was read the article
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"documento" => "article" "crossmark" => 0 "licencia" => "http://creativecommons.org/licenses/by-nc-nd/4.0/" "subdocumento" => "cor" "cita" => "Ann Hepatol. 2016;15:803-5" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:2 [ "total" => 194 "formatos" => array:3 [ "EPUB" => 12 "HTML" => 151 "PDF" => 31 ] ] "en" => array:9 [ "idiomaDefecto" => true "titulo" => "Effect of ezetimibe in HCV viral load after liver transplantation" "tienePdf" => "en" "tieneTextoCompleto" => "en" "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "803" "paginaFinal" => "805" ] ] "contieneTextoCompleto" => array:1 [ "en" => true ] "contienePdf" => array:1 [ "en" => true ] "resumenGrafico" => array:2 [ "original" => 0 "multimedia" => array:7 [ "identificador" => "f0005" "etiqueta" => "Figure 1" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr1.jpeg" "Alto" => 401 "Ancho" => 743 "Tamanyo" => 26619 ] ] "descripcion" => array:1 [ "en" => "<p id="sp0005" class="elsevierStyleSimplePara elsevierViewall">Evolution of HCV viral load after liver transplantation.</p>" ] ] ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "Hugo Monrroy-Bravo, Jennifer Angulo, Karla Pino, Pilar Labbé, Marcelo López-Lastra, Alejandro Soza" "autores" => array:6 [ 0 => array:2 [ "nombre" => "Hugo" "apellidos" => "Monrroy-Bravo" ] 1 => array:2 [ "nombre" => "Jennifer" "apellidos" => "Angulo" ] 2 => array:2 [ "nombre" => "Karla" "apellidos" => "Pino" ] 3 => array:2 [ "nombre" => "Pilar" "apellidos" => "Labbé" ] 4 => array:2 [ "nombre" => "Marcelo" "apellidos" => "López-Lastra" ] 5 => array:2 [ "nombre" => "Alejandro" "apellidos" => "Soza" ] ] ] ] ] "idiomaDefecto" => "en" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1665268119306465?idApp=UINPBA00004N" "url" => "/16652681/0000001500000005/v1_201905310950/S1665268119306465/v1_201905310950/en/main.assets" ] "itemAnterior" => array:19 [ "pii" => "S1665268119306441" "issn" => "16652681" "doi" => "10.5604/16652681.1212621" "estado" => "S300" "fechaPublicacion" => "2016-09-01" "aid" => "70465" "copyright" => "Fundación Clínica Médica Sur, A.C." "documento" => "article" "crossmark" => 0 "licencia" => "http://creativecommons.org/licenses/by-nc-nd/4.0/" "subdocumento" => "crp" "cita" => "Ann Hepatol. 2016;15:795-800" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:2 [ "total" => 109 "formatos" => array:3 [ "EPUB" => 17 "HTML" => 50 "PDF" => 42 ] ] "en" => array:11 [ "idiomaDefecto" => true "titulo" => "Bile salt export pump deficiency disease: two novel, late onset, ABCB11 mutations identified by next generation sequencing" "tienePdf" => "en" "tieneTextoCompleto" => "en" "tieneResumen" => "en" "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "795" "paginaFinal" => "800" ] ] "contieneResumen" => array:1 [ "en" => true ] "contieneTextoCompleto" => array:1 [ "en" => true ] "contienePdf" => array:1 [ "en" => true ] "resumenGrafico" => array:2 [ "original" => 0 "multimedia" => array:7 [ "identificador" => "f0005" "etiqueta" => "Figure 1" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr1.jpeg" "Alto" => 266 "Ancho" => 1045 "Tamanyo" => 44190 ] ] "descripcion" => array:1 [ "en" => "<p id="sp0005" class="elsevierStyleSimplePara elsevierViewall">Anti-BSEP pattern at immunochemistry. <span class="elsevierStyleBold">A.</span> In case 1 Anti-BSEP produced an inhomogeneous pattern of staining (reduced and focal) at the canalicular pole of hepatocytes. <span class="elsevierStyleBold">B.</span> In case 2 a multifocal pattern of staining at the canalicular pole of hepatocytes was present. <span class="elsevierStyleBold">C.