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Inicio Archivos de la Sociedad Española de Oftalmología (English Edition) Ocular side effects of oncological therapies: Review
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Vol. 99. Issue 3.
Pages 109-132 (March 2024)
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Vol. 99. Issue 3.
Pages 109-132 (March 2024)
Review
Ocular side effects of oncological therapies: Review
Efectos secundarios oculares de las terapias oncológicas. Revisión
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2
M. Asencio-Durán
Corresponding author
masedur@hotmail.com

Corresponding author.
, E. Fernández-Gutiérrez, M. Larrañaga-Cores, C. Klein-Burgos, J.V. Dabad-Moreno, M. Capote-Díez
Servicio de Oftalmología, Hospital Universitario La Paz, Instituto de Investigación Sanitaria del Hospital La Paz (IDIPAZ), Madrid, Spain
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Tables (6)
Table 1. Overall ranking.
Table 2. Classical chemotherapy.
Table 3. Hormone therapy.
Table 4. Characteristics of the main glucocorticoids.
Table 5. Monoclonal antibodies.
Table 6. Small molecules.
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Abstract

With the advance of cancer therapy in recent years, the knowledge of the mechanisms involved in this disease has increased, which has meant an increase in the quality of life and survival of patients with tumor pathologies previously considered incurable or refractory to treatment. The number of drugs used has increased exponentially in number, and although the implicit toxicity is lower than that of conventional antineoplastic therapy, they lead to the appearance of new associated adverse effects that the ophthalmologist must recognize and manage.

Keywords:
Chemotherapy
Targeted therapy
Monoclonal antibody
Small molecules
Side effect
Resumen

Con el avance de la terapia contra el cáncer en los últimos años, ha aumentado el conocimiento de los mecanismos involucrados en esta enfermedad, lo que ha supuesto un aumento de la calidad de vida y de la supervivencia de pacientes con patologías tumorales anteriormente consideradas incurables o refractarias al tratamiento. El número de fármacos utilizados ha sufrido un aumento exponencial, y a pesar de que la toxicidad implícita es menor que la de la terapia antineoplásica convencional, conllevan la aparición de nuevos efectos adversos asociados que el oftalmólogo debe reconocer y manejar.

Palabras clave:
Quimioterapia
Terapia dirigida
Anticuerpo monoclonal
Pequeñas moléculas
Efecto secundario

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