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P- 55 ACUTE LIVER FAILURE IN PERU: EPIDEMIOLOGY AND PROBLEMATIC OF SUPPORT AND MANAGEMENT
P. Martin Padilla1, Carmen Cerron1, Jaime Zegarra2, Gustavo Matias1, Mayra Galindo1, Gelsing Vásquez3, Anderson Solano4, Javier Chian5, Lorena Castro6, Catherine Peña7, Oscar Canchari8, Yessica Castillo8, Marilia Montes de Oca9, William Condori3, Pierre Azabache1, Liliana Chambi10, Angel Bardales11, Lida Castillo5, Walter Manrique11, Wilhelm Bauercordova12..., Steephany Sanchez13, Zully Placido6, Katia Acuña14, Walter Diaz7, Katherine Zevallos15, Raul Castro15, Manuel Munaico6, Juan De la Cruz16, Albel Sanchez1, Rosa Lopez1Ver más
1 Unidad de Hígado, Hospital Nacional Guillermo Almenara. EsSalud, Lima, Perú
2 UCI, Clinica Sanna San Borja, Lima, Perú
3 UCI, Instituto Materno Perinatal, MINSA, Lima, Perú
4 UCI, Hospital Ramón Castilla, EsSalud, Lima, Perú
5 UCI, Hospital de Alta Complejidad Virgen de la Puerta, EsSalud, Trujillo, Perú
6 UCI, Hospital Nacional Edgardo Rebagliati, ESalud, Lima, Perú
7 Emergencia, Hospital Central de la Policía, PNP, Lima, Perú
8 UCI, Hospital Emergencias Ate, EsSalud, Lima, Perú
9 Medicina Interna, Hospital III Iquitos, EsSalud, Puno, Perú
10 Medicina Interna, Hospital Nacional Hipólito Unanue, MINSA, Lima, Perú
11 Medicina Interna, Hospital III Daniel Alcides Carrión, MINSA, Callao, Perú
12 GastroenterologÍa, Hospital Metropolitano, EsSalud, Huanuco, Perú
13 GastroenterologÍa, Hospital Regional Docente de Cajamarca, Cajamarca, Perú
14 GastroenterologÍa, Hospital Nacional Ramiro Priale, Junin, Perú
15 Unidad de Hígado, Hospital Nacional Carlos Seguin, EsSalud, Arequipa, Perú
16 GastroenterologÍa, Hospital Belen, MINSA, Trujillo, Perú
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        "resumen" => "<span id="abss0001" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="cesectitle0001">Introduction and Objectives</span><p id="spara001" class="elsevierStyleSimplePara elsevierViewall">Acute liver failure &#40;ALF&#41; is a severe clinical entity that requires a rapid diagnosis and for its proper management requires adequate intensive care support and the possibility of liver transplantation&#46; This study aimed to show clinical epidemiological characteristics of ALF and the problematics of its management in Peru&#46;</p></span> <span id="abss0002" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="cesectitle0002">Materials and Methods</span><p id="spara002" class="elsevierStyleSimplePara elsevierViewall">Google forms electronic survey answered &#40;February-March 2023&#41; by specialists who work in hospitals that care for patients with ALF throughout Peru with the sponsorship of 3 Peruvian scientific societies&#58; intensive care &#40;SOPEMI&#41;&#44; Transplant &#40;APTOT&#41; and Hepatology &#40;APEH&#41;&#46;</p></span> <span id="abss0003" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="cesectitle0003">Results</span><p id="spara003" class="elsevierStyleSimplePara elsevierViewall">Representatives of 33 public and private hospital centers from the entire health services system responded the survey&#58; Adults&#58; 27&#47;33 &#40;81&#46;8&#37;&#41; and Pediatrics&#58; 6&#47;33 &#40;18&#46;2&#37;&#41;&#46; ALF criteria diagnosis&#58; severe acute liver injury with encephalopathy and impaired synthetic function &#40;INR &#62;&#61;1&#46;5&#41; in a patient with preexisting liver disease and with an illness &#60; 26 weeks duration&#46; Geographical regions&#58; Lima &#40;12 million inhabitants&#58; 66&#46;7&#37;&#41; and 7 other regions of Peru&#58; Arequipa&#44; La Libertad&#44; Junin&#44; Tacna&#44; Cajamarca&#44; Huanuco &#38; Puno &#40;9 million inhabitants&#58; 33&#46;3&#37;&#41;&#46; Specialties&#58; ICU&#58; 36&#46;4&#37;&#44; GI&#47;hepatology&#58; 30&#46;3&#37;&#44; emergency&#58; 15&#46;2&#37;&#44; Pediatric CU&#58; 9&#46;1&#37;&#46; Male&#47;female ratio 2-3&#47;1&#58; 57&#46;6&#37;&#46; ICU stay&#58; &#60;1 week&#58; 12&#46;1&#37;&#44; &#60;4 weeks&#58; 57&#46;6&#37;&#44; 4-8 weeks&#58; 21&#46;2&#37;&#44; &#62; 8 weeks&#58; 10&#46;1&#37;&#46; ALF Diagnostic Criteria severity&#58; MELD&#58; 54&#46;5&#37;&#46; Kings&#58; 24&#46;2&#37;&#46; Clichy&#58; 3&#37;&#46; Possibility of being transferred to a transplant center&#58; 51&#46;5&#37;&#46; ALF Mortality&#58; Multiorgan failure&#58; 90&#46;9&#37;&#46; ICU with multi-organ support&#58; 57&#46;6&#37;&#46;</p></span> <span id="abss0004" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="cesectitle0004">Conclusions</span><p id="spara004" class="elsevierStyleSimplePara elsevierViewall">ALF in Peru is a serious entity that especially affects the adult population&#44; with high mortality&#44; limited access and limited possibility of liver transplantation&#46; It is necessary to have adequate resources from the government and scientific societies &#40;SOPEMI&#44; APTOT and APEH&#41; to adequately attend this entity which requires support from human resources and adequate care from multidisciplinary health team&#46;</p></span>"
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ISSN: 16652681
Original language: English
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