P- 34 HEPATOCELLULAR CARCINOMA IN CHILE; A RETROSPECTIVE MULTICENTER STUDY OF 856 PATIENTS
Blanca Norero1,3, Gonzalo Latorre1, Diego Reyes1, Carlos Benitez1, Rodrigo Wolff1,7, Marco Arrese1, Macarena Viñuela Morales1, Matias Torres Parada1, Gabriel Mezzano2, Herman Aguirre2, Javiera Busquets2, Edmundo Martinez3, Maria Elisa Tapia3, Natalia Mendoza3, Claudia Pavez4, Alexandra Ginesta4, Fernando Gomez4, Jorge Contreras4, Edgar Sanhueza4, Monserrat Rius4..., Andrea Jimenez5,10, Lorena Castro5, Javier Brahm5, Guillemo Silva5, Alvaro Urzua6, Jaime Poniachick6, Edith Contreras6, José Miguel Leiva6, Edmundo Aravena7,8, Macarena Larrain7, Nicolás Lama7, Olga Barajas8, Alejandro Ferrada9, Pauline Herman9, Pamela Yaquich11, Raúl Lazarte6,12, Rodrigo Zapata4Ver más
1 Red de Salud UC Christus, Department of Gastroenterology, Santiago, Chile
2 Hospital of Salvador, Department of Gastroenterology, Santiago, Chile
3 Dr. Sotero del Río Hospital, Department of Gastroenterology, Santiago, Chile
4 Alemana Clinic of Santiago, Department of Gastroenterology, Santiago, Chile
5 Las Condes Clinic, Department of Gastroenterology, Santiago, Chile
6 University of Chile Clinic Hospital, Gastroenterology Department, Santiago, Chile
7 San Borja Arriarán Hospital, Gastroenterology Department, Santiago, Chile
8 Arturo López Pérez Foundation, Department of Oncology, Santiago, Chile
9 Dr. Eduardo Pereira Hospital, Department of Gastroenterology, Valparaíso, Chile
10 Military Hospital of Santiago, Department of Gastroenterology, Santiago, Chile
11 San Juan de Dios Hospital, Department of Gastroenterology, Santiago, Chile
12 Dávila Clinic, Department of Gastroenterology, Santiago, Chile
Ver másRead
389
Timeswas read the article
126
Total PDF
263
Total HTML
Share statistics
array:22 [ "pii" => "S1665268123000406" "issn" => "16652681" "doi" => "10.1016/j.aohep.2023.100936" "estado" => "S300" "fechaPublicacion" => "2023-03-01" "aid" => "100904.32" "copyrightAnyo" => "2023" "documento" => "simple-article" "crossmark" => 0 "subdocumento" => "abs" "cita" => "Ann Hepatol. 2023;28 Supl 1:" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:1 [ "total" => 0 ] "itemSiguiente" => array:17 [ "pii" => "S1665268123000418" "issn" => "16652681" "doi" => "10.1016/j.aohep.2023.100937" "estado" => "S300" "fechaPublicacion" => "2023-03-01" "aid" => "100904.33" "documento" => "simple-article" "crossmark" => 0 "subdocumento" => "abs" "cita" => "Ann Hepatol. 2023;28 Supl 1:" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:1 [ "total" => 0 ] "en" => array:8 [ "idiomaDefecto" => true "titulo" => "P- 35 RELINKAGE OF PATIENTS WITH CHRONIC HEPATITIS C INFECTION IN THE CONTEXT OF THE COVID-19 PANDEMIC" "tienePdf" => "en" "tieneTextoCompleto" => 0 "tieneResumen" => "en" "contieneResumen" => array:1 [ "en" => true ] "contienePdf" => array:1 [ "en" => true ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "Gisela Fabiana Sotera, Melina Ferreiro, Margarita Martes, Cordero Nancy, Jonathan Salmon, Juan Sordá, Jorge Daruich, Esteban González Ballerga" "autores" => array:8 [ 0 => array:2 [ "nombre" => "Gisela Fabiana" "apellidos" => "Sotera" ] 1 => array:2 [ "nombre" => "Melina" "apellidos" => "Ferreiro" ] 2 => array:2 [ "nombre" => "Margarita" "apellidos" => "Martes" ] 3 => array:2 [ "nombre" => "Cordero" "apellidos" => "Nancy" ] 4 => array:2 [ "nombre" => "Jonathan" "apellidos" => "Salmon" ] 5 => array:2 [ "nombre" => "Juan" "apellidos" => "Sordá" ] 6 => array:2 [ "nombre" => "Jorge" "apellidos" => "Daruich" ] 7 => array:2 [ "nombre" => "Esteban González" "apellidos" => "Ballerga" ] ] ] ] ] "idiomaDefecto" => "en" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1665268123000418?idApp=UINPBA00004N" "url" => "/16652681/00000028000000S1/v2_202308150516/S1665268123000418/v2_202308150516/en/main.assets" ] "itemAnterior" => array:17 [ "pii" => "S166526812300039X" "issn" => "16652681" "doi" => "10.1016/j.aohep.2023.100935" "estado" => "S300" "fechaPublicacion" => "2023-03-01" "aid" => "100904.31" "documento" => "simple-article" "crossmark" => 0 "subdocumento" => "abs" "cita" => "Ann Hepatol. 