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COLOMBIA" "tienePdf" => "en" "tieneTextoCompleto" => "en" "tieneResumen" => "en" "contieneResumen" => array:1 [ "en" => true ] "contieneTextoCompleto" => array:1 [ "en" => true ] "contienePdf" => array:1 [ "en" => true ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "Jhon Edison Prieto, Anabella Clara Fantilli, María Belén Pisano, Maribel Martínez, Octavio Giayetto, Domingo Balderramo, Viviana Elizabeth Re, Robin German Prieto, José Daniel Debes, Andre Boonstra" "autores" => array:10 [ 0 => array:2 [ "nombre" => "Jhon Edison" "apellidos" => "Prieto" ] 1 => array:2 [ "nombre" => "Anabella Clara" "apellidos" => "Fantilli" ] 2 => array:2 [ "nombre" => "María Belén" "apellidos" => "Pisano" ] 3 => array:2 [ "nombre" => "Maribel" "apellidos" => "Martínez" ] 4 => array:2 [ "nombre" => "Octavio" "apellidos" => "Giayetto" ] 5 => array:2 [ "nombre" => "Domingo" "apellidos" => "Balderramo" ] 6 => array:2 [ "nombre" => "Viviana Elizabeth" "apellidos" => "Re" ] 7 => array:2 [ "nombre" => "Robin German" "apellidos" => "Prieto" ] 8 => array:2 [ "nombre" => "José Daniel" "apellidos" => "Debes" ] 9 => array:2 [ "nombre" => "Andre" "apellidos" => "Boonstra" ] ] ] ] ] "idiomaDefecto" => "en" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1665268123003289?idApp=UINPBA00004N" "url" => "/16652681/00000029000000S1/v2_202405310451/S1665268123003289/v2_202405310451/en/main.assets" ] "itemAnterior" => array:17 [ "pii" => "S1665268123003265" "issn" => "16652681" "doi" => "10.1016/j.aohep.2023.101223" "estado" => "S300" "fechaPublicacion" => "2024-02-01" "aid" => "101187.36" "documento" => "simple-article" "crossmark" => 0 "subdocumento" => "abs" "cita" => "Ann Hepatol. 2024;29 Supl 1:" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:1 [ "total" => 0 ] "en" => array:9 [ "idiomaDefecto" => true "titulo" => "P- 36 ACUTE ON CHRONIC LIVER FAILURE IN LATIN AMERICA: SUB-ANALYSIS OF A SYSTEMATIC REVIEW AND META-ANALYSIS" "tienePdf" => "en" "tieneTextoCompleto" => "en" "tieneResumen" => "en" "contieneResumen" => array:1 [ "en" => true ] "contieneTextoCompleto" => array:1 [ "en" => true ] "contienePdf" => array:1 [ "en" => true ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "Gabriel Mezzano, Herman Edgardo Aguirre, Javier Perez-Valenzuela, Aaron Cortes, Adria Juanola, Andrés Cardenas, Elsa Sola, Ruben Hernaez" "autores" => array:8 [ 0 => array:2 [ "nombre" => "Gabriel" "apellidos" => "Mezzano" ] 1 => array:2 [ "nombre" => "Herman Edgardo" "apellidos" => "Aguirre" ] 2 => array:2 [ "nombre" => "Javier" "apellidos" => "Perez-Valenzuela" ] 3 => array:2 [ "nombre" => "Aaron" "apellidos" => "Cortes" ] 4 => array:2 [ "nombre" => "Adria" "apellidos" => "Juanola" ] 5 => array:2 [ "nombre" => "Andrés" "apellidos" => "Cardenas" ] 6 => array:2 [ "nombre" => "Elsa" "apellidos" => "Sola" ] 7 => array:2 [ "nombre" => "Ruben" "apellidos" => "Hernaez" ] ] ] ] ] "idiomaDefecto" => "en" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1665268123003265?idApp=UINPBA00004N" "url" => "/16652681/00000029000000S1/v2_202405310451/S1665268123003265/v2_202405310451/en/main.assets" ] "en" => array:8 [ "idiomaDefecto" => true "titulo" => "P- 37 CLINICAL EVOLUTION OF PATIENTS WITH AUTOIMMUNE LIVER DISEASES IN A LIVER TRANSPLANTATION CENTER" "tieneTextoCompleto" => 0 "autores" => array:1 [ 0 => array:3 [ "autoresLista" => "Harlim Rodríguez, Marcia Samada, Teresita Pérez, Lisset Barroso, Zucel Danay Cruz, Kenia Yunarkis Valenzuela, Lissette Chao, Yunia Tusen, Mirta Infante" "autores" => array:9 [ 0 => array:3 [ "nombre" => "Harlim" "apellidos" => "Rodríguez" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">1</span>" "identificador" => "aff0001" ] ] ] 1 => array:3 [ "nombre" => "Marcia" "apellidos" => "Samada" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">2</span>" "identificador" => "aff0002" ] ] ] 2 => array:3 [ "nombre" => "Teresita" "apellidos" => "Pérez" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">1</span>" "identificador" => "aff0001" ] ] ] 3 => array:3 [ "nombre" => "Lisset" "apellidos" => "Barroso" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">2</span>" "identificador" => "aff0002" ] ] ] 4 => array:3 [ "nombre" => "Zucel Danay" "apellidos" => "Cruz" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">3</span>" "identificador" => "aff0003" ] ] ] 5 => array:3 [ "nombre" => "Kenia Yunarkis" "apellidos" => "Valenzuela" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">2</span>" "identificador" => "aff0002" ] ] ] 6 => array:3 [ "nombre" => "Lissette" "apellidos" => "Chao" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">2</span>" "identificador" => "aff0002" ] ] ] 