Structured respiratory physiotherapy protocol for resolution of atelectasis in pediatric intensive care

array:22 ["pii" => "S1807593224001716" "issn" => "18075932" "doi" => "10.1016/j.clinsp.2024.100494" "estado" => "S250" "fechaPublicacion" => "2024-01-01" "aid" => "100494" "copyright" => "HCFMUSP" "copyrightAnyo" => "2024" "documento" => "article" "crossmark" => 1 "subdocumento" => "fla" "abierto" => array:3 [ "ES" => false "ES2" => false "LATM" => false ] "gratuito" => false "lecturas" => array:1 [ "total" => 0 ] "itemSiguiente" => array:17 [ "pii" => "S1807593224001765" "issn" => "18075932" "doi" => "10.1016/j.clinsp.2024.100499" "estado" => "S250" "fechaPublicacion" => "2024-01-01" "aid" => "100499" "copyright" => "HCFMUSP" "documento" => "article" "crossmark" => 1 "subdocumento" => "fla" "abierto" => array:3 [ "ES" => false "ES2" => false "LATM" => false ] "gratuito" => false "lecturas" => array:1 [ "total" => 0 ] "en" => array:12 [ "idiomaDefecto" => true "cabecera" => "Original articles" "titulo" => "Use of continuous positive airway pressure in drainage of pleural effusion: Educational intervention for evidence-based practice" "tienePdf" => "en" "tieneTextoCompleto" => "en" "tieneResumen" => array:2 [ 0 => "en" 1 => "en" ] "contieneResumen" => array:1 [ "en" => true ] "contieneTextoCompleto" => array:1 [ "en" => true ] "contienePdf" => array:1 [ "en" => true ] "resumenGrafico" => array:2 [ "original" => 0 "multimedia" => array:8 [ "identificador" => "fig0001" "etiqueta" => "Fig. 1" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr1.jpeg" "Alto" => 1481 "Ancho" => 2231 "Tamanyo" => 150043 ] ] "detalles" => array:1 [ 0 => array:3 [ "identificador" => "alt0004" "detalle" => "Fig " "rol" => "short" ] ] "descripcion" => array:1 [ "en" => "Study phases: Phase I, Baseline audit phase; Phase II, Implementation phase; Phase III, Post-intervention audit; Phase IV, Follow-up. CSAT, Clinical Sustainability Assessment Tool." ] ] ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "Elinaldo da Conceição dos Santos, Adilson Mendes, Daniela Gonçalves Ohara, Hiago Vinicius Costa Silva, Jhéssica Crhistina Veiga Nascimento, João Paulo Rodrigues Pacheco, William Poncin, Gregory Reychler, Juliana Ribeiro Fonseca Franco de Macedo, Adriana Claudia Lunardi" "autores" => array:10 [ 0 => array:2 [ "nombre" => "Elinaldo da Conceição dos" "apellidos" => "Santos" ] 1 => array:2 [ "nombre" => "Adilson" "apellidos" => "Mendes" ] 2 => array:2 [ "nombre" => "Daniela Gonçalves" "apellidos" => "Ohara" ] 3 => array:2 [ "nombre" => "Hiago Vinicius Costa" "apellidos" => "Silva" ] 4 => array:2 [ "nombre" => "Jhéssica Crhistina Veiga" "apellidos" => "Nascimento" ] 5 => array:2 [ "nombre" => "João Paulo Rodrigues" "apellidos" => "Pacheco" ] 6 => array:2 [ "nombre" => "William" "apellidos" => "Poncin" ] 7 => array:2 [ "nombre" => "Gregory" "apellidos" => "Reychler" ] 8 => array:2 [ "nombre" => "Juliana Ribeiro Fonseca Franco de" "apellidos" => "Macedo" ] 9 => array:2 [ "nombre" => "Adriana Claudia" "apellidos" => "Lunardi" ] ] ] ] "resumen" => array:1 [ 0 => array:3 [ "titulo" => "Highlights" "clase" => "author-highlights" "resumen" => "<ul class="elsevierStyleList" id="celist0001"><li class="elsevierStyleListItem" id="celistitem0001">•Educational interventions to update healthcare professionals on the importance of CPAP.</li><li class="elsevierStyleListItem" id="celistitem0003">•Continuing education needs to be implemented for better patient care.</li><li class="elsevierStyleListItem" id="celistitem0004">•An educational intervention may have some success in educating and updating healthcare professionals on the use of CPAP in patients with chest tubes due to pleural effusion.</li><li class="elsevierStyleListItem" id="celistitem0005">•Physical therapists need to be strongly encouraged to write down the details of the interventions they perform in patients' medical records.</li><li class="elsevierStyleListItem" id="celistitem0006">•New strategies for continuing education of health professionals need to be developed so that the patient receives the best possible care.</li></ul>" ] ] ] "idiomaDefecto" => "en" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1807593224001765?idApp=UINPBA00004N" "url" => "/18075932/000000790000000C/v115_202410170932/S1807593224001765/v115_202410170932/en/main.assets" ] "itemAnterior" => array:17 [ "pii" => "S1807593224001686" "issn" => "18075932" "doi" => "10.1016/j.clinsp.2024.100491" "estado" => "S250" "fechaPublicacion" => "2024-01-01" "aid" => "100491" "copyright" => "HCFMUSP" "documento" => "article" "crossmark" => 1 "subdocumento" => "fla" "abierto" => array:3 [ "ES" => false "ES2" => false "LATM" => false ] "gratuito" => false "lecturas" => array:1 [ "total" => 0 ] "en" => array:12 [ "idiomaDefecto" => true "cabecera" => "Original articles" "titulo" => "Changes in fluconazole pharmacokinetics can impact on antifungal effectiveness in critically ill burn patients: a Pharmacokinetic-Pharmacodynamic (PK/PD) approach" "tienePdf" => "en" "tieneTextoCompleto" => "en" "tieneResumen" => array:2 [ 0 => "en" 1 => "en" ] "contieneResumen" => array:1 [ "en" => true ] "contieneTextoCompleto" => array:1 [ "en" => true ] "contienePdf" => array:1 [ "en" => true ] "resumenGrafico" => array:2 [ "original" => 0 "multimedia" => array:8 [ "identificador" => "fig0002" "etiqueta" => "Figure 2" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr2.jpeg" "Alto" => 1944 "Ancho" => 2500 "Tamanyo" => 223185 ] ] "detalles" => array:1 [ 0 => array:3 [ "identificador" => "alt0003" "detalle" => "Figure " "rol" => "short" ] ] "descripcion" => array:1 [ "en" => "Fluconazole PK/PD target attainment in the critically ill severely burned patients. (A) AUCss0-24h/MIC. (B) fAUCss0-24h/MIC. Data from this study is presented as median (interquartile range). AUCss0-24h, Area Under the Concentration-time curve of 24h; fAUCss0-24h, Area Under the free Concentration-time curve of 24h; MIC, Minimum Inhibitory Concentration; TDM, Therapeutic Drug Monitoring." ] ] ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "Victor Kaneko Matsuno, Edvaldo Vieira de Campos, Elson Mendes da Silva Junior, João Manoel da Silva Junior, David de Souza Gomez, Silvia Regina Cavani Jorge Santos" "autores" => array:6 [ 0 => array:2 [ "nombre" => "Victor Kaneko" "apellidos" => "Matsuno" ] 1 => array:2 [ "nombre" => "Edvaldo Vieira de" "apellidos" => "Campos" ] 2 => array:2 [ "nombre" => "Elson Mendes da" "apellidos" => "Silva Junior" ] 3 => array:2 [ "nombre" => "João Manoel da" "apellidos" => "Silva Junior" ] 4 => array:2 [ "nombre" => "David de Souza" "apellidos" => "Gomez" ] 5 => array:2 [ "nombre" => "Silvia Regina Cavani Jorge" "apellidos" => "Santos" ] ] ] ] "resumen" => array:1 [ 0 => array:3 [ "titulo" => "Highlights" "clase" => "author-highlights" "resumen" => "<ul class="elsevierStyleList" id="celist0001"><li class="elsevierStyleListItem" id="celistitem0001">•Fluconazole pharmacokinetics is significantly altered in critically ill burn patients.</li><li class="elsevierStyleListItem" id="celistitem0002">•Half-life and total body clearance were correlated to volume of distribution decrease.</li><li class="elsevierStyleListItem" id="celistitem0003">•High-dose fluconazole may be necessary to guarantee coverage against Candida glabrata.</li></ul>" ] ] ] "idiomaDefecto" => "en" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1807593224001686?idApp=UINPBA00004N" "url" => "/18075932/000000790000000C/v115_202410170932/S1807593224001686/v115_202410170932/en/main.assets" ] "en" => array:18 [ "idiomaDefecto" => true "cabecera" => "Original articles" "titulo" => "Structured respiratory physiotherapy protocol for resolution of atelectasis in pediatric intensive care" "tieneTextoCompleto" => true "autores" => array:1 [ 0 => array:4 [ "autoresLista" => "Patrícia Aparecida Silva Camassuti, Cíntia Johnston, Werther Brunow de Carvalho, Michele Luglio, Orlei Ribeiro de Araújo, Brenda Morrow" "autores" => array:6 [ 0 => array:4 [ "nombre" => "Patrícia Aparecida Silva" "apellidos" => "Camassuti" "email" => array:1 [ 0 => "patriciascamassuti@gmail.com" ] "referencia" => array:2 [ 0 => array:2 [ "etiqueta" => "a" "identificador" => "aff0001" ] 1 => array:2 [ "etiqueta" => "*" "identificador" => "cor0001" ] ] ] 1 => array:3 [ "nombre" => "Cíntia" "apellidos" => "Johnston" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "a" "identificador" => "aff0001" ] ] ] 2 => array:3 [ "nombre" => "Werther Brunow" "apellidos" => "de Carvalho" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "b" "identificador" => "aff0002" ] ] ] 3 => array:3 [ "nombre" => "Michele" "apellidos" => "Luglio" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "c" "identificador" => "aff0003" ] ] ] 4 => array:3 [ "nombre" => "Orlei Ribeiro" "apellidos" => "de Araújo" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "d" "identificador" => "aff0004" ] ] ] 5 => array:3 [ "nombre" => "Brenda" "apellidos" => "Morrow" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "e" "identificador" => "aff0005" ] ] ] ] "afiliaciones" => array:5 [ 0 => array:3 [ "entidad" => "Postgraduate Program in Pediatrics, Department of Pediatrics, Universidade de São Paulo, São Paulo, SP, Brazil" "etiqueta" => "a" "identificador" => "aff0001" ] 1 => array:3 [ "entidad" => "Department of Pediatrics, Universidade de São Paulo, São Paulo, SP, Brazil" "etiqueta" => "b" "identificador" => "aff0002" ] 2 => array:3 [ "entidad" => "Children's Institute, Universidade de São Paulo, São Paulo, SP, Braziil" "etiqueta" => "c" "identificador" => "aff0003" ] 3 => array:3 [ "entidad" => "Institute of Pediatric Oncology, Support Group for Adolescents and Children with Cancer (GRAACC), Universidade Federal de São Paulo, São Paulo, SP, Brazil" "etiqueta" => "d" "identificador" => "aff0004" ] 4 => array:3 [ "entidad" => "Department of Paediatrics and Child Health, University of Cape Town: Rondebosch, Western Cape, ZA, South Africa" "etiqueta" => "e" "identificador" => "aff0005" ] ] "correspondencia" => array:1 [ 0 => array:3 [ "identificador" => "cor0001" "etiqueta" => "⁎" "correspondencia" => "Corresponding author." ] ] ] ] "resumenGrafico" => array:2 [ "original" => 0 "multimedia" => array:8 [ "identificador" => "fig0003" "etiqueta" => "Fig. 3" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr3.jpeg" "Alto" => 2967 "Ancho" => 2833 "Tamanyo" => 204203 ] ] "detalles" => array:1 [ 0 => array:3 [ "identificador" => "alt0007" "detalle" => "Fig " "rol" => "short" ] ] "descripcion" => array:1 [ "en" => "Sample selection flowchart." ] ] ] "textoCompleto" => "IntroductionDeveloping lungs are predisposed to collapse.<a class="elsevierStyleCrossRef" href="#bib0001">1</a> Atelectasis is one of the most frequent pulmonary complications in children undergoing Invasive Mechanical Ventilation (IMV).<a class="elsevierStyleCrossRef" href="#bib0002">2</a>Children are at higher risk of atelectasis, owing to both obstruction and dynamic airway collapse, due to their distinct anatomical and physiological features. These predisposing features include smaller diameter, less well-supported airways; flexible/compliant chest walls with relatively less compliant lungs; and limited, developing collateral ventilation channels.<a class="elsevierStyleCrossRef" href="#bib0003">3</a>In Pediatric Intensive Care Units (PICUs), more than 20% of patients require IMV.<a class="elsevierStyleCrossRef" href="#bib0004">4</a> The implementation of protective ventilation strategies with the use of low tidal volumes may, in some cases, contribute to the development of atelectasis secondary to insufficient inflation of the alveolar units.<a class="elsevierStyleCrossRef" href="#bib0004">4</a>In addition, infection of the lower respiratory system is one of the leading causes of mortality in children under the age of five.<a class="elsevierStyleCrossRef" href="#bib0005">5</a> During Lower Respiratory Tract Infections (LRTI), mucociliary clearance may be impaired by increased inflammation and/or overload due to excessive mucus production, with consequent impairment of ciliary function, predisposing these patients to secondary complications such as pulmonary atelectasis.<a class="elsevierStyleCrossRef" href="#bib0006">6</a>Lung collapse may cause or exacerbate increased work of breathing, hypoxemia, hypercapnia, and acute respiratory failure (mild, moderate, or severe).<a class="elsevierStyleCrossRef" href="#bib0007">7</a> Long-term complications of unresolved atelectasis include the development of bronchiectasis and chronic lung disease. Early recognition and management of atelectasis are therefore essential to hasten resolution, avoid adverse short and long-term sequelae, and optimize clinical outcomes such as PICU and hospital length of stay and mortality.<a class="elsevierStyleCrossRef" href="#bib0008">8</a>The signs and symptoms of pulmonary atelectasis are often nonspecific, however, the application of imaging technologies has increased diagnostic sensitivity and specificity.<a class="elsevierStyleCrossRef" href="#bib0009">9</a> Although chest X-Ray is still the gold standard for diagnosing atelectasis, due to its cost and effectiveness,<a class="elsevierStyleCrossRef" href="#bib0010">10</a> it has significant limitations including patient exposure to ionizing radiation, relatively low sensitivity in detecting inflammatory lung lesions, low negative predictive value, and discrepancies in interpretation among specialists.<a class="elsevierStyleCrossRef" href="#bib0011">11</a>In view of the limitations of radiography, the use of Point of Care Lung Ultrasound (POCLUS) has been proposed as an additional tool for identifying and monitoring pulmonary atelectasis in children. Among the advantages are the low associated financial costs; clinical utility of trained healthcare professionals being able to easily and quickly perform the test at the bedside; and avoidance of harmful ionizing radiation, allowing multiple repeated scans if needed to determine progression and/or response to therapy.<a class="elsevierStyleCrossRef" href="#bib0012">12</a>The interventions used in the treatment of pulmonary atelectasis in intubated children are limited and, to date, there are no clinical trials that identify the most efficient treatment for the resolution of pulmonary atelectasis in pediatrics and neonatology.<a class="elsevierStyleCrossRef" href="#bib0009">9</a>Chest physiotherapy in patients with pulmonary atelectasis is a minimally invasive treatment that aims to maintain or improve airway patency by removing obstructive secretions, reducing airway resistance, promoting gas exchange, and decreasing the work of breathing.<a class="elsevierStyleCrossRef" href="#bib0013">13</a>Although respiratory physiotherapy interventions include several techniques for the treatment of atelectasis, there are only four studies<a class="elsevierStyleCrossRefs" href="#bib0014">14–17</a> that cite different methods of respiratory physiotherapy aimed at resolving atelectasis in pediatric patients on IMV. However, none of them are randomized controlled trials and none use standardized, protocol-driven interventions.Therefore, the main objective of this study was to develop and analyze the clinical and imaging effects of a Structured Respiratory Physiotherapy Protocol (SRRP) for airway clearance and lung reexpansion in children on IMV diagnosed with unilateral pulmonary atelectasis.Materials and methodsStudy design and populationThis was a prospective randomized controlled clinical trial, registered in the Brazilian Clinical Trials Registry (ReBEC): RBR-106bhfwy, carried out in the PICU of the Menino Jesus Municipal Children's Hospital (HMIMJ), in São Paulo, from October 2020 to March 2022. The study was approved by the Research Ethics Committee of the University of São Paulo School of Medicine (FMUSP) and by the Research Ethics Committee of the HMIMJ (opinion 3,689,413). The study started after its approval.The study included 30 infants (age: 28 days to 24 months) on IMV for a period greater than or equal to 12 hours through an orotracheal cannula, diagnosed with pulmonary atelectasis by a pediatric intensive care physician through clinical examination and imaging (chest X-Ray and POCLUS), whose legal guardians had authorized the child's participation in the study through the Free and Informed Consent Form (ICF). Exclusion criteria included: patients with bilateral atelectasis; any type of air leak syndrome; pulmonary hemorrhage; presence of diseases presenting with bone fragility; rib cage and/or pulmonary contusions; subcutaneous pacemakers; treatment with anticoagulants for more than 72 continuous hours; hemodynamic instability; thrombocytopenia (platelet count < 50,000); presence of an intercostal chest drain; underlying neuromuscular or cardiac diseases and presence of spinal deformities.Patients who met the inclusion criteria were electronically randomized (<a href="https://www.random.org/lists/">https://www.random.org/lists/</a>) into two groups: Control Group (CG) and Intervention Group (IG) as described in <a class="elsevierStyleCrossRef" href="#fig0001">Fig. 1</a>.<elsevierMultimedia ident="fig0001"></elsevierMultimedia>The sample size was calculated based on historical audit data from the study site ‒ between August and December 2018, 49 patients underwent tracheal intubation in this PICU, with 13 of these patients developing pulmonary atelectasis. It was therefore estimated that over a period of 12 months, approximately 26‒30 patients would develop pulmonary atelectasis. When entered into a power analysis (using the statistical program openepi.com), with equal numbers in the Intervention (IG) and Control (CG) groups, a sample of 30 patients (15 each in IG and CG) yielded a statistical power of 80%, with 20% error.In order to characterize the sample, the following data were collected from the patient's medical records: age, gender, clinical diagnosis of hospitalization, weight, height, laboratory tests, and the Pediatric Index of Mortality 2 (PIM 2) outcome prediction score.Data collection was performed by the physical therapist responsible for the study. Upon detecting the presence of atelectasis on the chest X-Ray, the pediatric intensive care physician responsible for the PICU called the physical therapist via cell phone. After the activation, the researcher checked whether the patient met the inclusion criteria of the study. If so, the authorization of the legal guardian was requested to allow the child's participation in the study through the informed consent form. After signing the informed consent form, the patient was electronically randomized into CG or IG.Chest X-rayThe baseline anteroposterior radiological images were considered to be free of atelectasis when there was normal pulmonary transparency with free costophrenic sinuses visualized. Lobar or segmental atelectasis was considered when opacification of the lobe or lung segment was present with any of the following concomitant signs: loss of air/gas volume, the most direct sign being the displacement of the interlobar fissure; the deviation of the heart and mediastinum and the elevation of the diaphragm to the same side as atelectasis in extensive collapse.<a class="elsevierStyleCrossRef" href="#bib0017">18</a>The Radiological Atelectasis Scoring System was used to score atelectasis observed on lung X-Rays.<a class="elsevierStyleCrossRef" href="#bib0018">19</a> Each radiograph was scored by the physiotherapist for atelectasis, hyperinflation, and mediastinal displacement. The presence or absence of pulmonary hyperinflation was each marked as one (1) point or zero (0) points, respectively. The presence or absence of a mediastinal deviation was scored as one (1) or zero (0). Atelectasis was scored for each lung lobe. Partial atelectasis of one lung lobe was scored as one (1) point, and complete atelectasis of one lobe was scored as two (2) points. The scores were summed for the chest X-Ray of each patient.Point of care lung ultrasound (POCLUS)Lung ultrasound was performed immediately before initiating interventions (baseline) and repeated 30 minutes after intervention (post-intervention measure). The assessment was performed by the main researcher, a physiotherapist trained and certified to perform lung ultrasound. The POCLUS images were recorded and subsequently analyzed by an independent evaluator blinded to study allocation and patient history. The independent evaluator was a pediatric intensive care physician with ultrasonography certification and extensive clinical experience over more than eight years.The lung was scanned antero-posteriorly, craniocaudally, transversely, and longitudinally to the costal arches. Initially, POCLUS was performed with the patient in the supine position and subsequently turned laterally to evaluate the posterior pulmonary region.The ultrasound image was considered unaltered when it showed an association between pleural sliding and the presence of horizontal repeats of the pleural line called “A-lines”. A-lines are a type of reflection artifact originating from the pleural line, seen as a series of hyperechoic parallel lines, equidistant from each other, below the pleural line, with spacing equal to the distance between the skin and the pleural line.<a class="elsevierStyleCrossRef" href="#bib0012">12</a>The main imaging characteristics of atelectasis visualized by ultrasound are loss of aeration generating a visible, hyperechoic parenchymal area, which may present ill-defined and irregular borders; large lung consolidations with static bronchograms; whilst dynamic air bronchogram can rule out atelectasis.<a class="elsevierStyleCrossRef" href="#bib0019">20</a> Other signs of atelectasis on POCLUS include abnormalities in the pleural line and disappearance of the A-line.<a class="elsevierStyleCrossRef" href="#bib0020">21</a> The coalescent B-line (or B-pattern) can be interpreted as a higher degree of severity or a state prior to the development of atelectasis, especially if the lesion has a focal location.<a class="elsevierStyleCrossRef" href="#bib0021">22</a> The B-lines are hyperechoic vertical artifacts originating from the pleural line that extends to the periphery of the lung field and move with the pulmonary sliding.<a class="elsevierStyleCrossRef" href="#bib0022">23</a> At the point of intersection, the B-lines obliterate the A-lines.The loss of lung aeration identified at POCLUS was graded using the Lung Ultrasound Score (LUS), validated for this purpose.<a class="elsevierStyleCrossRef" href="#bib0023">24</a> A score of 0 indicates normal aeration i.e., the presence of lung slippage and horizontal A-lines, or less than three vertical B-lines; a score of 1 indicates moderate loss of aeration indicated by the presence of ≥3 B-lines, regularly or irregularly spaced, originating from the pleural line or small juxta pleural consolidations; a score of 2 indicates severe loss of aeration, i.e.; the presence of coalescing B-lines in several intercostal spaces, occupying the entire intercostal space; and a score of 3 indicates complete loss of pulmonary aeration, characterized by the presence of tissue echogenicity and static or dynamic air bronchograms, as observed in lung consolidation.MonitoringPatients in both groups had vital sign measurements assessed at baseline (immediately before intervention) and at 10 and 30 minutes after intervention: and underwent three evaluations Heart Rate (HR); Respiratory Rate (RR); body temperature; PA; SpO2. Clinical severity was classified according to the Wood-Downes Score (WD)<a class="elsevierStyleCrossRef" href="#bib0024">25</a> as mild (1 to 3 points), moderate (4 to 7 points) and severe (8 to 14 points) according to the sum of the following items: the presence of wheezing (0 = No; 1 = End of expiration; 2 = Full expiration; 3 = Inhalation and expiration); the presence of chest indrawing (No = 0; Subcostal = 1; Supraclavicular subcostal and nasal flare = 2; supraclavicular, subcostal, intercostal, suprasternal, and nasal flare = 3); total respiratory rate (< 30 breaths per minute = 0; 31‒45 = 1; 46‒60 = 2; > 60 = 3); heart rate (< 120 beats per minute = 0; > 120 = 1); ventilation and breath sound on auscultation (0 = Good and symmetrical breath sounds; 1 = Regular and symmetrical; 2 = Very decreased breath sounds; 3 = Silent chest and cyanosis (0 = No; 1 = Yes).During monitoring, the number of aspirations, quantity, and quality of aspirated tracheal secretion were recorded, according to the Suzukava Method:<a class="elsevierStyleCrossRef" href="#bib0025">26</a> Fluid when the aspiration tube is free of secretions after aspiration, using only vacuum; Moderate, when the aspiration tube presents secretions adhered to the wall of the probe after aspiration but is free after the use of 0.9% saline solution; Thick, when the aspiration probe has secretions adhered to the probe wall even after instillation of 0.9% saline solution.Control groupThe CG was submitted to routine respiratory physiotherapy care and interventions of the Physical Therapy Service, including manual vibration of the patient's chest wall and Manual Hyperinflation (MH) with a self-inflating bag without control of Peak Inspiratory Pressure (PIP), number of repetitions or established intervals.The technique of manual vibration in the chest is based on the properties of modifying the consistency of airway mucus. This thixotropic gel, highly viscous under static conditions can become less viscous and is able to flow when shaken.<a class="elsevierStyleCrossRef" href="#bib0026">27</a> Thus, when applying vibrations to the chest wall, mechanical energy is transmitted to the airways aiding the ciliary beating, thus reducing the viscosity of bronchial secretions, which can be more easily eliminated by positioning, coughing, or aspiration of the airways.<a class="elsevierStyleCrossRef" href="#bib0027">28</a>Manual Hyperinflation (MH) aims to mobilize pulmonary secretions proximally by increasing Peak Expiratory Flow (PEF) and promoting pulmonary re-expansion by increasing pulmonary distension pressure, which favors increased airflow to the poorly ventilated regions through the collateral channels (where present) and by redistributing and renewing surfactant in the alveoli.<a class="elsevierStyleCrossRef" href="#bib0028">29</a> The technique is performed by applying a series of deep manual insufflations with brief inspiratory pauses, followed by a rapid release of the bag to increase expiratory flow and stimulate coughing.<a class="elsevierStyleCrossRef" href="#bib0027">28</a>Intervention groupThe IG was submitted only to the SRPP developed for this study and applied by the main research physiotherapist. The SRPP intervention included modified postural drainage with mechanical chest wall vibration applied using an electronic massage device (Super da G-Life®); MH using a self-inflating bag; stretching of the respiratory muscles; and functional positioning of the patient in bed.The patient was first positioned with elevation of the head of the bed by 30° in lateral decubitus, so that the atelectatic pulmonary region was non-dependent, maintaining this position during the application of the other interventions.Mechanical vibration over the chest wall was performed with the use of a massager positioned over the atelectatic region, in the craniocaudal and lateromedial directions, for ten minutes, with a frequency of 50 Hertz (Hz).<a class="elsevierStyleCrossRef" href="#bib0015">15</a> Manual hyperinflation with a self-inflating bag consisted of slow and deep inflation of the bag, followed by an inspiratory pause of two to three seconds and rapid release after this period<a class="elsevierStyleCrossRef" href="#bib0028">29</a> with oxygen flow at five liters per minute, with 10 repetitions.<a class="elsevierStyleCrossRef" href="#bib0014">14</a> To monitor the PIP provided during MH, a Murenas® analog manometer was used, not exceeding the PIP of 30 cm H2O.<a class="elsevierStyleCrossRef" href="#bib0028">29</a> No PEEP valve was used.After performing MH, the patients’ accessory respiratory muscles were stretched by the physiotherapist throughout the expiratory phase, bringing the muscle to maximum length, with two sets in 10 consecutive respiratory cycles for each muscle, with a five-second interval between each set.<a class="elsevierStyleCrossRef" href="#bib0029">30</a> The stretches were performed bilaterally as follows: upper trapezius: with the patient positioned in the dorsal decubitus position, the physiotherapist rested one hand on the occipital region, side flexing the head to the opposite side whilst, with the other hand, moving the ipsilateral shoulder in the craniocaudal direction; sternocleidomastoid: with the patient positioned in the dorsal decubitus position, the physiotherapist passively flexed (away from the muscle to be stretched) and laterally rotated towards the target muscle, by placing one hand in the occipital region and the other on the upper thorax region, displacing in the craniocaudal direction; pectoralis major: with the patient positioned in dorsal decubitus, with the arm to be stretched abducted and externally rotated at the shoulder, with elbow flexion, the physiotherapist applied a passive stretch by applying pressure using one hand on the upper third of the arm and the other on the lateral region of the upper thorax, following the orientation of the muscle fibers; intercostal muscles: with the patient in lateral decubitus with the forearm flexed and the hand resting on the occiput, the physiotherapist supported the patient's arm with one hand while the other was positioned on the lower rib cage during inspiration; the physiotherapist facilitated expansion of the rib cage by moving the patient's arm in the craniocaudal direction and following the expiratory movement without applying pressure (<a class="elsevierStyleCrossRef" href="#fig0002">Fig. 2</a>).