</span> An anti-MDR3 immune-staining control was reported.</p>" ] ] ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "Giovanni Vitale, Martina Pirillo, Vilma Mantovani, Elena Marasco, Adelia Aquilano, Nesrine Gamal, Paola Francalanci, Fabio Conti, Pietro Andreone" "autores" => array:9 [ 0 => array:2 [ "nombre" => "Giovanni" "apellidos" => "Vitale" ] 1 => array:2 [ "nombre" => "Martina" "apellidos" => "Pirillo" ] 2 => array:2 [ "nombre" => "Vilma" "apellidos" => "Mantovani" ] 3 => array:2 [ "nombre" => "Elena" "apellidos" => "Marasco" ] 4 => array:2 [ "nombre" => "Adelia" "apellidos" => "Aquilano" ] 5 => array:2 [ "nombre" => "Nesrine" "apellidos" => "Gamal" ] 6 => array:2 [ "nombre" => "Paola" "apellidos" => "Francalanci" ] 7 => array:2 [ "nombre" => "Fabio" "apellidos" => "Conti" ] 8 => array:2 [ "nombre" => "Pietro" "apellidos" => "Andreone" ] ] ] ] ] "idiomaDefecto" => "en" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1665268119306441?idApp=UINPBA00004N" "url" => "/16652681/0000001500000005/v1_201905310950/S1665268119306441/v1_201905310950/en/main.assets" ] "en" => array:12 [ "idiomaDefecto" => true "titulo" => "How to screen NAFLD patients for diabetes?" "tieneTextoCompleto" => true "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "801" "paginaFinal" => "802" ] ] "autores" => array:1 [ 0 => array:4 [ "autoresLista" => "Emmanuel I. González-Moreno, Diego García-Compean, José A. González-González, Héctor J. Maldonado-Garza" "autores" => array:4 [ 0 => array:4 [ "nombre" => "Emmanuel I." "apellidos" => "González-Moreno" "email" => array:1 [ 0 => "emmanuelgzz@meduanl.com" ] "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">*</span>" "identificador" => "cor0005" ] ] ] 1 => array:2 [ "nombre" => "Diego" "apellidos" => "García-Compean" ] 2 => array:2 [ "nombre" => "José A." "apellidos" => "González-González" ] 3 => array:2 [ "nombre" => "Héctor J." "apellidos" => "Maldonado-Garza" ] ] "afiliaciones" => array:1 [ 0 => array:2 [ "entidad" => "Gastroenterology Division. Internal Medicine Department. Hospital Universitario “Dr. José Eleuterio González”. Universidad Autónoma de Nuevo León. Monterrey, Mexico" "identificador" => "aff0005" ] ] "correspondencia" => array:1 [ 0 => array:3 [ "identificador" => "cor0005" "etiqueta" => "*" "correspondencia" => "Correspondence and reprint request:" ] ] ] ] "textoCompleto" => "<span class="elsevierStyleSections"><p id="p0005" class="elsevierStylePara elsevierViewall">Dear editor:</p><p id="p0010" class="elsevierStylePara elsevierViewall">We read with great interest the article by Fukuda, <span class="elsevierStyleItalic">et al.</span><span class="elsevierStyleSup">1</span> who found in a population-based retrospective cohort study among 4,629 participants that non-overweight individuals with non-alcoholic fatty liver disease (NAFLD) had a high risk of incident type 2 diabetes mellitus (T2DM). In developed countries NAFLD is the leading cause of chronic liver disease (CLD), as data showed that between 1988 to 1994 NAFLD accounted for 46.8% of all CLD, and between 2005 to 2008 it accounted for 75.1%.<a class="elsevierStyleCrossRef" href="#bib0010"><span class="elsevierStyleSup">2</span></a> Fukuda, <span class="elsevierStyleItalic">et al.</span><a class="elsevierStyleCrossRef" href="#bib0005"><span class="elsevierStyleSup">1</span></a> showed that the adjusted hazard ratio for incident T2DM in the non-overweight with NAFLD group was significantly higher than that in the overweight without NAFLD group (P < 0.05) as well as that in the non-overweight without NAFLD group (P < 0.01). Recently, Koehler, <span class="elsevierStyleItalic">et al.