyleCrossRef" href="#bib0010"><span class="elsevierStyleSup">2</span></a> and subsequently confirmed by innumerous studies. Most of the references of the examined study<a class="elsevierStyleCrossRef" href="#bib0005"><span class="elsevierStyleSup">1</span></a> are not current, and this may be corroborated by the under-recognition of important evolutions provided in the last years on the issue.</p><p id="par0020" class="elsevierStylePara elsevierViewall">The authors would be accurate if they acknowledged that this data,<a class="elsevierStyleCrossRef" href="#bib0005"><span class="elsevierStyleSup">1</span></a> besides confirming previous results,<a class="elsevierStyleCrossRefs" href="#bib0010"><span class="elsevierStyleSup">2–5</span></a> may add no role for the association of anti-inflammatory drugs (piroxicam) in this scenario.</p><p id="par0025" class="elsevierStylePara elsevierViewall">In this setting, the main challenges are to accurately identify the patients harboring threatening cancers that will have an impact on quality and quantity of life and to improve the recognition of safe processing windows. Considering the overtreatment involved in prostate cancer management, diagnosing non-threatening cancers is controversial. There is undoubtedly room for improvement and many questions remain.</p></span>" "pdfFichero" => "main.pdf" "tienePdf" => true "NotaPie" => array:1 [ 0 => array:2 [ "etiqueta" => "☆" "nota" => "<p class="elsevierStyleNotepara">Please cite this article as: Oliveira-Reis L. Reducción del antígeno específico de próstata y diagnóstico de cáncer de próstata: reconocer los progresos previos fundamentales y avanzar. Actas Urol Esp.2012;36:504.</p>" ] ] "bibliografia" => array:2 [ "titulo" => "References" "seccion" => array:1 [ 0 => array:2 [ "identificador" => "bibs0005" "bibliografiaReferencia" => array:5 [ 0 => array:3 [ "identificador" => "bib0005" "etiqueta" => "1" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Does antibiotherapy prevent unnecessary prostate biopsies in patients with high PSA values?" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:6 [ 0 => "G. Faydaci" 1 => "B. Eryildirim" 2 => "F. Tarhan" 3 => "C. Goktas" 4 => "C. Tosun" 5 => "U. Kuyumcuoglu" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1016/j.acuro.2011.07.020" "Revista" => array:2 [ "tituloSerie" => "Actas Urol Esp" "fecha" => "2012" ] ] ] ] ] ] 1 => array:3 [ "identificador" => "bib0010" "etiqueta" => "2" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Prostate specific antigen decrease and prostate cancer diagnosis: antibiotic versus placebo prospective randomized clinical trial" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:6 [ 0 => "R.M. Stopiglia" 1 => "U. Ferreira" 2 => "M.M. Silva Jr." 3 => "W.E. Matheus" 4 => "F. Denardi" 5 => "L.O. Reis" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1016/j.juro.2009.11.044" "Revista" => array:6 [ "tituloSerie" => "J Urol" "fecha" => "2010" "volumen" => "183" "paginaInicial" => "940" "paginaFinal" => "944" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/20089269" "web" => "Medline" ] ] ] ] ] ] ] ] 2 => array:3 [ "identificador" => "bib0015" "etiqueta" => "3" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Editorial comment" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "J.N. Krieger" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1016/j.juro.2009.11.116" "Revista" => array:6 [ "tituloSerie" => "J Urol" "fecha" => "2010" "volumen" => "183" "paginaInicial" => "944" "paginaFinal" => "945" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/20089278" "web" => "Medline" ] ] ] ] ] ] ] ] 3 => array:3 [ "identificador" => "bib0020" "etiqueta" => "4" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Editorial comment" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "S. Baltaci" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1016/j.juro.2009.11.116" "Revista" => array:5 [ "tituloSerie" => "J Urol" "fecha" => "2010" "volumen" => "183" "paginaInicial" => "944" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/20089278" "web" => "Medline" ] ] ] ] ] ] ] ] 4 => array:3 [ "identificador" => "bib0025" "etiqueta" => "5" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Re: prostate specific antigen decrease and prostate cancer diagnosis: antibiotic versus placebo prospective randomized clinical trial: R.M. Stopiglia, U. Ferreira, M.M. Silva, W.E. Matheus, F. Denardi and L.O. Reis. J Urol. 2010;183:940–5" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "D.K. Yoon" 1 => "H.S. Park" 2 => "J.Y. Park" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1016/j.juro.2010.06.128" "Revista" => array:6 [ "tituloSerie" => "J Urol" "fecha" => "2010" "volumen" => "184" "paginaInicial" => "2214" "paginaFinal" => "2215" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/20864135" "web" => "Medline" ] ] ] ] ] ] ] ] ] ] ] ] ] "idiomaDefecto" => "en" "url" => "/21735786/0000003600000008/v1_201304251954/S217357861200193X/v1_201304251954/en/main.assets" "Apartado" => array:4 [ "identificador" => "6306" "tipo" => "SECCION" "en" => array:2 [ "titulo" => "Letters to the editor" "idiomaDefecto" => true ] "idiomaDefecto" => "en" ] "PDF" => "https://static.elsevier.es/multimedia/21735786/0000003600000008/v1_201304251954/S217357861200193X/v1_201304251954/en/main.pdf?idApp=UINPBA00004N&text.app=https://www.elsevier.es/" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S217357861200193X?idApp=UINPBA00004N" ]
