Effectiveness of Limberg and Karydakis flap in recurrent pilonidal sinus disease

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(A) A health control biopsy shows a uniform pattern of papillary and reticular dermis; (B) fine black elastic fibers are seen in the papillary and reticular dermis (arrows) and (C) the regular brownish color of ECM 1 expression is in the superficial epidermis and small vessels of the reticular dermis (arrows). (D and G) Lichen sclerosus exhibits upper dermal homogenization with subepidermal separation; (E) disappearance of elastic fibers were seen, whereas (E) elastic fibers in the reticular to deep dermis mostly appeared normal or showed a mild increase just beneath the hyalinized zone (arrows); (F) mild or absent brownish color of ECM 1 expression in superficial epidermis and small vessels (arrows). (H) A significant decrease in elastic fibers is present in the hyalinization zone of LS compared to control skin. (I) In addition, the hyalinization zone from LS skin presents a significant decrease of ECM 1 protein expression compared to healthy controls (p<0.001). (H&E: A, X40; D, X40; G, X100 magnification); (Resorcin: B and E X200 magnification); (ECM immunostaining: C, X200; F, X200 magnification) (Der=dermis, Epi=epidermis, Ves=vessel)." ] ] ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "Charles A.P. Godoy, Walcy R. Teodoro, Ana Paula P. Velosa, Ana Lucia Garippo, Esmeralda Miristeni Eher, Edwin Roger Parra, Mirian N. Sotto, Vera L. Capelozzi" "autores" => array:8 [ 0 => array:2 [ "nombre" => "Charles A.P." "apellidos" => "Godoy" ] 1 => array:2 [ "nombre" => "Walcy R." "apellidos" => "Teodoro" ] 2 => array:2 [ "nombre" => "Ana Paula P." "apellidos" => "Velosa" ] 3 => array:2 [ "nombre" => "Ana Lucia" "apellidos" => "Garippo" ] 4 => array:2 [ "nombre" => "Esmeralda Miristeni" "apellidos" => "Eher" ] 5 => array:2 [ "nombre" => "Edwin Roger" "apellidos" => "Parra" ] 6 => array:2 [ "nombre" => "Mirian N." "apellidos" => "Sotto" ] 7 => array:2 [ "nombre" => "Vera L." 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ULN, AST and ALT." ] ] ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "Luís Henrique Bezerra Cavalcanti Sette, Edmundo Pessoa de Almeida Lopes" "autores" => array:2 [ 0 => array:2 [ "nombre" => "Luís Henrique Bezerra Cavalcanti" "apellidos" => "Sette" ] 1 => array:2 [ "nombre" => "Edmundo Pessoa" "apellidos" => "de Almeida Lopes" ] ] ] ] ] "idiomaDefecto" => "en" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1807593222013837?idApp=UINPBA00004N" "url" => "/18075932/0000007000000005/v1_202212011403/S1807593222013837/v1_202212011403/en/main.assets" ] "en" => array:19 [ "idiomaDefecto" => true "cabecera" => "CLINICAL SCIENCE" "titulo" => "Effectiveness of Limberg and Karydakis flap in recurrent pilonidal sinus disease" "tieneTextoCompleto" => true "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "350" "paginaFinal" => "355" ] ] "autores" => array:1 [ 0 => array:4 [ "autoresLista" => "İlhan Bali, Mehmet Aziret, Selim Sözen, Seyfi Emir, Hasan Erdem, Süleyman Çetinkünar, Oktay İrkörücü" "autores" => array:7 [ 0 => array:3 [ "nombre" => "İlhan" "apellidos" => "Bali" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "I" "identificador" => "aff1" ] ] ] 1 => array:4 [ "nombre" => "Mehmet" "apellidos" => "Aziret" "email" => array:1 [ 0 => "mhmtaziret@gmail.com" ] "referencia" => array:2 [ 0 => array:2 [ "etiqueta" => "II" "identificador" => "aff2" ] 1 => array:2 [ "etiqueta" => "*" "identificador" => "cor1" ] ] ] 2 => array:3 [ "nombre" => "Selim" "apellidos" => "Sözen" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "I" "identificador" => "aff1" ] ] ] 3 => array:3 [ "nombre" => "Seyfi" "apellidos" => "Emir" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "I" "identificador" => "aff1" ] ] ] 4 => array:3 [ "nombre" => "Hasan" "apellidos" => "Erdem" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "III" "identificador" => "aff3" ] ] ] 5 => array:3 [ "nombre" => "Süleyman" "apellidos" => "Çetinkünar" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "III" "identificador" => "aff3" ] ] ] 6 => array:3 [ "nombre" => "Oktay" "apellidos" => "İrkörücü" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "II" "identificador" => "aff2" ] ] ] ] "afiliaciones" => array:3 [ 0 => array:3 [ "entidad" => "Department of General Surgery, Namık Kemal University, Tekirdağ, Turkey." "etiqueta" => "I" "identificador" => "aff1" ] 1 => array:3 [ "entidad" => "Kars State Hospital General Surgery, Kars, Merkez, Turkey." "etiqueta" => "II" "identificador" => "aff2" ] 2 => array:3 [ "entidad" => "Department of General Surgery, Adana Training and Research Hospital, Adana, Turkey." "etiqueta" => "III" "identificador" => "aff3" ] ] "correspondencia" => array:1 [ 0 => array:3 [ "identificador" => "cor1" "etiqueta" => "*" "correspondencia" => "Corresponding author:" ] ] ] ] "resumenGrafico" => array:2 [ "original" => 0 "multimedia" => array:7 [ "identificador" => "fig2" "etiqueta" => "Figure 2" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr2.jpeg" "Alto" => 284 "Ancho" => 678 "Tamanyo" => 29580 ] ] "descripcion" => array:1 [ "en" => "Limberg flap technique." ] ] ] "textoCompleto" => "INTRODUCTIONPilonidal sinus (PS) is a common disease of the natal cleft in the sacrococcygeal region with weak hair accumulation occurring in the hair follicles, which can be chronic and undergo acute exacerbation <a class="elsevierStyleCrossRefs" href="#bib1">1,2</a>. The incidence of PS is approximately 26/100,000; it is a benign disease that occurs in young men <a class="elsevierStyleCrossRefs" href="#bib3">3,4</a>.The etiology and pathogenesis of PS are not clear, although the disease is thought to be related to the accumulation of weak and lifeless hair in the intergluteal region. Over time, foreign body reaction occurs, causing abscess and sinus formation. Obesity, trauma, local irritation and a sedentary lifestyle are usually associated with PS <a class="elsevierStyleCrossRefs" href="#bib2">2,5</a>.Although pilonidal sinus can be treated using several defined conservative and surgical methods, recurrence rates remain high <a class="elsevierStyleCrossRef" href="#bib6">6</a>. Complete removal of the pilonidal sinus or sinuses and appropriate reconstruction can lead to successful recovery <a class="elsevierStyleCrossRef" href="#bib7">7</a>. However, collection of the lifeless hair depends on the anatomy of the intergluteal area, and accompanying risk factors can lead to inadequate surgery and subsequent recurrence <a class="elsevierStyleCrossRefs" href="#bib6">6,8</a>.Our aim in this study was to prospectively compare early results in patients with recurrent pilonidal sinus treated with either the Karydakis flap (KF) procedure or Limberg flap rotation (LF).MATERIALS AND METODSThis study was conducted at the surgery departments at Elazığ, Kayseri and Adana Numune Training and Research Hospitals from January 2009 to December 2013. Seventy-one patients who were treated only for recurrent pilonidal disease were eligible for the study. Patients with previous surgical procedures, including primary closure (71 cases) were considered to have recurrent disease. The 71 patients who had been treated with midline closure were divided into the following two treatment groups: the LF group (Limberg flap) and KF group (Karydakis flap). All patients were prospectively evaluated in terms of gender and age, location of sinus pits, postoperative length of hospital stay, postoperative complications (wound dehiscence, infection, hematoma, seroma and cosmetics) and recurrence. The Ethical Committee of our center approved the study protocol.Surgical procedureLimberg flap methodAll patients were operated on under spinal anesthesia in the operating room. After anesthesia, the patients were placed in the prone, jack-knife position, with the buttocks strapped apart using wide adhesive tape. Methylene blue was injected in the sinus tract using a 6-Fr feeding tube. The excision was carried down to the fascia overlying the sacrum and laterally to the fascia of the gluteus maximus muscle. Dissection was performed with electrocautery. A Limberg flap was prepared from the right or left gluteal region. A suction drain (B-VAK Wound Drainage System™, 10 Ch, Ref. 17110211, BiCakCilar, Istanbul, Turkey) was placed through a separate incision that was located 2 cm lateral from the initial incision and maintained in place until the drainage decreased to less than 10 ml/day (<a class="elsevierStyleCrossRefs" href="#fig1">Figures 1 and 2</a>).<elsevierMultimedia ident="fig1"></elsevierMultimedia><elsevierMultimedia ident="fig2"></elsevierMultimedia>Karydakis flap procedureOperations were performed under spinal anesthesia with the patient in the prone position with the buttocks strapped apart. No patient was given prophylactic antibiotics. The surgical site was shaved immediately before the operation, and the skin was prepared with povidone-iodine solution. Methylene blue was infused through the sinus to delineate the fistula tract in patients with open orifices. A Karydakis flap was created as described previously <a class="elsevierStyleCrossRefs" href="#bib2">2,4</a> (<a class="elsevierStyleCrossRefs" href="#fig1">Figures 1 and 3</a>). A suction drain (B-VAK Wound Drainage System™, 10 Ch, Ref. 17110211, Bıçakçılar, Istanbul, Turkey) was placed through a separate incision that was located 2 cm lateral from the initial incision in 17 (50 percent) patients (Group 1) and was maintained in place until the drainage decreased to less than 10 ml/day. The remaining 17 patients underwent surgery without any drain placement (Group 2). All incisions were dressed under pressure using several gauze packs and tight bandages (<a class="elsevierStyleCrossRefs" href="#fig1">Figures 1 and 3</a>).