</span><a class="elsevierStyleCrossRef" href="#bib0015"><span class="elsevierStyleSup">3</span></a> not only demonstrated the important relationship between NAFLD/DM, but also illustrated that DM is closely related with the development of fibrosis. We think an important fact has not been extensively addressed; recently, it has been suggested that NAFLD patients should be screened for DM, however, there is no emphasis about which method should be used, fasting plasma glucose (FPG), glycosylated hemoglobin (HbA1c), or oral glucose tolerance test (OGTT). Fukuda, <span class="elsevierStyleItalic">et al.</span><a class="elsevierStyleCrossRef" href="#bib0005"><span class="elsevierStyleSup">1</span></a> defined T2DM according to an HbA1c ≥ 6.5% or FPG ≥ 126 mg/dL) or as the initiation of T2DM treatment. Recent evidence suggests that the best tool for screening NAFLD patients for T2DM is not FPG. In a study by Manchanayake, <span class="elsevierStyleItalic">et al.</span><a class="elsevierStyleCrossRef" href="#bib0020"><span class="elsevierStyleSup">4</span></a> 70 non-diabetic NAFLD patients underwent OGTT. One-third (34%) of patients had abnormal OGTT (24% impaired glucose tolerance and 10% DM). Importantly, only 25% of patients with abnormal OGTT had impaired FPG. Although, in this cohort, few patients had liver biopsy, those with abnormal OGTT were more likely to have cirrhosis (13%) than those with normal OGTT (4.5%). An important step in the management of NAFLD patients is to identify patients at risk to develop non-alcoholic steatohepatitis, and in this context, it seems that NAFLD patients with glucose metabolism alterations are at increased risk. Further large prospective studies should confirm if OGTT is the best way to screen NAFLD patients for DM.</p><span id="s0005" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="st0005">Abbreviations</span><p id="p0015" class="elsevierStylePara elsevierViewall"><ul class="elsevierStyleList" id="l0005"><li class="elsevierStyleListItem" id="u0005"><span class="elsevierStyleLabel">•</span><p id="p0020" class="elsevierStylePara elsevierViewall"><span class="elsevierStyleBold">CLD:</span> chronic liver disease.</p></li><li class="elsevierStyleListItem" id="u0010"><span class="elsevierStyleLabel">•</span><p id="p0025" class="elsevierStylePara elsevierViewall"><span class="elsevierStyleBold">FPG:</span> fasting blood plasma glucose.</p></li><li class="elsevierStyleListItem" id="u0015"><span class="elsevierStyleLabel">•</span><p id="p0030" class="elsevierStylePara elsevierViewall"><span class="elsevierStyleBold">NAFLD:</span> non-alcoholic fatty liver disease.</p></li><li class="elsevierStyleListItem" id="u0020"><span class="elsevierStyleLabel">•</span><p id="p0035" class="elsevierStylePara elsevierViewall"><span class="elsevierStyleBold">OGTT:</span> oral glucose tolerance test.</p></li><li class="elsevierStyleListItem" id="u0025"><span class="elsevierStyleLabel">•</span><p id="p0040" class="elsevierStylePara elsevierViewall"><span class="elsevierStyleBold">T2DM:</span> type 2 diabetes mellitus.</p></li></ul></p></span><span id="s0010" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="st0010">Conflict of Interest</span><p id="p0045" class="elsevierStylePara elsevierViewall">The authors have no conflict of interest and no financial support to disclose.</p></span></span>" "textoCompletoSecciones" => array:1 [ "secciones" => array:3 [ 0 => array:2 [ "identificador" => "s0005" "titulo" => "Abbreviations" ] 1 => array:2 [ "identificador" => "s0010" "titulo" => "Conflict of Interest" ] 2 => array:1 [ "titulo" => "References" ] ] ] "pdfFichero" => "main.pdf" "tienePdf" => true "fechaRecibido" => "2016-06-20" "fechaAceptado" => "2016-07-01" "bibliografia" => array:2 [ "titulo" => "References" "seccion" => array:1 [ 0 => array:2 [ "identificador" => "bs0010" "bibliografiaReferencia" => array:4 [ 0 => array:3 [ "identificador" => "bib0005" "etiqueta" => "1." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "The impact of non-alcoholic fatty liver disease on incident type 2 diabetes mellitus in nonoverweight individuals" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:7 [ 0 => "Fukuda T." 1 => "Hamaguchi M." 2 => "Kojima T." 3 => "Hashimoto Y." 4 => "Ohbora A." 5 => "Kato T." 6 => "Nakamura N." ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1111/liv.12912" "Revista" => array:6 [ "tituloSerie" => "Liver Int" "fecha" => "2016" "volumen" => "36" "paginaInicial" => "275" "paginaFinal" => "283" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/26176710" "web" => "Medline" ] ] ] ] ] ] ] ] 1 => array:3 [ "identificador" => "bib0010" "etiqueta" => "2." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Changes in the prevalence of the most common causes of chronic liver diseases in the United States from 1988 to 2008" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:7 [ 0 => "Younossi Z.M." 1 => "Stepanova M." 2 => "Afendy M." 3 => "Fang Y." 4 => "Younossi Y." 5 => "Mir H." 6 => "Srishord M." ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1016/j.cgh.2011.03.020" "Revista" => array:6 [ "tituloSerie" => "Clin Gastroenterol Hepatol" "fecha" => "2011" "volumen" => "9" "paginaInicial" => "524" "paginaFinal" => "530" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/21440669" "web" => "Medline" ] ] ] ] ] ] ] ] 2 => array:3 [ "identificador" => "bib0015" "etiqueta" => "3." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Presence of diabetes mellitus and steatosis is associated with liver stiffness in a general population: The Rotterdam study" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:7 [ 0 => "Koehler E.M." 1 => "Plompen E.P." 2 => "Schouten J.N." 3 => "Hansen B.E." 4 => "Darwish Murad S." 5 => "Taimr P." 6 => "Leebeek F.W." ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1002/hep.27981" "Revista" => array:6 [ "tituloSerie" => "Hepatology" "fecha" => "2016" "volumen" => "63" "paginaInicial" => "138" "paginaFinal" => "147" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/26171685" "web" => "Medline" ] ] ] ] ] ] ] ] 3 => array:3 [ "identificador" => "bib0020" "etiqueta" => "4." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Postprandial hyperinsulinemia is universal in non-diabetic patients with nonalcoholic fatty liver disease" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ 0 => "Manchanayake J." 1 => "Chitturi S." 2 => "Nolan C." 3 => "Farrell G.C." ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1111/j.1440-1746.2010.06528.x" "Revista" => array:6 [ "tituloSerie" => "J Gastroenterol Hepatol" "fecha" => "2011" "volumen" => "26" "paginaInicial" => "510" "paginaFinal" => "516" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/21155882" "web" => "Medline" ] ] ] ] ] ] ] ] ] ] ] ] ] "idiomaDefecto" => "en" "url" => "/16652681/0000001500000005/v1_201905310950/S1665268119306453/v1_201905310950/en/main.assets" "Apartado" => array:4 [ "identificador" => "77940" "tipo" => "SECCION" "en" => array:2 [ "titulo" => "Letter to Editor" "idiomaDefecto" => true ] "idiomaDefecto" => "en" ] "PDF" => "https://static.elsevier.es/multimedia/16652681/0000001500000005/v1_201905310950/S1665268119306453/v1_201905310950/en/main.pdf?idApp=UINPBA00004N&text.app=https://www.elsevier.es/" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1665268119306453?idApp=UINPBA00004N" ]
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