LETTER TO THE EDITOR
Further peer review failures
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Image shows a continuous surface and erosion of the regenerated hyaline cartilage (insert) in the central zone of the original defect area (area within the orange line). A cystic space (arrow) that was filled with granulation tissue in the subchondral area (blue line) with sclerosing change is shown (H & E stain).- Group B specimen. Image shows a continuous surface and erosion of the regenerated hyaline cartilage (insert) in the central zone of the original defect area (area within the orange line). A cystic space (arrow) that was filled with granulation tissue in the subchondral area (blue line) with sclerosing change is shown (H & E stain).</p>" ] ] ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "Tzong-Fu Kuo, Ming-Fang Lin, Yun-Ho Lin, Ying-Chun Lin, Rou-Jen Su, Hui-Wen Lin, Wing P. 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"apellidos" => "Chan" ] ] ] ] ] "idiomaDefecto" => "en" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1807593222023456?idApp=UINPBA00004N" "url" => "/18075932/0000006600000010/v1_202212011334/S1807593222023456/v1_202212011334/en/main.assets" ] "itemAnterior" => array:19 [ "pii" => "S1807593222023432" "issn" => "18075932" "doi" => "10.1590/S1807-59322011001000024" "estado" => "S300" "fechaPublicacion" => "2011-10-01" "aid" => "2343" "copyright" => "CLINICS" "documento" => "article" "crossmark" => 0 "licencia" => "https://creativecommons.org/licenses/by-nc/3.0/" "subdocumento" => "rev" "cita" => "Clinics. 2011;66:1825-31" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:1 [ "total" => 0 ] "en" => array:12 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">REVIEW</span>" "titulo" => "Sepsis-associated encephalopathy: not just delirium" "tienePdf" => "en" "tieneTextoCompleto" => "en" "tieneResumen" => "en" "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "1825" "paginaFinal" => "1831" ] ] "contieneResumen" => array:1 [ "en" => true ] "contieneTextoCompleto" => array:1 [ "en" => true ] "contienePdf" => array:1 [ "en" => true ] "resumenGrafico" => array:2 [ "original" => 0 "multimedia" => array:7 [ "identificador" => "fig1" "etiqueta" => "Figure 1" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr1.jpeg" "Alto" => 359 "Ancho" => 478 "Tamanyo" => 33148 ] ] "descripcion" => array:1 [ "en" => "<p id="spara10" class="elsevierStyleSimplePara elsevierViewall">Schematic representation of the main pathophysiological mechanisms of SAE. The inflammatory response is represented by TNF-α induction, which increases BBB damage and the liberation of aquaporin 4 to cause brain edema. Mitochondrial dysfunction and the reduction in oxidative phosphorylation efficiency (cytochrome c malfunction) may induce apoptosis and trigger brain injury. The accumulation of false neurotransmitters may increase intracellular calcium content and contribute to encephalopathy. Cerebral perfusion may be altered, rendering brain function more susceptible to injury. TNF-α: Tumor necrosis factor α. NO: nitric oxide. LNAA: Large, neutral amino acids. BCAA: Branched-chain amino acids. SAE: sepsis-associated encephalopathy. BBB: blood-brain barrier.