O-18 DIFFERENCES IN BODY COMPOSITION OF MAFLD PATIENTS ACCORDING TO BODY MASS INDEX AND METABOLIC PROFILE
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The aim of this study is to describe differences in BC in MAFLD patients.</p></span> <span id="abss0002" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="cesectitle0002">Materials and Methods</span><p id="spara002" class="elsevierStyleSimplePara elsevierViewall">Liver steatosis was evaluated by controlled attenuation parameter, patients were classified according to body mass index (BMI) and definitions of MAFLD in five groups: G1:<25kg/m2-non-MAFLD; G2: <25kg/m2-MAFLD; G3: 25-30kg/m2-MAFLD; G4:>30kg/m2-MAFLD and metabolically healthy (<3 metabolic abnormalities) (MH) and G5: >30kg/m2-MAFLD and metabolically unhealthy (MU). BC was assessed by bioelectrical impedance obtaining measurements of resistance; reactance; phase angle; percentages of fat; total body water (TBW%); intracellular and extracellular water (ICW%, ECW%) and skeletal muscle mass (SMM%). Differences in BC was analyzed by Kruskall-Wallis test. Continuous data showed as median and IQR.</p></span> <span id="abss0003" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="cesectitle0003">Results</span><p id="spara003" class="elsevierStyleSimplePara elsevierViewall">140 patients were included (G1 n=30; G2 n=24; G3 n=30; G4 n=26; G5 n=30). 56.4% (n=79) were male with median of age of 49 [41- 55] years. Overweight/obese MAFLD patients showed significant lower resistance and reactance levels (p0.05). According to vectorial analysis, chaquexia was observed in 18.4% (n=7) of patients in G4 and 15.8% (n=6) in G5 patients. Fat% was higher in patients of G5 (MU) than G2 (34.3[29.8-40.4], p=0.02) and G3 (35[31.1-38.3], p=0.01). Obese MAFLD patients showed lower TBW%, ICW% and ECW% (p0.001). (Figure). SMM% was lower in MU obese patients (29.1[26.3-31.1]) compared to healthy controls (33.4[29.3-36.8], p=0.006) and overweight patients (32[29.7-34.4], p=0.02). Phase angle did not show significant differences.</p></span> <span id="abss0004" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="cesectitle0004">Conclusions</span><p id="spara004" class="elsevierStyleSimplePara elsevierViewall">Overweight/obese MAFLD patients shows BC abnormalities in comparison with healthy controls and lean MAFLD patients. Resistance, reactance, body water and skeletal muscle mass are significant lower in both metabolically healthy/unhealthy obese patients. Changes could be explained for the sarcopenia and fat-muscle interchange and no necessary for the presence of metabolic abnormalities.</p></span>" "secciones" => array:4 [ 0 => array:2 [ "identificador" => "abss0001" "titulo" => "Introduction and Objectives" ] 1 => array:2 [ "identificador" => "abss0002" "titulo" => "Materials and Methods" ] 2 => array:2 [ "identificador" => "abss0003" "titulo" => "Results" ] 3 => array:2 [ "identificador" => "abss0004" "titulo" => "Conclusions" ] ] ] ] ] "idiomaDefecto" => "en" "url" => "/16652681/00000029000000S1/v2_202405310451/S166526812300371X/v2_202405310451/en/main.assets" "Apartado" => null "PDF" => "https://static.elsevier.es/multimedia/16652681/00000029000000S1/v2_202405310451/S166526812300371X/v2_202405310451/en/main.pdf?idApp=UINPBA00004N&text.app=https://www.elsevier.es/" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S166526812300371X?idApp=UINPBA00004N" ]
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