P- 46 AMOUNT OF DIETETIC FAT AND CARBOHYDRATE TYPES RELATED TO HEPATIC STEATOSIS IN A GROUP OF MEXICAN ADULTS

Introduction and Objectives

Some studies had described the relation between dietetic fats and carbohydrates with fatty liver disease although any specific amount has not been stablished. This study aimed to analyze the amount and type of dietetic fat and carbohydrates related with hepatic steatosis in a group of Mexican adults in a typical diet.

Materials and Methods

In a group of Mexican adults without hepatic steatosis, a registered cross- sectional study INCMNSZ- 3794- 21/22 consuming a typical diet, were applied food frequency questionnaires, anthropometry and transient elastography. If they had any chronic disease, uncontrolled diabetes, hypertension or thyroid disease, bariatric surgery or pacemaker, were not included. Dietary fat and carbohydrates were identified and quantified with The Food Processor software v11.11.32 (ESHA Co.); manually, the proportion of fats was classified according to WHO recommendations. Differences among steatosis group (CAP> 268 dB/m) were calculated with t- Student and a logistic regression to determine odds ratio with type and amount of nutrients related to hepatic steatosis.

Results

Of 321 participants, 200 were women; 162 had steatosis and were older, with higher BMI, waist circumference, fat mass and visceral fat (p=0.000); they also consumed more carbohydrates, total sugar and added sugars (113.8 g, 98.1 g and 52.6 g, respectively) compared to non- steatosis group (p=0.000). There were no statistical differences in total either type of fats. For carbohydrates were obtained OR= 2.44 (IC95% 1.4- 4.62, p=0.002), total sugar OR= 2.67 (IC95% 1.48- 4.63, p=0.001) and added sugars OR= 2.68 (IC95% 1.49- 4.83, p=0.001).

Conclusions

Unlike fats, type and amounts of dietary sugars are relevant risk factors for hepatic steatosis in a typical Mexican diet. In this study, we identified the amount that could be related to damage for non- alcoholic fatty liver disease.