Abstracts of the 2022 Annual Meeting of the ALEH
More infometabolic syndrome and alcohol consumption are the leading causes of fatty liver disease. Now, a new term called dual damage has emerged. So far, no studies are reporting the prevalence of dual damage in Mexico. This study aimed to determine the prevalence of metabolic associated fatty liver disease, alcoholic liver disease, and dual damage in the healthy population of the blood bank of our center.
Materials and Methodsdescriptive, cross-sectional, prolective study. We included donors ≥18 years old. We excluded subjects with known liver disease. Vibration-controlled transient hepatic elastography was the method of estimating steatosis and liver fibrosis. We used descriptive statistics.
Results258 donors were included; 129 (50%) have hepatic steatosis: 67 (25.96%) metabolic associated, 31 (12.01%) due to alcohol, and 31 (12.01%) by dual damage. In the metabolic group, S1 was found in 14 subjects (20.90%), S2 in 23 (34.32%), and S3 in 30 (44.78%). 23 (34.32%) were overweight, 23 (34.32%) had obesity grade 1, 11 (16.44%) grade 2, and 5 (7.46%) grade 3. Of the alcohol damage group, 12 (38.70%) had S1, 5 (19.35%) S2, and 13 (41.95%) S3. Beer was the most frequently consumed beverage (61.29%), with the excessive pattern being the most frequent (74.19%), with an average intake of 90.25 grams. 100% of donors with dual damage presented S3 steatosis. Advanced fibrosis was found in 3 (4.47%) metabolic damage donors, 1 (3.22%) by alcohol, and 2 (6.45%) by dual damage.
Conclusions5 out of 10 apparently healthy individuals have fatty liver disease. The most frequent was due to metabolic damage, while fatty liver disease due to alcohol and dual damage were equally prevalent. Undiagnosed advanced fibrosis was found in a small percentage. These individuals are a sample of the Mexican population that could represent the behavior of the population of our country.