was read the article
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"copyrightAnyo" => "2024" "documento" => "simple-article" "crossmark" => 1 "subdocumento" => "cor" "cita" => "Ann Hepatol. 2024;29:" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:1 [ "total" => 0 ] "itemSiguiente" => array:17 [ "pii" => "S1665268124002825" "issn" => "16652681" "doi" => "10.1016/j.aohep.2024.101488" "estado" => "S300" "fechaPublicacion" => "2024-05-01" "aid" => "101488" "documento" => "simple-article" "crossmark" => 1 "subdocumento" => "cor" "cita" => "Ann Hepatol. 2024;29:" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:1 [ "total" => 0 ] "en" => array:9 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Letters to the editor</span>" "titulo" => "MASLD identifies patients with significant hepatic fibrosis and steatosis in fatty liver population" "tienePdf" => "en" "tieneTextoCompleto" => "en" "contieneTextoCompleto" => array:1 [ "en" => true ] "contienePdf" => array:1 [ "en" => true ] "resumenGrafico" => array:2 [ "original" => 0 "multimedia" => array:8 [ "identificador" => "fig0001" "etiqueta" => "Fig. 1" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr1.jpeg" "Alto" => 2459 "Ancho" => 3333 "Tamanyo" => 311476 ] ] "detalles" => array:1 [ 0 => array:3 [ "identificador" => "alt0001" "detalle" => "Fig " "rol" => "short" ] ] "descripcion" => array:1 [ "en" => "<p id="spara001" class="elsevierStyleSimplePara elsevierViewall">The characteristics of MASLD patients. (A) Venn diagram in the population with fatty liver. (B) Comparison of liver steatosis scores and fibrosis scores between MASLD and Non-MASLD steatosis patients. *** <span class="elsevierStyleItalic">p</span> < 0.001.</p>" ] ] ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "You Deng, Wenya Chen, Wen Xie" "autores" => array:3 [ 0 => array:2 [ "nombre" => "You" "apellidos" => "Deng" ] 1 => array:2 [ "nombre" => "Wenya" "apellidos" => "Chen" ] 2 => array:2 [ "nombre" => "Wen" "apellidos" => "Xie" ] ] ] ] ] "idiomaDefecto" => "en" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1665268124002825?idApp=UINPBA00004N" "url" => "/16652681/0000002900000003/v1_202404281202/S1665268124002825/v1_202404281202/en/main.assets" ] "itemAnterior" => array:18 [ "pii" => "S1665268124002801" "issn" => "16652681" "doi" => "10.1016/j.aohep.2024.101486" "estado" => "S300" "fechaPublicacion" => "2024-05-01" "aid" => "101486" "copyright" => "Fundación Clínica Médica Sur, A.C." "documento" => "simple-article" "crossmark" => 1 "subdocumento" => "cor" "cita" => "Ann Hepatol. 2024;29:" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:1 [ "total" => 0 ] "en" => array:8 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Letters to the editor</span>" "titulo" => "Impact of new fatty liver disease nomenclature on primary care— cerebration of gastroenterologists in a regional tertiary care hospital" "tienePdf" => "en" "tieneTextoCompleto" => "en" "contieneTextoCompleto" => array:1 [ "en" => true ] "contienePdf" => array:1 [ "en" => true ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "Xingcen Chen, Deliang Liu, Rong Li" "autores" => array:3 [ 0 => array:2 [ "nombre" => "Xingcen" "apellidos" => "Chen" ] 1 => array:2 [ "nombre" => "Deliang" "apellidos" => "Liu" ] 2 => array:2 [ "nombre" => "Rong" "apellidos" => "Li" ] ] ] ] ] "idiomaDefecto" => "en" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1665268124002801?idApp=UINPBA00004N" "url" => "/16652681/0000002900000003/v1_202404281202/S1665268124002801/v1_202404281202/en/main.assets" ] "en" => array:15 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Letters to the editor</span>" "titulo" => "Prevalence and mortality prognosis of steatotic liver disease phenotypes" "tieneTextoCompleto" => true "saludo" => "To the editor," "autores" => array:7 [ 0 => array:3 [ "autoresLista" => "Zhiyu Sun" "autores" => array:1 [ 0 => array:2 [ "nombre" => "Zhiyu" "apellidos" => "Sun" ] ] "afiliaciones" => array:3 [ 0 => array:2 [ "entidad" => "Department of Cardiology, the Affiliated Hospital of Qingdao University, Qingdao, Shandong, China" "identificador" => "aff0001" ] 1 => array:2 [ "entidad" => "Qingdao Municipal Key Laboratory of Hypertension (Key Laboratory of Cardiovascular Medicine), Qingdao, Shandong, China" "identificador" => "aff0002" ] 2 => array:2 [ "entidad" => "Chinese patient-oriented metabolic and ischemic risk evaluation (CREAT) study, Qingdao, Shandong, China" "identificador" => "aff0003" ] ] ] 1 => array:3 [ "autoresLista" => "Chi Zhou" "autores" => array:1 [ 0 => array:2 [ "nombre" => "Chi" "apellidos" => "Zhou" ] ] "afiliaciones" => array:2 [ 0 => array:2 [ "entidad" => "Department of Cardiology, the Affiliated Hospital of Qingdao University, Qingdao, Shandong, China" "identificador" => "aff00011" ] 1 => array:2 [ "entidad" => "Chinese patient-oriented metabolic and ischemic risk evaluation (CREAT) study, Qingdao, Shandong, China" "identificador" => "aff02003" ] ] ] 2 => array:3 [ "autoresLista" => "Yiwen Zhang" "autores" => array:1 [ 0 => array:2 [ "nombre" => "Yiwen" "apellidos" => "Zhang" ] ] "afiliaciones" => array:1 [ 0 => array:2 [ "entidad" => "Department of Endocrinology, the Affiliated Hospital of Qingdao University, Qingdao, Shandong, China" "identificador" => "aff0004" ] ] ] 3 => array:3 [ "autoresLista" => "Pengfei Li" "autores" => array:1 [ 0 => array:2 [ "nombre" => "Pengfei" "apellidos" => "Li" ] ] "afiliaciones" => array:1 [ 0 => array:2 [ "entidad" => "Department of General Practice, the Affiliated Hospital of Qingdao University, Qingdao, Shandong, China" "identificador" => "aff0005" ] ] ] 4 => array:4 [ "autoresLista" => "Junjie Guo" "autores" => array:1 [ 0 => array:4 [ "nombre" => "Junjie" "apellidos" => "Guo" "email" => array:1 [ 0 => "guojunjie@qdu.edu.cn" ] "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">*</span>" "identificador" => "cor0001" ] ] ] ] "afiliaciones" => array:3 [ 0 => array:2 [ "entidad" => "Department of Cardiology, the Affiliated Hospital of Qingdao University, Qingdao, Shandong, China" "identificador" => "aff02001" ] 1 => array:2 [ "entidad" => "Qingdao Municipal Key Laboratory of Hypertension (Key Laboratory of Cardiovascular Medicine), Qingdao, Shandong, China" "identificador" => "aff00202" ] 2 => array:2 [ "entidad" => "Chinese patient-oriented metabolic and ischemic risk evaluation (CREAT) study, Qingdao, Shandong, China" "identificador" => "aff00303" ] ] "correspondencia" => array:1 [ 0 => array:3 [ "identificador" => "cor0001" "etiqueta" => "⁎" "correspondencia" => "Corresponding author." ] ] ] 5 => array:3 [ "autoresLista" => "Zhexun Lian" "autores" => array:1 [ 0 => array:2 [ "nombre" => "Zhexun" "apellidos" => "Lian" ] ] "afiliaciones" => array:1 [ 0 => array:2 [ "entidad" => "Department of Cardiology, the Affiliated Hospital of Qingdao University, Qingdao, Shandong, China" "identificador" => "aff23001" ] ] ] 6 => array:4 [ "autoresLista" => "Hongwei Ji" "autores" => array:1 [ 0 => array:4 [ "nombre" => "Hongwei" "apellidos" => "Ji" "email" => array:1 [ 0 => "hongweijicn@tsinghua.edu.cn" ] "referencia" => array:2 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">1</span>" "identificador" => "fn1" ] 1 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">**</span>" "identificador" => "cor0002" ] ] ] ] "afiliaciones" => array:4 [ 0 => array:2 [ "entidad" => "Tsinghua Medicine, Tsinghua University, Beijing, China" "identificador" => "aff000f4" ] 1 => array:2 [ "entidad" => "Department of Cardiology, the Affiliated Hospital of Qingdao University, Qingdao, Shandong, China" "identificador" => "aff00a01" ] 2 => array:2 [ "entidad" => "Qingdao Municipal Key Laboratory of Hypertension (Key Laboratory of Cardiovascular Medicine), Qingdao, Shandong, China" "identificador" => "aff001402" ] 3 => array:2 [ "entidad" => "Chinese patient-oriented metabolic and ischemic risk evaluation (CREAT) study, Qingdao, Shandong, China" "identificador" => "aff000f3" ] ] "correspondencia" => array:1 [ 0 => array:3 [ "identificador" => "cor0002" "etiqueta" => "⁎⁎" "correspondencia" => "Corresponding author." ] ] ] ] "textoCompleto" => "<span class="elsevierStyleSections"><p id="para0003" class="elsevierStylePara elsevierViewall">We read the new nomenclature for steatotic liver disease (SLD) with great interest <a class="elsevierStyleCrossRef" href="#bib0001">[1]</a>. Given the existence of phenotypic heterogeneity of fatty liver, the extent to which these innovative SLD phenotypes (i.e., metabolic dysfunction-associated steatotic liver disease [MASLD], alcohol-related liver disease [ALD], and an overlap of the 2 [MetALD]) were associated with adverse events remains unclear.</p><p id="para0004" class="elsevierStylePara elsevierViewall">We utilized data from the Third National Health and Nutrition Examination Survey (NHANES III), which comprised data on ultrasonography-measured steatosis <a class="elsevierStyleCrossRef" href="#bib0002">[2]</a>. The ethical review board of the National Center for Health Statistics approved the implementation of NHANES. Each participant provided information on alcohol consumption through a questionnaire <a class="elsevierStyleCrossRef" href="#bib0002">[2]</a>. In NHAENS, a drink means a 12-oz beer, a 4-oz glass of wine, or an ounce of liquor, which could be converted to 14 grams of pure alcohol <a class="elsevierStyleCrossRef" href="#bib0003">[3]</a>. In this study, as suggested by the consensus <a class="elsevierStyleCrossRef" href="#bib0001">[1]</a>, MetALD patients were classified into a category distinct from MASLD to capture the pathogenic value of alcohol consumption and prognostic implications <a class="elsevierStyleCrossRef" href="#bib0001">[1]</a>. Participants were followed for the all-cause mortality by the National Death Index records were reviewed on December 31, 2019.</p><p id="para0005" class="elsevierStylePara elsevierViewall">Our analysis included 6279 participants from NHANES III who were then categorized into five groups: (1) MASLD, <span class="elsevierStyleItalic">N</span>=872, (2) MetALD, <span class="elsevierStyleItalic">N</span>=141, (3) ALD, <span class="elsevierStyleItalic">N</span>=64, (4) Other SLD, <span class="elsevierStyleItalic">N</span>=108, and (5) Participants without hepatic steatosis, <span class="elsevierStyleItalic">N</span>=5094. We used a multivariable-adjusted Cox proportional hazard regression model to assess the association of these SLD phenotypes with all-cause mortality, with models accounting for demographic and cardiometabolic risk factors. P values were 2-sided and considered significant at 0.05. All analyses were performed by using R, version 4.2.1.</p><p id="para0006" class="elsevierStylePara elsevierViewall">As shown in <a class="elsevierStyleCrossRef" href="#tbl0001">Table 1</a>, in this large and nationally representative US cohort consisting of 6279 adults (age 48.1±20, 53 % female), the prevalence of MASLD was 13.8 %, MetALD was 2.2 % and ALD was 1.0. After a median follow-up of 26.9 years, 1892 all-cause deaths were documented. We observed that ALD was significantly associated with a 69 % higher hazard of all-cause mortality (hazard ratio [95 % confidence interval], 1.69 [1.18–2.41], <span class="elsevierStyleItalic">P</span><0.001) when compared with healthy controls, while the association between other SLD phenotypes and mortality are neutral (<span class="elsevierStyleItalic">P for all</span> >0.1).