2023;28 Supl 1:" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:1 [ "total" => 0 ] "en" => array:8 [ "idiomaDefecto" => true "titulo" => "P-33 IMPACT OF SUSTAINED VIROLOGIC RESPONSE ON GLUCOSE PARAMETERS AMONG CHRONIC HEPATITIS C PATIENTS TREATED WITH DIRECT ACTING ANTIVIRALS" "tienePdf" => "en" "tieneTextoCompleto" => 0 "tieneResumen" => "en" "contieneResumen" => array:1 [ "en" => true ] "contienePdf" => array:1 [ "en" => true ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "Hugo Cheinquer, Fabia Benetti, Alexandre de Araujo, Italo de Maman, Cristina Cheinquer Coelho Borges, Fernando Wolff Herz" "autores" => array:6 [ 0 => array:2 [ "nombre" => "Hugo" "apellidos" => "Cheinquer" ] 1 => array:2 [ "nombre" => "Fabia" "apellidos" => "Benetti" ] 2 => array:2 [ "nombre" => "Alexandre" "apellidos" => "de Araujo" ] 3 => array:3 [ "nombre" => "Italo" "apellidos" => "de Maman" "sufijo" => "Jr" ] 4 => array:2 [ "nombre" => "Cristina Cheinquer Coelho" "apellidos" => "Borges" ] 5 => array:2 [ "nombre" => "Fernando Wolff" "apellidos" => "Herz" ] ] ] ] ] "idiomaDefecto" => "en" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S166526812300039X?idApp=UINPBA00004N" "url" => "/16652681/00000028000000S1/v2_202308150516/S166526812300039X/v2_202308150516/en/main.assets" ] "en" => array:10 [ "idiomaDefecto" => true "titulo" => "P- 34 HEPATOCELLULAR CARCINOMA IN CHILE; A RETROSPECTIVE MULTICENTER STUDY OF 856 PATIENTS" "tieneTextoCompleto" => true "autores" => array:1 [ 0 => array:3 [ "autoresLista" => "Blanca Norero, Gonzalo Latorre, Diego Reyes, Carlos Benitez, Rodrigo Wolff, Marco Arrese, Macarena Viñuela Morales, Matias Torres Parada, Gabriel Mezzano, Herman Aguirre, Javiera Busquets, Edmundo Martinez, Maria Elisa Tapia, Natalia Mendoza, Claudia Pavez, Alexandra Ginesta, Fernando Gomez, Jorge Contreras, Edgar Sanhueza, Monserrat Rius, Andrea Jimenez, Lorena Castro, Javier Brahm, Guillemo Silva, Alvaro Urzua, Jaime Poniachick, Edith Contreras, José Miguel Leiva, Edmundo Aravena, Macarena Larrain, Nicolás Lama, Olga Barajas, Alejandro Ferrada, Pauline Herman, Pamela Yaquich, Raúl Lazarte, Rodrigo Zapata" "autores" => array:37 [ 0 => array:3 [ "nombre" => "Blanca" "apellidos" => "Norero" "referencia" => array:2 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">1</span>" "identificador" => "aff0001" ] 1 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">3</span>" "identificador" => "aff0003" ] ] ] 1 => array:3 [ "nombre" => "Gonzalo" "apellidos" => "Latorre" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">1</span>" "identificador" => "aff0001" ] ] ] 2 => array:3 [ "nombre" => "Diego" "apellidos" => "Reyes" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">1</span>" "identificador" => "aff0001" ] ] ] 3 => array:3 [ "nombre" => "Carlos" "apellidos" => "Benitez" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">1</span>" "identificador" => "aff0001" ] ] ] 4 => array:3 [ "nombre" => "Rodrigo" "apellidos" => "Wolff" "referencia" => array:2 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">1</span>" "identificador" => "aff0001" ] 1 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">7</span>" "identificador" => "aff0007" ] ] ] 5 => array:3 [ "nombre" => "Marco" "apellidos" => "Arrese" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">1</span>" "identificador" => "aff0001" ] ] ] 6 => array:3 [ "nombre" => "Macarena Viñuela" "apellidos" => "Morales" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">1</span>" "identificador" => "aff0001" ] ] ] 7 => array:3 [ "nombre" => "Matias Torres" "apellidos" => "Parada" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">1</span>" "identificador" => "aff0001" ] ] ] 8 => array:3 [ "nombre" => "Gabriel" "apellidos" => "Mezzano" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">2</span>" "identificador" => "aff0002" ] ] ] 9 => array:3 [ "nombre" => "Herman" "apellidos" => "Aguirre" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">2</span>" "identificador" => "aff0002" ] ] ] 10 => array:3 [ "nombre" => "Javiera" "apellidos" => "Busquets" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">2</span>" "identificador" => "aff0002" ] ] ] 11 => array:3 [ "nombre" => "Edmundo" "apellidos" => "Martinez" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">3</span>" "identificador" => "aff0003" ] ] ] 12 => array:3 [ "nombre" => "Maria Elisa" "apellidos" => "Tapia" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">3</span>" "identificador" => "aff0003" ] ] ] 13 => array:3 [ "nombre" => "Natalia" "apellidos" => "Mendoza" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">3</span>" "identificador" => "aff0003" ] ] ] 14 => array:3 [ "nombre" => "Claudia" "apellidos" => "Pavez" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">4</span>" "identificador" => "aff0004" ] ] ] 15 => array:3 [ "nombre" => "Alexandra" "apellidos" => "Ginesta" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">4</span>" "identificador" => "aff0004" ] ] ] 16 => array:3 [ "nombre" => "Fernando" "apellidos" => "Gomez" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">4</span>" "identificador" => "aff0004" ] ] ] 17 => array:3 [ "nombre" => "Jorge" "apellidos" => "Contreras" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">4</span>" "identificador" => "aff0004" ] ] ] 18 => array:3 [ "nombre" => "Edgar" "apellidos" => "Sanhueza" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">4</span>" "identificador" => "aff0004" ] ] ] 19 => array:3 [ "nombre" => "Monserrat" "apellidos" => "Rius" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">4</span>" "identificador" => "aff0004" ] ] ] 20 => array:3 [ "nombre" => "Andrea" "apellidos" => "Jimenez" "referencia" => array:2 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">5</span>" "identificador" => "aff0005" ] 1 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">10</span>" "identificador" => "aff0010" ] ] ] 21 => array:3 [ "nombre" => "Lorena" "apellidos" => "Castro" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">5</span>" "identificador" => "aff0005" ] ] ] 22 => array:3 [ "nombre" => "Javier" "apellidos" => "Brahm" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">5</span>" "identificador" => "aff0005" ] ] ] 23 => array:3 [ "nombre" => "Guillemo" "apellidos" => "Silva" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">5</span>" "identificador" => "aff0005" ] ] ] 24 => array:3 [ "nombre" => "Alvaro" "apellidos" => "Urzua" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">6</span>" "identificador" => "aff0006" ] ] ] 25 => array:3 [ "nombre" => "Jaime" "apellidos" => "Poniachick" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">6</span>" "identificador" => "aff0006" ] ] ] 26 => array:3 [ "nombre" => "Edith" "apellidos" => "Contreras" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">6</span>" "identificador" => "aff0006" ] ] ] 27 => array:3 [ "nombre" => "José Miguel" "apellidos" => "Leiva" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">6</span>" "identificador" => "aff0006" ] ] ] 28 => array:3 [ "nombre" => "Edmundo" "apellidos" => "Aravena" "referencia" => array:2 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">7</span>" "identificador" => "aff0007" ] 1 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">8</span>" "identificador" => "aff0008" ] ] ] 29 => array:3 [ "nombre" => "Macarena" "apellidos" => "Larrain" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">7</span>" "identificador" => "aff0007" ] ] ] 30 => array:3 [ "nombre" => "Nicolás" "apellidos" => "Lama" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">7</span>" "identificador" => "aff0007" ] ] ] 31 => array:3 [ "nombre" => "Olga" "apellidos" => "Barajas" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">8</span>" "identificador" => "aff0008" ] ] ] 32 => array:3 [ "nombre" => "Alejandro" "apellidos" => "Ferrada" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">9</span>" "identificador" => "aff0009" ] ] ] 33 => array:3 [ "nombre" => "Pauline" "apellidos" => "Herman" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">9</span>" "identificador" => "aff0009" ] ] ] 34 => array:3 [ "nombre" => "Pamela" "apellidos" => "Yaquich" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">11</span>" "identificador" => "aff0011" ] ] ] 35 => array:3 [ "nombre" => "Raúl" "apellidos" => "Lazarte" "referencia" => array:2 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">6</span>" "identificador" => "aff0006" ] 1 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">12</span>" "identificador" => "aff0012" ] ] ] 36 => array:3 [ "nombre" => "Rodrigo" "apellidos" => "Zapata" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">4</span>" "identificador" => "aff0004" ] ] ] ] "afiliaciones" => array:12 [ 0 => array:3 [ "entidad" => "Red de Salud UC Christus, Department of Gastroenterology, Santiago, Chile" "etiqueta" => "1" "identificador" => "aff0001" ] 1 => array:3 [ "entidad" => "Hospital of Salvador, Department of Gastroenterology, Santiago, Chile" "etiqueta" => "2" "identificador" => "aff0002" ] 2 => array:3 [ "entidad" => "Dr. Sotero del Río Hospital, Department of Gastroenterology, Santiago, Chile" "etiqueta" => "3" "identificador" => "aff0003" ] 3 => array:3 [ "entidad" => "Alemana Clinic of Santiago, Department of Gastroenterology, Santiago, Chile" "etiqueta" => "4" "identificador" => "aff0004" ] 4 => array:3 [ "entidad" => "Las Condes Clinic, Department of Gastroenterology, Santiago, Chile" "etiqueta" => "5" "identificador" => "aff0005" ] 5 => array:3 [ "entidad" => "University of Chile Clinic Hospital, Gastroenterology Department, Santiago, Chile" "etiqueta" => "6" "identificador" => "aff0006" ] 6 => array:3 [ "entidad" => "San Borja Arriarán Hospital, Gastroenterology Department, Santiago, Chile" "etiqueta" => "7" "identificador" => "aff0007" ] 7 => array:3 [ "entidad" => "Arturo López Pérez Foundation, Department of Oncology, Santiago, Chile" "etiqueta" => "8" "identificador" => "aff0008" ] 8 => array:3 [ "entidad" => "Dr. Eduardo Pereira Hospital, Department of Gastroenterology, Valparaíso, Chile" "etiqueta" => "9" "identificador" => "aff0009" ] 9 => array:3 [ "entidad" => "Military Hospital of Santiago, Department of Gastroenterology, Santiago, Chile" "etiqueta" => "10" "identificador" => "aff0010" ] 10 => array:3 [ "entidad" => "San Juan de Dios Hospital, Department of Gastroenterology, Santiago, Chile" "etiqueta" => "11" "identificador" => "aff0011" ] 11 => array:3 [ "entidad" => "Dávila Clinic, Department of Gastroenterology, Santiago, Chile" "etiqueta" => "12" "identificador" => "aff0012" ] ] ] ] "textoCompleto" => "<span class="elsevierStyleSections"><p id="para9001" class="elsevierStylePara elsevierViewall"><elsevierMultimedia ident="fig0001"></elsevierMultimedia></p><p id="para0005" class="elsevierStylePara elsevierViewall"><span class="elsevierStyleBold">Figure 1.</span> Global survival of HCC patients by BCLC stage (A) and Child-Pugh (CTP) (B).</p></span>" "pdfFichero" => "main.pdf" "tienePdf" => true "tieneResumen" => true "resumen" => array:1 [ "en" => array:2 [ "resumen" => "<span id="abss0001" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="cesectitle0001">Introduction and Objectives</span><p id="spara001" class="elsevierStyleSimplePara elsevierViewall">Hepatocellular carcinoma (HCC) is the third leading cause of cancer-related death worldwide. Still, there are epidemiological and clinical data in Latin America. In Chile, this is the first study regarding HCC with a significant number of patients. This study aimed to obtain and analyze clinical and epidemiological data of Chilean patients with HCC.