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P- 56 TUBERCULOSIS IN LIVER TRANSPLANT RECIPIENTS: EXPERIENCE OF A SINGLE CENTER
Cárdenas Ramírez Bertha1, Padilla-Machaca P. Martin1,2, Cerrón Cabezas Carmen1
1 Departament of Transplant, Guillermo Almenara Hospital - EsSalud. Lima, Perú
2 University San Marcos; Lima Perú
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        "resumen" => "<span id="abss0001" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="cesectitle0001">Introduction and Objectives</span><p id="spara001" class="elsevierStyleSimplePara elsevierViewall">In Peru the tuberculosis &#40;TB&#41; is an endemic infectious disease&#46; This disease is a serious opportunistic infection in transplant recipients &#40;LTRs&#41; and has 20 to 74-fold increase in a chance of developing compared to the general population The prevalence of TB in &#40;LTRs&#41; is variable between regions&#46; This study aims to describe the rate&#44; clinics characteristics and mortality of TB in LTRs from a high-prevalence area&#46;</p></span> <span id="abss0002" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="cesectitle0002">Materials and Methods</span><p id="spara002" class="elsevierStyleSimplePara elsevierViewall">We conducted a retrospective review of liver transplant recipients with tuberculosis diagnoses at Guillermo Almenara Hospital between Mach 2001 and March 2022&#46;</p></span> <span id="abss0003" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="cesectitle0003">Results</span><p id="spara003" class="elsevierStyleSimplePara elsevierViewall">A total of 294 patients underwent LT during this period&#46; 7 &#40;2&#46;3 &#37;&#41; adult patients were diagnosed with active TB&#46; Mean age was 49 &#40;32- 64&#41; years&#59; 5 &#40;70 &#37;&#41; were males&#46; Time interval from LT to TB diagnosis was 57 months &#40;2-136&#41; and 42 &#37; had early tuberculosis &#40;&#60; 12 m&#41;&#46; Three patients had disseminated TB and Four pulmonary involvement&#46; 72 &#37; received individualized treatment to avoid hepatotoxicity related to treatment&#44; 28&#46;5&#37; had DILI with standard treatment&#46; We found 28&#46;5 &#37; mortality no related to TB infections&#46;</p></span> <span id="abss0004" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="cesectitle0004">Conclusions</span><p id="spara004" class="elsevierStyleSimplePara elsevierViewall">We observed a low rate of TB in LTRs &#40;2&#46;3&#37;&#41; from a high prevalence region&#46; Most of our patients received individualized treatment&#46;</p></span>"
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Article information
ISSN: 16652681
Original language: English
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