P- 35 RELINKAGE OF PATIENTS WITH CHRONIC HEPATITIS C INFECTION IN THE CONTEXT OF THE COVID-19 PANDEMIC
Gisela Fabiana Sotera, Melina Ferreiro, Margarita Martes, Cordero Nancy, Jonathan Salmon, Juan Sordá, Jorge Daruich, Esteban González Ballerga
Gastroenterology Division, Hepatology Section. Clinics Hospital "José de San Martín". The University of Buenos Aires. Argentina
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A RETROSPECTIVE MULTICENTER STUDY OF 856 PATIENTS" "tienePdf" => "en" "tieneTextoCompleto" => "en" "tieneResumen" => "en" "contieneResumen" => array:1 [ "en" => true ] "contieneTextoCompleto" => array:1 [ "en" => true ] "contienePdf" => array:1 [ "en" => true ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "Blanca Norero, Gonzalo Latorre, Diego Reyes, Carlos Benitez, Rodrigo Wolff, Marco Arrese, Macarena Viñuela Morales, Matias Torres Parada, Gabriel Mezzano, Herman Aguirre, Javiera Busquets, Edmundo Martinez, Maria Elisa Tapia, Natalia Mendoza, Claudia Pavez, Alexandra Ginesta, Fernando Gomez, Jorge Contreras, Edgar Sanhueza, Monserrat Rius, Andrea Jimenez, Lorena Castro, Javier Brahm, Guillemo Silva, Alvaro Urzua, Jaime Poniachick, Edith Contreras, José Miguel Leiva, Edmundo Aravena, Macarena Larrain, Nicolás Lama, Olga Barajas, Alejandro Ferrada, Pauline Herman, Pamela Yaquich, Raúl Lazarte, Rodrigo Zapata" "autores" => array:37 [ 0 => array:2 [ "nombre" => "Blanca" "apellidos" => "Norero" ] 1 => array:2 [ "nombre" => "Gonzalo" "apellidos" => "Latorre" ] 2 => array:2 [ "nombre" => "Diego" "apellidos" => "Reyes" ] 3 => array:2 [ "nombre" => "Carlos" "apellidos" => "Benitez" ] 4 => array:2 [ "nombre" => "Rodrigo" "apellidos" => "Wolff" ] 5 => array:2 [ "nombre" => "Marco" "apellidos" => "Arrese" ] 6 => array:2 [ "nombre" => "Macarena Viñuela" "apellidos" => "Morales" ] 7 => array:2 [ "nombre" => "Matias Torres" "apellidos" => "Parada" ] 8 => array:2 [ "nombre" => "Gabriel" "apellidos" => "Mezzano" ] 9 => array:2 [ "nombre" => "Herman" "apellidos" => "Aguirre" ] 10 => array:2 [ "nombre" => "Javiera" "apellidos" => "Busquets" ] 11 => array:2 [ "nombre" => "Edmundo" "apellidos" => "Martinez" ] 12 => array:2 [ "nombre" => "Maria Elisa" "apellidos" => "Tapia" ] 13 => array:2 [ "nombre" => "Natalia" "apellidos" => "Mendoza" ] 14 => array:2 [ "nombre" => "Claudia" "apellidos" => "Pavez" ] 15 => array:2 [ "nombre" => "Alexandra" "apellidos" => "Ginesta" ] 16 => array:2 [ "nombre" => "Fernando" "apellidos" => "Gomez" ] 17 => array:2 [ "nombre" => "Jorge" "apellidos" => "Contreras" ] 18 => array:2 [ "nombre" => "Edgar" "apellidos" => "Sanhueza" ] 19 => array:2 [ "nombre" => "Monserrat" "apellidos" => "Rius" ] 20 => array:2 [ "nombre" => "Andrea" "apellidos" => "Jimenez" ] 21 => array:2 [ "nombre" => "Lorena" "apellidos" => "Castro" ] 22 => array:2 [ "nombre" => "Javier" "apellidos" => "Brahm" ] 23 => array:2 [ "nombre" => "Guillemo" "apellidos" => "Silva" ] 24 => array:2 [ "nombre" => "Alvaro" "apellidos" => "Urzua" ] 25 => array:2 [ "nombre" => "Jaime" "apellidos" => "Poniachick" ] 26 => array:2 [ "nombre" => "Edith" "apellidos" => "Contreras" ] 27 => array:2 [ "nombre" => "José Miguel" "apellidos" => "Leiva" ] 28 => array:2 [ "nombre" => "Edmundo" "apellidos" => "Aravena" ] 29 => array:2 [ "nombre" => "Macarena" "apellidos" => "Larrain" ] 30 => array:2 [ "nombre" => "Nicolás" "apellidos" => "Lama" ] 31 => array:2 [ "nombre" => "Olga" "apellidos" => "Barajas" ] 32 => array:2 [ "nombre" => "Alejandro" "apellidos" => "Ferrada" ] 33 => array:2 [ "nombre" => "Pauline" "apellidos" => "Herman" ] 34 => array:2 [ "nombre" => "Pamela" "apellidos" => "Yaquich" ] 35 => array:2 [ "nombre" => "Raúl" "apellidos" => "Lazarte" ] 36 => array:2 [ "nombre" => "Rodrigo" "apellidos" => "Zapata" ] ] ] ] ] "idiomaDefecto" => "en" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1665268123000406?idApp=UINPBA00004N" "url" => "/16652681/00000028000000S1/v2_202308150516/S1665268123000406/v2_202308150516/en/main.assets" ] "en" => array:8 [ "idiomaDefecto" => true "titulo" => "P- 35 RELINKAGE OF PATIENTS WITH CHRONIC HEPATITIS C INFECTION IN THE CONTEXT OF THE COVID-19 PANDEMIC" "tieneTextoCompleto" => 0 "autores" => array:1 [ 0 => array:3 [ "autoresLista" => "Gisela Fabiana Sotera, Melina Ferreiro, Margarita Martes, Cordero Nancy, Jonathan Salmon, Juan Sordá, Jorge Daruich, Esteban González