</p>" ] ] ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "Fernando Godinho Zampieri, Marcelo Park, Fabio Santana Machado, Luciano Cesar Pontes Azevedo" "autores" => array:4 [ 0 => array:2 [ "nombre" => "Fernando Godinho" "apellidos" => "Zampieri" ] 1 => array:2 [ "nombre" => "Marcelo" "apellidos" => "Park" ] 2 => array:2 [ "nombre" => "Fabio Santana" "apellidos" => "Machado" ] 3 => array:2 [ "nombre" => "Luciano Cesar Pontes" "apellidos" => "Azevedo" ] ] ] ] ] "idiomaDefecto" => "en" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1807593222023432?idApp=UINPBA00004N" "url" => "/18075932/0000006600000010/v1_202212011334/S1807593222023432/v1_202212011334/en/main.assets" ] "en" => array:11 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">LETTER TO THE EDITOR</span>" "titulo" => "Further peer review failures" "tieneTextoCompleto" => true "paginas" => array:1 [ 0 => array:1 [ "paginaInicial" => "1833" ] ] "autores" => array:1 [ 0 => array:4 [ "autoresLista" => "Horacio Rivera" "autores" => array:1 [ 0 => array:4 [ "nombre" => "Horacio" "apellidos" => "Rivera" "email" => array:1 [ 0 => "hrivera@cencar.udg.mx" ] "referencia" => array:3 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">I</span>" "identificador" => "aff1" ] 1 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">II</span>" "identificador" => "aff2" ] 2 => array:2 [ "etiqueta" => "*" "identificador" => "cor1" ] ] ] ] "afiliaciones" => array:2 [ 0 => array:3 [ "entidad" => "División de Genética, CIBO, Instituto Mexicano del Seguro Social, Guadalajara, México." "etiqueta" => "I" "identificador" => "aff1" ] 1 => array:3 [ "entidad" => "Genética Humana, CUCS, Universidad de Guadalajara, Guadalajara, México." "etiqueta" => "II" "identificador" => "aff2" ] ] "correspondencia" => array:1 [ 0 => array:3 [ "identificador" => "cor1" "etiqueta" => "*" "correspondencia" => "Tel.: 52 33 3618-9410" ] ] ] ] "textoCompleto" => "<span class="elsevierStyleSections"><p id="para10" class="elsevierStylePara elsevierViewall">Although peer review has been used to maintain the quality of published research, it can be a “seriously flawed” process<a class="elsevierStyleCrossRef" href="#bib1">1</a> and might result in the publication of papers with errors. I refer here to the report<a class="elsevierStyleCrossRef" href="#bib2">2</a> of a de novo (2;16)(q36.3;p13.3) translocation that is associated with Rubinstein-Taybi syndrome (RTS). This report was published in <span class="elsevierStyleItalic">Clinics</span> and contains a cytogenetic mistake in the depicted karyotype. Although the translocation is correct (2;16), the chromosome 2 breakpoint is juxtaposed to the centromere and not at 2q36.3. Thus, the telocentric der (2) is composed of the whole 2q (including the centromere) and is presumably capped with the 16p telomere whereas the whole 2p is attached to 16p13.3. Therefore, the correct karyotype should be written as 46,XX,t(2;16)(p11.2;p13.3)dn. In addition, the assertion by Torres et al.<a class="elsevierStyleCrossRef" href="#bib2">2</a> that their “RTS patient is the third reported case with a de novo t(2;16)(q36.3;p13.3)” is groundless because only one RTS patient with this translocation has been reported.<a class="elsevierStyleCrossRef" href="#bib3">3</a> In a subsequent paper, Torres et al.<a class="elsevierStyleCrossRef" href="#bib4">4</a> have repeated the same cytogenetic error. These remarks further stress that even serious mistakes may be unnoticed during the peer and editorial review process.</p></span>" "pdfFichero" => "main.pdf" "tienePdf" => true "NotaPie" => array:1 [ 0 => array:1 [ "nota" => "<p class="elsevierStyleNotepara" id="cenpara10">No potential conflict of interest was reported.</p>" ] ] "bibliografia" => array:2 [ "titulo" => "REFERENCES" "seccion" => array:1 [ 0 => array:2 [ "identificador" => "cebibsec10" "bibliografiaReferencia" => array:4 [ 0 => array:3 [ "identificador" => "bib1" "etiqueta" => "1" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Quality and peer review of research: an adjudicating role for editors" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => """ DP Newton \n \t\t\t\t\t\t\t\t """ ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1080/08989621003791945" "Revista" => array:7 [ "tituloSerie" => "Account