</p></span> <span id="abss0002" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="cesectitle0002">Materials and Methods</span><p id="spara002" class="elsevierStyleSimplePara elsevierViewall">Multicenter study from 12 Chilean hospitals that have members of the Chilean Association of Hepatology as members of their staff. Clinical records from 2015-2021 were included. Kaplan-Meier survival curves and Cox regression analysis were obtained.</p></span> <span id="abss0003" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="cesectitle0003">Results</span><p id="spara003" class="elsevierStyleSimplePara elsevierViewall">We obtained data from 856 patients with HCC from 12 different centers. Median age 67 years old; 58.7% male. Cirrhosis is present in 91.2% (779) of cases. Main risk factors reported: fatty liver 47.9%(410), alcohol 19.6% (68), viral 12.2%(104) and autoimmune 3.5% (30). The median MELD score was 11.7 (CI95% 11,4-12). 38% (322) were diagnosed during surveillance; this was associated with earlier BCLC stage (OR 2,6; CI95%1,9-3,4). BCLC stages at diagnosis were 0; 8,2%(69), A: 38,5%(326), B:29,9%(253), C: 15,4%(130) and D: 8,2%(69). The main initial treatments were TACE, ablation, resection, liver transplant and sorafenib in 27,4%(226), 19,3%(159), 11,4%(94), 8%(66) and 5,5%(45), respectively. 53,4%(452) pts were in Milan Criteria at diagnosis. 9,1%(78) patients got a liver transplant. Five-year survival was 24% (CI95%20-28). The main factors associated with survival are depicted in Figure 1.</p></span> <span id="abss0004" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="cesectitle0004">Conclusions</span><p id="spara004" class="elsevierStyleSimplePara elsevierViewall">Fatty liver was remarkably the main risk factor reported for HCC in our Chilean cohort. This is a worrisome number since NAFLD is on the rise worldwide, and especially in Latin America. Surveillance is key for early detection. The liver function defined by Child-Pugh and HCC stage using BCLC staging is strongly associated with survival. Liver transplant is still a scarce treatment resource.</p></span>" "secciones" => array:4 [ 0 => array:2 [ "identificador" => "abss0001" "titulo" => "Introduction and Objectives" ] 1 => array:2 [ "identificador" => "abss0002" "titulo" => "Materials and Methods" ] 2 => array:2 [ "identificador" => "abss0003" "titulo" => "Results" ] 3 => array:2 [ "identificador" => "abss0004" "titulo" => "Conclusions" ] ] ] ] "multimedia" => array:1 [ 0 => array:6 [ "identificador" => "fig0001" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => false "mostrarDisplay" => true "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr9.jpeg" "Alto" => 483 "Ancho" => 1667 "Tamanyo" => 67363 ] ] "detalles" => array:1 [ 0 => array:3 [ "identificador" => "alt0001" "detalle" => "Unlabelled imag" "rol" => "short" ] ] ] ] ] "idiomaDefecto" => "en" "url" => "/16652681/00000028000000S1/v2_202308150516/S1665268123000406/v2_202308150516/en/main.assets" "Apartado" => null "PDF" => "https://static.elsevier.es/multimedia/16652681/00000028000000S1/v2_202308150516/S1665268123000406/v2_202308150516/en/main.pdf?idApp=UINPBA00004N&text.app=https://www.elsevier.es/" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1665268123000406?idApp=UINPBA00004N" ]
| Year/Month | Html | Total | |
|---|---|---|---|
| 2024 November | 2 | 0 | 2 |
| 2024 October | 22 | 7 | 29 |
| 2024 September | 18 | 6 | 24 |
| 2024 August | 25 | 8 | 33 |
| 2024 July | 17 | 4 | 21 |
| 2024 June | 16 | 8 | 24 |
| 2024 May | 10 | 8 | 18 |
| 2024 April | 18 | 10 | 28 |
| 2024 March | 20 | 8 | 28 |
| 2024 February | 23 | 3 | 26 |
| 2024 January | 15 | 6 | 21 |
| 2023 December | 8 | 5 | 13 |
| 2023 November | 17 | 7 | 24 |
| 2023 October | 28 | 15 | 43 |
| 2023 September | 4 | 2 | 6 |
| 2023 August | 3 | 2 | 5 |
| 2023 July | 1 | 5 | 6 |
| 2023 June | 7 | 19 | 26 |
| 2023 May | 9 | 3 | 12 |
Show all
