Precipitating factors of kidney injury in patients with liver cirrhosis

Introduction and Objectives

This study aimed to determine the precipitating factors of acute kidney injury (AKI) in hospitalized patients with ACLD (Advanced chronic liver disease)

Materials and methods

Retrospective, descriptive, cross-sectional study at HJM Gastroenterology service. We included all patients with ACLD hospitalized in the last six months who presented AKI, with a previous baseline creatinine, without proteinuria in the general urinalysis, renal ultrasound without alterations and who met the criteria for AKI by KDIGO. Prognostic scales (Child-Pugh, Meld Na and CLIF Score) were determined to classify into two groups: Those with ACLF and Non-ACLF. The results were analyzed with measures of central tendency.

Results

A total of 47 patients entered the study, divided into two groups: ACLF (N=18) and no-ACLF (N=29) (Table 1).

Conclusions

As can be seen, regardless of the comorbidities and etiology of cirrhosis, the most important factor in acute kidney injury is an impaired liver function associated with infectious processes that can precipitate ACLF and death.

Funding

The resources used in this study were from the hospital without any additional financing

Declaration of interest

The authors declare no potential conflicts of interest.