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Fau, S. Nabzo, V. Nasabun" "autores" => array:3 [ 0 => array:4 [ "nombre" => "C." "apellidos" => "Fau" "email" => array:1 [ 0 => "chfauf@gmail.com" ] "referencia" => array:2 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff0005" ] 1 => array:2 [ "etiqueta" => "*" "identificador" => "cor0005" ] ] ] 1 => array:3 [ "nombre" => "S." "apellidos" => "Nabzo" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff0005" ] ] ] 2 => array:3 [ "nombre" => "V." "apellidos" => "Nasabun" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">b</span>" "identificador" => "aff0010" ] ] ] ] "afiliaciones" => array:2 [ 0 => array:3 [ "entidad" => "Fundación Oftalmológica 2020, Iberoamerican Cochrane Network, Santiago, Chile" "etiqueta" => "a" "identificador" => "aff0005" ] 1 => array:3 [ "entidad" => "Universidad Andrés Bello, Santiago, Chile" "etiqueta" => "b" "identificador" => "aff0010" ] ] "correspondencia" => array:1 [ 0 => array:3 [ "identificador" => "cor0005" "etiqueta" => "⁎" "correspondencia" => "<span class="elsevierStyleItalic">Corresponding author</span>." ] ] ] ] "titulosAlternativos" => array:1 [ "es" => array:1 [ "titulo" => "Comentario al artículo: «Prevalencia de <span class="elsevierStyleItalic">Demodex</span> spp. en pestañas de una población universitaria en Santiago, Chile»" ] ] "textoCompleto" => "<span class="elsevierStyleSections"><p id="par0005" class="elsevierStylePara elsevierViewall">In the April 2020 edition of this Journal, Correa Fontt et al. published the article: “Prevalence of <span class="elsevierStyleItalic">Demodex</span> spp. in tabs of a university population in Santiago, Chile”.<a class="elsevierStyleCrossRef" href="#bib0005"><span class="elsevierStyleSup">1</span></a> The objective of this study was to establish the prevalence of <span class="elsevierStyleItalic">Demodex</span> in a population of university students. We have read and critically analyzed said article proceed to present some comments, which will allow us to read more adequately the results of this study and to value them in their right measure.</p><p id="par0010" class="elsevierStylePara elsevierViewall">The first thing that caught our attention in the article was the fact that in the title and summary the word prevalence is used, but then in the objectives this is replaced by the word presence and said term is no longer used in the rest of the article. The second comment is in relation to the methodology, in which we also found a problem: both the title and the methodology section present a sample of volunteers from a university campus. Due to the fact that participants are volunteers as opposed to being selected, the real reasons that lead a person to volunteer for a study without having been selected are not clear. This tends to bias the data and generate a problem with the representative quality of the sample.</p><p id="par0015" class="elsevierStylePara elsevierViewall">To establish the prevalence of a variable in research, it is required to selectall members of a population and evaluate them. If this is not possible mainly for reasons of cost and time (effectiveness), the option is to select a sample as representative of the population. Therefore, if this process is correct a result very similar to that of the total population is obtained, endowing the study with internal validity and the principle of representation of the results. In addition, for the results to have any value, it is necessary that they can be generalized from the sample to the population under study or to similar populations elsewhere. However, if the results cannot be generalized, they can only be applied to the sample and no one else.</p><p id="par0020" class="elsevierStylePara elsevierViewall">The success of a project depends on the way in which the sample of people participating in the study is selected. In this case, a non-probabilistic sampling, called convenience sampling, was used because it is convenient and economical in addition to having a captive sample available. However, the representative quality is very doubtful since it is not randomized, which gives rise to a serious sampling error. The author states in his study: “the University Huechuraba campus has a population of 5,147 students and 478 officials and professors, making a total of 5,625 people”. Accordingly, 200 volunteers is equivalent to 3.6% of the total population, which is a very low sampling fraction. Therefore, the way to avoid a sampling error with a reduced sample is to ensure a very good sampling technique to sustain the representative quality of the population. In this case, when deaggregating the information, the sample does not claim to contain teachers, only students and officials. In fact, 162 were students which amounted to 3.2% of the student population, and 38 civil servants which were 8% of the population of civil servants and teachers. This involves a bias of representation of teachers which were not considered in the sample, and in the case of civil servants these are over-represented and students are then under-represented. This was due to a serious sampling error, which was not to establish a sample size calculation for the study by clearly determining the necessary percentages of participants from each of the 3 groups, in addition to not using a random sampling technique, in order to obtain a representative sample of the population, in this case a simple randomised or stratified randomised sampling could be used.