Ballerga" "autores" => array:8 [ 0 => array:2 [ "nombre" => "Gisela Fabiana" "apellidos" => "Sotera" ] 1 => array:2 [ "nombre" => "Melina" "apellidos" => "Ferreiro" ] 2 => array:2 [ "nombre" => "Margarita" "apellidos" => "Martes" ] 3 => array:2 [ "nombre" => "Cordero" "apellidos" => "Nancy" ] 4 => array:2 [ "nombre" => "Jonathan" "apellidos" => "Salmon" ] 5 => array:2 [ "nombre" => "Juan" "apellidos" => "Sordá" ] 6 => array:2 [ "nombre" => "Jorge" "apellidos" => "Daruich" ] 7 => array:2 [ "nombre" => "Esteban González" "apellidos" => "Ballerga" ] ] "afiliaciones" => array:1 [ 0 => array:2 [ "entidad" => "Gastroenterology Division, Hepatology Section. Clinics Hospital "José de San Martín". The University of Buenos Aires. Argentina" "identificador" => "aff0001" ] ] ] ] "pdfFichero" => "main.pdf" "tienePdf" => true "tieneResumen" => true "resumen" => array:1 [ "en" => array:2 [ "resumen" => "<span id="abss0001" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="cesectitle0001">Introduction and Objectives</span><p id="spara001" class="elsevierStyleSimplePara elsevierViewall">In Argentina, it is estimated that around 50% of patients infected with hepatitis C virus (HCV) have been diagnosed and only 5% of those have accessed treatment after several months; this reality got worse with the pandemic. World Health Organization proposed a global health sector strategy to eliminate HCV as a public health threat by 2030. Key elements of the elimination plan include increased diagnosis and treatment access. This study aimed to describe the implementation of “Relinkage and simplified care pathway program” as a strategy for micro-elimination of HCV.</p></span> <span id="abss0002" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="cesectitle0002">Materials and Methods</span><p id="spara002" class="elsevierStyleSimplePara elsevierViewall">: Hospital outpatients aged over 18 years, with a confirmed or suspected diagnosis of HCV infection and without follow-up during the last year, were included.  Patient selection was made by collecting data from medical records. Selected patients were contacted by telephone and scheduled for a clinic visit with a simplified care pathway. “Reflex Testing,” which is an HCV antibody test, was used; if the result was positive, an HCV RNA and genotype test on the same specimen was performed. Untreated and non-responder patients were treated.</p></span> <span id="abss0003" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="cesectitle0003">Results</span><p id="spara003" class="elsevierStyleSimplePara elsevierViewall">: A total of 938 patients were included, and 409 (44%) could be reached. Out Of these, 16.3% (67) died, 1.7% (7) developed hepatocellular carcinoma, and 6.75% (15) progressed to cirrhosis. We found that 21.7% were candidates for treatment, and the treatment was delivered in two clinic visits with an average time of 29 days (7-69). However, 41% (34) of patients with cirrhosis could not be contacted.</p></span> <span id="abss0004" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="cesectitle0004">Conclusions</span><p id="spara004" class="elsevierStyleSimplePara elsevierViewall">: Program implementation improved the diagnosis and treatment access. Furthermore, it reduces the number of clinical visits and may increase adherence to follow-up. On the other hand, we are concerned that half of the patients were lost on the follow-up and about their progression to cirrhosis rate. If we are looking for different results, we should take different measures.</p></span>" "secciones" => array:4 [ 0 => array:2 [ "identificador" => "abss0001" "titulo" => "Introduction and Objectives" ] 1 => array:2 [ "identificador" => "abss0002" "titulo" => "Materials and Methods" ] 2 => array:2 [ "identificador" => "abss0003" "titulo" => "Results" ] 3 => array:2 [ "identificador" => "abss0004" "titulo" => "Conclusions" ] ] ] ] ] "idiomaDefecto" => "en" "url" => "/16652681/00000028000000S1/v2_202308150516/S1665268123000418/v2_202308150516/en/main.assets" "Apartado" => null "PDF" => "https://static.elsevier.es/multimedia/16652681/00000028000000S1/v2_202308150516/S1665268123000418/v2_202308150516/en/main.pdf?idApp=UINPBA00004N&text.app=https://www.elsevier.es/" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1665268123000418?idApp=UINPBA00004N" ]
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