<elsevierMultimedia ident="fig3"></elsevierMultimedia>Inclusion criteriaPatients willing to give written informed consent.Presence of recurrent pilonidal sinus.Adult (over 16 years of age) undergoing surgery for recurrent pilonidal sinus.International normalizing ratio (INR) of less than 1.5.Prothrombin time (PT) of less than 15 s.Partial thromboplastin (PTT) time near normal.Platelet count greater than 50,000 per mm3 to limit the risk of bleeding.No infection at time of surgery.Exclusion criteriaPatients not willing to give informed consent.Age less than 16 years.Patient presenting with different conditions mimicking pilonidal sinus.Chronic medical conditions, such as diabetes mellitus, renal failure, or immunosuppression.Randomization criteriaIn this study, patients with recurrent pilonidal sinus were accepted who were between 16-40 years of age and were without pilonidal sinus abscess or infection.Statistical analysisStatistical analyses were performed using SPSS (Statistical Package for the Social Sciences ver. 10.0, SPSS Inc, Chicago, Illinois, USA) computer software. Student's t test was used to compare age between the groups. Complications were analyzed using the χ2 test. Parametric variables that did not exhibit normal distribution between groups were compared using the Mann-Whitney U test. Chi-square and Fisher's exact tests were used to compare categorical variables. For all statistical analyses, p<0.05 was considered significant.RESULTSIn this study, 71 patients with recurrent pilonidal disease were enrolled, of whom 37 were treated using the standard Limberg flap procedure and 34 were treated using the Karydakis flap procedure (<a class="elsevierStyleCrossRef" href="#tbl1">Table 1</a>). The two groups did not differ in age or body mass index. Similarly, the two groups did not differ significantly in terms of sinus pit location or the presence of single or multiple pits (p>0.05). The operative time was longer in the LF group. Hospitalization time was also significantly higher in the LF group than in the KF group. Most patients in the LF group were mobilized on the first postoperative day, and the median time to first mobilization was earlier in the LF group than in KF group [1 (1-1) vs. 2 (1-3) days, respectively; p<0.001]. The median duration of incapacity for work was 17 (14-20) days in KF group and 8 (6-12) days in the LF group (p<0.001) (<a class="elsevierStyleCrossRef" href="#tbl2">Table 2</a>). In KF group, eight patients had infection and four had seroma. Total wound dehiscence and flap necrosis did not occur in any patient. Seven patients had seroma with negative culture in all studied patients. Flap edema occurred in four patients in the LF group. Wound infection occurred in four patients in the LF group (<a class="elsevierStyleCrossRef" href="#tbl1">Table 1</a>). The mean time for complete healing of the wound after rhomboid excision and Limberg flap was 22.12±8.69 days. The median VAS pain score was significantly lower in the LF group (p<0.001). No recurrence occurred in any of the patients during the follow-up period. When patient satisfaction was compared, the LF group received 2.88±0.16 points and KF group received 1.43±0.44; the patients in the LF group were more satisfied in terms of aesthetics (p<0.001).<elsevierMultimedia ident="tbl1"></elsevierMultimedia><elsevierMultimedia ident="tbl2"></elsevierMultimedia>DISCUSSIONPilonidal sinus was first described by Anderson in 1847 and is often seen in the intergluteal region. This chronic disease is characterized by acute exacerbations <a class="elsevierStyleCrossRefs" href="#bib1">1-3,9</a>. PS usually occurs in healthy young men (Male/Female = 4-5/1), has a negative cosmetic appearance, and can cause loss of worktime <a class="elsevierStyleCrossRefs" href="#bib2">2-4</a>. Gurer et al. <a class="elsevierStyleCrossRef" href="#bib14">14</a> reported a mean patient age of 25.5 and a gender balance of 95% males in a series detailing the Karydakis flap procedure. In our series, the mean age was 24, and more than 95% of the patients were male.The etiology and pathogenesis of PS is frequently associated with both congenital and acquired factors. It has been suggested that PS starts as a chronic process involving the accumulation of lifeless hairs and subcutaneous hair deposition in the intergluteal region that leads to inflammation and infection <a class="elsevierStyleCrossRefs" href="#bib3">3-5</a>.Several treatment procedures have been described in the literature, ranging from simple incision and drainage to the use of complex plastic flaps for cleft obliteration. The ideal technique for the treatment of sacrococcygeal PS disease is controversial <a class="elsevierStyleCrossRefs" href="#bib2">2,5</a>. Medical treatment methods include alcohol, phenol and silver nitrate injection into the cavity. Surgical treatment methods include curettage after fistulotomy, leaving an open or marsupialized wound after cystectomy, Bascom surgery, primary excision and closure, the Karydakis flap procedure (KF), or sinus excision and skin graft and flap methods, such as Limberg flap rotation (LF). Surgical treatment is often preferred <a class="elsevierStyleCrossRefs" href="#bib8">8,11</a>.Ideally, the goals of treatment for this disease should be reliable wound healing with a low risk of recurrence, a short period of hospitalization, minimal inconvenience to the patient, and low morbidity with few wound-management problems <a class="elsevierStyleCrossRefs" href="#bib6">6,8,21</a>.Recurrence is the main problem in the treatment of pilonidal sinus. In 1970, Foss <a class="elsevierStyleCrossRef" href="#bib26">26</a> reported a collective series of 1,129 pilonidal sinus patients treated with excision and primary closure by different investigators. The failure rate of primary healing was 16%, the length of hospitalization averaged 21.7 days, and the recurrence rate was 16%. Several flap techniques have been described with recurrence rates ranging between zero and 6-8% <a class="elsevierStyleCrossRefs" href="#bib6">6-8,10-13</a>.The Karydakis flap procedure was first described by George Karydakis <a class="elsevierStyleCrossRef" href="#bib8">8</a> in 1973 and has frequently been used to treat sacrococcygeal PS. The KF achieves symmetric closure of the pilonidal wounds by avoiding placement of the wound in the midline at the depth of the natal cleft and also flattens the cleft, thereby reducing hair accumulation and mechanical irritation and decreasing recurrence <a class="elsevierStyleCrossRefs" href="#bib8">8,9,30</a>.Karydakis <a class="elsevierStyleCrossRef" href="#bib8">8</a> reported a recurrence rate of 1%, a complication rate of 8%, and a length of hospital stay of 3 days. Can et al. <a class="elsevierStyleCrossRef" href="#bib15">15</a> reported a recurrence rate of 4.6% and a complication rate of 8.9%, and Sakr et al. <a class="elsevierStyleCrossRef" href="#bib16">16</a> determined recurrence rates of 2.4% and a complication rate of 10% in their KF series. In a similar study, Sözen et al. <a class="elsevierStyleCrossRef" href="#bib17">17</a> reported a recurrence rate of 1.5% and a complication rate of 6%. In our series, no recurrence was observed in either group. In the KF group, the complication rate was 10%, and the mean duration of hospital stay was 3 days.Wound infection, fluid collection, edema, hematoma and wound separation can occur after use of the Karydakis flap procedure and other surgical techniques. The use of drains after surgery can be used to prevent fluid accumulation, edema and hematoma formation in such cases <a class="elsevierStyleCrossRefs" href="#bib14">14,17</a>. Gurer et al. <a class="elsevierStyleCrossRef" href="#bib14">14</a> reported that fluid accumulation is reduced after the routine use of post-operative drains. Bessa <a class="elsevierStyleCrossRef" href="#bib18">18</a> determined that the percentage of cases with fluid retention after drain placement was 2.4%. In our KF group, 5.6% of patients experienced fluid collection, 11% experienced wound infection, and 1.4% experienced hematoma. In contrast, in the LF group, 4.2% of patients experienced fluid collection, 5.6% experienced wound infection, and 11% experienced hematoma.The LF and KF procedures not only cover the wound but also, in theory, flatten the natal cleft and decrease hair accumulation, mechanical irritation and the risk of recurrence <a class="elsevierStyleCrossRefs" href="#bib2">2,11</a>.Limberg flap rotation is clearly preferred for safety reasons given its low recurrence and complication rates <a class="elsevierStyleCrossRef" href="#bib19">19</a>. In patients with recurrence and multiple sinuses, lateral flap rotations are implemented by removing the midline <a class="elsevierStyleCrossRefs" href="#bib6">6,19</a>.Mentes et al. <a class="elsevierStyleCrossRef" href="#bib20">20</a>, Ersoy et al. <a class="elsevierStyleCrossRef" href="#bib21">21</a>, and Campbell et al. <a class="elsevierStyleCrossRef" href="#bib22">22</a> reported that modified Limberg flaps presented lower recurrence and complication rates than KF in their respective series. The reported recurrence rate for Limberg flap varies from 0.8 to 2.7% <a class="elsevierStyleCrossRef" href="#bib21">21</a>. Topgul et al. <a class="elsevierStyleCrossRef" href="#bib27">27</a> operated on 200 patients, and the recurrence rate was found to be 2.5%. Daphan et al. <a class="elsevierStyleCrossRef" href="#bib28">28</a> operated on 147 patients with a median follow-up time of 13.1 months, and recurrence was noted in 4.8% of patients.Ertan et al. <a class="elsevierStyleCrossRef" href="#bib23">23</a> reported that a Limberg flap recurrence rate of 2% compared to 12% in a primary closure group. Conversely, Ateş et al. <a class="elsevierStyleCrossRef" href="#bib24">24</a> reported lower recurrence and complication rates for the KF technique than for the LF technique. The mean duration of hospital discharge after Limberg flap procedure reported by Urhan et al. <a class="elsevierStyleCrossRef" href="#bib6">6</a> was 3.7 days, and Kapan et al. <a class="elsevierStyleCrossRef" href="#bib19">19</a> reported a duration of 5.3 days.In our study, recurrence was not observed in either group; in addition, time to discharge from hospital and complication rates were similar to values reported in the literature. The Limberg flap group had lower mean time to hospital discharge (LF/KF=3/1, 4 days) (p=0.001) and lower wound infection rates (p=0.001) than the KF group. In addition, comparison of the two groups showed a difference in terms of flap edema and hematoma (p=0.017 and p=0.004, respectively).A Cochrane overview has been performed to provide evidence-based guidance for surgical treatment <a class="elsevierStyleCrossRef" href="#bib3">3</a>. The review concluded that off-midline closure (including rhomboid, Karydakis and Bascom flaps) is the best choice if the sinus is to be excised and sutured, and this closure is associated with shorter hospital stay and the lowest recurrence rates <a class="elsevierStyleCrossRef" href="#bib29">29</a>.Other important points in the treatment of pilonidal sinus surgery are return to daily activities and work, postoperative pain score (VAS), duration of operation, time sitting on the toilet, and patient aesthetic satisfaction. In patients with recurrence and large defects, undergoing flap procedures can reduce aesthetic satisfaction. Akinci et al. <a class="elsevierStyleCrossRef" href="#bib4">4</a> reported that return to daily activities after the Karydakis flap procedure was 12.4 to 20 days and that postoperative patient satisfaction was high.Can et al. <a class="elsevierStyleCrossRef" href="#bib15">15</a> reported 70% patient satisfaction after the Karydakis flap procedure, and a recent study reported satisfaction as high as 91%. Can et al. <a class="elsevierStyleCrossRef" href="#bib15">15</a> and Ersoy et al. <a class="elsevierStyleCrossRef" href="#bib21">21</a> determined that patients undergoing the Karydakis flap procedure and LF experience similar durations of hospital stay and return to work times. Karaca et al.