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Pirfenidone induces translocation of sirt1 to nucleus and deacetylation of histone 3 slows down the development of fibrosis and tumorigenicity in a experimental model of hepatocarcinoma.
Hugo C. Monroy-Ramírez1, Scarlet Arceo-Orozco1, Araceli G. Rivera-Cabral1, Marina Galicia-Moreno1, Juan Armendáriz-Borunda1,2
1 Instituto de Biología Molecular en Medicina y Terapia Génica, Centro Universitario de Ciencias de la Salud (CUCS), Universidad de Guadalajara, Guadalajara, México
2 Escuela de Medicina y Ciencias de la Salud, Tecnológico de Monterrey campus Guadalajara, Zapopan, México
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ISSN: 16652681
Original language: English
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