</p><p id="par0025" class="elsevierStylePara elsevierViewall">Finally, the authors in the statistical analysis, could have partially rectified this error by describing the results in a stratified manner, which they did not do. In addition, they carried out a statistical Mann-Whitney test obtaining a value of p<span class="elsevierStyleHsp" style=""></span>=<span class="elsevierStyleHsp" style=""></span>0.04, but they completely forgot that each statistical analysis test must fulfill some assumptions, and in the case of this test the first assumption is: “the two samples, with sizes n and m respectively, that are used for the analysis have been extracted independently and randomly from their respective populations”,<a class="elsevierStyleCrossRef" href="#bib0010"><span class="elsevierStyleSup">2</span></a> an assumption that in this case is not fulfilled.</p><p id="par0030" class="elsevierStylePara elsevierViewall">Unfortunately, this study is an example of how sampling errors, lack of calculation of sample size and lack of knowledge about the statistical test being used excludes any validity of the study because it is not a representative analysis of the university campus that was used, nor can its results be applied to other campuses or other universities.</p><p id="par0035" class="elsevierStylePara elsevierViewall">In conclusion, given that the study presents multiple methodological errors, the results should be interpreted as coming from a study with serious validity problems.</p><span id="sec0005" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0005">Funding</span><p id="par0040" class="elsevierStylePara elsevierViewall">The authors declare that they have not received any funding for this work.</p></span></span>" "textoCompletoSecciones" => array:1 [ "secciones" => array:2 [ 0 => array:2 [ "identificador" => "sec0005" "titulo" => "Funding" ] 1 => array:1 [ "titulo" => "References" ] ] ] "pdfFichero" => "main.pdf" "tienePdf" => true "NotaPie" => array:1 [ 0 => array:2 [ "etiqueta" => "☆" "nota" => "<p class="elsevierStyleNotepara" id="npar0005">Please cite this article as: Fau C, Nabzo S, Nasabun V. Comentario al artículo: «Prevalencia de <span class="elsevierStyleItalic">Demodex</span> spp. en pestañas de una población universitaria en Santiago, Chile». Arch Soc Esp Oftalmol. 2020;95:619–620.</p>" ] ] "bibliografia" => array:2 [ "titulo" => "References" "seccion" => array:1 [ 0 => array:2 [ "identificador" => "bibs0005" "bibliografiaReferencia" => array:2 [ 0 => array:3 [ "identificador" => "bib0005" "etiqueta" => "1" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Prevalence of <span class="elsevierStyleItalic">Demodex</span> spp. in eyelashes of a university’s population in Santiago, Chile" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ 0 => "J. Correa Fontt" 1 => "M. Mena Oliva" 2 => "C. Pérez Campos" 3 => "C. Alburquenque Ossandón" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1016/j.oftal.2020.01.008" "Revista" => array:6 [ "tituloSerie" => "Arch Soc Esp Oftalmol" "fecha" => "2020" "volumen" => "95" "paginaInicial" => "159" "paginaFinal" => "163" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/32067802" "web" => "Medline" ] ] ] ] ] ] ] ] 1 => array:3 [ "identificador" => "bib0010" "etiqueta" => "2" "referencia" => array:1 [ 0 => array:1 [ "referenciaCompleta" => "Wayne DW. Bioestadística. 4.ª ed, capítulo 13, Estadística no paramétrica y de libre distribución. p. 678." ] ] ] ] ] ] ] ] "idiomaDefecto" => "en" "url" => "/21735794/0000009500000012/v1_202012200623/S2173579420302073/v1_202012200623/en/main.assets" "Apartado" => array:4 [ "identificador" => "5813" "tipo" => "SECCION" "en" => array:2 [ "titulo" => "Letter to the Editor" "idiomaDefecto" => true ] "idiomaDefecto" => "en" ] "PDF" => "https://static.elsevier.es/multimedia/21735794/0000009500000012/v1_202012200623/S2173579420302073/v1_202012200623/en/main.pdf?idApp=UINPBA00004N&text.app=https://www.elsevier.es/" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2173579420302073?idApp=UINPBA00004N" ]
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Vol. 95. Issue 12.
Pages 619-620 (December 2020)
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Vol. 95. Issue 12.
Pages 619-620 (December 2020)
Letter to the Editor
Comment on: “Prevalence of Demodex spp. in eyelashes of a university's population in Santiago, Chile”
Comentario al artículo: «Prevalencia de Demodex spp. en pestañas de una población universitaria en Santiago, Chile»
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