O-20 EFFECTS OF ISOCALORIC AND NEGATIVE CALORIE BALANCE EXERCISE ON SERUM LEVELS OF INSULIN-LIKE GROWTH FACTOR TYPE 1 IN SUBJECTS WITH INITIAL AND ADVANCED FATTY LIVER María Jesús Fuenzalida; Francisco Barrera; Hermann Mies; Valeria Correa; Francisca Allendes; Nancy Solis; Vanessa Oyarzún; Luis Antonio Díaz; Marco Arrese; Juan Pablo Arab; Daniel Cabrera; Felipe Contreras; Santiago Riquelme; Catterina Ferreccio; Laura Andrea Huidobro; María De Los Ángeles Spencer; Macarena Garrido; Jennifer Loyola; Paola Correa; Felipe Sobarzo; Paula Silva; Cristian Herrera; Franco Godoy;

P-16 UNLOCKING S-PINDOLOL'S POTENTIAL FOR MASLD: BENEFICIAL EFFECTS ON MUSCLE MASS AND FUNCTION AND LIVER HISTOLOGY IN WESTERN- DIET FED MICE Daniel Cabrera; Loreto Aguilar; Faride Saud; Lisbell Estrada; Marcelo Andia; Marco Arrese; Juan Pablo Arab; Luis Antonio Diaz; Francisco Barrera; Rene Baudrand; Claudio Cabello-Verrugio;

OP-7 Further exploration of differences between lean and non-lean metabolic dysfunction-associated steatotic liver disease (MASLD) in Latino subjects: PNPLA3 frequency and lipidomic profiles MARIA AYALA VALVERDE; Jorge Arnold Alvarez; Gustavo Ayares; Francisco Barrera; Daniel Cabrera; Luis Antonio Diaz; Juan Pablo Arab; Ibon Martinez-Arranz; Cristina Alonso; Jesús M. Bañales; Marco Arrese;