7 => array:3 [ "nombre" => "Yunia" "apellidos" => "Tusen" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">2</span>" "identificador" => "aff0002" ] ] ] 8 => array:3 [ "nombre" => "Mirta" "apellidos" => "Infante" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">4</span>" "identificador" => "aff0004" ] ] ] ] "afiliaciones" => array:4 [ 0 => array:3 [ "entidad" => "Departament of Gastroenterology, General Hospital Iván Portuondo, Artemisa, Cuba" "etiqueta" => "1" "identificador" => "aff0001" ] 1 => array:3 [ "entidad" => "Departament of Gastroenterology, Surgical Medical Research Center, La Havana, Cuba" "etiqueta" => "2" "identificador" => "aff0002" ] 2 => array:3 [ "entidad" => "Departament of Gastroenterology, General Hospital Leopoldito Martínez, Mayabeque, Cuba" "etiqueta" => "3" "identificador" => "aff0003" ] 3 => array:3 [ "entidad" => "Department of Hepatology, National Institute of Gastroenterology, Havana, Cuba" "etiqueta" => "4" "identificador" => "aff0004" ] ] ] ] "pdfFichero" => "main.pdf" "tienePdf" => true "tieneResumen" => true "resumen" => array:1 [ "en" => array:2 [ "resumen" => "<span id="abss0001" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="cesectitle0001">Introduction and Objectives</span><p id="spara001" class="elsevierStyleSimplePara elsevierViewall">Autoimmune liver diseases (ALD) are entities with well-defined clinical, diagnostic and therapeutic characteristics, which share autoimmune phenomena in their pathogenesis. In their clinical evolution, when they are not controlled, they progress to cirrhosis and its complications. We aimed to describe the clinical evolution and long-term survival of patients with ALD.</p></span> <span id="abss0002" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="cesectitle0002">Materials and Methods</span><p id="spara002" class="elsevierStyleSimplePara elsevierViewall">A retrospective cohort study was carried out in 77 patients diagnosed with ALD, seen in the hepatology clinic of the Centro de Investigaciones Médico Quirúrgicas, between 2000 and 2022, with a mean follow-up of 9 years (minimum 2 and maximum of 19). The main variables were: initial stage, form of presentation, complications and clinical evolution. The data was processed with the statistical package SPSS version 19.0 on Windows, the analysis was carried out by calculating the mean, standard deviation and percentage, and for survival, the Kaplan-Meier method was used with a confidence interval of 95%.</p></span> <span id="abss0003" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="cesectitle0003">Results</span><p id="spara003" class="elsevierStyleSimplePara elsevierViewall">Of 77 patients studied, the most frequent entity was autoimmune hepatitis (AIH) (61.3%), followed by primary biliary cholangitis (PBC) (24.7%). More than half of the patients with AIH and PBC had cirrhosis at the onset of the disease, of which 14.3% had decompensated cirrhosis. In the follow-up, the majority had liver complications; ascites was the most frequent in 53.2% and the insertion of cholangiocarcinoma stood out in 45.5% of the patients with Primary sclerosing cholangitis (PSC). The progression of the disease and the need for transplantation predominated in cholestatic diseases: PBC (89.5%/57.9%) and PSC (81.8%/36.4%), while AIH was the disease with the highest survival (59%) at 10 years.</p></span> <span id="abss0004" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="cesectitle0004">Conclusions</span><p id="spara004" class="elsevierStyleSimplePara elsevierViewall">The clinical evolution of the patients with ALD was determined by the presence of the advanced stage at the time of diagnosis, which conditioned a low survival in the long-term follow-up.</p></span>" "secciones" => array:4 [ 0 => array:2 [ "identificador" => "abss0001" "titulo" => "Introduction and Objectives" ] 1 => array:2 [ "identificador" => "abss0002" "titulo" => "Materials and Methods" ] 2 => array:2 [ "identificador" => "abss0003" "titulo" => "Results" ] 3 => array:2 [ "identificador" => "abss0004" "titulo" => "Conclusions" ] ] ] ] ] "idiomaDefecto" => "en" "url" => "/16652681/00000029000000S1/v2_202405310451/S1665268123003277/v2_202405310451/en/main.assets" "Apartado" => null "PDF" => "https://static.elsevier.es/multimedia/16652681/00000029000000S1/v2_202405310451/S1665268123003277/v2_202405310451/en/main.pdf?idApp=UINPBA00004N&text.app=https://www.elsevier.es/" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1665268123003277?idApp=UINPBA00004N" ]
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