</p><elsevierMultimedia ident="tbl0001"></elsevierMultimedia><p id="para0007" class="elsevierStylePara elsevierViewall">Previous studies have demonstrated the association between metabolic dysfunction associated with fatty liver disease and all-cause mortality <a class="elsevierStyleCrossRef" href="#bib0002">[2]</a>. However, as metabolic dysfunction related to fatty liver disease does not entirely exclude ALD <a class="elsevierStyleCrossRef" href="#bib0004">[4]</a>, the role of alcohol intake in SLD patients remains unclear. Our study expanded prior findings and, for the first time, showed that, for SLD patients, alcohol intake may play a more critical role than metabolic dysfunction in association with all-cause mortality. Considering that alcohol consumption was one of the leading causes of death and disability worldwide <a class="elsevierStyleCrossRef" href="#bib0005">[5]</a>. Our study further highlights the impact of alcohol consumption on mortality in SLD patients. Restricting alcohol consumption may be a crucial measure in reducing the mortality of SLD patients. The new nomenclature may provide important insights into risk stratification from an alcohol-related pathophysiological pathway. It should be noted that the population studied in the NHANES III database was examined between 1988 and 1994; the dynamic evolution of SLD during follow up was not captured in this study. More studies are warranted to validate our findings.</p><span id="sec0002" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="cesectitle0003">Author contributions</span><p id="para0009" class="elsevierStylePara elsevierViewall">HJ, ZS, JG-Conceptualization, HJ, ZS - Data curation, HJ, ZS- Formal analysis, HJ- Funding acquisition, All authors- Investigation, All authors - Methodology, JG - Project administration, JG, HJ- Resources, HJ, ZS- Software, HJ- Supervision, HJ- Validation, HJ- Visualization, All authors- Writing - original draft, All authors - Writing - review & editing.</p></span><span id="sec0003" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="cesectitle0004">Funding</span><p id="para0010" class="elsevierStylePara elsevierViewall">This study was funded in part by the <span class="elsevierStyleGrantSponsor" id="gs0001">National Natural Science Foundation of China</span> (Grant ID. <span class="elsevierStyleGrantNumber" refid="gs0001">82103908</span>), the <span class="elsevierStyleGrantSponsor" id="gs0002">Taishan Scholar Program of Shandong Province</span> (<span class="elsevierStyleGrantNumber" refid="gs0002">tsqn202211364</span>) and the Shandong Provincial Natural Science Foundation (ZR2021QH014). The funding sources had no role in the design and conduct of the study; collection, management, analysis, and interpretation of the data; preparation, review, or approval of the manuscript; and decision to submit the manuscript for publication.</p></span><span id="coi0001" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="cesectitle0005">Declaration of interests</span><p id="para0011" class="elsevierStylePara elsevierViewall">None.</p></span></span>" "textoCompletoSecciones" => array:1 [ "secciones" => array:4 [ 0 => array:2 [ "identificador" => "sec0002" "titulo" => "Author contributions" ] 1 => array:2 [ "identificador" => "sec0003" "titulo" => "Funding" ] 2 => array:2 [ "identificador" => "coi0001" "titulo" => "Declaration of interests" ] 3 => array:1 [ "titulo" => "References" ] ] ] "pdfFichero" => "main.pdf" "tienePdf" => true "fechaRecibido" => "2023-07-26" "fechaAceptado" => "2024-01-28" "NotaPie" => array:1 [ 0 => array:3 [ "etiqueta" => "1" "nota" => "<p class="elsevierStyleNotepara" id="notep0001">Last authors.</p>" "identificador" => "fn1" ] ] "multimedia" => array:1 [ 0 => array:8 [ "identificador" => "tbl0001" "etiqueta" => "Table 1" "tipo" => "MULTIMEDIATABLA" "mostrarFloat" => true "mostrarDisplay" => false "detalles" => array:1 [ 0 => array:3 [ "identificador" => "alt0001" "detalle" => "Table " "rol" => "short" ] ] "tabla" => array:3 [ "leyenda" => "<p id="spara002" class="elsevierStyleSimplePara elsevierViewall">MASLD, metabolic dysfunction-associated steatotic liver disease; ALD, alcohol-related liver disease; CI, confidence interval.