<a class="elsevierStyleCrossRef" href="#bib0029">30</a><elsevierMultimedia ident="fig0002"></elsevierMultimedia>In both groups, the orotracheal tube was aspirated, when necessary, after the interventions and during the procedures. The quantity and quality of aspirated tracheal secretion were classified using the Suzukava method.<a class="elsevierStyleCrossRef" href="#bib0025">26</a>Finally, functional positioning was performed in bed, aiming to favor respiratory mechanics, optimize pulmonary function, and stimulate the child's sensorineural and psychomotor development.Interrupt criteriaThe criteria for interruption of the protocol were: Heart Rate (HR) greater than 200 beats per minute (bpm); Respiratory Rate (RR) greater than 45 breaths per minute (bpm); Blood Pressure (BP) values above 120/80 millimeters of mercury (mmHg) or less than 80/40 mmHg; Pulse Oxygen Saturation (SpO2) less than 88% with the need for increased FiO2 during the application of the protocol. The presence or absence of signs of respiratory distress (accessory respiratory muscle use, pallor, sweating, and psychomotor agitation) was also considered according to the Wood-Downes Score (WD) used in this study.<a class="elsevierStyleCrossRef" href="#bib0025">26</a> In the presence of any changes mentioned above, the protocol was interrupted, and the child was placed in bed and kept under monitoring. The patient who needed to interrupt the procedures could be included again in the study six hours after interrupting the first attempt. Daily attempts could be made, within 48 hours of the first attempt, after this period the patient was considered as not benefiting from the study protocol.Statistical analysisDescriptive statistics included measures of central tendency by means ± Standard Deviations (SD), medians and interquartile ranges (IQR 25%‒75%), and absolute and relative frequencies.The Kolmogorov-Smirnov test was used to evaluate the normality of the distribution, and considering that most variables were not normally distributed, between-group analyses were conducted using the non-parametric Wilcoxon/Mann-Whitney tests. Fisher's exact tests were used for comparisons between frequencies. To compare repeated vital sign measurements (before physical therapy, after 10 and 30 minutes), the non-parametric Friedman test was used, with post-hoc analysis using the paired Wilcoxon test (signed rank). Bonferroni correction was used as appropriate.Evaluation of the magnitude of the effect (effect size)The intervention of the study was not compared to a placebo, but to a control group, in which routine physical therapy of the Hospital was performed. Therefore, statistical differences were not expected in the two groups when comparing parameters before and after respiratory therapy, and the only way to evaluate the outcome of the study intervention is through the magnitude of the effect (effect size). The standardized effect magnitude allows researchers to communicate the practical significance of the results, rather than just reporting statistical significance.<a class="elsevierStyleCrossRef" href="#bib0030">31</a> Cohen's “d” test (Cohens' d) is used to describe the standardized mean difference of an effect. A correction of Cohens' d is Hedges' “g” (Hedges' g), which is unbiased and corrected for small samples (n < 20), and it was this test that the authors used to measure the effect of the intervention on the LUS and Wood Downes scores (paired measures before and after respiratory physiotherapy). The way to interpret the Hedges' g is as suggested by Cohen: small (0.2 < Hedges' g < 0.5), moderate (0.5 < Hedges' g < 0.8), and large (Hedges' g ≥ 0.8 effects).<a class="elsevierStyleCrossRef" href="#bib0030">31</a> These values assume negative values when the effect is reduced, e.g., a reduction in a score; but they can be informed by their absolute values. If the absolute value is greater than one (1), it means that the difference between the means is greater than one SD.The analyses were performed using R: A language and environment for statistical computing. R Foundation for Statistical Computing, Vienna, Austria. URL <a href="https://www.R-project.org/">https://www.R-project.org/</a>.ResultsDuring the study period, 845 children were admitted to the PICU of the HMIMJ, of which 26% underwent orotracheal intubation and 7% developed pulmonary atelectasis. Of these children, 40 met the inclusion criteria due to atelectasis, 10 patients were excluded (one with scoliosis, two with orotracheal tube displacement, tissue trauma, air leak syndrome (pneumothorax or pneumomediastinum) (<a class="elsevierStyleCrossRef" href="#fig0003">Fig. 3</a>).<elsevierMultimedia ident="fig0003"></elsevierMultimedia>The sample of 30 children was randomized into two groups (n = 15 in the CG; n = 15 in the IG). The median (IQR 25%‒75%) age of the patients was 7 (2‒17) months in the CG and 4 (2‒13.5) months in the IG. The groups presented similar characteristics (p > 0.05) in terms of epidemiology and clinical variables (<a class="elsevierStyleCrossRef" href="#tbl0001">Table 1</a>).<elsevierMultimedia ident="tbl0001"></elsevierMultimedia>Laboratory parameters prior to respiratory therapy interventions were statistically similar (p > 0.05), see <a class="elsevierStyleCrossRef" href="#tbl0001">Table 1</a>. Ventilatory parameters and Radiological Atelectasis Scoring System scores of both groups were similar (p > 0.05), see <a class="elsevierStyleCrossRef" href="#tbl0002">Table 2</a>. Regarding the variables diagnostics, viral panel, IMV mode, VAP, location of atelectasis, quality and color of secretion, it was not possible to add statistical significance due to the small sample size in the subcategories of each of them.<elsevierMultimedia ident="tbl0002"></elsevierMultimedia>Evaluation of lung ultrasound score (LUS) and Wood-Downes (WD) scoresThere was no significant difference in the baseline or post-intervention median (IQ 25%‒75%) LUS scores between the control and intervention groups: 2 (1‒3) vs. 3 (2‒3) (p = 0.21) and 1 (1‒2.5) vs. 1 (0.5‒2) (p = 0.5) respectively. Similarly, there were no significant between-group differences in the median (IQ 25%‒75%) baseline or post-intervention WD scores between CG and IG: 4 (3‒5) vs. 4 (3‒5) (p = 0.9) and 3 (2‒3) vs. 2 (1–2.5) (p = 0.18), respectively.Significant within-group differences were observed in both CG and IG comparing baseline to post-intervention measures (<a class="elsevierStyleCrossRef" href="#tbl0003">Table 3</a>). Median (IQR 25%‒75%) LUS in the CG and IG changed from 2(1–3) and 3 (2–3) before respiratory physiotherapy to 1 (1–2.5; p = 0.01) and 1 (0.5–2; p < 0.001) after intervention respectively. Median (IQ 25%–75% WD score changed from 4 (3.5‒5) and 4 (3–5) to 3(2–3; p < 0.001) and 2 (1–2.5; p < 0.001) postintervention in the control and intervention groups respectively.<elsevierMultimedia ident="tbl0003"></elsevierMultimedia>Assessment of the magnitude of the effectThere was a moderate effect on the reduction of the LUS score in the CG after respiratory physiotherapy (Hedges' g = -0.64, 95% CI: -1.35 to 0.08), and a 2.9-fold greater effect on the IG (Hedges' g = -1.88, 95% CI: -1.01 to -2.73), characterizing a large effect on the reduction of this score (<a class="elsevierStyleCrossRef" href="#fig0004">Fig. 4</a>).<elsevierMultimedia ident="fig0004"></elsevierMultimedia>There was a large effect on the reduction of the WD score in the CG after physical therapy (Hedges' g = -1.53, 95% CI -3.1 to -1.29), and a 1.4-fold greater effect in the IG (Hedges' g = -2.2, 95% CI: -2.32 to -0.71) (<a class="elsevierStyleCrossRef" href="#fig0005">Fig. 5</a>).<elsevierMultimedia ident="fig0005"></elsevierMultimedia>Evaluation of effects on physiological parametersThe parameters of heart rate, respiratory rate, temperature, SpO2, systolic, mean, and diastolic blood pressure at all measurement points were statistically similar between CG and IG (<a class="elsevierStyleCrossRef" href="#tbl0004">Table 4</a>).<elsevierMultimedia ident="tbl0004"></elsevierMultimedia>DiscussionThe loss of lung volume caused by atelectasis can modify respiratory mechanics and impair gas exchange, which can lead to an increase in IMV time, tracheal extubation failure, increased length of hospital stays, and morbidity and mortality.<a class="elsevierStyleCrossRef" href="#bib0031">32</a> This study, including children undergoing IMV, evaluated the effectiveness of a Structured Respiratory Physical Therapy Protocol (SRPP) by means of immediate evaluation by pulmonary ultrasonography compared to a control group aimed at airway clearance and pulmonary re-expansion of atelectasis areas.This is not the first study to report the use of physiotherapist-applied non-invasive interventions to treat pulmonary atelectasis in children on IMV. However, this is the first study to develop and evaluate an SRPP for the resolution of unilateral pulmonary atelectasis in children.In both intervention and control groups, the most frequent location of pulmonary atelectasis was the right upper lobe, which has been described previously.<a class="elsevierStyleCrossRefs" href="#bib0015">15,16</a> This finding can be explained anatomically by the fact that the right upper lobe bronchus is at a 90-degree angle from the right main bronchus, limiting secretion drainage.<a class="elsevierStyleCrossRef" href="#bib0032">33</a>As described in the study by Galvis et al.,<a class="elsevierStyleCrossRef" href="#bib0014">14</a> the factors that may have contributed to the development of atelectasis in these patients in addition to the anatomical and physiological features typical of the pediatric age group include factors related to the health status and critical care modalities. These may include alteration of mucociliary transport, resulting from the artificial airway, mucosal edema and/or excessive mucus production due to trauma associated with repeated suctioning; thickening of mucus caused by the disease process, fluid restriction and diuretic use; accumulation of secretions resulting from inadequate bronchial drainage, particularly in children receiving excessive sedation and neuromuscular blockade; inadequate humidification of inspired gas and incomplete removal of tracheal secretions during tracheal aspiration.<a class="elsevierStyleCrossRef" href="#bib0033">34</a>Previous studies<a class="elsevierStyleCrossRefs" href="#bib0014">14–17</a> on this topic have used chest X-Rays as the primary tool to evaluate the resolution of pulmonary atelectasis and the efficacy of treatments. By offering diagnostic accuracy similar to chest radiography, without exposure to ionizing radiation, POCLUS is a dynamic and agile tool to perform and interpret lung changes, quickly integrating the information into the patient's clinical context.<a class="elsevierStyleCrossRef" href="#bib0034">35</a> Ultrasound was successfully used in this study to evaluate the outcome of respiratory physiotherapy interventions performed in children on IMV with pulmonary atelectasis, which was detected in the first evaluation by means of radiological imaging, evaluated by the intensive care physician.Bedside lung ultrasound is a diagnostic tool that has been increasingly used in Intensive Care Units (ICU), because it is a safe test for both the patient and the team, and can be performed frequently at the bedside by adequately trained PICU professionals, including physiotherapists, allowing non-invasive monitoring of progression and response to therapeutic interventions accurately, quickly, safely and dynamically.<a class="elsevierStyleCrossRef" href="#bib0034">35</a> Although the authors cannot comment on the sensitivity, specificity or reliability of POCLUS in this context, as post-intervention images were not compared with chest X-Ray findings, owing to ethical and resource limitations, and between-rater comparison was not made, previous studies have reported that lung ultrasound is highly reliable both sensitive and specific in identifying and quantifying pathological changes, including atelectasis.<a class="elsevierStyleCrossRefs" href="#bib0012">12,21</a> Although further studies are needed, this study supports the feasible and potential utility of using POCLUS to determine short-term responses to chest physiotherapy interventions.In addition to the evaluation, the LUS<a class="elsevierStyleCrossRef" href="#bib0023">24</a> was used to quantitatively classify the POCLUS image before and after respiratory physiotherapy interventions in both groups. Adult and neonatal clinical practice experts have suggested that clinical evaluation plus semi-quantification of ultrasound scores can be used as a tool to quantify peripheral lung aeration and clinical severity of the patient.<a class="elsevierStyleCrossRef" href="#bib0035">36</a> This approach is based on the hypothesis that the lower the peripheral lung expansibility (areas visualized by the POCLUS), the fewer lung areas will be available for gas exchange.<a class="elsevierStyleCrossRef" href="#bib0036">37</a> Therefore, it is expected that the clinical manifestations of these pulmonary alterations will be more severe.Faced with this hypothesis, a retrospective study,<a class="elsevierStyleCrossRef" href="#bib0036">37</a> including 74 children from zero to 12 months of age, diagnosed with bronchiolitis, and admitted to PICUs, developed a simple and rapid score that combines clinical data (presence of wheezing and reduced oral intake) and ultrasound data (involvement of the right posterior upper pulmonary zone) to predict, during the first evaluation, the need for hospitalization in the PICU, as well as the indication of ventilatory support with CPAP (continuous airway pressure).However, one of the limitations of the study was the absence of patients on IMV.In the present study, although there were large within-group effect sizes, no significant between-group differences were observed in the clinical (WD)<a class="elsevierStyleCrossRef" href="#bib0024">25</a> or Ultrasonographic (LUS)<a class="elsevierStyleCrossRef" href="#bib0023">24</a> scores before versus after respiratory physiotherapy intervention. This suggests that both IG and CG interventions were associated with an improvement in pulmonary imaging (partial or total resolution of pulmonary atelectasis) and in the children's breathing patterns. The magnitude of the treatment effect was, however, greater in the intervention group, suggesting that the protocolized intervention may be more effective at resolving atelectasis in mechanically ventilated children. This requires confirmation in a larger sample study.The application of mechanical thoracic vibration in the IG may have been one of the factors related to the better findings in the reduction of WD and LUS scores in this group. The natural frequency of ciliary beats in mammals is 13 Hz, an increase in bronchial clearance is observed when vibrations reach frequencies between 11 and 15 Hz.<a class="elsevierStyleCrossRef" href="#bib0037">38</a> In the range between 20 and 45 Hz, vibration produces relaxation of the respiratory muscles, verified by a decrease in respiratory rate and an increase in tidal volume.<a class="elsevierStyleCrossRef" href="#bib0037">38</a> The mechanical vibration apparatus used in the study provides a continuous frequency of 50 Hz and, therefore, may have been one of the factors related to the better findings in the intervention group. Bilan et al.<a class="elsevierStyleCrossRef" href="#bib0015">15</a> used mechanical vibration in some patients in their study for 10 to 20 minutes, and there was no comparison between the interventions or the description of the frequency in Hz used.Another intervention included in the SRPP, which may have influenced the resolution of pulmonary atelectasis, is the stretching of the accessory respiratory muscles. The stretching of a muscle fiber promotes an increase in the number of sarcomeres in series. The addition of muscle strength due to stretching is possibly due to the better interaction between actin and myosin filaments.<a class="elsevierStyleCrossRef" href="#bib0038">39</a> Thus, the stretching of the respiratory muscles may have helped in the better performance of the inspiratory and expiratory muscles and increased thoracic expansion and may have contributed to the improvement of respiratory mechanics and to an increase in lung volumes.Another intervention included in the SRPP, which may have contributed to better results in the intervention group, is manual hyperinflation with a self-inflating bag performed in a standardized manner. Regarding the form of MH application, only one study<a class="elsevierStyleCrossRef" href="#bib40">17</a> explained how the intervention was applied (first, slow insufflation, followed by an inspiratory pause of two to three seconds, followed by rapid pressure release), and was performed in the same way in the present study, with the objective of promoting an increase in Peak Expiratory Flow (PEF), displacing secretion to the central airways and simulating the effect of coughing.<a class="elsevierStyleCrossRef" href="#bib0028">29</a>,<a class="elsevierStyleCrossRef" href="#bib0039">40</a> As a safety measure to avoid baro and volutrauma, both the present study and the studies by Galvis et al.<a class="elsevierStyleCrossRef" href="#bib0014">14</a> and Herrada et al.<a class="elsevierStyleCrossRef" href="#bib40">17</a> used a manometer during MH to limit Peak Inspiratory Pressure (PIP) between 30‒35 cm H2O.Regarding the safety of the interventions proposed by the SRPP, vital signs are important, as they allow the rapid identification of clinical deterioration of patients before, during, or after physiotherapy interventions.<a class="elsevierStyleCrossRef" href="#bib0028">29</a> In the present study, vital signs in both groups were statistically similar before and after respiratory physiotherapy. It was not necessary to interrupt the interventions in any of the groups, demonstrating that they do not cause risks of clinical deterioration (bradycardia or tachycardia, tachypnea, drop in SpO2 or changes in blood pressure) to the patients included in the study, being safe in this context. The retrospective study by Herrada et al.<a class="elsevierStyleCrossRef" href="#bib40">17</a> also reported that the respiratory physiotherapy interventions were well tolerated and that although all patients presented with tachycardia after the interventions, none of them presented with significant hemodynamic consequences that required medical intervention.Among the limitations of this study are: a) The SRPP was performed only once, and the patient was not followed up after 30 minutes. Therefore, it was not possible to evaluate maintenance of any clinical or ultrasound improvements, nor the impact on meaningful clinical outcomes such as duration of IMV or PICU length of stay; b) The US findings were not compared to chest X-Ray, so you cannot comment on sensitivity or specify or the tool in this context; c) Variables with several sub-variables did not allow comparison due to the number of cases; d) Due to COVID-19, one of the PICUs in the institution where the study took place was closed, due to the low demand of pediatric patients during this period, making it possible to reach the planned sample size of the study, but over a longer period of data collection.There are still challenges to be faced for the implementation of POCLUS in the routine of physical therapists, such as the provision of skills training, mentoring, and support from experienced mentors. It is a tool that can optimize the functional diagnosis made by the physiotherapist, as well as guide the interventions that may be proposed. Further research is needed to identify the impact of the inclusion of ultrasound in the clinical decision-making of physiotherapists.It is suggested that SRPP be applied to larger samples and with longitudinal follow-up to confirm its benefits in the medium and long term, as well as to compare component interventions to identify which one has the greatest impact on the resolution of pulmonary atelectasis in children on IMV.ConclusionThis study has shown that the Structured Respiratory Physical Therapy Protocol appears to be safe and may be effective in improving airway clearance and lung re-expansion in children on IMV with unilateral pulmonary atelectasis." "textoCompletoSecciones" => array:1 [ "secciones" => array:9 [ 0 => array:3 [ "identificador" => "xres2273470" "titulo" => "Highlights" "secciones" => array:1 [ 0 => array:1 [ "identificador" => "abss0001" ] ] ] 1 => array:3 [ "identificador" => "xres2273469" "titulo" => "Abstract" "secciones" => array:1 [ 0 => array:1 [ "identificador" => "abss0002" ] ] ] 2 => array:2 [ "identificador" => "xpalclavsec1894827" "titulo" => "Keywords" ] 3 => array:2 [ "identificador" => "sec0001" "titulo" => "Introduction" ] 4 => array:3 [ "identificador" => "sec0002" "titulo" => "Materials and methods" "secciones" => array:9 [ 0 => array:2 [ "identificador" => "sec0003" "titulo" => "Study design and population" ] 1 => array:2 [ "identificador" => "sec0004" "titulo" => "Chest X-ray" ] 2 => array:2 [ "identificador" => "sec0005" "titulo" => "Point of care lung ultrasound (POCLUS)" ] 3 => array:2 [ "identificador" => "sec0006" "titulo" => "Monitoring" ] 4 => array:2 [ "identificador" => "sec0007" "titulo" => "Control group" ] 5 => array:2 [ "identificador" => "sec0008" "titulo" => "Intervention group" ] 6 => array:2 [ "identificador" => "sec0009" "titulo" => "Interrupt criteria" ] 7 => array:2 [ "identificador" => "sec0010" "titulo" => "Statistical analysis" ] 8 => array:2 [ "identificador" => "sec0011" "titulo" => "Evaluation of the magnitude of the effect (effect size)" ] ] ] 5 => array:3 [ "identificador" => "sec0012" "titulo" => "Results" "secciones" => array:3 [ 0 => array:2 [ "identificador" => "sec0013" "titulo" => "Evaluation of lung ultrasound score (LUS) and Wood-Downes (WD) scores" ] 1 => array:2 [ "identificador" => "sec0014" "titulo" => "Assessment of the magnitude of the effect" ] 2 => array:2 [ "identificador" => "sec0015" "titulo" => "Evaluation of effects on physiological parameters" ] ] ] 6 => array:2 [ "identificador" => "sec0016" "titulo" => "Discussion" ] 7 => array:2 [ "identificador" => "sec0017" "titulo" => "Conclusion" ] 8 => array:1 [ "titulo" => "References" ] ] ] "pdfFichero" => "main.pdf" "tienePdf" => true "fechaRecibido" => "2023-11-22" "fechaAceptado" => "2024-08-25" "PalabrasClave" => array:1 [ "en" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Keywords" "identificador" => "xpalclavsec1894827" "palabras" => array:5 [ 0 => "Pediatrics" 1 => "Respiratory physiotherapy" 2 => "Pulmonary atelectasis" 3 => "Ultrasound" 4 => "Mechanical ventilation" ] ] ] ] "tieneResumen" => true "highlights" => array:2 [ "titulo" => "Highlights" "resumen" => "<ul class="elsevierStyleList" id="celist0001"><li class="elsevierStyleListItem" id="celistitem0001"><ul class="elsevierStyleList" id="celist0002"><li class="elsevierStyleListItem" id="celistitem0002">•Children are at higher risk of developing atelectasis.</li><li class="elsevierStyleListItem" id="celistitem0003">•Imaging studies have increased specificity in the diagnosis of atelectasis.</li><li class="elsevierStyleListItem" id="celistitem0004">•The use of an ultrasound score can quantify pulmonary aeration.</li></ul></li></ul>" ] "resumen" => array:1 [ "en" => array:2 [ "titulo" => "Abstract" "resumen" => "Children are at higher risk of atelectasis due to their anatomical and physiological particularities. Several physiotherapy techniques are used to treat atelectasis, but only four studies cite methods in pediatric patients undergoing Invasive Mechanical Ventilation (IMV). The objective of this study was to evaluate the Structured Respiratory Physiotherapy Protocol (SRPP) for airway clearance and lung reexpansion for infants on IMV with atelectasis. This is a prospective study including 30 infants (mean ± standard deviation age 8.9 ± 8.0 months; weight 7.5 ± 3.0 kg; BMI 15.8 ± 1.6 kg/cm2 and IMV duration 7.7 ± 4.3 days). The sample was randomized into a Control Group (CG), which received routine physiotherapy, and an Intervention Group (IG), submitted to SRPP (postural drainage, mechanical thoracic vibration, manual hyperinflation, stretching of the accessory respiratory muscles, and functional positioning). Both groups were evaluated before and after physiotherapy for respiratory effort using the Wood Downes Score (WD) and pulmonary aeration using lung ultrasonography (Lung Ultrasound Score ‒ LUS). The outcome of the intervention was evaluated by the magnitude of the effect by the Hedges' g test [(small (0.2 < Hedges' g < 0.5), moderate (0.5 < Hedges' g < 0.8) and large (Hedges' g > 0.8) effects]. There were large within-group effects on the reduction of WD in the CG after intervention in both the CG (Hedges' g = -1.53) and IG (Hedges' g = -2.2). There was a moderate effect on LUS reduction in the CG (Hedges' g = -0.64) and a large effect on IG (Hedges' g = -1.88). This study has shown that the SRPP appears to be safe and may be effective in improving airway clearance and lung reexpansion in children on IMV with atelectasis." ] ] "multimedia" => array:9 [ 0 => array:8 [ "identificador" => "fig0001" "etiqueta" => "Fig. 1" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr1.jpeg" "Alto" => 2863 "Ancho" => 2167 "Tamanyo" => 179710 ] ] "detalles" => array:1 [ 0 => array:3 [ "identificador" => "alt0005" "detalle" => "Fig " "rol" => "short" ] ] "descripcion" => array:1 [ "en" => "Description of patient selection. Note: ICU, Intensive Care Unit; IMV, Invasive Mechanical Ventilation." ] ] 1 => array:8 [ "identificador" => "fig0002" "etiqueta" => "Fig. 2" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr2.jpeg" "Alto" => 747 "Ancho" => 2833 "Tamanyo" => 358378 ] ] "detalles" => array:1 [ 0 => array:3 [ "identificador" => "alt0006" "detalle" => "Fig " "rol" => "short" ] ] "descripcion" => array:1 [ "en" => "Positioning for stretching the respiratory muscles: (A) Upper trapezius; (B) Sternocleidomastoid; (C) Pectoralis major and (D) Intercostals. Source: The author (2023)." ] ] 2 => array:8 [ "identificador" => "fig0003" "etiqueta" => "Fig. 3" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr3.jpeg" "Alto" => 2967 "Ancho" => 2833 "Tamanyo" => 204203 ] ] "detalles" => array:1 [ 0 => array:3 [ "identificador" => "alt0007" "detalle" => "Fig " "rol" => "short" ] ] "descripcion" => array:1 [ "en" => "Sample selection flowchart." ] ] 3 => array:8 [ "identificador" => "fig0004" "etiqueta" => "Fig. 4" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr4.jpeg" "Alto" => 1349 "Ancho" => 3167 "Tamanyo" => 142183 ] ] "detalles" => array:1 [ 0 => array:3 [ "identificador" => "alt0008" "detalle" => "Fig " "rol" => "short" ] ] "descripcion" => array:1 [ "en" => "Magnitude of the effect (effect size) of the intervention proposed in the study (GI) on LUS (y axis), compared to the effect of routine physiotherapy (CG), shown by the differences between the medians (green bars) and the values “g” for Hedges." ] ] 4 => array:8 [ "identificador" => "fig0005" "etiqueta" => "Fig. 5" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr5.jpeg" "Alto" => 1267 "Ancho" => 3167 "Tamanyo" => 146115 ] ] "detalles" => array:1 [ 0 => array:3 [ "identificador" => "alt0009" "detalle" => "Fig " "rol" => "short" ] ] "descripcion" => array:1 [ "en" => "Magnitude of the effect (effect size) of the intervention proposed in the study (GI) on the Wood-Downes score (y-axis), compared to the effect of routine physiotherapy (CG), shown by the differences between the medians (green bars) and by Hedges’ “g” values." ] ] 5 => array:8 [ "identificador" => "tbl0001" "etiqueta" => "Table 1" "tipo" => "MULTIMEDIATABLA" "mostrarFloat" => true "mostrarDisplay" => false "detalles" => array:1 [ 0 => array:3 [ "identificador" => "alt0001" "detalle" => "Table " "rol" => "short" ] ] "tabla" => array:2 [ "leyenda" => "NOTE: a Median (IIQ 25%‒75%); b Mean ± Standard Deviation; c Variables with multiple subvariables did not allow generating statistical significance due to the number of cases.p*, p-values by the Wilcoxon/Mann-Whitney test or Fisher's exact test, when applicable; N, Absolute number; Kg, Kilogram; cm, Centimeters; BMI, Body Mass Index; PIM2, Pediatric Index of Mortality 2; IMV, Invasive Mechanical Ventilation; ICU, Intensive Care Unit, pH, Hydrogen Potential; PaO2, Partial Pressure of Oxygen; PaCO2, Partial Pressure of Carbon Dioxide; BE, Base Excess; SaO2, Arterial Oxygen Saturation; PaO2/FiO2, Ratio of Partial Pressure of Oxygen to the fraction of inspired oxygen; Hb, Hemoglobin; Ht, Hematocrit; CRP, C-Reactive Protein; RSV, Respiratory Syncytial Virus." "tablatextoimagen" => array:1 [ 0 => array:2 [ "tabla" => array:1 [ 0 => """ <table border="0" frame="\n \t\t\t\t\tvoid\n \t\t\t\t" class=""><thead title="thead"><tr title="table-row"><a name="en0001"></a><th class="td" title="\n \t\t\t\t\ttable-head\n \t\t\t\t " align="" valign="top" scope="col">Variables \t\t\t\t\t\t\n \t\t\t\t\t\t</th><a name="en0002"></a><th class="td-with-role" title="\n \t\t\t\t\ttable-head\n \t\t\t\t ; entry_with_role_colgroup " colspan="2" align="left" valign="top" scope="col">Group Control</th><a name="en0003"></a><th class="td-with-role" title="\n \t\t\t\t\ttable-head\n \t\t\t\t ; entry_with_role_colgroup " colspan="2" align="left" valign="top" scope="col">Group Intervention</th><a name="en0004"></a><th class="td" title="\n \t\t\t\t\ttable-head\n \t\t\t\t " align="" valign="top" scope="col">p* \t\t\t\t\t\t\n \t\t\t\t\t\t</th></tr><tr title="table-row"><a name="en0005"></a><th class="td" title="\n \t\t\t\t\ttable-head\n \t\t\t\t " align="" valign="top" scope="col" style="border-bottom: 2px solid black">N \t\t\t\t\t\t\n \t\t\t\t\t\t</th><a name="en0006"></a><th class="td-with-role" title="\n \t\t\t\t\ttable-head\n \t\t\t\t ; entry_with_role_colgroup " colspan="2" align="left" valign="top" scope="col" style="border-bottom: 2px solid black">15</th><a name="en0007"></a><th class="td-with-role" title="\n \t\t\t\t\ttable-head\n \t\t\t\t ; entry_with_role_colgroup " colspan="2" align="left" valign="top" scope="col" style="border-bottom: 2px solid black">15</th><a name="en0008"></a><th class="td" title="\n \t\t\t\t\ttable-head\n \t\t\t\t " align="" valign="top" scope="col" style="border-bottom: 2px solid black">‒ \t\t\t\t\t\t\n \t\t\t\t\t\t</th></tr></thead><tbody title="tbody"><tr title="table-row"><a name="en0009"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">Female gender, n (%) \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0010"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">6 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0011"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">40 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0012"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">4 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0013"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">26.7 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0014"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">0.6 \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><a name="en0015"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">Age (months)a \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0016"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">7 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0017"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">2.0‒17.0 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0018"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">4 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0019"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">2.0‒13.5 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0020"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">0.7 \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><a name="en0021"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">Diagnostics \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0022"></a><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_colgroup " colspan="5" align="left" valign="top"></td></tr><tr title="table-row"><a name="en0023"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">Viral bronchiolitis \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0024"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">11 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0025"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">73.3 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0026"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">11 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0027"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">73.3 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0028"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">c \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><a name="en0029"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">Pneumonia \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0030"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">‒ \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0031"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">‒ \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0032"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">1 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0033"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">6.7 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0034"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">c \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><a name="en0035"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">Nephrotic syndrome \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0036"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">‒ \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0037"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">‒ \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0038"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">1 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0039"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">6.7 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0040"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">c \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><a name="en0041"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">Septic shock \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0042"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">3 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0043"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">20 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0044"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">2 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0045"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">13.3 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0046"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">c \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><a name="en0047"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">Wheezing crisis \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0048"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">1 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0049"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">6.7 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0050"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">‒ \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0051"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">‒ \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0052"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">c \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><a name="en0053"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">Weight (Kg)b \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0054"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">7.7 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0055"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">3.2 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0056"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">7.4 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0057"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">2.9 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0058"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">0.4 \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><a name="en0059"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">Height (cm)b \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0060"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">68.3 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0061"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">12 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0062"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">67 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0063"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">12.6 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0064"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">0.7 \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><a name="en0065"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">BMI (Kg/cm2)b \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0066"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">15.5 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0067"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">1.7 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0068"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">16.2 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0069"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">1.6 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0070"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">0.4 \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><a name="en0071"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">PIM2b \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0072"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">5 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0073"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">7.5 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0074"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">2.1 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0075"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">1.3 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0076"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">0.6 \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><a name="en0077"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">Duration of IMV (days)a \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0078"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">7 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0079"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">5.5‒8.5 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0080"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">6 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0081"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">4.5‒8.5 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0082"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">0.5 \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><a name="en0083"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">ICU length of stay (days)a \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0084"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">15 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0085"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">11.0‒16.0 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0086"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">12 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0087"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">9.5‒18.5 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0088"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">0.4 \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><a name="en0089"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">Hospital length of stay (days)a \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0090"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">19 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0091"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">17.0‒24.0 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0092"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">21 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0093"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">12.5‒24.5 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0094"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">0.6 \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><a name="en0095"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">pHa \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0096"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">7.4 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0097"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">0.1 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0098"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">7.4 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0099"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">0.1 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0100"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">0.3 \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><a name="en0101"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">PaO2a \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0102"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">91.5 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0103"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">40.3 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0104"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">108.7 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0105"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">37.8 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0106"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">0.3 \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><a name="en0107"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">PaCO2a \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0108"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">46 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0109"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">10.7 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0110"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">46.3 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0111"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">14.1 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0112"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">0.8 \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><a name="en0113"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">HCO3a \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0114"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">29 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0115"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">7 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0116"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">26.7 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0117"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">5.2 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0118"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">0.2 \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><a name="en0119"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">BEa \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0120"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">3.8 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0121"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">7.3 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0122"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">1.1 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0123"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">4.9 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0124"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">0.1 \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><a name="en0125"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">SaO2a \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0126"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">93.1 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0127"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">8.3 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0128"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">96.3 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0129"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">4.5 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0130"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">0.5 \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><a name="en0131"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">PaO2/FiO2a \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0132"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">256.9 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0133"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">171.4 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0134"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">299.7 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0135"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">106.6 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0136"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">0.3 \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><a name="en0137"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">Hba \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0138"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">10 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0139"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">1.4 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0140"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">9.7 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0141"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">1.5 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0142"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">0.3 \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><a name="en0143"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">Hta \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0144"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">30.2 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0145"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">4.2 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0146"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">27.6 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0147"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">4.5 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0148"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">0.07 \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><a name="en0149"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">Plateletsa \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0150"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">326533.3 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0151"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">143116.8 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0152"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">316000 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0153"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">134982 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0154"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">0.6 \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><a name="en0155"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">Lactatea \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0156"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">1.8 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0157"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">1.6 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0158"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">1.6 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0159"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">1 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0160"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">0.9 \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><a name="en0161"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">CRPa \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0162"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">3.5 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0163"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">2.9 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0164"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">5.7 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0165"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">5.5 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0166"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">0.4 \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><a name="en0167"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">Viral panel \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0168"></a><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_colgroup " colspan="5" align="left" valign="top"></td></tr><tr title="table-row"><a name="en0169"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">RSV \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0170"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">9 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0171"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">81.8 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0172"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">8 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0173"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">72.7 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0174"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">c \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><a name="en0175"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">Bocavirus \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0176"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">2 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0177"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">18.2 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0178"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">‒ \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0179"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">‒ \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0180"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">c \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><a name="en0181"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">Parainfluenza I e II \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0182"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">‒ \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0183"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">‒ \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0184"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">1 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0185"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">9.1 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0186"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">c \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><a name="en0187"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">Metapnemovirus \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0188"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">‒ \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0189"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">‒ \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0190"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">1 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0191"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">9.1 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0192"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">c \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><a name="en0193"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">Seasonal coronavirus \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0194"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">‒ \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0195"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">‒ \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0196"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">1 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0197"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">9.1 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0198"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">c \t\t\t\t\t\t\n \t\t\t\t</td></tr></tbody></table> """ ] "imagenFichero" => array:1 [ 0 => "xTab3692114.png" ] ] ] ] "descripcion" => array:1 [ "en" => "Epidemiological characteristics, clinical variables and laboratory tests of the sample according to groups and results of statistical tests." ] ] 6 => array:8 [ "identificador" => "tbl0002" "etiqueta" => "Table 2" "tipo" => "MULTIMEDIATABLA" "mostrarFloat" => true "mostrarDisplay" => false "detalles" => array:1 [ 0 => array:3 [ "identificador" => "alt0002" "detalle" => "Table " "rol" => "short" ] ] "tabla" => array:2 [ "leyenda" => "Note: a Mean and standard deviation; b Variables with multiple subvariables did not allow generating statistical significance due to the number of cases.p*, p-values by the Wilcoxon/Mann-Whitney test.N, Absolute Number; IMV, Invasive Mechanical Ventilation; PCV, Pressure Controlled Ventilation; PSV, Pressure Support Ventilation; PRVC, Pressure-Regulated and Volume-Controlled Ventilation; SIMV, Synchronized Intermittent Mandatory Ventilation; cm H2O, Centimeters of Water; PIP, Peak Inspiratory Pressure; PEEP, Positive End-Expiratory Pressure; RR, Respiratory Rate; ipm, Incursions per minute; IT, Inspiratory Time; s, seconds; FiO2, Fraction of Inspired Oxygen; MAP, Mean Airway Pressure; TV, Total Volume; mL, Milliliter; VT, Tidal Volume; mL/Kg, Milliliter per kilo; VAP, Ventilator-Associated Pneumonia; Radiological score, Radiological Atelectasis Scoring System; RUL, Right Upper Lobe; RML, Right Middle Lobe; LLL, Left Lower Lobe." "tablatextoimagen" => array:1 [ 0 => array:2 [ "tabla" => array:1 [ 0 => """ <table border="0" frame="\n \t\t\t\t\tvoid\n \t\t\t\t" class=""><thead title="thead"><tr title="table-row"><a name="en0199"></a><th class="td" title="\n \t\t\t\t\ttable-head\n \t\t\t\t " align="" valign="top" scope="col" style="border-bottom: 2px solid black">Variables \t\t\t\t\t\t\n \t\t\t\t\t\t</th><a name="en0200"></a><th class="td-with-role" title="\n \t\t\t\t\ttable-head\n \t\t\t\t ; entry_with_role_colgroup " colspan="2" align="left" valign="top" scope="col" style="border-bottom: 2px solid black">Control group</th><a name="en0201"></a><th class="td-with-role" title="\n \t\t\t\t\ttable-head\n \t\t\t\t ; entry_with_role_colgroup " colspan="2" align="left" valign="top" scope="col" style="border-bottom: 2px solid black">Intervention group</th><a name="en0202"></a><th class="td" title="\n \t\t\t\t\ttable-head\n \t\t\t\t " align="" valign="top" scope="col" style="border-bottom: 2px solid black">p* \t\t\t\t\t\t\n \t\t\t\t\t\t</th></tr></thead><tbody title="tbody"><tr title="table-row"><a name="en0203"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">IMV mode, n (%) \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0204"></a><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_colgroup " colspan="5" align="left" valign="top"></td></tr><tr title="table-row"><a name="en0205"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">PCV (cm H2O) \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0206"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">11.0 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0207"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">73.3 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0208"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">10.0 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0209"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">66.6 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0210"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">b \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><a name="en0211"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">PSV (cm H2O) \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0212"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">1.0 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0213"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">6.7 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0214"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">1.0 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0215"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">6.7 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0216"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">b \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><a name="en0217"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">PRVC (cm H2O) \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0218"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">‒ \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0219"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">‒ \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0220"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">1.0 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0221"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">6.7 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0222"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">b \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><a name="en0223"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">SIMV (cm H2O) \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0224"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">3.0 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0225"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">20.0 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0226"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">3.0 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0227"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">20.0 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0228"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">b \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><a name="en0229"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">Ventilatory parametersa \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0230"></a><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_colgroup " colspan="5" align="left" valign="top"></td></tr><tr title="table-row"><a name="en0231"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">PIP (cm H2O) \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0232"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">21.7 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0233"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">3.0 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0234"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">22.1 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0235"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">3.6 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0236"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">0.8 \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><a name="en0237"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">PEEP (cm H2O) \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0238"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">7.0 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0239"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">1.0 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0240"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">6.8 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0241"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">0.6 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0242"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">0.7 \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><a name="en0243"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">RR (ipm) \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0244"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">27.3 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0245"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">5.3 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0246"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">25.8 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0247"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">3.8 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0248"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">0.7 \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><a name="en0249"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">IT (s) \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0250"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">0.6 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0251"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">0.1 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0252"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">0.6 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0253"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">0.1 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0254"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">0.7 \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><a name="en0255"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">FiO2 (%) \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0256"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">44.0 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0257"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">18.4 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0258"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">37.8 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0259"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">12.2 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0260"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">0.6 \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><a name="en0261"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">MAP (cm H2O) \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0262"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">11.5 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0263"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">2.0 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0264"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">13.0 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0265"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">1.9 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0266"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">0.1 \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><a name="en0267"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">TV (mL) \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0268"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">65.8 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0269"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">36.8 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0270"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">61.3 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0271"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">38.9 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0272"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">0.3 \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><a name="en0273"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">VT (mL/Kg) \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0274"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">6.0 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0275"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">3.0 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0276"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">8.0 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0277"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">2.5 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0278"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">0.9 \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><a name="en0279"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">Intratracheal cuff, n (%) \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0280"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">6.0 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0281"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">40.0 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0282"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">6.0 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0283"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">40.0 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0284"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">b \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><a name="en0285"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">VAP, n (%) \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0286"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">2.0 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0287"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">13.3 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0288"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">1.0 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0289"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">6.7 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0290"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">b \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><a name="en0291"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">Radiological scorea \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0292"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">2.7 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0293"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">0.9 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0294"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">3.1 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0295"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">0.9 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0296"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">0.3 \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><a name="en0297"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">Location of atelectasisa \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0298"></a><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_colgroup " colspan="5" align="left" valign="top"></td></tr><tr title="table-row"><a name="en0299"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">RUL \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0300"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">9.0 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0301"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">60.0 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0302"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">11.0 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0303"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">73.3 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0304"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">b \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><a name="en0305"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">RML \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0306"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">4.0 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0307"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">26.7 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0308"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">4.0 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0309"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">26.7 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0310"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">b \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><a name="en0311"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">LLL \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0312"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">2.0 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0313"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">13.3 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0314"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">‒ \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0315"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">‒ \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0316"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">b \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><a name="en0317"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">Aspirationsa \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0318"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">1.8 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0319"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">0.8 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0320"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">2.1 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0321"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">0.8 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0322"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">0.4 \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><a name="en0323"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">Quality, n (%) \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0324"></a><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_colgroup " colspan="5" align="left" valign="top"></td></tr><tr title="table-row"><a name="en0325"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">Moderate \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0326"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">14.0 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0327"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">93.3 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0328"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">15.0 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0329"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">100.0 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0330"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">b \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><a name="en0331"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">Thick \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0332"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">1.0 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0333"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">6.7 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0334"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">‒ \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0335"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">‒ \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0336"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">b \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><a name="en0337"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">Colour, n (%) \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0338"></a><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_colgroup " colspan="5" align="left" valign="top"></td></tr><tr title="table-row"><a name="en0339"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">Clear \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0340"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">10.0 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0341"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">66.7 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0342"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">10.0 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0343"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">66.7 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0344"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">b \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><a name="en0345"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">Yellowish \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0346"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">5.0 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0347"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">33.3 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0348"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">5.0 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0349"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">33.3 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0350"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">b \t\t\t\t\t\t\n \t\t\t\t</td></tr></tbody></table> """ ] "imagenFichero" => array:1 [ 0 => "xTab3692113.png" ] ] ] ] "descripcion" => array:1 [ "en" => "Description of modes, ventilation parameters, incidence of Ventilator-Associated Pneumonia (VAP), Radiological Atelectasis Scoring System score, location of atelectasis and characteristics of tracheal secretion according to groups and results of statistical tests." ] ] 7 => array:8 [ "identificador" => "tbl0003" "etiqueta" => "Table 3" "tipo" => "MULTIMEDIATABLA" "mostrarFloat" => true "mostrarDisplay" => false "detalles" => array:1 [ 0 => array:3 [ "identificador" => "alt0003" "detalle" => "Table " "rol" => "short" ] ] "tabla" => array:2 [ "leyenda" => "Note: P25, 25th percentile; P75, 75th percentile.p*, p-values by the Wilcoxon/Mann-Whitney test.LUS, Lung Ultrasound Score; WD, Wood-Downes; CG, Control Group; IG, Intervention Group; Before, Before respiratory physiotherapy; After, After respiratory physiotherapy." "tablatextoimagen" => array:1 [ 0 => array:2 [ "tabla" => array:1 [ 0 => """ <table border="0" frame="\n \t\t\t\t\tvoid\n \t\t\t\t" class=""><thead title="thead"><tr title="table-row"><a name="en0351"></a><th class="td" title="\n \t\t\t\t\ttable-head\n \t\t\t\t " align="" valign="top" scope="col" style="border-bottom: 2px solid black">Score \t\t\t\t\t\t\n \t\t\t\t\t\t</th><a name="en0352"></a><th class="td" title="\n \t\t\t\t\ttable-head\n \t\t\t\t " align="" valign="top" scope="col" style="border-bottom: 2px solid black">Median \t\t\t\t\t\t\n \t\t\t\t\t\t</th><a name="en0353"></a><th class="td" title="\n \t\t\t\t\ttable-head\n \t\t\t\t " align="" valign="top" scope="col" style="border-bottom: 2px solid black">P 25 \t\t\t\t\t\t\n \t\t\t\t\t\t</th><a name="en0354"></a><th class="td" title="\n \t\t\t\t\ttable-head\n \t\t\t\t " align="" valign="top" scope="col" style="border-bottom: 2px solid black">P 75 \t\t\t\t\t\t\n \t\t\t\t\t\t</th><a name="en0355"></a><th class="td" title="\n \t\t\t\t\ttable-head\n \t\t\t\t " align="" valign="top" scope="col" style="border-bottom: 2px solid black">p* \t\t\t\t\t\t\n \t\t\t\t\t\t</th></tr></thead><tbody title="tbody"><tr title="table-row"><a name="en0356"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">LUS CG before \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0357"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">2.0 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0358"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">1.0 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0359"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">3.0 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0360"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">0.01 \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><a name="en0361"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">LUS CG after \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0362"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">1.0 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0363"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">1.0 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0364"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">2.5 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0365"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top"> \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><a name="en0366"></a><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_colgroup " colspan="5" align="left" valign="top"></td></tr><tr title="table-row"><a name="en0367"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">LUS IG before \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0368"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">3.0 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0369"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">2.0 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0370"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">3.0 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0371"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top"><0.001 \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><a name="en0372"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">LUS IG after \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0373"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">1.0 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0374"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">0.5 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0375"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">2.0 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0376"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top"> \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><a name="en0377"></a><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_colgroup " colspan="5" align="left" valign="top"></td></tr><tr title="table-row"><a name="en0378"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">WD CG before \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0379"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">4.0 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0380"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">3.5 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0381"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">5.0 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0382"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top"><0.001 \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><a name="en0383"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">WD CG after \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0384"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">3.0 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0385"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">2.0 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0386"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">3.0 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0387"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top"> \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><a name="en0388"></a><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; entry_with_role_colgroup " colspan="5" align="left" valign="top"></td></tr><tr title="table-row"><a name="en0389"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">WD IG before \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0390"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">4.0 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0391"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">3.0 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0392"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">5.0 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0393"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top"><0.001 \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><a name="en0394"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">WD IG after \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0395"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">2.0 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0396"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">1.0 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0397"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">2.5 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0398"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top"> \t\t\t\t\t\t\n \t\t\t\t</td></tr></tbody></table> """ ] "imagenFichero" => array:1 [ 0 => "xTab3692111.png" ] ] ] ] "descripcion" => array:1 [ "en" => "Description of LUS and Wood-Downes Score comparing groups, moments and results of statistical tests." ] ] 8 => array:8 [ "identificador" => "tbl0004" "etiqueta" => "Table 4" "tipo" => "MULTIMEDIATABLA" "mostrarFloat" => true "mostrarDisplay" => false "detalles" => array:1 [ 0 => array:3 [ "identificador" => "alt0004" "detalle" => "Table " "rol" => "short" ] ] "tabla" => array:2 [ "leyenda" => "Note: Data are in means and standard deviations.p*, p-values according to the non-parametric Friedman test, with post-hoc analysis using the paired Wilcoxon test (signed rank), with Bonferroni correction.Before, Before respiratory physiotherapy; HR, Heart Rate; min, Minutes; RR, Respiratory Rate; Temp, Body Temperature in degrees Celsius; degrees Celsius; SPO2, Peripheral Oxygen Saturation; SBP, Systolic Blood Pressure; DBP, Diastolic Blood Pressure; ABP, Average Arterial Pressure." "tablatextoimagen" => array:1 [ 0 => array:2 [ "tabla" => array:1 [ 0 => """ <table border="0" frame="\n \t\t\t\t\tvoid\n \t\t\t\t" class=""><thead title="thead"><tr title="table-row"><a name="en0399"></a><th class="td" title="\n \t\t\t\t\ttable-head\n \t\t\t\t " align="" valign="top" scope="col" style="border-bottom: 2px solid black">Variables \t\t\t\t\t\t\n \t\t\t\t\t\t</th><a name="en0400"></a><th class="td-with-role" title="\n \t\t\t\t\ttable-head\n \t\t\t\t ; entry_with_role_colgroup " colspan="2" align="left" valign="top" scope="col" style="border-bottom: 2px solid black">Group control</th><a name="en0401"></a><th class="td-with-role" title="\n \t\t\t\t\ttable-head\n \t\t\t\t ; entry_with_role_colgroup " colspan="2" align="left" valign="top" scope="col" style="border-bottom: 2px solid black">Group intervention</th><a name="en0402"></a><th class="td" title="\n \t\t\t\t\ttable-head\n \t\t\t\t " align="" valign="top" scope="col" style="border-bottom: 2px solid black">p* \t\t\t\t\t\t\n \t\t\t\t\t\t</th></tr></thead><tbody title="tbody"><tr title="table-row"><a name="en0403"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">HR before (bpm) \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0404"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">139.9 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0405"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">26.7 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0406"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">142.7 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0407"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">23.3 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0408"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">0.9 \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><a name="en0409"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">HR 10 min (bpm) \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0410"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">140.9 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0411"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">22 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0412"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">140.5 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0413"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">20.3 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0414"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">0.8 \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><a name="en0415"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">HR 30 min (bpm) \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0416"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">137.1 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0417"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">23.9 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0418"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">135.9 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0419"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">19.7 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0420"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">0.8 \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><a name="en0421"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">RR before (ipm) \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0422"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">38.3 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0423"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">11.1 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0424"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">37.4 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0425"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">10.2 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0426"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">0.8 \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><a name="en0427"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">RR 10 min (ipm) \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0428"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">36.8 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0429"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">8.5 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0430"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">34.7 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0431"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">7.6 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0432"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">0.7 \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><a name="en0433"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">RR 30 min (ipm) \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0434"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">32.5 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0435"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">7.1 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0436"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">32.3 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0437"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">5.4 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0438"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">0.9 \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><a name="en0439"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">Temp. before (°C) \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0440"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">36.7 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0441"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">0.5 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0442"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">36.6 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0443"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">0.5 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0444"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">0.7 \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><a name="en0445"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">Temp. 10 min (°C) \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0446"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">36.6 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0447"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">0.4 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0448"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">36.6 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0449"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">0.5 