<a class="elsevierStyleCrossRef" href="#bib25">25</a> reported that the Limberg Flap group provided better postoperative pain score (visual analogue scale: VAS), complication rate, time to discontinuation of analgesics, and painless sitting than the KF group, and Ersoy et al. <a class="elsevierStyleCrossRef" href="#bib21">21</a> found similar results. Can et al. <a class="elsevierStyleCrossRef" href="#bib15">15</a> showed that mean operation time for the Karydakis flap procedure was 49±7 minutes, compared with 52±5 minutes for the Limberg flap procedure. In our study, the LF group exhibited a lower VAS score (2/4), higher patient satisfaction (2.8/1.43), earlier first mobilization (1/2 days) and more painless toilet sitting. (1/2 day). These patients also had shorter complete healing time (22/24 day) than the KF group (p≤0.001). On the other hand, the KF group had a shorter operation time than the LF group (48 and 54 minutes, respectively) (p=0.001).The Limberg flap procedure is a safe choice for the surgical treatment of sacrococcygeal recurrent pilonidal sinus disease due to its low complication rate, short length of hospital stay, early return work, low VAS score, high patient satisfaction and shorter complete healing duration. Therefore, we recommend the Limberg flap procedure for the treatment of recurrent pilonidal sinus disease.AUTHOR CONTRIBUTIONSBali İ participated in the project design and execution, experimental practical work, data collection, transcription and coordination. Aziret M participated in the project design and execution, experimental practical work and data collection. Sözen S and Çetinkünar S participated in the project design, execution and experimental work. Emir S and Erdem H collected the data and performed the statistical analysis. İrkörücü O participated in the project design and data collection." "textoCompletoSecciones" => array:1 [ "secciones" => array:7 [ 0 => array:2 [ "identificador" => "xpalclavsec1582300" "titulo" => "KEYWORDS" ] 1 => array:2 [ "identificador" => "cesec10" "titulo" => "INTRODUCTION" ] 2 => array:3 [ "identificador" => "cesec20" "titulo" => "MATERIALS AND METODS" "secciones" => array:5 [ 0 => array:3 [ "identificador" => "cesec30" "titulo" => "Surgical procedure" "secciones" => array:2 [ 0 => array:2 [ "identificador" => "cesec40" "titulo" => "Limberg flap method" ] 1 => array:2 [ "identificador" => "cesec50" "titulo" => "Karydakis flap procedure" ] ] ] 1 => array:2 [ "identificador" => "cesec60" "titulo" => "Inclusion criteria" ] 2 => array:2 [ "identificador" => "cesec70" "titulo" => "Exclusion criteria" ] 3 => array:2 [ "identificador" => "cesec80" "titulo" => "Randomization criteria" ] 4 => array:2 [ "identificador" => "cesec90" "titulo" => "Statistical analysis" ] ] ] 3 => array:2 [ "identificador" => "cesec100" "titulo" => "RESULTS" ] 4 => array:2 [ "identificador" => "cesec110" "titulo" => "DISCUSSION" ] 5 => array:2 [ "identificador" => "cesec120" "titulo" => "AUTHOR CONTRIBUTIONS" ] 6 => array:1 [ "titulo" => "REFERENCES" ] ] ] "pdfFichero" => "main.pdf" "tienePdf" => true "fechaRecibido" => "2014-11-10" "fechaAceptado" => "2015-02-13" "PalabrasClave" => array:1 [ "en" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "KEYWORDS" "identificador" => "xpalclavsec1582300" "palabras" => array:3 [ 0 => "Karydakis flap" 1 => "Limberg technique" 2 => "Recurrent pilonidal sinus" ] ] ] ] "tieneResumen" => true "resumen" => array:1 [ "en" => array:2 [ "resumen" => "OBJECTIVE:Sacrococcygeal pilonidal sinus is common in young men and may recur over time after surgery. We investigated whether a factor exists that can aid in the determination of the preferred technique between the early Limberg flap and Karydakis flap techniques for treating recurrent pilonidal sinus. MATERIALS AND METHODS:This prospective and randomized study enrolled 71 patients with recurrent pilonidal sinus in whom the Limberg flap or Karydakis flap techniques were applied for reconstruction after excision. Patients were divided into two groups as follows: 37 patients were treated with the Limberg flap technique and 34 patients were treated with the Karydakis flap technique. Fluid collection, wound infection, flap edema, hematoma, partial wound separation, return to daily activities, pain score, complete healing time, painless seating and patient satisfaction were compared between the groups. ClinicalTrial.gov: NCT02287935. RESULTS:The development rates of total fluid collection, wound infection, flap edema, hematoma, and partial wound separation were 9.8%, 16%, 7%, 15% and 4.2%, respectively; total flap necrosis was not observed in any patient (p<0.001). During the average follow-up of 28 months, no patients (0%) developed recurrent disease. The two groups differed with respect to early surgical complications (p<0.001). CONCLUSION:In this study, use of the Limberg flap was associated with lower complication rates, shorter length of hospital stay, early return to work, low pain score, high patient satisfaction and better complete healing duration. Therefore, we recommend the Limberg flap for treatment of recurrent pilonidal sinus." "secciones" => array:4 [ 0 => array:2 [ "identificador" => "ceabs10" "titulo" => "OBJECTIVE:" ] 1 => array:2 [ "identificador" => "ceabs20" "titulo" => "MATERIALS AND METHODS:" ] 2 => array:2 [ "identificador" => "ceabs30" "titulo" => "RESULTS:" ] 3 => array:2 [ "identificador" => "ceabs40" "titulo" => "CONCLUSION:" ] ] ] ] "NotaPie" => array:1 [ 0 => array:1 [ "nota" => "No potential conflict of interest was reported." ] ] "multimedia" => array:5 [ 0 => array:7 [ "identificador" => "fig1" "etiqueta" => "Figure 1" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr1.jpeg" "Alto" => 451 "Ancho" => 754 "Tamanyo" => 30069 ] ] "descripcion" => array:1 [ "en" => "Asymmetric elliptical excision (1A). Closure of the cavity with Karydakis flap (1B). Rhomboid excision (2A). Limberg flap and construction after rhomboid excision (2B)." ] ] 1 => array:7 [ "identificador" => "fig2" "etiqueta" => "Figure 2" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr2.jpeg" "Alto" => 284 "Ancho" => 678 "Tamanyo" => 29580 ] ] "descripcion" => array:1 [ "en" => "Limberg flap technique." ] ] 2 => array:7 [ "identificador" => "fig3" "etiqueta" => "Figure 3" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr3.jpeg" "Alto" => 332 "Ancho" => 691 "Tamanyo" => 36230 ] ] "descripcion" => array:1 [ "en" => "Karydakis flap rotation." ] ] 3 => array:7 [ "identificador" => "tbl1" "etiqueta" => "Table 1" "tipo" => "MULTIMEDIATABLA" "mostrarFloat" => true "mostrarDisplay" => false "tabla" => array:1 [ "tablatextoimagen" => array:1 [ 0 => array:1 [ "tabla" => array:1 [ 0 => """ <table border="0" frame="\n \t\t\t\t\tvoid\n \t\t\t\t" class=""><thead title="thead"><tr title="table-row"><th class="td" title="\n \t\t\t\t\ttable-head\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t" scope="col">Variable \t\t\t\t\t\t\n \t\t\t\t\t\t</th><th class="td" title="\n \t\t\t\t\ttable-head\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t" scope="col">Limberg Flap \t\t\t\t\t\t\n \t\t\t\t\t\t</th><th class="td" title="\n \t\t\t\t\ttable-head\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t" scope="col">Karydakis Flap \t\t\t\t\t\t\n \t\t\t\t\t\t</th><th class="td" title="\n \t\t\t\t\ttable-head\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t" scope="col">p-value \t\t\t\t\t\t\n \t\t\t\t\t\t</th></tr></thead><tbody title="tbody"><tr title="table-row"><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">Gender (M/F) \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">32/5 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">32/2 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">0.650 \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">Age (years) \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">25 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">23.5 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">0.21 \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">Location \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t"> \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t"> \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t"> \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">Midline single \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">18 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">22 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">0.55 \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">Midline multiple \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">14 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">10 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t"> \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">Hirsute Nature \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">24 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">22 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">0.831 \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">History of Smoking \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">14 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">12 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">0.54 \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">Duration of preoperative complaints (months) \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">14.32±10.12 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">12.66±4.43 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">0.08 \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">Length of hospital stay (days) \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">1.44 (1-3) \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">3 (3-6) \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">0.001 \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">Obesity \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t"> \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t"> \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t"> \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">Overweight (BMI 25-29.9) \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">22 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">18 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">0.455 \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">Obese (BMI 30-39.9) \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">13 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">14 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t"> \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">Morbidly obese (BMI ≥ 40) \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">3 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">2 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t"> \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">Follow up (months) \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">28.2±7.65 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">27.6±8.32 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">0.750 \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">Fluid collection \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">3 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">4 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">0.82 \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">Wound infection \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">4 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">8 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">0.001 \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">Flap edema \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">4 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">1 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">0.017 \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">Hematoma \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">8 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">3 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">0.004 \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">Partial wound dehiscence \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">1 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">2 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">0.590 \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">Recurrence \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">0 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">0 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t"> \t\t\t\t\t\t\n \t\t\t\t</td></tr></tbody></table> """ ] ] ] ] "descripcion" => array:1 [ "en" => "Clinical comparison, operative characteristics and complications between groups." ] ] 4 => array:7 [ "identificador" => "tbl2" "etiqueta" => "Table 2" "tipo" => "MULTIMEDIATABLA" "mostrarFloat" => true "mostrarDisplay" => false "tabla" => array:1 [ "tablatextoimagen" => array:1 [ 0 => array:1 [ "tabla" => array:1 [ 0 => """ <table border="0" frame="\n \t\t\t\t\tvoid\n \t\t\t\t" class=""><thead title="thead"><tr title="table-row"><th class="td" title="\n \t\t\t\t\ttable-head\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t" scope="col">Variable \t\t\t\t\t\t\n \t\t\t\t\t\t</th><th class="td" title="\n \t\t\t\t\ttable-head\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t" scope="col">Limberg Flap group \t\t\t\t\t\t\n \t\t\t\t\t\t</th><th class="td" title="\n \t\t\t\t\ttable-head\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t" scope="col">Karydakis Flap group \t\t\t\t\t\t\n \t\t\t\t\t\t</th><th class="td" title="\n \t\t\t\t\ttable-head\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t" scope="col">p-value \t\t\t\t\t\t\n \t\t\t\t\t\t</th></tr></thead><tbody title="tbody"><tr title="table-row"><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">Duration of operation (min) \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">54 (50-70) \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">48 (40-60) \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">0.001 \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">Time to first mobilization (days) \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">1 (1-1) \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">2 (1-3) \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t"><0.001 \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">Duration of incapacity for work \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">8 (6-12) \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">17 (14-20) \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t"><0.001 \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">Pain VAS score \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">2 (1-3) \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">4 (2-6) \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t"><0.001 \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">Complete healing time (days) \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">22.12±8.69 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">24.08±6.59 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">0.017 \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">Painless toilet seating (days) \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">1 (1-2) \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">2 (1-3) \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">0.001 \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">Patient satisfaction \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">2.88 ± 0.16 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t">1.43 ± 0.44 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="\n \t\t\t\t\ttop\n \t\t\t\t"><0.001 \t\t\t\t\t\t\n \t\t\t\t</td></tr></tbody></table> """ ] ] ] ] "descripcion" => array:1 [ "en" => "Operative and postoperative outcomes." ] ] ] "bibliografia" => array:2 [ "titulo" => "REFERENCES" "seccion" => array:1 [ 0 => array:2 [ "identificador" => "cebibsec10" "bibliografiaReferencia" => array:30 [ 0 => array:3 [ "identificador" => "bib1" "etiqueta" => "1" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Short-term results of Karydakis flap for pilonidal sinus disease" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:5 [ 0 => """ S Petersen \n \t\t\t\t\t\t\t\t """ 1 => """ A Aumann, Kramer \n \t\t\t\t\t\t\t\t """ 2 => """ D Doll \n \t\t\t\t\t\t\t\t """ 3 => """ M Sailer \n \t\t\t\t\t\t\t\t """ 4 => """ G Hellmich \n \t\t\t\t\t\t\t\t """ ] ] ] ] ] "host" => array:2 [ 0 => array:2 [ "doi" => "10.1007/s10151-007-0357-7" "Revista" => array:7 [ "tituloSerie" => "Tech Coloproctol" "fecha" => "2007" "volumen" => "11" "numero" => "3" "paginaInicial" => "235" "paginaFinal" => "240" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/17676268" "web" => "Medline" ] ] ] ] 1 => array:2 [ "doi" => "10.1007/s10151-007-0357-7" "WWW" => array:1 [ "link" => "http://dx.doi.org/10.1007/s10151-007-0357-7" ] ] ] ] ] ] 1 => array:3 [ "identificador" => "bib2" "etiqueta" => "2" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Patient characteristics and symptoms in chronic pilonidal sinus disease" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ 0 => """ K Sondenaa \n \t\t\t\t\t\t\t\t """ 1 => """ E Andersen \n \t\t\t\t\t\t\t\t """ 2 => """ I Nesvik \n \t\t\t\t\t\t\t\t """ 3 => """ JA Søreide \n \t\t\t\t\t\t\t\t """ ] ] ] ] ] "host" => array:2 [ 0 => array:2 [ "doi" => "10.1007/BF00337585" "Revista" => array:7 [ "tituloSerie" => "Int J Colorectal Dis" "fecha" => "1995" "volumen" => "10" "numero" => "1" "paginaInicial" => "39" "paginaFinal" => "42" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/7745322" "web" => "Medline" ] ] ] ] 1 => array:2 [ "doi" => "10.1007/BF00337585" "WWW" => array:1 [ "link" => "http://dx.doi.org/10.1007/BF00337585" ] ] ] ] ] ] 2 => array:3 [ "identificador" => "bib3" "etiqueta" => "3" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Healing by primary closure versus open healing after surgery for pilonidal sinus: systematic review and meta-analysis" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => """ IJ McCallum \n \t\t\t\t\t\t\t\t """ 1 => """ PM King \n \t\t\t\t\t\t\t\t """ 2 => """ J Bruce \n \t\t\t\t\t\t\t\t """ ] ] ] ] ] "host" => array:2 [ 0 => array:2 [ "doi" => "10.1136/bmj.39517.808160.BE" "Revista" => array:7 [ "tituloSerie" => "BMJ" "fecha" => "2008" "volumen" => "336" "numero" => "7649" "paginaInicial" => "868" "paginaFinal" => "871" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/18390914" "web" => "Medline" ] ] ] ] 1 => array:2 [ "doi" => "10.1136/bmj.39517.808160.BE" "WWW" => array:1 [ "link" => "http://dx.doi.org/10.1136/bmj.39517.808160.BE" ] ] ] ] ] ] 3 => array:3 [ "identificador" => "bib4" "etiqueta" => "4" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Natal Cleft Deeper in Patients with Pilonidal Sinus: Implications for Choice of Surgical Procedure" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:6 [ 0 => """ O F Akinci \n \t\t\t\t\t\t\t\t """ 1 => """ M Kurt \n \t\t\t\t\t\t\t\t """ 2 => """ A Terzi \n \t\t\t\t\t\t\t\t """ 3 => """ I Atak \n \t\t\t\t\t\t\t\t """ 4 => """ IE Subasi \n \t\t\t\t\t\t\t\t """ 5 => """ O Akbilgic \n \t\t\t\t\t\t\t\t """ ] ] ] ] ] "host" => array:2 [ 0 => array:2 [ "doi" => "10.1007/DCR.0b013e31819f6189" "Revista" => array:7 [ "tituloSerie" => "Dis Colon Rectum" "fecha" => "2009" "volumen" => "52" "numero" => "5" "paginaInicial" => "1000" "paginaFinal" => "1002" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/19502869" "web" => "Medline" ] ] ] ] 1 => array:2 [ "doi" => "10.1007/DCR.0b013e31819f6189" "WWW" => array:1 [ "link" => "http://dx.doi.org/10.1007/DCR.0b013e31819f6189" ] ] ] ] ] ] 4 => array:3 [ "identificador" => "bib5" "etiqueta" => "5" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Pilonidal cyst of the scalp due to single minor trauma" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ 0 => """ M Kosaka \n \t\t\t\t\t\t\t\t """ 1 => """ M Kida \n \t\t\t\t\t\t\t\t """ 2 => """ M Mori \n \t\t\t\t\t\t\t\t """ 3 => """ H Kamiishi \n \t\t\t\t\t\t\t\t """ ] ] 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CLINICAL SCIENCE

İlhan BaliI, Mehmet AziretII,

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mhmtaziret@gmail.com

Corresponding author:

, Selim SözenI, Seyfi EmirI, Hasan ErdemIII, Süleyman ÇetinkünarIII, Oktay İrkörücüII

I Department of General Surgery, Namık Kemal University, Tekirdağ, Turkey.

