Article information
Resumen
Describimos un caso de un feto malformado que presentaba una hipoplasia del timo. La autopsia se practicó después de interrupción voluntaria de la gestación por infección por el VIH-1. La madre recibía una triterapia antirretroviral y tratamiento para infecciones oportunistas.
Summary
We report an autopsy case of a malformed fetus with thymic hypoplasia. The autopsy was performed after therapeutic termination in the second trimester of pregnancy. The VIH-1 infected mother had received 3 antiviral agents and treatment for opportunistic infections.
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Bibliografía
[1.]
CJ Carpenter, MA Fischl, SM Hammer, MS Hirsch, DM Jacaobson, DA Katzenstein, et al.
Antiretroviral theraphy for VIH infection in 1996. Recomendations of an international panel.
JAMA, 27 (1996), pp. 146
[2.]
AS Fauci, C. Lane.
Enfermedad por el virus de la inmunodeficiencia humana: sida y procesos relacionados.
Interamericna, (14., pp. 2034-2107
[3.]
RM. Galbraith.
Enfermedades inmunológicas: consideraciones generales.
pp. 1073-1082
[4.]
TM Collins, RL Saltzman, Jordan M. Colin.
Infecciones virales.
(4., pp. 379-401
[5.]
Center for Disease Control and Prevention.
Update: trends in AIDS diagnosis and reporting under the expanded surveillance definition for adolescents and adults-United States 1993.
Morb Mort Week Rep, 43 (1994), pp. 826-831
[6.]
WE. Paul.
Fundamental Inmunology.
(3.,
[7.]
FS Rosen, HH Fudenberg, RA Good, W Hitzing, HG Kunkel, IM Roitt, et al.
Primary immunodeficiency disease.
N Engl J Med, 333 (1995), pp. 341-344
[8.]
MD Cooper, III AR. Lawton.
Inmunodeficiencias primarias.
(14., pp. 2024-2034
[9.]
DA Dricoll, ML Burdaf, BS. Emanuel.
A genetic etiology for Di George syndrome: consistent deletions and microdeletions of 22q11.
Am J Hum Genet, 50 (1992), pp. 924-933
[10.]
S Demczuk, A. Aurias.
Di George syndrome and related syndrome associated with 22q11. 2 delections. A review.
Am Genet, 38 (1995), pp. 59-76
[11.]
T Ohtake, S Asano, Y Nozawa, Z Uzii, H Suzuki, H. Wakasa.
Thymus aplasia in distal trisomu 14q syndrome: an autopsy case with a review of the literature.
Pathol Int, 44 (1994), pp. 151-157
[12.]
G Ostes, KH Kilburn, FP. Siegal.
Chemically induced congenital dysgenesis in the rat: a model of the Di George syndrome.
Clin Imunol Immunopathol, 28 (1983), pp. 128-134
[13.]
L Cravello, C Fredouille, MJ Jean-Pastor, JP Falco, JA. Gastaut.
Hypoplasie thymique foetale diagnostiquée après interruption de grossesse pour infection à VIH traité par trithérapie.
J Gynecol Obstet Biol Reprod, 27 (1998), pp. 533-535
[14.]
WF. Fiedman.
Congenital heart disease in infancy and childhood.
Heart disease, pp. 877-962
[15.]
WF Friedman, JS. Child.
Cardiopatías congénitas en el adulto.
Interamericana, (1998), pp. 1486-1496
[16.]
M Neufeld, N McLaren, R. Blizzard.
Autoimmune polyglandular syndromes.
Pediatr Am, 9 (1980), pp. 154-162
[17.]
DI Wilson, IE Cross, JA Goodship, J Brown, PJ Scambler, HH Bain, et al.
A prospective cytogenetic study of 36 cases of Di George syndrome.
Am J Hum Genet, 51 (1994), pp. 957-963
[18.]
Jr JT. Potts.
Enfermedades de las glándulas paratiroides y otros procesos hipercalcémicos e hipocalcémicos.
(14., pp. 2534-2557
[19.]
SI Sherman, RF. Gagel.
Trastornos que afectan a sistemas endocrinos múltiples.
Harrison. Principios de medicina interna II, 14, pp. 2423-2432
[20.]
RW Marion, AA Wiznia, RG Hutcheon, A. Rubinstein.
Human T-cell lymphotrophic virus type III (HTLV III) embriopathy: a new dysmorphism syndrom associated with intra-uterina HTLV III infection.
Am J Dis Child, 140 (1986), pp. 338-340
[21.]
S Iosub, M Bamj, RK. Stone.
More on human immunodeficiency virus embryopathy.
Pediatrics, 140 (1987), pp. 638-640
[22.]
EM Connor, RS Sperling, R. Gelber.
Reduction of maternalinfant transmission of human immunodeficiency virus type 1 with zidovudine treatment.
N Engl J Med, 331 (1994), pp. 1173-1180
[23.]
AE Pintus, S Atzeni, F Zorcolon, P Onnis, M Belloni, F Chiape, et al.
Efficacy and safett of ZVD treatment in preventing vertical transmission of VIH infections. Long term in follow-up of 22 babies born to mothers treated with ZVD [resumen]. Toulon, IXeSymposium de Sidénologie «De la virologie… à la thérapeutique».
pp. 201
[24.]
JC Pons, AM Taburet, E Singlas, JF Delfraissy, E. Papierik.
Placental passage of azathiothymidine AZT during the second trimester of pregnancy: Study by direct fetal blood sampling under ultrasound.
Eur J Obstet Gynecol Reprod biol, 40 (1991), pp. 229-231
[25.]
RS Sperling, P Stratton, MJ O’Sullivan, P Boyer, DH Watts, JS Lambert, et al.
A survey of zidovudine use in pregnant women with human immunodeficiency virus infections.
N Engl J Med, 326 (1992), pp. 887-888
[26.]
GX McLead, SM. Hammer.
Zidovudine: five years later.
Ann Intern Med, 117 (1992), pp. 487-501
[27.]
Jr HS Harpel, RF. Gautieri.
Morphine-induced fetal malformations. Encephaly and axial skeletal fusions.
J Pharma Sci, 57 (1968), pp. 1590-1597
[28.]
JE. Angel.
Methadone hydrochloride.
(38., pp. 1128-1130
[29.]
E Confino, N. Gleicher.
Abuso de drogas en el embarazo.
pp. 125-138
[30.]
V. Haygood.
Opiáceos y analgésicos sintéticos.
Medicina clínica en obstetricia, pp. 1042-1046
[31.]
RV. Lee.
Drogadicción.
Complicaciones médicas durante el embarazo, (1996), pp. 577-594
[32.]
FP Zuspan, JA Gumpel, A Meijia-Zelaya, J Madden, R. Davis.
Fetal stress from methadone withdrawal.
Am J Obstet Gynecol, 122 (1975), pp. 43-46
[33.]
SE Weinberger, ST. Weis.
Enfermedades pulmonares.
Complicaciones médicas durante el embarazo, (4., pp. 437-481
[34.]
TW Harstad, BB Little, RE Bawdon, K Knoll, D Roe, LC. Gilstrap.
Embryofetal effects of pentamidine isethionate administred to pregnant Spragne-Dawlay rats.
Am J Obstet Gynecol, 3 (1990), pp. 912-916
[35.]
J. Dormont.
Prise en charge des personnes atteintes par le VIH. Rapport 1996. París.
Flammarion, (1996), pp. 223-224
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