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0450"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">0.7 \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><a name="en0451"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">Temp. 30 min (°C) \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0452"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">36.7 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0453"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">0.4 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0454"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">36.6 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0455"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">0.5 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0456"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">0.6 \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><a name="en0457"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">SPO2 before (%) \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0458"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">95.5 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0459"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">3.4 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0460"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">96.5 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0461"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">4.1 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0462"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">0.4 \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><a name="en0463"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">SPO2 10 min (%) \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0464"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">98.2 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0465"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">2.5 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0466"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">98.2 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0467"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">2 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0468"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">0.8 \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><a name="en0469"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">SPO2 30 min (%) \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0470"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">97.9 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0471"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">2.4 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0472"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">98.5 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0473"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">2.2 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0474"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">0.5 \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><a name="en0475"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">SBP before (mmHg) \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0476"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">98.1 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0477"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">17.2 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0478"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">104.3 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0479"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">13.1 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0480"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">0.3 \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><a name="en0481"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">SBP 10 min (mmHg) \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0482"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">104.5 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0483"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">17.3 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0484"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">104.1 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0485"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">15.4 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0486"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">0.8 \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><a name="en0487"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">SBP 30 min (mmHg) \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0488"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">99.4 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0489"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">20.5 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0490"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">98.5 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0491"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">16.6 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0492"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">0.6 \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><a name="en0493"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">DBP before (mmHg) \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0494"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">57.1 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0495"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">14.3 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0496"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">59.5 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0497"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">9.6 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0498"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">0.4 \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><a name="en0499"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">DBP 10 min (mmHg) \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0500"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">57.6 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0501"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">12.5 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0502"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">53.7 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0503"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">10.2 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0504"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">0.7 \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><a name="en0505"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">DBP 30 min (mmHg) \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0506"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">55.4 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0507"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">13.5 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0508"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">52.9 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0509"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">11.5 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0510"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">0.7 \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><a name="en0511"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">ABP before (mmHg) \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0512"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">71.5 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0513"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">14.3 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0514"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">75.5 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0515"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">10.1 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0516"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">0.3 \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><a name="en0517"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">ABP 10 min (mmHg) \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0518"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">74.4 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0519"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">13 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0520"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">71.6 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0521"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">12.6 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0522"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">0.6 \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><a name="en0523"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">ABP 30 min (mmHg) \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0524"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">71.2 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0525"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">13.9 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0526"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">68 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0527"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">12.2 \t\t\t\t\t\t\n \t\t\t\t</td><a name="en0528"></a><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="" valign="top">0.3 \t\t\t\t\t\t\n \t\t\t\t</td></tr></tbody></table> """ ] "imagenFichero" => array:1 [ 0 => "xTab3692112.png" ] ] ] ] "descripcion" => array:1 [ "en" => "Description of vital signs according to groups and moments and results of statistical tests." ] ] ] "bibliografia" => array:2 [ "titulo" => "References" "seccion" => array:1 [ 0 => array:2 [ "identificador" => "cebibsec1" "bibliografiaReferencia" => array:40 [ 0 => array:3 [ "identificador" => "bib0001" "etiqueta" => "1" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Radiologia de tórax para pediatras, clínica de tórax para radiologistas" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "JPB Lotufo" 1 => "HM. Lederman" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:3 [ "tituloSerie" => "São Paulo" "fecha" => "2009" "paginaInicial" => "22" ] ] ] ] ] ] 1 => array:3 [ "identificador" => "bib0002" "etiqueta" => "2" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Atelectasia pulmonar em recém-nascidos com doenças clinicamente tratáveis submetidos à ventilação mecânica: aspectos clínicos e radiológicos" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "MC Dominguez" 1 => "BR. Alvares" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Radiol Bras" "fecha" => "2018" "volumen" => "51" "numero" => "1" "paginaInicial" => "20" "paginaFinal" => "25" ] ] ] ] ] ] 2 => array:3 [ "identificador" => "bib0003" "etiqueta" => "3" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Atelectasis: mechanisms, diagnosis and management" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "DG Peroni" 1 => "AL. Boner" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Paediatric Respiratory Reviews" "fecha" => "2000" "volumen" => "1" "numero" => "3" "paginaInicial" => "274" "paginaFinal" => "278" ] ] ] ] ] ] 3 => array:3 [ "identificador" => "bib0004" "etiqueta" => "4" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Complications during mechanical ventilation ‒ A pediatric intensive care perspective" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ 0 => "S Sood" 1 => "HA Ganatra" 2 => "F Perez Marques" 3 => "TR Langner" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:3 [ "tituloSerie" => "Front Med (Lausanne)" "fecha" => "2023" "volumen" => "10" ] ] ] ] ] ] 4 => array:3 [ "identificador" => "bib0005" "etiqueta" => "5" "referencia" => array:1 [ 0 => array:1 [ "referenciaCompleta" => "GHO|By category | Number of deaths by region ‒ Acute lower respiratory infections [Internet]. WHO. [Acesso em 08 Set 2023]. Disponível em: <a target="_blank" href="https://apps.who.int/gho/data/view.main.CM1002015REG6-CH9?lang=en">https://apps.who.int/gho/data/view.main.CM1002015REG6-CH9?lang=en</a>." ] ] ] 5 => array:3 [ "identificador" => "bib0006" "etiqueta" => "6" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "What is the role of the physiotherapist in paediatric intensive care units? A systematic review of the evidence for respiratory and rehabilitation interventions for mechanically ventilated patients" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "E Hawkins" 1 => "A. Jones" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Physiotherapy" "fecha" => "2015" "volumen" => "101" "numero" => "4" "paginaInicial" => "303" "paginaFinal" => "309" ] ] ] ] ] ] 6 => array:3 [ "identificador" => "bib0007" "etiqueta" => "7" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Bronchoscopy for atelectasis in the ICU: a case report and review of the literature" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "ME Kreider" 1 => "DA. Lipson" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Chest" "fecha" => "2003" "volumen" => "124" "numero" => "1" "paginaInicial" => "344" "paginaFinal" => "350" ] ] ] ] ] ] 7 => array:3 [ "identificador" => "bib0008" "etiqueta" => "8" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Commentary: Treatment of atelectasis: where is the evidence?" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "MB Schindler" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Crit Care" "fecha" => "2005" "volumen" => "9" "numero" => "4" "paginaInicial" => "341" ] ] ] ] ] ] 8 => array:3 [ "identificador" => "bib0009" "etiqueta" => "9" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Atelectasias pulmonares em pediatria: mecanismos, métodos diagnósticos, prevenção e tratamento" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "C Johnston" 1 => "P Camassuti" 2 => "WB Carvalho" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:4 [ "tituloSerie" => "Piva JP, Carvalho WB. PROTIPED" "fecha" => "2023" "paginaInicial" => "11" "paginaFinal" => "62" ] ] ] ] ] ] 9 => array:3 [ "identificador" => "bib0010" "etiqueta" => "10" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Lobar atelectasis: diagnostics pitfalls on chest radiography" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ 0 => "K Ashizawa" 1 => "K Hayashi" 2 => "N Aso" 3 => "K Minami" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Br J Radiol" "fecha" => "2001" "volumen" => "74" "numero" => "877" "paginaInicial" => "89" "paginaFinal" => "97" ] ] ] ] ] ] 10 => array:3 [ "identificador" => "bib0011" "etiqueta" => "11" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Variability and accuracy in interpretation of consolidation on chest radiography for diagnosing pneumonia in children under 5 years of age" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "GJ Williams" 1 => "P Macaskill" 2 => "M Kerr" 3 => "DA Fitzgerald" 4 => "D Isaacs" 5 => "M Codarini" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Pediatr Pulmonol" "fecha" => "2013" "volumen" => "48" "numero" => "12" "paginaInicial" => "1195" "paginaFinal" => "1200" ] ] ] ] ] ] 11 => array:3 [ "identificador" => "bib0012" "etiqueta" => "12" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Fifteen-minute consultation: Using point of care ultrasound to assess children with respiratory failure" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "HL Ord" 1 => "MJ. Griksaitis" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Arch Dis Child Educ Pract Ed" "fecha" => "2018" "volumen" => "104" "numero" => "1" "paginaInicial" => "2" "paginaFinal" => "10" ] ] ] ] ] ] 12 => array:3 [ "identificador" => "bib0013" "etiqueta" => "13" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Right middle lobe atelectasis in children with asthma and prognostic factors" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:5 [ 0 => "O Soyer" 1 => "C Ozen" 2 => "O Cavkaytar" 3 => "C Senyücel" 4 => "Y. Dallar" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Allergol Int" "fecha" => "2016" "volumen" => "65" "numero" => "3" "paginaInicial" => "253" "paginaFinal" => "258" ] ] ] ] ] ] 13 => array:3 [ "identificador" => "bib0014" "etiqueta" => "14" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Bedside management of lung collapse in children on mechanical ventilation: Saline lavage ‒ simulated cough technique proves simple, effective" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "AG Galvis" 1 => "G Reyes" 2 => "WB. Nelson" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Pediatr Pulmonol" "fecha" => "1994" "volumen" => "17" "numero" => "5" "paginaInicial" => "326" "paginaFinal" => "330" ] ] ] ] ] ] 14 => array:3 [ "identificador" => "bib0015" "etiqueta" => "15" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Medical treatment of lung collapse in children" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "N Bilan" 1 => "BA Galehgolab" 2 => "M. Shoaran" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Pak J Biol Sci" "fecha" => "2009" "volumen" => "12" "numero" => "5" "paginaInicial" => "467" "paginaFinal" => "469" ] ] ] ] ] ] 15 => array:3 [ "identificador" => "bib0016" "etiqueta" => "16" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Children with pulmonary atelectasis: clinical outcome and characterization of physical therapy" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "CCD Pozzo" 1 => "PA Seibert" 2 => "DS. Fujisawa" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Acta Sci Health Sci" "fecha" => "2013" "volumen" => "35" "numero" => "2" "paginaInicial" => "169" "paginaFinal" => "173" ] ] ] ] ] ] 16 => array:3 [ "identificador" => "bib40" "etiqueta" => "17" "referencia" => array:1 [ 0 => array:1 [ "referenciaCompleta" => "Herrada AJM, Wien MA, Shein SL, Maher JK, Zee-Cheng JE, Rotta AT. A novel maneuver to treat refractory atelectasis in mechanically ventilated children, J Pediatr Intensive Care, 2020,11(2),159-167." ] ] ] 17 => array:3 [ "identificador" => "bib0017" "etiqueta" => "18" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Lobar collapse demystified: the chest radiograph with CT correlation" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ 0 => "R Mullett" 1 => "A Jain" 2 => "S Kotugodella" 3 => "J. Curtis" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Postgrad Med J" "fecha" => "2012" "volumen" => "88" "numero" => "1040" "paginaInicial" => "335" "paginaFinal" => "347" ] ] ] ] ] ] 18 => array:3 [ "identificador" => "bib0018" "etiqueta" => "19" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "The use of dornase alpha for post-operative pulmonary atelectasis after congenital heart surgery" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:6 [ 0 => "E Ozturk" 1 => "IC Tanidir" 2 => "S Haydin" 3 => "IS Onan" 4 => "E Odemis" 5 => "I. Bakir" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Cardiol Young" "fecha" => "2014" "volumen" => "24" "numero" => "5" "paginaInicial" => "807" "paginaFinal" => "812" ] ] ] ] ] ] 19 => array:3 [ "identificador" => "bib0019" "etiqueta" => "20" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Lung ultrasound for diagnosis of neonatal atelectasis" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "J Liu" 1 => "Y Liu" 2 => "H Wang" 3 => "J Li" 4 => "T Han" 5 => "J Liang" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Zhonghua Er Ke Za Zhi = Chinese J Pedia" "fecha" => "2013" "volumen" => "51" "numero" => "9" "paginaInicial" => "644" "paginaFinal" => "648" ] ] ] ] ] ] 20 => array:3 [ "identificador" => "bib0020" "etiqueta" => "21" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Lung ultrasonography for the diagnosis of neonatal lung disease" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "J. Liu" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "J Matern Fetal Neonatal Med" "fecha" => "2014" "volumen" => "27" "numero" => "8" "paginaInicial" => "856" "paginaFinal" => "861" ] ] ] ] ] ] 21 => array:3 [ "identificador" => "bib0021" "etiqueta" => "22" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "International evidence-based recommendations for point-of-care lung ultrasound" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "G Volpicelli" 1 => "M Elbarbary" 2 => "M Blaivas" 3 => "DA Lichtenstein" 4 => "G Mathis" 5 => "AW Kirkpatrick" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Intensive Care Med" "fecha" => "2012" "volumen" => "38" "numero" => "4" "paginaInicial" => "577" "paginaFinal" => "591" ] ] ] ] ] ] 22 => array:3 [ "identificador" => "bib0022" "etiqueta" => "23" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Aplicaciones clínicas de la ecografía pulmonar" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "AL. Wangüemert Pérez" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Med Clin" "fecha" => "2020" "volumen" => "154" "numero" => "7" "paginaInicial" => "260" "paginaFinal" => "268" ] ] ] ] ] ] 23 => array:3 [ "identificador" => "bib0023" "etiqueta" => "24" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Lung ultrasonography score to evaluate oxygenation and surfactant need in neonates treated with continuous positive airway pressure" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:6 [ 0 => "R Brat" 1 => "N Yousef" 2 => "R Klifa" 3 => "S Reynaud" 4 => "AS Shankar" 5 => "D. De Luca" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:4 [ "tituloSerie" => "JAMA Pediatr" "fecha" => "2015" "volumen" => "169" "numero" => "8" ] ] ] ] ] ] 24 => array:3 [ "identificador" => "bib0024" "etiqueta" => "25" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "A clinical scoring system for the diagnosis of respiratory failure" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "DW. Wood" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Am J Dis Child" "fecha" => "1972" "volumen" => "123" "numero" => "3" "paginaInicial" => "227" ] ] ] ] ] ] 25 => array:3 [ "identificador" => "bib0025" "etiqueta" => "26" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Terapia Intensiva Pediátrica e Neonatal.4a Edição" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "MR Hirschheimer" 1 => "WB Carvalho" 2 => "T. Matsumoto" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Libro" => array:3 [ "fecha" => "2017" "editorial" => "Editora Atheneu" "editorialLocalizacion" => "São Paulo" ] ] ] ] ] ] 26 => array:3 [ "identificador" => "bib0026" "etiqueta" => "27" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Micro- and macrorheology of mucus" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ 0 => "SK Lai" 1 => "YY Wang" 2 => "D Wirtz" 3 => "J Hanes" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Adv Drug Deliv Rev" "fecha" => "2009" "volumen" => "61" "paginaInicial" => "86" "paginaFinal" => "100" ] ] ] ] ] ] 27 => array:3 [ "identificador" => "bib0027" "etiqueta" => "28" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Airway clearance therapy in acute paediatric respiratory illness: a state-of-the-art review" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "BM. Morrow" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "S Afr J Physiother" "fecha" => "2019" "volumen" => "75" "numero" => "1" "paginaInicial" => "1295" ] ] ] ] ] ] 28 => array:3 [ "identificador" => "bib0028" "etiqueta" => "29" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "I Recomendação brasileira de fisioterapia respiratória em unidade de terapia intensiva pediátrica e neonatal" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:6 [ 0 => "C Johnston" 1 => "NM Zanetti" 2 => "T Comaru" 3 => "SNS Ribeiro" 4 => "LB Andrade" 5 => "SLL. Santos" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Rev Bras Terapia Intensiva" "fecha" => "2012" "volumen" => "24" "numero" => "2" "paginaInicial" => "119" "paginaFinal" => "129" ] ] ] ] ] ] 29 => array:3 [ "identificador" => "bib0029" "etiqueta" => "30" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Immediate effects of respiratory muscle stretching on chest wall kinematics and electromyography in COPD patients" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:6 [ 0 => "RB Sá" 1 => "MF Pessoa" 2 => "AGL Cavalcanti" 3 => "SL Campos" 4 => "C Amorim" 5 => "AA. Dornelas" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Respir Physiol Neurobiol" "fecha" => "2017" "volumen" => "242" "paginaInicial" => "1" "paginaFinal" => "7" ] ] ] ] ] ] 30 => array:3 [ "identificador" => "bib0030" "etiqueta" => "31" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Calculating and reporting effect sizes to facilitate cumulative science: a practical primer for t-tests and ANOVAs" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "D. Lakens" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:4 [ "tituloSerie" => "Front Psychol" "fecha" => "2013" "volumen" => "4" "paginaInicial" => "863" ] ] ] ] ] ] 31 => array:3 [ "identificador" => "bib0031" "etiqueta" => "32" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Atelectasis in pediatrics: mechanisms, diagnosis and treatment" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "C Johnston" 1 => "WB. Carvalho" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Rev Assoc Med Bras" "fecha" => "2008" "volumen" => "54" "numero" => "5" "paginaInicial" => "455" "paginaFinal" => "460" ] ] ] ] ] ] 32 => array:3 [ "identificador" => "bib0032" "etiqueta" => "33" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Diseases of the trachea, bronchi, and smaller airways" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "NT. Griscom" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Radiol Clin North Am" "fecha" => "1993" "volumen" => "31" "numero" => "3" "paginaInicial" => "605" "paginaFinal" => "615" ] ] ] ] ] ] 33 => array:3 [ "identificador" => "bib0033" "etiqueta" => "34" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Benefits and harms of normal saline instillation before endotracheal suctioning in mechanically ventilated adult patients in intensive care units: A systematic literature review and meta-analysis" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "SJ Chang" 1 => "E Kim" 2 => "YO Kwon" 3 => "H Im" 4 => "K Park" 5 => "J Kim" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:3 [ "tituloSerie" => "Intensive Crit Care Nurs" "fecha" => "2023" "volumen" => "78" ] ] ] ] ] ] 34 => array:3 [ "identificador" => "bib0034" "etiqueta" => "35" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Lung ultrasound as a tool to guide respiratory physiotherapy" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:5 [ 0 => "R Vieira" 1 => "E Segura-Grau" 2 => "J Magalhães" 3 => "J Santos" 4 => "L Patrão" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "J Clin Ultrasound" "fecha" => "2020" "volumen" => "48" "numero" => "7" "paginaInicial" => "431" "paginaFinal" => "434" ] ] ] ] ] ] 35 => array:3 [ "identificador" => "bib0035" "etiqueta" => "36" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Is it a high time for a consensus on quantitative lung ultrasound approach?" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "DG Biasucci" 1 => "D Buonsenso" 2 => "DL. Grieco" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Minerva Anestesiol" "fecha" => "2022" "volumen" => "88" "numero" => "6" "paginaInicial" => "531" "paginaFinal" => "532" ] ] ] ] ] ] 36 => array:3 [ "identificador" => "bib0036" "etiqueta" => "37" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "A combined rapid clinical and lung ultrasound score for predicting bronchiolitis severity" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:3 [ 0 => "A. Camporesi" 1 => "R. Morello" 2 => "A. Guzzardella" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Intensive Care Med Paediatr Neonatal" "fecha" => "2023" "volumen" => "1" "numero" => "14" "paginaInicial" => "1" "paginaFinal" => "11" ] ] ] ] ] ] 37 => array:3 [ "identificador" => "bib0037" "etiqueta" => "38" "referencia" => array:1 [ 0 => array:1 [ "referenciaCompleta" => "Pouxtiaux G. Kinésithérapie Respiratorie de L'Enfant. Les téchniques de soins guidées par I'auscultation pulmonaire. 2ª edição. Belgique. De Boeck Université; 2000." ] ] ] 38 => array:3 [ "identificador" => "bib0038" "etiqueta" => "39" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Sarcomere number regulation maintained after immobilization in desmin-null mouse skeletal muscle" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "SB Shah" 1 => "D Peters" 2 => "KA Jordan" 3 => "DJ Milner" 4 => "J Fridén" 5 => "Y Capetanaki" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "J Exp Biol" "fecha" => "2001" "volumen" => "204" "numero" => "10" "paginaInicial" => "1703" "paginaFinal" => "1710" ] ] ] ] ] ] 39 => array:3 [ "identificador" => "bib0039" "etiqueta" => "40" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Manual hyperinflation in children" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "DM Lorena" 1 => "MCM Frade" 2 => "THD. Silva" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Rev Bras Ter Intensiva" "fecha" => "2022" "volumen" => "33" "numero" => "4" "paginaInicial" => "616" "paginaFinal" => "623" ] ] ] ] ] ] ] ] ] ] ] "idiomaDefecto" => "en" "url" => "/18075932/000000790000000C/v115_202410170932/S1807593224001716/v115_202410170932/en/main.assets" "Apartado" => array:4 [ "identificador" => "94924" "tipo" => "SECCION" "en" => array:2 [ "titulo" => "Original articles" "idiomaDefecto" => true ] "idiomaDefecto" => "en" ] "PDF" => "https://static.elsevier.es/multimedia/18075932/000000790000000C/v115_202410170932/S1807593224001716/v115_202410170932/en/main.pdf?idApp=UINPBA00004N&text.app=https://www.elsevier.es/" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1807593224001716?idApp=UINPBA00004N"]