II Kars State Hospital General Surgery, Kars, Merkez, Turkey.

III Department of General Surgery, Adana Training and Research Hospital, Adana, Turkey.

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    "textoCompleto" => "<span class="elsevierStyleSections"><span id="cesec10" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="cestitle60">INTRODUCTION</span><p id="para10" class="elsevierStylePara elsevierViewall">Pilonidal sinus &#40;PS&#41; is a common disease of the natal cleft in the sacrococcygeal region with weak hair accumulation occurring in the hair follicles&#44; which can be chronic and undergo acute exacerbation <a class="elsevierStyleCrossRefs" href="#bib1">1&#44;2</a>&#46; The incidence of PS is approximately 26&#47;100&#44;000&#59; it is a benign disease that occurs in young men <a class="elsevierStyleCrossRefs" href="#bib3">3&#44;4</a>&#46;</p><p id="para20" class="elsevierStylePara elsevierViewall">The etiology and pathogenesis of PS are not clear&#44; although the disease is thought to be related to the accumulation of weak and lifeless hair in the intergluteal region&#46; Over time&#44; foreign body reaction occurs&#44; causing abscess and sinus formation&#46; Obesity&#44; trauma&#44; local irritation and a sedentary lifestyle are usually associated with PS <a class="elsevierStyleCrossRefs" href="#bib2">2&#44;5</a>&#46;</p><p id="para30" class="elsevierStylePara elsevierViewall">Although pilonidal sinus can be treated using several defined conservative and surgical methods&#44; recurrence rates remain high <a class="elsevierStyleCrossRef" href="#bib6">6</a>&#46; Complete removal of the pilonidal sinus or sinuses and appropriate reconstruction can lead to successful recovery <a class="elsevierStyleCrossRef" href="#bib7">7</a>&#46; However&#44; collection of the lifeless hair depends on the anatomy of the intergluteal area&#44; and accompanying risk factors can lead to inadequate surgery and subsequent recurrence <a class="elsevierStyleCrossRefs" href="#bib6">6&#44;8</a>&#46;</p><p id="para40" class="elsevierStylePara elsevierViewall">Our aim in this study was to prospectively compare early results in patients with recurrent pilonidal sinus treated with either the Karydakis flap &#40;KF&#41; procedure or Limberg flap rotation &#40;LF&#41;&#46;</p></span><span id="cesec20" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="cestitle70">MATERIALS AND METODS</span><p id="para50" class="elsevierStylePara elsevierViewall">This study was conducted at the surgery departments at Elaz&#305;&#287;&#44; Kayseri and Adana Numune Training and Research Hospitals from January 2009 to December 2013&#46; Seventy-one patients who were treated only for recurrent pilonidal disease were eligible for the study&#46; Patients with previous surgical procedures&#44; including primary closure &#40;71 cases&#41; were considered to have recurrent disease&#46; The 71 patients who had been treated with midline closure were divided into the following two treatment groups&#58; the LF group &#40;Limberg flap&#41; and KF group &#40;Karydakis flap&#41;&#46; All patients were prospectively evaluated in terms of gender and age&#44; location of sinus pits&#44; postoperative length of hospital stay&#44; postoperative complications &#40;wound dehiscence&#44; infection&#44; hematoma&#44; seroma and cosmetics&#41; and recurrence&#46; The Ethical Committee of our center approved the study protocol&#46;</p><span id="cesec30" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="cestitle80">Surgical procedure</span><span id="cesec40" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="cestitle90">Limberg flap method</span><p id="para60" class="elsevierStylePara elsevierViewall">All patients were operated on under spinal anesthesia in the operating room&#46; After anesthesia&#44; the patients were placed in the prone&#44; jack-knife position&#44; with the buttocks strapped apart using wide adhesive tape&#46; Methylene blue was injected in the sinus tract using a 6-Fr feeding tube&#46; The excision was carried down to the fascia overlying the sacrum and laterally to the fascia of the gluteus maximus muscle&#46; Dissection was performed with electrocautery&#46; A Limberg flap was prepared from the right or left gluteal region&#46; A suction drain &#40;B-VAK Wound Drainage System&#8482;&#44; 10 Ch&#44; Ref&#46; 17110211&#44; BiCakCilar&#44; Istanbul&#44; Turkey&#41; was placed through a separate incision that was located 2 cm lateral from the initial incision and maintained in place until the drainage decreased to less than 10 ml&#47;day &#40;<a class="elsevierStyleCrossRefs" href="#fig1">Figures 1 and 2</a>&#41;&#46;</p><elsevierMultimedia ident="fig1"></elsevierMultimedia><elsevierMultimedia ident="fig2"></elsevierMultimedia></span><span id="cesec50" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="cestitle100">Karydakis flap procedure</span><p id="para70" class="elsevierStylePara elsevierViewall">Operations were performed under spinal anesthesia with the patient in the prone position with the buttocks strapped apart&#46; No patient was given prophylactic antibiotics&#46; The surgical site was shaved immediately before the operation&#44; and the skin was prepared with povidone-iodine solution&#46; Methylene blue was infused through the sinus to delineate the fistula tract in patients with open orifices&#46; A Karydakis flap was created as described previously <a class="elsevierStyleCrossRefs" href="#bib2">2&#44;4</a> &#40;<a class="elsevierStyleCrossRefs" href="#fig1">Figures 1 and 3</a>&#41;&#46; A suction drain &#40;B-VAK Wound Drainage System&#8482;&#44; 10 Ch&#44; Ref&#46; 17110211&#44; B&#305;&#231;ak&#231;&#305;lar&#44; Istanbul&#44; Turkey&#41; was placed through a separate incision that was located 2 cm lateral from the initial incision in 17 &#40;50 percent&#41; patients &#40;Group 1&#41; and was maintained in place until the drainage decreased to less than 10 ml&#47;day&#46; The remaining 17 patients underwent surgery without any drain placement &#40;Group 2&#41;&#46; All incisions were dressed under pressure using several gauze packs and tight bandages &#40;<a class="elsevierStyleCrossRefs" href="#fig1">Figures 1 and 3</a>&#41;&#46;</p><elsevierMultimedia ident="fig3"></elsevierMultimedia></span></span><span id="cesec60" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="cestitle110">Inclusion criteria</span><p id="para80" class="elsevierStylePara elsevierViewall">Patients willing to give written informed consent&#46;</p><p id="para90" class="elsevierStylePara elsevierViewall">Presence of recurrent pilonidal sinus&#46;</p><p id="para100" class="elsevierStylePara elsevierViewall">Adult &#40;over 16 years of age&#41; undergoing surgery for recurrent pilonidal sinus&#46;</p><p id="para110" class="elsevierStylePara elsevierViewall">International normalizing ratio &#40;INR&#41; of less than 1&#46;5&#46;</p><p id="para120" class="elsevierStylePara elsevierViewall">Prothrombin time &#40;PT&#41; of less than 15 s&#46;</p><p id="para130" class="elsevierStylePara elsevierViewall">Partial thromboplastin &#40;PTT&#41; time near normal&#46;</p><p id="para140" class="elsevierStylePara elsevierViewall">Platelet count greater than 50&#44;000 per mm<span class="elsevierStyleSup">3</span> to limit the risk of bleeding&#46;</p><p id="para150" class="elsevierStylePara elsevierViewall">No infection at time of surgery&#46;</p></span><span id="cesec70" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="cestitle120">Exclusion criteria</span><p id="para160" class="elsevierStylePara elsevierViewall">Patients not willing to give informed consent&#46;</p><p id="para170" class="elsevierStylePara elsevierViewall">Age less than 16 years&#46;</p><p id="para180" class="elsevierStylePara elsevierViewall">Patient presenting with different conditions mimicking pilonidal sinus&#46;</p><p id="para190" class="elsevierStylePara elsevierViewall">Chronic medical conditions&#44; such as diabetes mellitus&#44; renal failure&#44; or immunosuppression&#46;</p></span><span id="cesec80" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="cestitle130">Randomization criteria</span><p id="para200" class="elsevierStylePara elsevierViewall">In this study&#44; patients with recurrent pilonidal sinus were accepted who were between 16-40 years of age and were without pilonidal sinus abscess or infection&#46;</p></span><span id="cesec90" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="cestitle140">Statistical analysis</span><p id="para210" class="elsevierStylePara elsevierViewall">Statistical analyses were performed using SPSS &#40;Statistical Package for the Social Sciences ver&#46; 10&#46;0&#44; SPSS Inc&#44; Chicago&#44; Illinois&#44; USA&#41; computer software&#46; Student&#39;s <span class="elsevierStyleItalic">t</span> test was used to compare age between the groups&#46; Complications were analyzed using the &#967;2 test&#46; Parametric variables that did not exhibit normal distribution between groups were compared using the Mann-Whitney U test&#46; Chi-square and Fisher&#39;s exact tests were used to compare categorical variables&#46; For all statistical analyses&#44; <span class="elsevierStyleItalic">p</span>&#60;0&#46;05 was considered significant&#46;</p></span></span><span id="cesec100" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="cestitle150">RESULTS</span><p id="para220" class="elsevierStylePara elsevierViewall">In this study&#44; 71 patients with recurrent pilonidal disease were enrolled&#44; of whom 37 were treated using the standard Limberg flap procedure and 34 were treated using the Karydakis flap procedure &#40;<a class="elsevierStyleCrossRef" href="#tbl1">Table 1</a>&#41;&#46; The two groups did not differ in age or body mass index&#46; Similarly&#44; the two groups did not differ significantly in terms of sinus pit location or the presence of single or multiple pits &#40;<span class="elsevierStyleItalic">p</span>&#62;0&#46;05&#41;&#46; The operative time was longer in the LF group&#46; Hospitalization time was also significantly higher in the LF group than in the KF group&#46; Most patients in the LF group were mobilized on the first postoperative day&#44; and the median time to first mobilization was earlier in the LF group than in KF group &#91;1 &#40;1-1&#41; <span class="elsevierStyleItalic">vs&#46;</span> 2 &#40;1-3&#41; days&#44; respectively&#59; <span class="elsevierStyleItalic">p&#60;</span>0&#46;001&#93;&#46; The median duration of incapacity for work was 17 &#40;14-20&#41; days in KF group and 8 &#40;6-12&#41; days in the LF group &#40;<span class="elsevierStyleItalic">p&#60;</span>0&#46;001&#41; &#40;<a class="elsevierStyleCrossRef" href="#tbl2">Table 2</a>&#41;&#46; In KF group&#44; eight patients had infection and four had seroma&#46; Total wound dehiscence and flap necrosis did not occur in any patient&#46; Seven patients had seroma with negative