Res" "fecha" => "2010" "volumen" => "17" "paginaInicial" => "130" "paginaFinal" => "145" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/20461569" "web" => "Medline" ] ] "itemHostRev" => array:3 [ "pii" => "S0140673613605954" "estado" => "S300" "issn" => "01406736" ] ] ] ] ] ] ] 1 => array:3 [ "identificador" => "bib2" "etiqueta" => "2" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Rubinstein-Taybi syndrome: a female patient with a de novo reciprocal translocation t(2;16)(q36.3; p13.3) and dysgranulopoiesis" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:6 [ 0 => """ LC Torres \n \t\t\t\t\t\t\t\t """ 1 => """ ML Lopes Chauffaille \n \t\t\t\t\t\t\t\t """ 2 => """ TP Delboni \n \t\t\t\t\t\t\t\t """ 3 => """ TS Okay \n \t\t\t\t\t\t\t\t """ 4 => """ M Carneiro-Sampaio \n \t\t\t\t\t\t\t\t """ 5 => """ S Sugayama \n \t\t\t\t\t\t\t\t """ ] ] ] ] ] "host" => array:2 [ 0 => array:2 [ "doi" => "10.1590/S1807-59322010000100016" "Revista" => array:6 [ "tituloSerie" => "Clinics" "fecha" => "2010" "volumen" => "65" "paginaInicial" => "107" "paginaFinal" => "109" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/20126353" "web" => "Medline" ] ] ] ] 1 => array:2 [ "doi" => "10.1590/S1807-59322010000100016" "WWW" => array:1 [ "link" => "10.1590/S1807-593220100001000016" ] ] ] ] ] ] 2 => array:3 [ "identificador" => "bib3" "etiqueta" => "3" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Rubinstein-Taybi syndrome caused by a de novo reciprocal translocation t(2;16)(q36.3;p13.3)" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => """ F Petrij \n \t\t\t\t\t\t\t\t """ 1 => """ JC Dorsman \n \t\t\t\t\t\t\t\t """ 2 => """ HG Dauwerse \n \t\t\t\t\t\t\t\t """ 3 => """ RH Giles \n \t\t\t\t\t\t\t\t """ 4 => """ T Peeters \n \t\t\t\t\t\t\t\t """ 5 => """ RC Hennekam \n \t\t\t\t\t\t\t\t """ ] ] ] ] ] "host" => array:2 [ 0 => array:2 [ "doi" => "10.1002/(sici)1096-8628(20000501)92:1<47::aid-ajmg8>3.0.co;2-h" "Revista" => array:6 [ "tituloSerie" => "Am J Med Genet" "fecha" => "2000" "volumen" => "92" "paginaInicial" => "47" "paginaFinal" => "52" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/10797422" "web" => "Medline" ] ] ] ] 1 => array:2 [ "doi" => "10.1002/(sici)1096-8628(20000501)92:1<47::aid-ajmg8>3.0.co;2-h" "WWW" => array:1 [ "link" => "10.1002/(SICI)1096-8628(20000501)92:1<47::AID-AJMG8>3.0.CO;2-H" ] ] ] ] ] ] 3 => array:3 [ "identificador" => "bib4" "etiqueta" => "4" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Evaluation of the immune humoral response of Brazilian patients with Rubinstein-Taybi syndrome" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:5 [ 0 => """ LC Torres \n \t\t\t\t\t\t\t\t """ 1 => """ SM Sugayama \n \t\t\t\t\t\t\t\t """ 2 => """ C Arslanian \n \t\t\t\t\t\t\t\t """ 3 => """ MM Sales \n \t\t\t\t\t\t\t\t """ 4 => """ M Carneiro-Sampaio \n \t\t\t\t\t\t\t\t """ ] ] ] ] ] "host" => array:2 [ 0 => array:2 [ "doi" => "10.1590/s0100-879x2010007500119" "Revista" => array:6 [ "tituloSerie" => "Braz J Med Biol Res" "fecha" => "2010" "volumen" => "43" "paginaInicial" => "1215" "paginaFinal" => "1224" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/21085895" "web" => "Medline" ] ] ] ] 1 => array:2 [ "doi" => "10.1590/s0100-879x2010007500119" "WWW" => array:1 [ "link" => "10.1590/S0100-879X2010007500119" ] ] ] ] ] ] ] ] ] ] ] "idiomaDefecto" => "en" "url" => "/18075932/0000006600000010/v1_202212011334/S1807593222023444/v1_202212011334/en/main.assets" "Apartado" => null "PDF" => "https://static.elsevier.es/multimedia/18075932/0000006600000010/v1_202212011334/S1807593222023444/v1_202212011334/en/main.pdf?idApp=UINPBA00004N&text.app=https://www.elsevier.es/" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1807593222023444?idApp=UINPBA00004N" ]
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