Statistics

Original articles

Patrícia Aparecida Silva Camassutia,

Corresponding author

patriciascamassuti@gmail.com

Corresponding author.

, Cíntia Johnstona, Werther Brunow de Carvalhob, Michele Luglioc, Orlei Ribeiro de Araújod, Brenda Morrowe

a Postgraduate Program in Pediatrics, Department of Pediatrics, Universidade de São Paulo, São Paulo, SP, Brazil

b Department of Pediatrics, Universidade de São Paulo, São Paulo, SP, Brazil

c Children's Institute, Universidade de São Paulo, São Paulo, SP, Braziil

d Institute of Pediatric Oncology, Support Group for Adolescents and Children with Cancer (GRAACC), Universidade Federal de São Paulo, São Paulo, SP, Brazil

e Department of Paediatrics and Child Health, University of Cape Town: Rondebosch, Western Cape, ZA, South Africa

Read

227

Times
was read the article

105

Total PDF

122

Total HTML

Share statistics

 array:22 [
  "pii" => "S1807593224001716"
  "issn" => "18075932"
  "doi" => "10.1016/j.clinsp.2024.100494"
  "estado" => "S250"
  "fechaPublicacion" => "2024-01-01"
  "aid" => "100494"
  "copyright" => "HCFMUSP"
  "copyrightAnyo" => "2024"
  "documento" => "article"
  "crossmark" => 1
  "subdocumento" => "fla"
  "abierto" => array:3 [
    "ES" => false
    "ES2" => false
    "LATM" => false
  ]
  "gratuito" => false
  "lecturas" => array:1 [
    "total" => 0
  ]
  "itemSiguiente" => array:17 [
    "pii" => "S1807593224001765"
    "issn" => "18075932"
    "doi" => "10.1016/j.clinsp.2024.100499"
    "estado" => "S250"
    "fechaPublicacion" => "2024-01-01"
    "aid" => "100499"
    "copyright" => "HCFMUSP"
    "documento" => "article"
    "crossmark" => 1
    "subdocumento" => "fla"
    "abierto" => array:3 [
      "ES" => false
      "ES2" => false
      "LATM" => false
    ]
    "gratuito" => false
    "lecturas" => array:1 [
      "total" => 0
    ]
    "en" => array:12 [
      "idiomaDefecto" => true
      "cabecera" => "<span class="elsevierStyleTextfn">Original articles</span>"
      "titulo" => "Use of continuous positive airway pressure in drainage of pleural effusion&#58; Educational intervention for evidence-based practice"
      "tienePdf" => "en"
      "tieneTextoCompleto" => "en"
      "tieneResumen" => array:2 [
        0 => "en"
        1 => "en"
      ]
      "contieneResumen" => array:1 [
        "en" => true
      ]
      "contieneTextoCompleto" => array:1 [
        "en" => true
      ]
      "contienePdf" => array:1 [
        "en" => true
      ]
      "resumenGrafico" => array:2 [
        "original" => 0
        "multimedia" => array:8 [
          "identificador" => "fig0001"
          "etiqueta" => "Fig&#46; 1"
          "tipo" => "MULTIMEDIAFIGURA"
          "mostrarFloat" => true
          "mostrarDisplay" => false
          "figura" => array:1 [
            0 => array:4 [
              "imagen" => "gr1.jpeg"
              "Alto" => 1481
              "Ancho" => 2231
              "Tamanyo" => 150043
            ]
          ]
          "detalles" => array:1 [
            0 => array:3 [
              "identificador" => "alt0004"
              "detalle" => "Fig "
              "rol" => "short"
            ]
          ]
          "descripcion" => array:1 [
            "en" => "<p id="spara001" class="elsevierStyleSimplePara elsevierViewall">Study phases&#58; Phase I&#44; Baseline audit phase&#59; Phase II&#44; Implementation phase&#59; Phase III&#44; Post-intervention audit&#59; Phase IV&#44; Follow-up&#46; CSAT&#44; Clinical Sustainability Assessment Tool&#46;</p>"
          ]
        ]
      ]
      "autores" => array:1 [
        0 => array:2 [
          "autoresLista" => "Elinaldo da Concei&#231;&#227;o dos Santos, Adilson Mendes, Daniela Gon&#231;alves Ohara, Hiago Vinicius Costa Silva, Jh&#233;ssica Crhistina Veiga Nascimento, Jo&#227;o Paulo Rodrigues Pacheco, William Poncin, Gregory Reychler, Juliana Ribeiro Fonseca Franco de Macedo, Adriana Claudia Lunardi"
          "autores" => array:10 [
            0 => array:2 [
              "nombre" => "Elinaldo da Concei&#231;&#227;o dos"
              "apellidos" => "Santos"
            ]
            1 => array:2 [
              "nombre" => "Adilson"
              "apellidos" => "Mendes"
            ]
            2 => array:2 [
              "nombre" => "Daniela Gon&#231;alves"
              "apellidos" => "Ohara"
            ]
            3 => array:2 [
              "nombre" => "Hiago Vinicius Costa"
              "apellidos" => "Silva"
            ]
            4 => array:2 [
              "nombre" => "Jh&#233;ssica Crhistina Veiga"
              "apellidos" => "Nascimento"
            ]
            5 => array:2 [
              "nombre" => "Jo&#227;o Paulo Rodrigues"
              "apellidos" => "Pacheco"
            ]
            6 => array:2 [
              "nombre" => "William"
              "apellidos" => "Poncin"
            ]
            7 => array:2 [
              "nombre" => "Gregory"
              "apellidos" => "Reychler"
            ]
            8 => array:2 [
              "nombre" => "Juliana Ribeiro Fonseca Franco de"
              "apellidos" => "Macedo"
            ]
            9 => array:2 [
              "nombre" => "Adriana Claudia"
              "apellidos" => "Lunardi"
            ]
          ]
        ]
      ]
      "resumen" => array:1 [
        0 => array:3 [
          "titulo" => "Highlights"
          "clase" => "author-highlights"
          "resumen" => "<span id="abss0001" class="elsevierStyleSection elsevierViewall"><p id="spara008" class="elsevierStyleSimplePara elsevierViewall"><ul class="elsevierStyleList" id="celist0001"><li class="elsevierStyleListItem" id="celistitem0001"><span class="elsevierStyleLabel">&#8226;</span><p id="para0001" class="elsevierStylePara elsevierViewall">Educational interventions to update healthcare professionals on the importance of CPAP&#46;</p></li><li class="elsevierStyleListItem" id="celistitem0003"><span class="elsevierStyleLabel">&#8226;</span><p id="para0003" class="elsevierStylePara elsevierViewall">Continuing education needs to be implemented for better patient care&#46;</p></li><li class="elsevierStyleListItem" id="celistitem0004"><span class="elsevierStyleLabel">&#8226;</span><p id="para0004" class="elsevierStylePara elsevierViewall">An educational intervention may have some success in educating and updating healthcare professionals on the use of CPAP in patients with chest tubes due to pleural effusion&#46;</p></li><li class="elsevierStyleListItem" id="celistitem0005"><span class="elsevierStyleLabel">&#8226;</span><p id="para0005" class="elsevierStylePara elsevierViewall">Physical therapists need to be strongly encouraged to write down the details of the interventions they perform in patients&#39; medical records&#46;</p></li><li class="elsevierStyleListItem" id="celistitem0006"><span class="elsevierStyleLabel">&#8226;</span><p id="para0006" class="elsevierStylePara elsevierViewall">New strategies for continuing education of health professionals need to be developed so that the patient receives the best possible care&#46;</p></li></ul></p></span>"
        ]
      ]
    ]
    "idiomaDefecto" => "en"
    "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1807593224001765?idApp=UINPBA00004N"
    "url" => "/18075932/000000790000000C/v115_202410170932/S1807593224001765/v115_202410170932/en/main.assets"
  ]
  "itemAnterior" => array:17 [
    "pii" => "S1807593224001686"
    "issn" => "18075932"
    "doi" => "10.1016/j.clinsp.2024.100491"
    "estado" => "S250"
    "fechaPublicacion" => "2024-01-01"
    "aid" => "100491"
    "copyright" => "HCFMUSP"
    "documento" => "article"
    "crossmark" => 1
    "subdocumento" => "fla"
    "abierto" => array:3 [
      "ES" => false
      "ES2" => false
      "LATM" => false
    ]
    "gratuito" => false
    "lecturas" => array:1 [
      "total" => 0
    ]
    "en" => array:12 [
      "idiomaDefecto" => true
      "cabecera" => "<span class="elsevierStyleTextfn">Original articles</span>"
      "titulo" => "Changes in fluconazole pharmacokinetics can impact on antifungal effectiveness in critically ill burn patients&#58; a Pharmacokinetic-Pharmacodynamic &#40;PK&#47;PD&#41; approach"
      "tienePdf" => "en"
      "tieneTextoCompleto" => "en"
      "tieneResumen" => array:2 [
        0 => "en"
        1 => "en"
      ]
      "contieneResumen" => array:1 [
        "en" => true
      ]
      "contieneTextoCompleto" => array:1 [
        "en" => true
      ]
      "contienePdf" => array:1 [
        "en" => true
      ]
      "resumenGrafico" => array:2 [
        "original" => 0
        "multimedia" => array:8 [
          "identificador" => "fig0002"
          "etiqueta" => "Figure 2"
          "tipo" => "MULTIMEDIAFIGURA"
          "mostrarFloat" => true
          "mostrarDisplay" => false
          "figura" => array:1 [
            0 => array:4 [
              "imagen" => "gr2.jpeg"
              "Alto" => 1944
              "Ancho" => 2500
              "Tamanyo" => 223185
            ]
          ]
          "detalles" => array:1 [
            0 => array:3 [
              "identificador" => "alt0003"
              "detalle" => "Figure "
              "rol" => "short"
            ]
          ]
          "descripcion" => array:1 [
            "en" => "<p id="spara002" class="elsevierStyleSimplePara elsevierViewall">Fluconazole PK&#47;PD target attainment in the critically ill severely burned patients&#46; &#40;A&#41; AUC<span class="elsevierStyleSup">ss</span><span class="elsevierStyleInf">0-24h</span>&#47;MIC&#46; &#40;B&#41; <span class="elsevierStyleItalic">f</span>AUC<span class="elsevierStyleSup">ss</span><span class="elsevierStyleInf">0-24h</span>&#47;MIC&#46; Data from this study is presented as median &#40;interquartile range&#41;&#46; AUC<span class="elsevierStyleSup">ss</span><span class="elsevierStyleInf">0-24h</span>&#44; Area Under the Concentration-time curve of 24h&#59; <span class="elsevierStyleItalic">f</span>AUC<span class="elsevierStyleSup">ss</span><span class="elsevierStyleInf">0-24h</span>&#44; Area Under the free Concentration-time curve of 24h&#59; MIC&#44; Minimum Inhibitory Concentration&#59; TDM&#44; Therapeutic Drug Monitoring&#46;</p>"
          ]
        ]
      ]
      "autores" => array:1 [
        0 => array:2 [
          "autoresLista" => "Victor Kaneko Matsuno, Edvaldo Vieira de Campos, Elson Mendes da Silva Junior, Jo&#227;o Manoel da Silva Junior, David de Souza Gomez, Silvia Regina Cavani Jorge Santos"
          "autores" => array:6 [
            0 => array:2 [
              "nombre" => "Victor Kaneko"
              "apellidos" => "Matsuno"
            ]
            1 => array:2 [
              "nombre" => "Edvaldo Vieira de"
              "apellidos" => "Campos"
            ]
            2 => array:2 [
              "nombre" => "Elson Mendes da"
              "apellidos" => "Silva Junior"
            ]
            3 => array:2 [
              "nombre" => "Jo&#227;o Manoel da"
              "apellidos" => "Silva Junior"
            ]
            4 => array:2 [
              "nombre" => "David de Souza"
              "apellidos" => "Gomez"
            ]
            5 => array:2 [
              "nombre" => "Silvia Regina Cavani Jorge"
              "apellidos" => "Santos"
            ]
          ]
        ]
      ]
      "resumen" => array:1 [
        0 => array:3 [
          "titulo" => "Highlights"
          "clase" => "author-highlights"
          "resumen" => "<span id="abss0001" class="elsevierStyleSection elsevierViewall"><p id="spara006" class="elsevierStyleSimplePara elsevierViewall"><ul class="elsevierStyleList" id="celist0001"><li class="elsevierStyleListItem" id="celistitem0001"><span class="elsevierStyleLabel">&#8226;</span><p id="para0001" class="elsevierStylePara elsevierViewall">Fluconazole pharmacokinetics is significantly altered in critically ill burn patients&#46;</p></li><li class="elsevierStyleListItem" id="celistitem0002"><span class="elsevierStyleLabel">&#8226;</span><p id="para0002" class="elsevierStylePara elsevierViewall">Half-life and total body clearance were correlated to volume of distribution decrease&#46;</p></li><li class="elsevierStyleListItem" id="celistitem0003"><span class="elsevierStyleLabel">&#8226;</span><p id="para0003" class="elsevierStylePara elsevierViewall">High-dose fluconazole may be necessary to guarantee coverage against <span class="elsevierStyleItalic">Candida glabrata</span>&#46;</p></li></ul></p></span>"
        ]
      ]
    ]
    "idiomaDefecto" => "en"
    "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1807593224001686?idApp=UINPBA00004N"
    "url" => "/18075932/000000790000000C/v115_202410170932/S1807593224001686/v115_202410170932/en/main.assets"
  ]
  "en" => array:18 [
    "idiomaDefecto" => true
    "cabecera" => "<span class="elsevierStyleTextfn">Original articles</span>"
    "titulo" => "Structured respiratory physiotherapy protocol for resolution of atelectasis in pediatric intensive care"
    "tieneTextoCompleto" => true
    "autores" => array:1 [
      0 => array:4 [
        "autoresLista" => "Patr&#237;cia Aparecida Silva Camassuti, C&#237;ntia Johnston, Werther Brunow de Carvalho, Michele Luglio, Orlei Ribeiro de Ara&#250;jo, Brenda Morrow"
        "autores" => array:6 [
          0 => array:4 [
            "nombre" => "Patr&#237;cia Aparecida Silva"
            "apellidos" => "Camassuti"
            "email" => array:1 [
              0 => "patriciascamassuti@gmail.com"
            ]
            "referencia" => array:2 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">a</span>"
                "identificador" => "aff0001"
              ]
              1 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">&#42;</span>"
                "identificador" => "cor0001"
              ]
            ]
          ]
          1 => array:3 [
            "nombre" => "C&#237;ntia"
            "apellidos" => "Johnston"
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">a</span>"
                "identificador" => "aff0001"
              ]
            ]
          ]
          2 => array:3 [
            "nombre" => "Werther Brunow"
            "apellidos" => "de Carvalho"
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">b</span>"
                "identificador" => "aff0002"
              ]
            ]
          ]
          3 => array:3 [
            "nombre" => "Michele"
            "apellidos" => "Luglio"
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">c</span>"
                "identificador" => "aff0003"
              ]
            ]
          ]
          4 => array:3 [
            "nombre" => "Orlei Ribeiro"
            "apellidos" => "de Ara&#250;jo"
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">d</span>"
                "identificador" => "aff0004"
              ]
            ]
          ]
          5 => array:3 [
            "nombre" => "Brenda"
            "apellidos" => "Morrow"
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">e</span>"
                "identificador" => "aff0005"
              ]
            ]
          ]
        ]
        "afiliaciones" => array:5 [
          0 => array:3 [
            "entidad" => "Postgraduate Program in Pediatrics&#44; Department of Pediatrics&#44; Universidade de S&#227;o Paulo&#44; S&#227;o Paulo&#44; SP&#44; Brazil"
            "etiqueta" => "a"
            "identificador" => "aff0001"
          ]
          1 => array:3 [
            "entidad" => "Department of Pediatrics&#44; Universidade de S&#227;o Paulo&#44; S&#227;o Paulo&#44; SP&#44; Brazil"
            "etiqueta" => "b"
            "identificador" => "aff0002"
          ]
          2 => array:3 [
            "entidad" => "Children&#39;s Institute&#44; Universidade de S&#227;o Paulo&#44; S&#227;o Paulo&#44; SP&#44; Braziil"
            "etiqueta" => "c"
            "identificador" => "aff0003"
          ]
          3 => array:3 [
            "entidad" => "Institute of Pediatric Oncology&#44; Support Group for Adolescents and Children with Cancer &#40;GRAACC&#41;&#44; Universidade Federal de S&#227;o Paulo&#44; S&#227;o Paulo&#44; SP&#44; Brazil"
            "etiqueta" => "d"
            "identificador" => "aff0004"
          ]
          4 => array:3 [
            "entidad" => "Department of Paediatrics and Child Health&#44; University of Cape Town&#58; Rondebosch&#44; Western Cape&#44; ZA&#44; South Africa"
            "etiqueta" => "e"
            "identificador" => "aff0005"
          ]
        ]
        "correspondencia" => array:1 [
          0 => array:3 [
            "identificador" => "cor0001"
            "etiqueta" => "&#8270;"
            "correspondencia" => "Corresponding author&#46;"
          ]
        ]
      ]
    ]
    "resumenGrafico" => array:2 [
      "original" => 0
      "multimedia" => array:8 [
        "identificador" => "fig0003"
        "etiqueta" => "Fig&#46; 3"
        "tipo" => "MULTIMEDIAFIGURA"
        "mostrarFloat" => true
        "mostrarDisplay" => false
        "figura" => array:1 [
          0 => array:4 [
            "imagen" => "gr3.jpeg"
            "Alto" => 2967
            "Ancho" => 2833
            "Tamanyo" => 204203
          ]
        ]
        "detalles" => array:1 [
          0 => array:3 [
            "identificador" => "alt0007"
            "detalle" => "Fig "
            "rol" => "short"
          ]
        ]
        "descripcion" => array:1 [
          "en" => "<p id="spara003" class="elsevierStyleSimplePara elsevierViewall">Sample selection flowchart&#46;</p>"
        ]
      ]
    ]