culture in all studied patients&#46; Flap edema occurred in four patients in the LF group&#46; Wound infection occurred in four patients in the LF group &#40;<a class="elsevierStyleCrossRef" href="#tbl1">Table 1</a>&#41;&#46; The mean time for complete healing of the wound after rhomboid excision and Limberg flap was 22&#46;12&#177;8&#46;69 days&#46; The median VAS pain score was significantly lower in the LF group &#40;<span class="elsevierStyleItalic">p&#60;</span>0&#46;001&#41;&#46; No recurrence occurred in any of the patients during the follow-up period&#46; When patient satisfaction was compared&#44; the LF group received 2&#46;88&#177;0&#46;16 points and KF group received 1&#46;43&#177;0&#46;44&#59; the patients in the LF group were more satisfied in terms of aesthetics &#40;<span class="elsevierStyleItalic">p</span>&#60;0&#46;001&#41;&#46;</p><elsevierMultimedia ident="tbl1"></elsevierMultimedia><elsevierMultimedia ident="tbl2"></elsevierMultimedia></span><span id="cesec110" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="cestitle160">DISCUSSION</span><p id="para230" class="elsevierStylePara elsevierViewall">Pilonidal sinus was first described by Anderson in 1847 and is often seen in the intergluteal region&#46; This chronic disease is characterized by acute exacerbations <a class="elsevierStyleCrossRefs" href="#bib1">1-3&#44;9</a>&#46; PS usually occurs in healthy young men &#40;Male&#47;Female &#61; 4-5&#47;1&#41;&#44; has a negative cosmetic appearance&#44; and can cause loss of worktime <a class="elsevierStyleCrossRefs" href="#bib2">2-4</a>&#46; Gurer et al&#46; <a class="elsevierStyleCrossRef" href="#bib14">14</a> reported a mean patient age of 25&#46;5 and a gender balance of 95&#37; males in a series detailing the Karydakis flap procedure&#46; In our series&#44; the mean age was 24&#44; and more than 95&#37; of the patients were male&#46;</p><p id="para240" class="elsevierStylePara elsevierViewall">The etiology and pathogenesis of PS is frequently associated with both congenital and acquired factors&#46; It has been suggested that PS starts as a chronic process involving the accumulation of lifeless hairs and subcutaneous hair deposition in the intergluteal region that leads to inflammation and infection <a class="elsevierStyleCrossRefs" href="#bib3">3-5</a>&#46;</p><p id="para250" class="elsevierStylePara elsevierViewall">Several treatment procedures have been described in the literature&#44; ranging from simple incision and drainage to the use of complex plastic flaps for cleft obliteration&#46; The ideal technique for the treatment of sacrococcygeal PS disease is controversial <a class="elsevierStyleCrossRefs" href="#bib2">2&#44;5</a>&#46; Medical treatment methods include alcohol&#44; phenol and silver nitrate injection into the cavity&#46; Surgical treatment methods include curettage after fistulotomy&#44; leaving an open or marsupialized wound after cystectomy&#44; Bascom surgery&#44; primary excision and closure&#44; the Karydakis flap procedure &#40;KF&#41;&#44; or sinus excision and skin graft and flap methods&#44; such as Limberg flap rotation &#40;LF&#41;&#46; Surgical treatment is often preferred <a class="elsevierStyleCrossRefs" href="#bib8">8&#44;11</a>&#46;</p><p id="para260" class="elsevierStylePara elsevierViewall">Ideally&#44; the goals of treatment for this disease should be reliable wound healing with a low risk of recurrence&#44; a short period of hospitalization&#44; minimal inconvenience to the patient&#44; and low morbidity with few wound-management problems <a class="elsevierStyleCrossRefs" href="#bib6">6&#44;8&#44;21</a>&#46;</p><p id="para270" class="elsevierStylePara elsevierViewall">Recurrence is the main problem in the treatment of pilonidal sinus&#46; In 1970&#44; Foss <a class="elsevierStyleCrossRef" href="#bib26">26</a> reported a collective series of 1&#44;129 pilonidal sinus patients treated with excision and primary closure by different investigators&#46; The failure rate of primary healing was 16&#37;&#44; the length of hospitalization averaged 21&#46;7 days&#44; and the recurrence rate was 16&#37;&#46; Several flap techniques have been described with recurrence rates ranging between zero and 6-8&#37; <a class="elsevierStyleCrossRefs" href="#bib6">6-8&#44;10-13</a>&#46;</p><p id="para280" class="elsevierStylePara elsevierViewall">The Karydakis flap procedure was first described by George Karydakis <a class="elsevierStyleCrossRef" href="#bib8">8</a> in 1973 and has frequently been used to treat sacrococcygeal PS&#46; The KF achieves symmetric closure of the pilonidal wounds by avoiding placement of the wound in the midline at the depth of the natal cleft and also flattens the cleft&#44; thereby reducing hair accumulation and mechanical irritation and decreasing recurrence <a class="elsevierStyleCrossRefs" href="#bib8">8&#44;9&#44;30</a>&#46;</p><p id="para290" class="elsevierStylePara elsevierViewall">Karydakis <a class="elsevierStyleCrossRef" href="#bib8">8</a> reported a recurrence rate of 1&#37;&#44; a complication rate of 8&#37;&#44; and a length of hospital stay of 3 days&#46; Can et al&#46; <a class="elsevierStyleCrossRef" href="#bib15">15</a> reported a recurrence rate of 4&#46;6&#37; and a complication rate of 8&#46;9&#37;&#44; and Sakr et al&#46; <a class="elsevierStyleCrossRef" href="#bib16">16</a> determined recurrence rates of 2&#46;4&#37; and a complication rate of 10&#37; in their KF series&#46; In a similar study&#44; S&#246;zen et al&#46; <a class="elsevierStyleCrossRef" href="#bib17">17</a> reported a recurrence rate of 1&#46;5&#37; and a complication rate of 6&#37;&#46; In our series&#44; no recurrence was observed in either group&#46; In the KF group&#44; the complication rate was 10&#37;&#44; and the mean duration of hospital stay was 3 days&#46;</p><p id="para300" class="elsevierStylePara elsevierViewall">Wound infection&#44; fluid collection&#44; edema&#44; hematoma and wound separation can occur after use of the Karydakis flap procedure and other surgical techniques&#46; The use of drains after surgery can be used to prevent fluid accumulation&#44; edema and hematoma formation in such cases <a class="elsevierStyleCrossRefs" href="#bib14">14&#44;17</a>&#46; Gurer et al&#46; <a class="elsevierStyleCrossRef" href="#bib14">14</a> reported that fluid accumulation is reduced after the routine use of post-operative drains&#46; Bessa <a class="elsevierStyleCrossRef" href="#bib18">18</a> determined that the percentage of cases with fluid retention after drain placement was 2&#46;4&#37;&#46; In our KF group&#44; 5&#46;6&#37; of patients experienced fluid collection&#44; 11&#37; experienced wound infection&#44; and 1&#46;4&#37; experienced hematoma&#46; In contrast&#44; in the LF group&#44; 4&#46;2&#37; of patients experienced fluid collection&#44; 5&#46;6&#37; experienced wound infection&#44; and 11&#37; experienced hematoma&#46;</p><p id="para310" class="elsevierStylePara elsevierViewall">The LF and KF procedures not only cover the wound but also&#44; in theory&#44; flatten the natal cleft and decrease hair accumulation&#44; mechanical irritation and the risk of recurrence <a class="elsevierStyleCrossRefs" href="#bib2">2&#44;11</a>&#46;</p><p id="para320" class="elsevierStylePara elsevierViewall">Limberg flap rotation is clearly preferred for safety reasons given its low recurrence and complication rates <a class="elsevierStyleCrossRef" href="#bib19">19</a>&#46; In patients with recurrence and multiple sinuses&#44; lateral flap rotations are implemented by removing the midline <a class="elsevierStyleCrossRefs" href="#bib6">6&#44;19</a>&#46;</p><p id="para330" class="elsevierStylePara elsevierViewall">Mentes et al&#46; <a class="elsevierStyleCrossRef" href="#bib20">20</a>&#44; Ersoy et al&#46; <a class="elsevierStyleCrossRef" href="#bib21">21</a>&#44; and Campbell et al&#46; <a class="elsevierStyleCrossRef" href="#bib22">22</a> reported that modified Limberg flaps presented lower recurrence and complication rates than KF in their respective series&#46; The reported recurrence rate for Limberg flap varies from 0&#46;8 to 2&#46;7&#37; <a class="elsevierStyleCrossRef" href="#bib21">21</a>&#46; Topgul et al&#46; <a class="elsevierStyleCrossRef" href="#bib27">27</a> operated on 200 patients&#44; and the recurrence rate was found to be 2&#46;5&#37;&#46; Daphan et al&#46; <a class="elsevierStyleCrossRef" href="#bib28">28</a> operated on 147 patients with a median follow-up time of 13&#46;1 months&#44; and recurrence was noted in 4&#46;8&#37; of patients&#46;</p><p id="para340" class="elsevierStylePara elsevierViewall">Ertan et al&#46; <a class="elsevierStyleCrossRef" href="#bib23">23</a> reported that a Limberg flap recurrence rate of 2&#37; compared to 12&#37; in a primary closure group&#46; Conversely&#44; Ate&#351; et al&#46; <a class="elsevierStyleCrossRef" href="#bib24">24</a> reported lower recurrence and complication rates for the KF technique than for the LF technique&#46; The mean duration of hospital discharge after Limberg flap procedure reported by Urhan et al&#46; <a class="elsevierStyleCrossRef" href="#bib6">6</a> was 3&#46;7 days&#44; and Kapan et al&#46; <a class="elsevierStyleCrossRef" href="#bib19">19</a> reported a duration of 5&#46;3 days&#46;</p><p id="para350" class="elsevierStylePara elsevierViewall">In our study&#44; recurrence was not observed in either group&#59; in addition&#44; time to discharge from hospital and complication rates were similar to values reported in the literature&#46; The Limberg flap group had lower mean time to hospital discharge &#40;LF&#47;KF&#61;3&#47;1&#44; 4 days&#41; &#40;<span class="elsevierStyleItalic">p</span>&#61;0&#46;001&#41; and lower wound infection rates &#40;<span class="elsevierStyleItalic">p</span>&#61;0&#46;001&#41; than the KF group&#46; In addition&#44; comparison of the two groups showed a difference in terms of flap edema and hematoma &#40;<span class="elsevierStyleItalic">p</span>&#61;0&#46;017 and <span class="elsevierStyleItalic">p</span>&#61;0&#46;004&#44; respectively&#41;&#46;</p><p id="para360" class="elsevierStylePara elsevierViewall">A Cochrane overview has been performed to provide evidence-based guidance for surgical treatment <a class="elsevierStyleCrossRef" href="#bib3">3</a>&#46; The review concluded that off-midline closure &#40;including rhomboid&#44; Karydakis and Bascom flaps&#41; is the best choice if the sinus is to be excised and sutured&#44; and this closure is associated with shorter hospital stay and the lowest recurrence rates <a class="elsevierStyleCrossRef" href="#bib29">29</a>&#46;</p><p id="para370" class="elsevierStylePara elsevierViewall">Other important points in the treatment of pilonidal sinus surgery are return to daily activities and work&#44; postoperative pain score &#40;VAS&#41;&#44; duration of operation&#44; time sitting on the toilet&#44; and patient aesthetic