P-5 APACHE STUDY DESIGN TO EVALUATE THE EFFICACY AND SAFETY OF PLASMA EXCHANGE WITH HUMAN SERUM ALBUMIN 5% ON SHORT-TERM SURVIVAL IN PATIENTS WITH ACUTE-ON-CHRONIC LIVER FAILURE AT HIGH RISK OF HOSPITAL MORTALITY. Nikolaos Pyrsopoulos; Giovanni Perricone; Jasmohan S. Bajaj; Thierry Gustot; Thomas Reiberger; Mireia Torres; Peter Nelson; Javier Fernandez;