    "textoCompleto" => "<span class="elsevierStyleSections"><span id="sec0001" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="cesectitle0004">Introduction</span><p id="para0005" class="elsevierStylePara elsevierViewall">Developing lungs are predisposed to collapse&#46;<a class="elsevierStyleCrossRef" href="#bib0001"><span class="elsevierStyleSup">1</span></a> Atelectasis is one of the most frequent pulmonary complications in children undergoing Invasive Mechanical Ventilation &#40;IMV&#41;&#46;<a class="elsevierStyleCrossRef" href="#bib0002"><span class="elsevierStyleSup">2</span></a></p><p id="para0006" class="elsevierStylePara elsevierViewall">Children are at higher risk of atelectasis&#44; owing to both obstruction and dynamic airway collapse&#44; due to their distinct anatomical and physiological features&#46; These predisposing features include smaller diameter&#44; less well-supported airways&#59; flexible&#47;compliant chest walls with relatively less compliant lungs&#59; and limited&#44; developing collateral ventilation channels&#46;<a class="elsevierStyleCrossRef" href="#bib0003"><span class="elsevierStyleSup">3</span></a></p><p id="para0007" class="elsevierStylePara elsevierViewall">In Pediatric Intensive Care Units &#40;PICUs&#41;&#44; more than 20&#37; of patients require IMV&#46;<a class="elsevierStyleCrossRef" href="#bib0004"><span class="elsevierStyleSup">4</span></a> The implementation of protective ventilation strategies with the use of low tidal volumes may&#44; in some cases&#44; contribute to the development of atelectasis secondary to insufficient inflation of the alveolar units&#46;<a class="elsevierStyleCrossRef" href="#bib0004"><span class="elsevierStyleSup">4</span></a></p><p id="para0008" class="elsevierStylePara elsevierViewall">In addition&#44; infection of the lower respiratory system is one of the leading causes of mortality in children under the age of five&#46;<a class="elsevierStyleCrossRef" href="#bib0005"><span class="elsevierStyleSup">5</span></a> During Lower Respiratory Tract Infections &#40;LRTI&#41;&#44; mucociliary clearance may be impaired by increased inflammation and&#47;or overload due to excessive mucus production&#44; with consequent impairment of ciliary function&#44; predisposing these patients to secondary complications such as pulmonary atelectasis&#46;<a class="elsevierStyleCrossRef" href="#bib0006"><span class="elsevierStyleSup">6</span></a></p><p id="para0009" class="elsevierStylePara elsevierViewall">Lung collapse may cause or exacerbate increased work of breathing&#44; hypoxemia&#44; hypercapnia&#44; and acute respiratory failure &#40;mild&#44; moderate&#44; or severe&#41;&#46;<a class="elsevierStyleCrossRef" href="#bib0007"><span class="elsevierStyleSup">7</span></a> Long-term complications of unresolved atelectasis include the development of bronchiectasis and chronic lung disease&#46; Early recognition and management of atelectasis are therefore essential to hasten resolution&#44; avoid adverse short and long-term sequelae&#44; and optimize clinical outcomes such as PICU and hospital length of stay and mortality&#46;<a class="elsevierStyleCrossRef" href="#bib0008"><span class="elsevierStyleSup">8</span></a></p><p id="para0010" class="elsevierStylePara elsevierViewall">The signs and symptoms of pulmonary atelectasis are often nonspecific&#44; however&#44; the application of imaging technologies has increased diagnostic sensitivity and specificity&#46;<a class="elsevierStyleCrossRef" href="#bib0009"><span class="elsevierStyleSup">9</span></a> Although chest X-Ray is still the gold standard for diagnosing atelectasis&#44; due to its cost and effectiveness&#44;<a class="elsevierStyleCrossRef" href="#bib0010"><span class="elsevierStyleSup">10</span></a> it has significant limitations including patient exposure to ionizing radiation&#44; relatively low sensitivity in detecting inflammatory lung lesions&#44; low negative predictive value&#44; and discrepancies in interpretation among specialists&#46;<a class="elsevierStyleCrossRef" href="#bib0011"><span class="elsevierStyleSup">11</span></a></p><p id="para0011" class="elsevierStylePara elsevierViewall">In view of the limitations of radiography&#44; the use of Point of Care Lung Ultrasound &#40;POCLUS&#41; has been proposed as an additional tool for identifying and monitoring pulmonary atelectasis in children&#46; Among the advantages are the low associated financial costs&#59; clinical utility of trained healthcare professionals being able to easily and quickly perform the test at the bedside&#59; and avoidance of harmful ionizing radiation&#44; allowing multiple repeated scans if needed to determine progression and&#47;or response to therapy&#46;<a class="elsevierStyleCrossRef" href="#bib0012"><span class="elsevierStyleSup">12</span></a></p><p id="para0012" class="elsevierStylePara elsevierViewall">The interventions used in the treatment of pulmonary atelectasis in intubated children are limited and&#44; to date&#44; there are no clinical trials that identify the most efficient treatment for the resolution of pulmonary atelectasis in pediatrics and neonatology&#46;<a class="elsevierStyleCrossRef" href="#bib0009"><span class="elsevierStyleSup">9</span></a></p><p id="para0013" class="elsevierStylePara elsevierViewall">Chest physiotherapy in patients with pulmonary atelectasis is a minimally invasive treatment that aims to maintain or improve airway patency by removing obstructive secretions&#44; reducing airway resistance&#44; promoting gas exchange&#44; and decreasing the work of breathing&#46;<a class="elsevierStyleCrossRef" href="#bib0013"><span class="elsevierStyleSup">13</span></a></p><p id="para0014" class="elsevierStylePara elsevierViewall">Although respiratory physiotherapy interventions include several techniques for the treatment of atelectasis&#44; there are only four studies<a class="elsevierStyleCrossRefs" href="#bib0014"><span class="elsevierStyleSup">14&#8211;17</span></a> that cite different methods of respiratory physiotherapy aimed at resolving atelectasis in pediatric patients on IMV&#46; However&#44; none of them are randomized controlled trials and none use standardized&#44; protocol-driven interventions&#46;</p><p id="para0015" class="elsevierStylePara elsevierViewall">Therefore&#44; the main objective of this study was to develop and analyze the clinical and imaging effects of a Structured Respiratory Physiotherapy Protocol &#40;SRRP&#41; for airway clearance and lung reexpansion in children on IMV diagnosed with unilateral pulmonary atelectasis&#46;</p></span><span id="sec0002" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="cesectitle0005">Materials and methods</span><span id="sec0003" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="cesectitle0006">Study design and population</span><p id="para0016" class="elsevierStylePara elsevierViewall">This was a prospective randomized controlled clinical trial&#44; registered in the Brazilian Clinical Trials Registry &#40;ReBEC&#41;&#58; RBR-106bhfwy&#44; carried out in the PICU of the Menino Jesus Municipal Children&#39;s Hospital &#40;HMIMJ&#41;&#44; in S&#227;o Paulo&#44; from October 2020 to March 2022&#46; The study was approved by the Research Ethics Committee of the University of S&#227;o Paulo School of Medicine &#40;FMUSP&#41; and by the Research Ethics Committee of the HMIMJ &#40;opinion 3&#44;689&#44;413&#41;&#46; The study started after its approval&#46;</p><p id="para0017" class="elsevierStylePara elsevierViewall">The study included 30 infants &#40;age&#58; 28 days to 24 months&#41; on IMV for a period greater than or equal to 12 hours through an orotracheal cannula&#44; diagnosed with pulmonary atelectasis by a pediatric intensive care physician through clinical examination and imaging &#40;chest X-Ray and POCLUS&#41;&#44; whose legal guardians had authorized the child&#39;s participation in the study through the Free and Informed Consent Form &#40;ICF&#41;&#46; Exclusion criteria included&#58; patients with bilateral atelectasis&#59; any type of air leak syndrome&#59; pulmonary hemorrhage&#59; presence of diseases presenting with bone fragility&#59; rib cage and&#47;or pulmonary contusions&#59; subcutaneous pacemakers&#59; treatment with anticoagulants for more than 72 continuous hours&#59; hemodynamic instability&#59; thrombocytopenia &#40;platelet count &#60; 50&#44;000&#41;&#59; presence of an intercostal chest drain&#59; underlying neuromuscular or cardiac diseases and presence of spinal deformities&#46;</p><p id="para0018" class="elsevierStylePara elsevierViewall">Patients who met the inclusion criteria were electronically randomized &#40;<a href="https://www.random.org/lists/">https&#58;&#47;&#47;www&#46;random&#46;org&#47;lists&#47;</a>&#41; into two groups&#58; Control Group &#40;CG&#41; and Intervention Group &#40;IG&#41; as described in <a class="elsevierStyleCrossRef" href="#fig0001">Fig&#46; 1</a>&#46;</p><elsevierMultimedia ident="fig0001"></elsevierMultimedia><p id="para0019" class="elsevierStylePara elsevierViewall">The sample size was calculated based on historical audit data from the study site &#8210; between August and December 2018&#44; 49 patients underwent tracheal intubation in this PICU&#44; with 13 of these patients developing pulmonary atelectasis&#46; It was therefore estimated that over a period of 12 months&#44; approximately 26&#8210;30 patients would develop pulmonary atelectasis&#46; When entered into a power analysis &#40;using the statistical program openepi&#46;com&#41;&#44; with equal numbers in the Intervention &#40;IG&#41; and Control &#40;CG&#41; groups&#44; a sample of 30 patients &#40;15 each in IG and CG&#41; yielded a statistical power of 80&#37;&#44; with 20&#37; error&#46;</p><p id="para0020" class="elsevierStylePara elsevierViewall">In order to characterize the sample&#44; the following data were collected from the patient&#39;s medical records&#58; age&#44; gender&#44; clinical diagnosis of hospitalization&#44; weight&#44; height&#44; laboratory tests&#44; and the Pediatric Index of Mortality 2 &#40;PIM 2&#41; outcome prediction score&#46;</p><p id="para0021" class="elsevierStylePara elsevierViewall">Data collection was performed by the physical therapist responsible for the study&#46; Upon detecting the presence of atelectasis on the chest X-Ray&#44; the pediatric intensive care physician responsible for the PICU called the physical therapist via cell phone&#46; After the activation&#44; the researcher checked whether the patient met the inclusion criteria of the study&#46; If so&#44; the authorization of the legal guardian was requested to allow the child&#39;s participation in the study through the informed consent form&#46; After signing the informed consent form&#44; the patient was electronically randomized into CG or IG&#46;</p></span><span id="sec0004" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="cesectitle0007">Chest X-ray</span><p id="para0022" class="elsevierStylePara elsevierViewall">The baseline anteroposterior radiological images were considered to be free of atelectasis when there was normal pulmonary transparency with free costophrenic sinuses visualized&#46; Lobar or segmental atelectasis was considered when opacification of the lobe or lung segment was present with any of the following concomitant signs&#58; loss of air&#47;gas volume&#44; the most direct sign being the displacement of the interlobar fissure&#59; the deviation of the heart and mediastinum and the elevation of the diaphragm to the same side as atelectasis in extensive collapse&#46;<a class="elsevierStyleCrossRef" href="#bib0017"><span class="elsevierStyleSup">18</span></a></p><p id="para0023" class="elsevierStylePara elsevierViewall">The Radiological Atelectasis Scoring System was used to score atelectasis observed on lung X-Rays&#46;<a class="elsevierStyleCrossRef" href="#bib0018"><span class="elsevierStyleSup">19</span></a> Each radiograph was scored by the physiotherapist for atelectasis&#44; hyperinflation&#44; and mediastinal displacement&#46; The presence or absence of pulmonary hyperinflation was each marked as one &#40;1&#41; point or zero &#40;0&#41; points&#44; respectively&#46; The presence or absence of a mediastinal deviation was scored as one &#40;1&#41; or zero &#40;0&#41;&#46; Atelectasis was scored for each lung lobe&#46; Partial atelectasis of one lung lobe was scored as one &#40;1&#41; point&#44; and complete atelectasis of one lobe was scored as two &#40;2&#41; points&#46; The scores were summed for the chest X-Ray of each patient&#46;</p></span><span id="sec0005" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="cesectitle0008">Point of care lung ultrasound &#40;POCLUS&#41;</span><p id="para0024" class="elsevierStylePara elsevierViewall">Lung ultrasound was performed immediately before initiating interventions &#40;baseline&#41; and repeated 30 minutes after intervention &#40;post-intervention measure&#41;&#46; The assessment was performed by the main researcher&#44; a physiotherapist trained and certified to perform lung ultrasound&#46; The POCLUS images were recorded and subsequently analyzed by an independent evaluator blinded to study allocation and patient history&#46; The independent evaluator was a pediatric intensive care physician with ultrasonography certification and extensive clinical experience over more than eight years&#46;</p><p id="para0025" class="elsevierStylePara elsevierViewall">The lung was scanned antero-posteriorly&#44; craniocaudally&#44; transversely&#44; and longitudinally to the costal arches&#46; Initially&#44; POCLUS was performed with the patient in the supine position and subsequently turned laterally to evaluate the posterior pulmonary region&#46;</p><p id="para0026" class="elsevierStylePara elsevierViewall">The ultrasound image was considered unaltered when it showed an association between pleural sliding and the presence of horizontal repeats of the pleural line called &#8220;A-lines&#8221;&#46; A-lines are a type of reflection artifact originating from the pleural line&#44; seen as a series of hyperechoic parallel lines&#44; equidistant from each other&#44; below the pleural line&#44; with spacing equal to the distance between the skin and the pleural line&#46;<a class="elsevierStyleCrossRef" href="#bib0012"><span class="elsevierStyleSup">12</span></a></p><p id="para0027" class="elsevierStylePara elsevierViewall">The main imaging characteristics of atelectasis visualized by ultrasound are loss of aeration generating a visible&#44; hyperechoic parenchymal area&#44; which may present ill-defined and irregular borders&#59; large lung consolidations with static bronchograms&#59; whilst dynamic air bronchogram can rule out atelectasis&#46;<a class="elsevierStyleCrossRef" href="#bib0019"><span class="elsevierStyleSup">20</span></a> Other signs of atelectasis on POCLUS include abnormalities in the pleural line and disappearance of the A-line&#46;<a class="elsevierStyleCrossRef" href="#bib0020"><span class="elsevierStyleSup">21</span></a> The coalescent B-line &#40;or B-pattern&#41; can be interpreted as a higher degree of severity or a state prior to the development of atelectasis&#44; especially if the lesion has a focal location&#46;<a class="elsevierStyleCrossRef" href="#bib0021"><span class="elsevierStyleSup">22</span></a> The B-lines are hyperechoic vertical artifacts originating from the pleural line that extends to the periphery of the lung field and move with the pulmonary sliding&#46;<a class="elsevierStyleCrossRef" href="#bib0022"><span class="elsevierStyleSup">23</span></a> At the point of intersection&#44; the B-lines obliterate the A-lines&#46;</p><p id="para0028" class="elsevierStylePara elsevierViewall">The loss of lung aeration identified at POCLUS was graded using the Lung Ultrasound Score &#40;LUS&#41;&#44; validated for this purpose&#46;<a class="elsevierStyleCrossRef" href="#bib0023"><span class="elsevierStyleSup">24</span></a> A score of 0 indicates normal aeration i&#46;e&#46;&#44; the presence of lung slippage and horizontal A-lines&#44; or less than three vertical B-lines&#59; a score of 1 indicates moderate loss of aeration indicated by the presence of &#8805;3 B-lines&#44; regularly or irregularly spaced&#44; originating from the pleural line or small juxta pleural consolidations&#59; a score of 2 indicates severe loss of aeration&#44; i&#46;e&#46;&#59; the presence of coalescing B-lines in several intercostal spaces&#44; occupying the entire intercostal space&#59; and a score of 3 indicates complete loss of pulmonary aeration&#44; characterized by the presence of tissue echogenicity and static or dynamic air bronchograms&#44; as observed in lung consolidation&#46;</p></span><span id="sec0006" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="cesectitle0009">Monitoring</span><p id="para0029" class="elsevierStylePara elsevierViewall">Patients in both groups had vital sign measurements assessed at baseline &#40;immediately before intervention&#41; and at 10 and 30 minutes after intervention&#58; and underwent three evaluations Heart Rate &#40;HR&#41;&#59; Respiratory Rate &#40;RR&#41;&#59; body temperature&#59; PA&#59; SpO<span class="elsevierStyleInf">2</span>&#46; Clinical severity was classified according to the Wood-Downes Score &#40;WD&#41;<a class="elsevierStyleCrossRef" href="#bib0024"><span class="elsevierStyleSup">25</span></a> as mild &#40;1 to 3 points&#41;&#44; moderate &#40;4 to 7 points&#41; and severe &#40;8 to 14 points&#41; according to the sum of the following items&#58; the presence of wheezing &#40;0 &#61; No&#59; 1 &#61; End of expiration&#59; 2 &#61; Full expiration&#59; 3 &#61; Inhalation and expiration&#41;&#59; the presence of chest indrawing &#40;No &#61; 0&#59; Subcostal &#61; 1&#59; Supraclavicular subcostal and nasal flare &#61; 2&#59; supraclavicular&#44; subcostal&#44; intercostal&#44; suprasternal&#44; and nasal flare &#61; 3&#41;&#59; total respiratory rate &#40;&#60; 30 breaths per minute &#61; 0&#59; 31&#8210;45 &#61; 1&#59; 46&#8210;60 &#61; 2&#59; &#62; 60 &#61; 3&#41;&#59; heart rate &#40;&#60; 120 beats per minute &#61; 0&#59; &#62; 120 &#61; 1&#41;&#59; ventilation and breath sound on auscultation &#40;0 &#61; Good and symmetrical breath sounds&#59; 1 &#61; Regular and symmetrical&#59; 2 &#61; Very decreased breath sounds&#59; 3 &#61; Silent chest and cyanosis &#40;0 &#61; No&#59; 1 &#61; Yes&#41;&#46;</p><p id="para0030" class="elsevierStylePara elsevierViewall">During monitoring&#44; the number of aspirations&#44; quantity&#44; and quality of aspirated tracheal secretion were recorded&#44; according to the Suzukava Method&#58;<a class="elsevierStyleCrossRef" href="#bib0025"><span class="elsevierStyleSup">26</span></a> Fluid when the aspiration tube is free of secretions after aspiration&#44; using only vacuum&#59; Moderate&#44; when the aspiration tube presents secretions adhered to the wall of the probe after aspiration but is free after the use of 0&#46;9&#37; saline solution&#59; Thick&#44; when the aspiration probe has secretions adhered to the probe wall even after instillation of 0&#46;9&#37; saline solution&#46;</p></span><span id="sec0007" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="cesectitle0010">Control group</span><p id="para0031" class="elsevierStylePara elsevierViewall">The CG was submitted to routine respiratory physiotherapy care and interventions of the Physical Therapy Service&#44; including manual vibration of the patient&#39;s chest wall and Manual Hyperinflation &#40;MH&#41; with a self-inflating bag without control of Peak Inspiratory Pressure &#40;PIP&#41;&#44; number of repetitions or established intervals&#46;</p><p id="para0032" class="elsevierStylePara elsevierViewall">The technique