</p>" "tablatextoimagen" => array:1 [ 0 => array:2 [ "tabla" => array:1 [ 0 => """ <table border="0" frame="\n \t\t\t\t\tvoid\n \t\t\t\t" class=""><thead title="thead"><tr title="table-row"><a name="en0001"></a><th class="td" title="\n \t\t\t\t\ttable-head\n \t\t\t\t " align="" valign="top" scope="col" style="border-bottom: 2px solid black"> \t\t\t\t\t\t\n \t\t\t\t\t\t</th><a name="en0002"></a><th class="td" title="\n \t\t\t\t\ttable-head\n \t\t\t\t " align="" valign="top" scope="col" style="border-bottom: 2px solid black">Overall \t\t\t\t\t\t\n \t\t\t\t\t\t</th><a name="en0003"></a><th class="td" title="\n \t\t\t\t\ttable-head\n \t\t\t\t " align="" valign="top" scope="col" style="border-bottom: 2px solid black">No Steatosis \t\t\t\t\t\t\n \t\t\t\t\t\t</th><a name="en0004"></a><th class="td" title="\n \t\t\t\t\ttable-head\n \t\t\t\t " align="" valign="top" scope="col" style="border-bottom: 2px solid black">MASLD<a class="elsevierStyleCrossRef" href="#tb1fn1">*</a> \t\t\t\t\t\t\n \t\t\t\t\t\t</th><a name="en0005"></a><th class="td" title="\n \t\t\t\t\ttable-head\n \t\t\t\t " align="" valign="top" scope="col" style="border-bottom: 2px solid black">MetALD<a class="elsevierStyleCrossRef" href="#tb1fn1">*</a> \t\t\t\t\t\t\n \t\t\t\t\t\t</th><a name="en0006"></a><th class="td" title="\n \t\t\t\t\ttable-head\n \t\t\t\t " align="" valign="top" scope="col" style="border-bottom: 2px solid black">ALD \t\t\t\t\t\t\n \t\t\t\t\t\t</th><a name="en0007"></a><th class="td" title="\n \t\t\t\t\ttable-head\n \t\t\t\t " align="" valign="top" scope="col" style="border-bottom: 2px solid black">Other SLD \t\t\t\t\t\t\n \t\t\t\t\t\t</th><a name="en0008"></a><th class="td" title="\n \t\t\t\t\ttable-head\n \t\t\t\t " align="" valign="top" scope="col" style="border-bottom: 2px solid black">P \t\t\t\t\t\t\n \t\t\t\t\t\t</th></tr></thead><tbody title="tbody"><tr title="table-row"><a name="en0009"></a><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowhead " align="" valign="top"><span class="elsevierStyleItalic">N</span> \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0010"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">6279 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0011"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">5094 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0012"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">872 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0013"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">141 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0014"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">64 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0015"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">108 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0016"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top"> \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><a name="en0017"></a><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowhead " align="" valign="top">Events, n (%) \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0018"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">1892 (30.1) \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0019"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">1472 (28.9) \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0020"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">310 (35.6) \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0021"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">67 (47.5) \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0022"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">32 (50.0) \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0023"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">11 (10.2) \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0024"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="char" valign="top"><0.001 \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><a name="en0025"></a><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_rowhead " align="" valign="top">Adjusted Hazard Ratio<a class="elsevierStyleCrossRef" href="#tb1fn2"><span class="elsevierStyleSup">#</span></a> (95% CI) \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0026"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">- \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0027"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">Reference \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0028"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">0.94 (0.82, 1.06) \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0029"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">1.19 (0.93, 1.52) \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0030"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">1.69 (1.18, 2.41) \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0031"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">0.86 (0.47, 1.56) \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0032"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="char" valign="top">0.029 \t\t\t\t\t\t\n \t\t\t\t</td></tr></tbody></table> """ ] "imagenFichero" => array:1 [ 0 => "xTab3522022.png" ] ] ] "notaPie" => array:2 [ 0 => array:3 [ "identificador" => "tb1fn1" "etiqueta" => "⁎" "nota" => "<p class="elsevierStyleNotepara" id="notep0003">The five cardiometabolic criteria evaluated as specified by Rinella <span class="elsevierStyleItalic">et al</span>. (1) Systolic blood pressure ≥ 130 mmHg or diastolic ≥ 85 mmHg, or use of antihypertensive medication. (2) Blood glucose ≥ 100 mg/dL or HbA1c ≥ 6.5%, or presence of type 2 diabetes or diabetes treatment. (3) BMI ≥ 25 or waist circumference > 94 cm (males), > 80 cm (females). (4) HDL cholesterol ≤ 40 mg/dL (males), ≤ 50 mg/dL (females), or lipid-lowering treatment. (5) Triglycerides ≥ 150 mg/dL or intake of lipid therapy.</p> <p class="elsevierStyleNotepara" id="notep0004">Other SLD represents those who had non-alcoholic SLD without metabolic dysfunction.</p>" ] 1 => array:3 [ "identificador" => "tb1fn2" "etiqueta" => "#" "nota" => "<p class="elsevierStyleNotepara" id="notep0005">Models adjusted for age, sex, current smoking, systolic blood pressure, antihypertensives, diabetes mellitus, diabetic medication, body mass index, total cholesterol, high-density lipoprotein cholesterol, lipid lowering therapy, race and family income.</p>" ] ] ] "descripcion" => array:1 [ "en" => "<p id="spara001" class="elsevierStyleSimplePara elsevierViewall">Prevalence and mortality prognosis of steatotic liver disease phenotypes.</p>" ] ] ] "bibliografia" => array:2 [ "titulo" => "References" "seccion" => array:1 [ 0 => array:2 [ "identificador" => "cebibsec1" "bibliografiaReferencia" => array:5 [ 0 => array:3 [ "identificador" => "bib0001" "etiqueta" => "[1]" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "A multi-society Delphi consensus statement on new fatty liver disease nomenclature" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "ME Rinella" 1 => "JV Lazarus" 2 => "V Ratziu" 3 => "SM Francque" 4 => "AJ Sanyal" 5 => "F Kanwal" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1016/j.jhep.2023.06.003" "Revista" => array:2 [ "tituloSerie" => "J Hepatol" "fecha" => "2023" ] ] ] ] ] ] 1 => array:3 [ "identificador" => "bib0002" "etiqueta" => "[2]" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Metabolic dysfunction-associated fatty liver disease is associated with increased all-cause mortality in the United States" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:6 [ 0 => "D Kim" 1 => "P Konyn" 2 => "KK Sandhu" 3 => "BB Dennis" 4 => "AC Cheung" 5 => "A. 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