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Inicio Archivos de la Sociedad Española de Oftalmología (English Edition) Topical tacrolimus 0.03% for the treatment of ocular psoriasis
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Vol. 91. Issue 10.
Pages 505-507 (October 2016)
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Vol. 91. Issue 10.
Pages 505-507 (October 2016)
Short communication
Topical tacrolimus 0.03% for the treatment of ocular psoriasis
Tacrolimus tópico al 0,03% en el tratamiento de la psoriasis ocular
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223
P. Rodríguez-Ausína,
Corresponding author
pazrausin@telefonica.net

Corresponding author.
, D. Antolín-Garciaa, M. Ruano del Saladob, C. Hita-Antóna
a Departamento de Oftalmología, Hospital Universitario de Torrejón, Torrejón de Ardoz, Madrid, Spain
b Departamento de Dermatología, Hospital Universitario de Torrejón, Torrejón de Ardoz, Madrid, Spain
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Abstract
Objective/methods

Cases are presented of 4 patients suffering from severe symptoms due to ocular psoriasis and who were treated with off-label 0.03% tacrolimus once a day.

Results/conclusions

All four patients had a mixed blepharitis and keratitis. Pseudopterygium and corneal opacities were present in three of them. All of them experienced an improvement of their itching and ocular surface. They all referred to a marked improvement of their quality of life in a follow-up period ranging from six months to two years. Therefore, topical tacrolimus could be considered an option in the treatment of ocular psoriasis.

Keywords:
Tacrolimus
Ocular psoriasis
Psoriasis
Blepharitis
Pseudopterygium
Resumen
Objetivo/método

Presentamos una serie de 4 pacientes afectos de psoriasis ocular con sintomatología severa, a los que se indicó tratamiento off label con tacrolimus tópico al 0,03% una vez al día.

Resultados/conclusión

La blefaritis mixta y queratitis es común a los 4, y en 3 casos hay seudopterigión y opacidades corneales. Se apreció mejoría subjetiva del prurito en 2 semanas, y al mes mejoría de la superficie. Todos manifiestan mejoría significativa de su calidad de vida tras un rango de seguimiento de 6 meses a 2 años. El tacrolimus tópico puede ser considerado una opción en el tratamiento de la psoriasis ocular.

Palabras clave:
Tacrolimus
Psoriasis ocular
Psoriasis
Blefaritis
Seudopterigión

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