satisfaction&#46; In patients with recurrence and large defects&#44; undergoing flap procedures can reduce aesthetic satisfaction&#46; Akinci et al&#46; <a class="elsevierStyleCrossRef" href="#bib4">4</a> reported that return to daily activities after the Karydakis flap procedure was 12&#46;4 to 20 days and that postoperative patient satisfaction was high&#46;</p><p id="para380" class="elsevierStylePara elsevierViewall">Can et al&#46; <a class="elsevierStyleCrossRef" href="#bib15">15</a> reported 70&#37; patient satisfaction after the Karydakis flap procedure&#44; and a recent study reported satisfaction as high as 91&#37;&#46; Can et al&#46; <a class="elsevierStyleCrossRef" href="#bib15">15</a> and Ersoy et al&#46; <a class="elsevierStyleCrossRef" href="#bib21">21</a> determined that patients undergoing the Karydakis flap procedure and LF experience similar durations of hospital stay and return to work times&#46; Karaca et al&#46;<a class="elsevierStyleCrossRef" href="#bib25">25</a> reported that the Limberg Flap group provided better postoperative pain score &#40;visual analogue scale&#58; VAS&#41;&#44; complication rate&#44; time to discontinuation of analgesics&#44; and painless sitting than the KF group&#44; and Ersoy et al&#46; <a class="elsevierStyleCrossRef" href="#bib21">21</a> found similar results&#46; Can et al&#46; <a class="elsevierStyleCrossRef" href="#bib15">15</a> showed that mean operation time for the Karydakis flap procedure was 49&#177;7 minutes&#44; compared with 52&#177;5 minutes for the Limberg flap procedure&#46; In our study&#44; the LF group exhibited a lower VAS score &#40;2&#47;4&#41;&#44; higher patient satisfaction &#40;2&#46;8&#47;1&#46;43&#41;&#44; earlier first mobilization &#40;1&#47;2 days&#41; and more painless toilet sitting&#46; &#40;1&#47;2 day&#41;&#46; These patients also had shorter complete healing time &#40;22&#47;24 day&#41; than the KF group &#40;<span class="elsevierStyleItalic">p</span>&#8804;0&#46;001&#41;&#46; On the other hand&#44; the KF group had a shorter operation time than the LF group &#40;48 and 54 minutes&#44; respectively&#41; &#40;<span class="elsevierStyleItalic">p</span>&#61;0&#46;001&#41;&#46;</p><p id="para390" class="elsevierStylePara elsevierViewall">The Limberg flap procedure is a safe choice for the surgical treatment of sacrococcygeal recurrent pilonidal sinus disease due to its low complication rate&#44; short length of hospital stay&#44; early return work&#44; low VAS score&#44; high patient satisfaction and shorter complete healing duration&#46; Therefore&#44; we recommend the Limberg flap procedure for the treatment of recurrent pilonidal sinus disease<span class="elsevierStyleBold">&#46;</span></p></span><span id="cesec120" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="cestitle170">AUTHOR CONTRIBUTIONS</span><p id="para400" class="elsevierStylePara elsevierViewall">Bali &#304; participated in the project design and execution&#44; experimental practical work&#44; data collection&#44; transcription and coordination&#46; Aziret M participated in the project design and execution&#44; experimental practical work and data collection&#46; S&#246;zen S and &#199;etink&#252;nar S participated in the project design&#44; execution and experimental work&#46; Emir S and Erdem H collected the data and performed the statistical analysis&#46; &#304;rk&#246;r&#252;c&#252; O participated in the project design and data collection&#46;</p></span></span>"
    "textoCompletoSecciones" => array:1 [
      "secciones" => array:7 [
        0 => array:2 [
          "identificador" => "xpalclavsec1582300"
          "titulo" => "KEYWORDS"
        ]
        1 => array:2 [
          "identificador" => "cesec10"
          "titulo" => "INTRODUCTION"
        ]
        2 => array:3 [
          "identificador" => "cesec20"
          "titulo" => "MATERIALS AND METODS"
          "secciones" => array:5 [
            0 => array:3 [
              "identificador" => "cesec30"
              "titulo" => "Surgical procedure"
              "secciones" => array:2 [
                0 => array:2 [
                  "identificador" => "cesec40"
                  "titulo" => "Limberg flap method"
                ]
                1 => array:2 [
                  "identificador" => "cesec50"
                  "titulo" => "Karydakis flap procedure"
                ]
              ]
            ]
            1 => array:2 [
              "identificador" => "cesec60"
              "titulo" => "Inclusion criteria"
            ]
            2 => array:2 [
              "identificador" => "cesec70"
              "titulo" => "Exclusion criteria"
            ]
            3 => array:2 [
              "identificador" => "cesec80"
              "titulo" => "Randomization criteria"
            ]
            4 => array:2 [
              "identificador" => "cesec90"
              "titulo" => "Statistical analysis"
            ]
          ]
        ]
        3 => array:2 [
          "identificador" => "cesec100"
          "titulo" => "RESULTS"
        ]
        4 => array:2 [
          "identificador" => "cesec110"
          "titulo" => "DISCUSSION"
        ]
        5 => array:2 [
          "identificador" => "cesec120"
          "titulo" => "AUTHOR CONTRIBUTIONS"
        ]
        6 => array:1 [
          "titulo" => "REFERENCES"
        ]
      ]
    ]
    "pdfFichero" => "main.pdf"
    "tienePdf" => true
    "fechaRecibido" => "2014-11-10"
    "fechaAceptado" => "2015-02-13"
    "PalabrasClave" => array:1 [
      "en" => array:1 [
        0 => array:4 [
          "clase" => "keyword"
          "titulo" => "KEYWORDS"
          "identificador" => "xpalclavsec1582300"
          "palabras" => array:3 [
            0 => "Karydakis flap"
            1 => "Limberg technique"
            2 => "Recurrent pilonidal sinus"
          ]
        ]
      ]
    ]
    "tieneResumen" => true
    "resumen" => array:1 [
      "en" => array:2 [
        "resumen" => "<span id="ceabs10" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="cestitle10">OBJECTIVE&#58;</span><p id="spara60" class="elsevierStyleSimplePara elsevierViewall">Sacrococcygeal pilonidal sinus is common in young men and may recur over time after surgery&#46; We investigated whether a factor exists that can aid in the determination of the preferred technique between the early Limberg flap and Karydakis flap techniques for treating recurrent pilonidal sinus&#46;</p></span> <span id="ceabs20" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="cestitle20">MATERIALS AND METHODS&#58;</span><p id="spara70" class="elsevierStyleSimplePara elsevierViewall">This prospective and randomized study enrolled 71 patients with recurrent pilonidal sinus in whom the Limberg flap or Karydakis flap techniques were applied for reconstruction after excision&#46; Patients were divided into two groups as follows&#58; 37 patients were treated with the Limberg flap technique and 34 patients were treated with the Karydakis flap technique&#46; Fluid collection&#44; wound infection&#44; flap edema&#44; hematoma&#44; partial wound separation&#44; return to daily activities&#44; pain score&#44; complete healing time&#44; painless seating and patient satisfaction were compared between the groups&#46; <span class="elsevierStyleBold">ClinicalTrial&#46;gov&#58;</span> NCT02287935&#46;</p></span> <span id="ceabs30" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="cestitle30">RESULTS&#58;</span><p id="spara80" class="elsevierStyleSimplePara elsevierViewall">The development rates of total fluid collection&#44; wound infection&#44; flap edema&#44; hematoma&#44; and partial wound separation were 9&#46;8&#37;&#44; 16&#37;&#44; 7&#37;&#44; 15&#37; and 4&#46;2&#37;&#44; respectively&#59; total flap necrosis was not observed in any patient &#40;<span class="elsevierStyleItalic">p</span>&#60;0&#46;001&#41;&#46; During the average follow-up of 28 months&#44; no patients &#40;0&#37;&#41; developed recurrent disease&#46; The two groups differed with respect to early surgical complications &#40;<span class="elsevierStyleItalic">p</span>&#60;0&#46;001&#41;&#46;</p></span> <span id="ceabs40" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="cestitle40">CONCLUSION&#58;</span><p id="spara90" class="elsevierStyleSimplePara elsevierViewall">In this study&#44; use of the Limberg flap was associated with lower complication rates&#44; shorter length of hospital stay&#44; early return to work&#44; low pain score&#44; high patient satisfaction and better complete healing duration&#46; Therefore&#44; we recommend the Limberg flap for treatment of recurrent pilonidal sinus&#46;</p></span>"
        "secciones" => array:4 [
          0 => array:2 [
            "identificador" => "ceabs10"
            "titulo" => "OBJECTIVE&#58;"
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          1 => array:2 [
            "identificador" => "ceabs20"
            "titulo" => "MATERIALS AND METHODS&#58;"
          ]
          2 => array:2 [
            "identificador" => "ceabs30"
            "titulo" => "RESULTS&#58;"
          ]
          3 => array:2 [
            "identificador" => "ceabs40"
            "titulo" => "CONCLUSION&#58;"
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    "NotaPie" => array:1 [
      0 => array:1 [
        "nota" => "<p class="elsevierStyleNotepara" id="cenpara10">No potential conflict of interest was reported&#46;</p>"
      ]
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      0 => array:7 [
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        "etiqueta" => "Figure 1"
        "tipo" => "MULTIMEDIAFIGURA"
        "mostrarFloat" => true
        "mostrarDisplay" => false
        "figura" => array:1 [
          0 => array:4 [
            "imagen" => "gr1.jpeg"
            "Alto" => 451
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            "Tamanyo" => 30069
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        "descripcion" => array:1 [
          "en" => "<p id="spara10" class="elsevierStyleSimplePara elsevierViewall">Asymmetric elliptical excision <span class="elsevierStyleBold">&#40;1A&#41;</span>&#46; Closure of the cavity with Karydakis flap <span class="elsevierStyleBold">&#40;1B&#41;</span>&#46; Rhomboid excision <span class="elsevierStyleBold">&#40;2A&#41;</span>&#46; Limberg flap and construction after rhomboid excision <span class="elsevierStyleBold">&#40;2B&#41;</span>&#46;</p>"
        ]
      ]
      1 => array:7 [
        "identificador" => "fig2"
        "etiqueta" => "Figure 2"
        "tipo" => "MULTIMEDIAFIGURA"
        "mostrarFloat" => true
        "mostrarDisplay" => false
        "figura" => array:1 [
          0 => array:4 [
            "imagen" => "gr2.jpeg"
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            "Tamanyo" => 29580
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        "descripcion" => array:1 [
