P-2 NASH IS IMPROVED THROUGH MODIFICATIONS IN H3K9 METHYLATION BY PIRFENIDONE ACTING AS JMJD2B DEMETHYLASE ANTAGONIST. Samael Rodríguez; Rebeca Rosas; Angel Omar Vazquez; Ivonne Palacios; Ricardo De la Rosa; Rebeca Escutia; Josep Jiménez; Luis Felipe Jave; Arturo Santos; Ana Sandoval; Juan Armendariz;

P-21 FIBROSIS DEVELOPMENT AND MALIGNANCIES ARE DELAYED BY PIRFENIDONE WHILE INCREASING SIRT1 NUCLEAR TRANSLOCATION AND HISTONE 3 DEACETYLATIONS IN A HEPATOCARCINOMA MODEL Hugo Christian Monroy; Scarlet Arceo; Araceli Guadalupe Cabral; Marina Galicia; Juan Armendariz;

P- 25 METABOLIC, HISTOLOGICAL AND INFLAMMATORY BENEFITS IN A MURINE MODEL OF ALCOHOLIC STEATOHEPATITIS USING METHYL-GROUP DONOR SUPPLEMENTATION Carolina Diaz; Angel Omar Vázquez; Rebeca Rosas; Samael Rodriguez; Rebeca Escutia; Marina Galicia; Juan Armendariz; Ana Sandoval;