          "en" => "<p id="spara20" class="elsevierStyleSimplePara elsevierViewall">Limberg flap technique&#46;</p>"
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      ]
      2 => array:7 [
        "identificador" => "fig3"
        "etiqueta" => "Figure 3"
        "tipo" => "MULTIMEDIAFIGURA"
        "mostrarFloat" => true
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        "figura" => array:1 [
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            "imagen" => "gr3.jpeg"
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        "descripcion" => array:1 [
          "en" => "<p id="spara30" class="elsevierStyleSimplePara elsevierViewall">Karydakis flap rotation&#46;</p>"
        ]
      ]
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        "identificador" => "tbl1"
        "etiqueta" => "Table 1"
        "tipo" => "MULTIMEDIATABLA"
        "mostrarFloat" => true
        "mostrarDisplay" => false
        "tabla" => array:1 [
          "tablatextoimagen" => array:1 [
            0 => array:1 [
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                0 => """
                  <table border="0" frame="\n
                  \t\t\t\t\tvoid\n
                  \t\t\t\t" class=""><thead title="thead"><tr title="table-row"><th class="td" title="\n
                  \t\t\t\t\ttable-head\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t" scope="col">Variable&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t\t\t</th><th class="td" title="\n
                  \t\t\t\t\ttable-head\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t" scope="col">Limberg Flap&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t\t\t</th><th class="td" title="\n
                  \t\t\t\t\ttable-head\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t" scope="col">Karydakis Flap&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t\t\t</th><th class="td" title="\n
                  \t\t\t\t\ttable-head\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t" scope="col"><span class="elsevierStyleItalic">p</span>-value&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t\t\t</th></tr></thead><tbody title="tbody"><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Gender &#40;M&#47;F&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">32&#47;5&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">32&#47;2&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">0&#46;650&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Age &#40;years&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">25&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">23&#46;5&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">0&#46;21&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Location&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Midline single&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">18&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">22&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">0&#46;55&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Midline multiple&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">14&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">10&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Hirsute Nature&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">24&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">22&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">0&#46;831&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">History of Smoking&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">14&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">12&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">0&#46;54&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Duration of preoperative complaints &#40;months&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">14&#46;32&#177;10&#46;12&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">12&#46;66&#177;4&#46;43&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">0&#46;08&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Length of hospital stay &#40;days&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">1&#46;44 &#40;1-3&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">3 &#40;3-6&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">0&#46;001&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Obesity&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Overweight &#40;BMI 25-29&#46;9&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">22&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">18&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">0&#46;455&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Obese &#40;BMI 30-39&#46;9&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">13&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">14&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Morbidly obese &#40;BMI &#8805; 40&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">3&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">2&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Follow up &#40;months&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">28&#46;2&#177;7&#46;65&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">27&#46;6&#177;8&#46;32&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">0&#46;750&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Fluid collection&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">3&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">4&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">0&#46;82&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Wound infection&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">4&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">8&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">0&#46;001&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Flap edema&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">4&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">1&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">0&#46;017&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Hematoma&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">8&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">3&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">0&#46;004&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Partial wound dehiscence&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">1&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">2&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">0&#46;590&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Recurrence&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr></tbody></table>
                  """
              ]
            ]
          ]
        ]
        "descripcion" => array:1 [
          "en" => "<p id="spara40" class="elsevierStyleSimplePara elsevierViewall">Clinical comparison&#44; operative characteristics and complications between groups&#46;</p>"
        ]
      ]
      4 => array:7 [
        "identificador" => "tbl2"
        "etiqueta" => "Table 2"
        "tipo" => "MULTIMEDIATABLA"
        "mostrarFloat" => true
        "mostrarDisplay" => false
        "tabla" => array:1 [
          "tablatextoimagen" => array:1 [
            0 => array:1 [
              "tabla" => array:1 [
                0 => """
                  <table border="0" frame="\n
                  \t\t\t\t\tvoid\n
                  \t\t\t\t" class=""><thead title="thead"><tr title="table-row"><th class="td" title="\n
                  \t\t\t\t\ttable-head\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t" scope="col">Variable&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t\t\t</th><th class="td" title="\n
                  \t\t\t\t\ttable-head\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t" scope="col">Limberg Flap group&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t\t\t</th><th class="td" title="\n
                  \t\t\t\t\ttable-head\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t" scope="col">Karydakis Flap group&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t\t\t</th><th class="td" title="\n
                  \t\t\t\t\ttable-head\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t" scope="col"><span class="elsevierStyleItalic">p</span>-value&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t\t\t</th></tr></thead><tbody title="tbody"><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Duration of operation &#40;min&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">54 &#40;50-70&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">48 &#40;40-60&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">0&#46;001&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Time to first mobilization &#40;days&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">1 &#40;1-1&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">2 &#40;1-3&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&#60;0&#46;001&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Duration of incapacity for work&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">8 &#40;6-12&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">17 &#40;14-20&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&#60;0&#46;001&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Pain VAS score&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">2 &#40;1-3&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">4 &#40;2-6&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&#60;0&#46;001&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Complete healing time &#40;days&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">22&#46;12&#177;8&#46;69&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">24&#46;08&#177;6&#46;59&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">0&#46;017&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Painless toilet seating &#40;days&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">1 &#40;1-2&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">2 &#40;1-3&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">0&#46;001&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Patient satisfaction&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">2&#46;88 &#177; 0&#46;16&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
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Article information

ISSN: 18075932
Original language: English

DOI:10.6061/clinics/2015(05)08

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Year/Month	Html	Pdf	Total

2024 November	22	1	23
2024 October	229	27	256
2024 September	288	37	325
2024 August	367	36	403
2024 July	311	21	332
2024 June	134	21	155
2024 May	120	26	146
2024 April	103	18	121
2024 March	151	22	173
2024 February	168	17	185
2024 January	173	18	191
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2023 June	79	4	83
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