of manual vibration in the chest is based on the properties of modifying the consistency of airway mucus&#46; This thixotropic gel&#44; highly viscous under static conditions can become less viscous and is able to flow when shaken&#46;<a class="elsevierStyleCrossRef" href="#bib0026"><span class="elsevierStyleSup">27</span></a> Thus&#44; when applying vibrations to the chest wall&#44; mechanical energy is transmitted to the airways aiding the ciliary beating&#44; thus reducing the viscosity of bronchial secretions&#44; which can be more easily eliminated by positioning&#44; coughing&#44; or aspiration of the airways&#46;<a class="elsevierStyleCrossRef" href="#bib0027"><span class="elsevierStyleSup">28</span></a></p><p id="para0033" class="elsevierStylePara elsevierViewall">Manual Hyperinflation &#40;MH&#41; aims to mobilize pulmonary secretions proximally by increasing Peak Expiratory Flow &#40;PEF&#41; and promoting pulmonary re-expansion by increasing pulmonary distension pressure&#44; which favors increased airflow to the poorly ventilated regions through the collateral channels &#40;where present&#41; and by redistributing and renewing surfactant in the alveoli&#46;<a class="elsevierStyleCrossRef" href="#bib0028"><span class="elsevierStyleSup">29</span></a> The technique is performed by applying a series of deep manual insufflations with brief inspiratory pauses&#44; followed by a rapid release of the bag to increase expiratory flow and stimulate coughing&#46;<a class="elsevierStyleCrossRef" href="#bib0027"><span class="elsevierStyleSup">28</span></a></p></span><span id="sec0008" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="cesectitle0011">Intervention group</span><p id="para0034" class="elsevierStylePara elsevierViewall">The IG was submitted only to the SRPP developed for this study and applied by the main research physiotherapist&#46; The SRPP intervention included modified postural drainage with mechanical chest wall vibration applied using an electronic massage device &#40;Super da G-Life&#174;&#41;&#59; MH using a self-inflating bag&#59; stretching of the respiratory muscles&#59; and functional positioning of the patient in bed&#46;</p><p id="para0035" class="elsevierStylePara elsevierViewall">The patient was first positioned with elevation of the head of the bed by 30&#176; in lateral decubitus&#44; so that the atelectatic pulmonary region was non-dependent&#44; maintaining this position during the application of the other interventions&#46;</p><p id="para0036" class="elsevierStylePara elsevierViewall">Mechanical vibration over the chest wall was performed with the use of a massager positioned over the atelectatic region&#44; in the craniocaudal and lateromedial directions&#44; for ten minutes&#44; with a frequency of 50 Hertz &#40;Hz&#41;&#46;<a class="elsevierStyleCrossRef" href="#bib0015"><span class="elsevierStyleSup">15</span></a> Manual hyperinflation with a self-inflating bag consisted of slow and deep inflation of the bag&#44; followed by an inspiratory pause of two to three seconds and rapid release after this period<a class="elsevierStyleCrossRef" href="#bib0028"><span class="elsevierStyleSup">29</span></a> with oxygen flow at five liters per minute&#44; with 10 repetitions&#46;<a class="elsevierStyleCrossRef" href="#bib0014"><span class="elsevierStyleSup">14</span></a> To monitor the PIP provided during MH&#44; a Murenas&#174; analog manometer was used&#44; not exceeding the PIP of 30 cm H<span class="elsevierStyleInf">2</span>O&#46;<a class="elsevierStyleCrossRef" href="#bib0028"><span class="elsevierStyleSup">29</span></a> No PEEP valve was used&#46;</p><p id="para0037" class="elsevierStylePara elsevierViewall">After performing MH&#44; the patients&#8217; accessory respiratory muscles were stretched by the physiotherapist throughout the expiratory phase&#44; bringing the muscle to maximum length&#44; with two sets in 10 consecutive respiratory cycles for each muscle&#44; with a five-second interval between each set&#46;<a class="elsevierStyleCrossRef" href="#bib0029"><span class="elsevierStyleSup">30</span></a> The stretches were performed bilaterally as follows&#58; upper trapezius&#58; with the patient positioned in the dorsal decubitus position&#44; the physiotherapist rested one hand on the occipital region&#44; side flexing the head to the opposite side whilst&#44; with the other hand&#44; moving the ipsilateral shoulder in the craniocaudal direction&#59; sternocleidomastoid&#58; with the patient positioned in the dorsal decubitus position&#44; the physiotherapist passively flexed &#40;away from the muscle to be stretched&#41; and laterally rotated towards the target muscle&#44; by placing one hand in the occipital region and the other on the upper thorax region&#44; displacing in the craniocaudal direction&#59; pectoralis major&#58; with the patient positioned in dorsal decubitus&#44; with the arm to be stretched abducted and externally rotated at the shoulder&#44; with elbow flexion&#44; the physiotherapist applied a passive stretch by applying pressure using one hand on the upper third of the arm and the other on the lateral region of the upper thorax&#44; following the orientation of the muscle fibers&#59; intercostal muscles&#58; with the patient in lateral decubitus with the forearm flexed and the hand resting on the occiput&#44; the physiotherapist supported the patient&#39;s arm with one hand while the other was positioned on the lower rib cage during inspiration&#59; the physiotherapist facilitated expansion of the rib cage by moving the patient&#39;s arm in the craniocaudal direction and following the expiratory movement without applying pressure &#40;<a class="elsevierStyleCrossRef" href="#fig0002">Fig&#46; 2</a>&#41;&#46;<a class="elsevierStyleCrossRef" href="#bib0029"><span class="elsevierStyleSup">30</span></a></p><elsevierMultimedia ident="fig0002"></elsevierMultimedia><p id="para0038" class="elsevierStylePara elsevierViewall">In both groups&#44; the orotracheal tube was aspirated&#44; when necessary&#44; after the interventions and during the procedures&#46; The quantity and quality of aspirated tracheal secretion were classified using the Suzukava method&#46;<a class="elsevierStyleCrossRef" href="#bib0025"><span class="elsevierStyleSup">26</span></a></p><p id="para0039" class="elsevierStylePara elsevierViewall">Finally&#44; functional positioning was performed in bed&#44; aiming to favor respiratory mechanics&#44; optimize pulmonary function&#44; and stimulate the child&#39;s sensorineural and psychomotor development&#46;</p></span><span id="sec0009" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="cesectitle0012">Interrupt criteria</span><p id="para0040" class="elsevierStylePara elsevierViewall">The criteria for interruption of the protocol were&#58; Heart Rate &#40;HR&#41; greater than 200 beats per minute &#40;bpm&#41;&#59; Respiratory Rate &#40;RR&#41; greater than 45 breaths per minute &#40;bpm&#41;&#59; Blood Pressure &#40;BP&#41; values above 120&#47;80 millimeters of mercury &#40;mmHg&#41; or less than 80&#47;40 mmHg&#59; Pulse Oxygen Saturation &#40;SpO<span class="elsevierStyleInf">2</span>&#41; less than 88&#37; with the need for increased FiO<span class="elsevierStyleInf">2</span> during the application of the protocol&#46; The presence or absence of signs of respiratory distress &#40;accessory respiratory muscle use&#44; pallor&#44; sweating&#44; and psychomotor agitation&#41; was also considered according to the Wood-Downes Score &#40;WD&#41; used in this study&#46;<a class="elsevierStyleCrossRef" href="#bib0025"><span class="elsevierStyleSup">26</span></a> In the presence of any changes mentioned above&#44; the protocol was interrupted&#44; and the child was placed in bed and kept under monitoring&#46; The patient who needed to interrupt the procedures could be included again in the study six hours after interrupting the first attempt&#46; Daily attempts could be made&#44; within 48 hours of the first attempt&#44; after this period the patient was considered as not benefiting from the study protocol&#46;</p></span><span id="sec0010" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="cesectitle0013">Statistical analysis</span><p id="para0041" class="elsevierStylePara elsevierViewall">Descriptive statistics included measures of central tendency by means &#177; Standard Deviations &#40;SD&#41;&#44; medians and interquartile ranges &#40;IQR 25&#37;&#8210;75&#37;&#41;&#44; and absolute and relative frequencies&#46;</p><p id="para0042" class="elsevierStylePara elsevierViewall">The Kolmogorov-Smirnov test was used to evaluate the normality of the distribution&#44; and considering that most variables were not normally distributed&#44; between-group analyses were conducted using the non-parametric Wilcoxon&#47;Mann-Whitney tests&#46; Fisher&#39;s exact tests were used for comparisons between frequencies&#46; To compare repeated vital sign measurements &#40;before physical therapy&#44; after 10 and 30 minutes&#41;&#44; the non-parametric Friedman test was used&#44; with post-hoc analysis using the paired Wilcoxon test &#40;signed rank&#41;&#46; Bonferroni correction was used as appropriate&#46;</p></span><span id="sec0011" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="cesectitle0014">Evaluation of the magnitude of the effect &#40;effect size&#41;</span><p id="para0043" class="elsevierStylePara elsevierViewall">The intervention of the study was not compared to a placebo&#44; but to a control group&#44; in which routine physical therapy of the Hospital was performed&#46; Therefore&#44; statistical differences were not expected in the two groups when comparing parameters before and after respiratory therapy&#44; and the only way to evaluate the outcome of the study intervention is through the magnitude of the effect &#40;effect size&#41;&#46; The standardized effect magnitude allows researchers to communicate the practical significance of the results&#44; rather than just reporting statistical significance&#46;<a class="elsevierStyleCrossRef" href="#bib0030"><span class="elsevierStyleSup">31</span></a> Cohen&#39;s &#8220;<span class="elsevierStyleItalic">d</span>&#8221; test &#40;Cohens&#39; d&#41; is used to describe the standardized mean difference of an effect&#46; A correction of Cohens&#39; d is Hedges&#39; &#8220;<span class="elsevierStyleItalic">g</span>&#8221; &#40;Hedges&#39; g&#41;&#44; which is unbiased and corrected for small samples &#40;n &#60; 20&#41;&#44; and it was this test that the authors used to measure the effect of the intervention on the LUS and Wood Downes scores &#40;paired measures before and after respiratory physiotherapy&#41;&#46; The way to interpret the Hedges&#39; g is as suggested by Cohen&#58; small &#40;0&#46;2 &#60; Hedges&#39; g &#60; 0&#46;5&#41;&#44; moderate &#40;0&#46;5 &#60; Hedges&#39; g &#60; 0&#46;8&#41;&#44; and large &#40;Hedges&#39; g &#8805; 0&#46;8 effects&#41;&#46;<a class="elsevierStyleCrossRef" href="#bib0030"><span class="elsevierStyleSup">31</span></a> These values assume negative values when the effect is reduced&#44; e&#46;g&#46;&#44; a reduction in a score&#59; but they can be informed by their absolute values&#46; If the absolute value is greater than one &#40;1&#41;&#44; it means that the difference between the means is greater than one SD&#46;</p><p id="para0044" class="elsevierStylePara elsevierViewall">The analyses were performed using R&#58; A language and environment for statistical computing&#46; R Foundation for Statistical Computing&#44; Vienna&#44; Austria&#46; URL <a href="https://www.R-project.org/">https&#58;&#47;&#47;www&#46;R-project&#46;org&#47;</a>&#46;</p></span></span><span id="sec0012" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="cesectitle0015">Results</span><p id="para0045" class="elsevierStylePara elsevierViewall">During the study period&#44; 845 children were admitted to the PICU of the HMIMJ&#44; of which 26&#37; underwent orotracheal intubation and 7&#37; developed pulmonary atelectasis&#46; Of these children&#44; 40 met the inclusion criteria due to atelectasis&#44; 10 patients were excluded &#40;one with scoliosis&#44; two with orotracheal tube displacement&#44; tissue trauma&#44; air leak syndrome &#40;pneumothorax or pneumomediastinum&#41; &#40;<a class="elsevierStyleCrossRef" href="#fig0003">Fig&#46; 3</a>&#41;&#46;</p><elsevierMultimedia ident="fig0003"></elsevierMultimedia><p id="para0046" class="elsevierStylePara elsevierViewall">The sample of 30 children was randomized into two groups &#40;n &#61; 15 in the CG&#59; n &#61; 15 in the IG&#41;&#46; The median &#40;IQR 25&#37;&#8210;75&#37;&#41; age of the patients was 7 &#40;2&#8210;17&#41; months in the CG and 4 &#40;2&#8210;13&#46;5&#41; months in the IG&#46; The groups presented similar characteristics &#40;p &#62; 0&#46;05&#41; in terms of epidemiology and clinical variables &#40;<a class="elsevierStyleCrossRef" href="#tbl0001">Table 1</a>&#41;&#46;</p><elsevierMultimedia ident="tbl0001"></elsevierMultimedia><p id="para0047" class="elsevierStylePara elsevierViewall">Laboratory parameters prior to respiratory therapy interventions were statistically similar &#40;p &#62; 0&#46;05&#41;&#44; see <a class="elsevierStyleCrossRef" href="#tbl0001">Table 1</a>&#46; Ventilatory parameters and Radiological Atelectasis Scoring System scores of both groups were similar &#40;p &#62; 0&#46;05&#41;&#44; see <a class="elsevierStyleCrossRef" href="#tbl0002">Table 2</a>&#46; Regarding the variables diagnostics&#44; viral panel&#44; IMV mode&#44; VAP&#44; location of atelectasis&#44; quality and color of secretion&#44; it was not possible to add statistical significance due to the small sample size in the subcategories of each of them&#46;</p><elsevierMultimedia ident="tbl0002"></elsevierMultimedia><span id="sec0013" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="cesectitle0016">Evaluation of lung ultrasound score &#40;LUS&#41; and Wood-Downes &#40;WD&#41; scores</span><p id="para0048" class="elsevierStylePara elsevierViewall">There was no significant difference in the baseline or post-intervention median &#40;IQ 25&#37;&#8210;75&#37;&#41; LUS scores between the control and intervention groups&#58; 2 &#40;1&#8210;3&#41; vs&#46; 3 &#40;2&#8210;3&#41; &#40;p &#61; 0&#46;21&#41; and 1 &#40;1&#8210;2&#46;5&#41; vs&#46; 1 &#40;0&#46;5&#8210;2&#41; &#40;p &#61; 0&#46;5&#41; respectively&#46; Similarly&#44; there were no significant between-group differences in the median &#40;IQ 25&#37;&#8210;75&#37;&#41; baseline or post-intervention WD scores between CG and IG&#58; 4 &#40;3&#8210;5&#41; vs&#46; 4 &#40;3&#8210;5&#41; &#40;p &#61; 0&#46;9&#41; and 3 &#40;2&#8210;3&#41; vs&#46; 2 &#40;1&#8211;2&#46;5&#41; &#40;p &#61; 0&#46;18&#41;&#44; respectively&#46;</p><p id="para0049" class="elsevierStylePara elsevierViewall">Significant within-group differences were observed in both CG and IG comparing baseline to post-intervention measures &#40;<a class="elsevierStyleCrossRef" href="#tbl0003">Table 3</a>&#41;&#46; Median &#40;IQR 25&#37;&#8210;75&#37;&#41; LUS in the CG and IG changed from 2&#40;1&#8211;3&#41; and 3 &#40;2&#8211;3&#41; before respiratory physiotherapy to 1 &#40;1&#8211;2&#46;5&#59; p &#61; 0&#46;01&#41; and 1 &#40;0&#46;5&#8211;2&#59; p &#60; 0&#46;001&#41; after intervention respectively&#46; Median &#40;IQ 25&#37;&#8211;75&#37; WD score changed from 4 &#40;3&#46;5&#8210;5&#41; and 4 &#40;3&#8211;5&#41; to 3&#40;2&#8211;3&#59; p &#60; 0&#46;001&#41; and 2 &#40;1&#8211;2&#46;5&#59; p &#60; 0&#46;001&#41; postintervention in the control and intervention groups respectively&#46;</p><elsevierMultimedia ident="tbl0003"></elsevierMultimedia></span><span id="sec0014" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="cesectitle0017">Assessment of the magnitude of the effect</span><p id="para0050" class="elsevierStylePara elsevierViewall">There was a moderate effect on the reduction of the LUS score in the CG after respiratory physiotherapy &#40;Hedges&#39; g &#61; -0&#46;64&#44; 95&#37; CI&#58; -1&#46;35 to 0&#46;08&#41;&#44; and a 2&#46;9-fold greater effect on the IG &#40;Hedges&#39; g &#61; -1&#46;88&#44; 95&#37; CI&#58; -1&#46;01 to -2&#46;73&#41;&#44; characterizing a large effect on the reduction of this score &#40;<a class="elsevierStyleCrossRef" href="#fig0004">Fig&#46; 4</a>&#41;&#46;</p><elsevierMultimedia ident="fig0004"></elsevierMultimedia><p id="para0051" class="elsevierStylePara elsevierViewall">There was a large effect on the reduction of the WD score in the CG after physical therapy &#40;Hedges&#39; g &#61; -1&#46;53&#44; 95&#37; CI -3&#46;1 to -1&#46;29&#41;&#44; and a 1&#46;4-fold greater effect in the IG &#40;Hedges&#39; g &#61; -2&#46;2&#44; 95&#37; CI&#58; -2&#46;32 to -0&#46;71&#41; &#40;<a class="elsevierStyleCrossRef" href="#fig0005">Fig&#46; 5</a>&#41;&#46;</p><elsevierMultimedia ident="fig0005"></elsevierMultimedia></span><span id="sec0015" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="cesectitle0018">Evaluation of effects on physiological parameters</span><p id="para0052" class="elsevierStylePara elsevierViewall">The parameters of heart rate&#44; respiratory rate&#44; temperature&#44; SpO<span class="elsevierStyleInf">2</span>&#44; systolic&#44; mean&#44; and diastolic blood pressure at all measurement points were statistically similar between CG and IG &#40;<a class="elsevierStyleCrossRef" href="#tbl0004">Table 4</a>&#41;&#46;</p><elsevierMultimedia ident="tbl0004"></elsevierMultimedia></span></span><span id="sec0016" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="cesectitle0019">Discussion</span><p id="para0053" class="elsevierStylePara elsevierViewall">The loss of lung volume caused by atelectasis can modify respiratory mechanics and impair gas exchange&#44; which can lead to an increase in IMV time&#44; tracheal extubation failure&#44; increased length of hospital stays&#44; and morbidity and mortality&#46;<a class="elsevierStyleCrossRef" href="#bib0031"><span class="elsevierStyleSup">32</span></a> This study&#44; including children undergoing IMV&#44; evaluated the effectiveness of a Structured Respiratory Physical Therapy Protocol &#40;SRPP&#41; by means of immediate evaluation by pulmonary ultrasonography compared to a control group aimed at airway clearance and pulmonary re-expansion of atelectasis areas&#46;</p><p id="para0054" class="elsevierStylePara elsevierViewall">This is not the first study to report the use of physiotherapist-applied non-invasive interventions to treat pulmonary atelectasis in children on IMV&#46; However&#44; this is the first study to develop and evaluate an SRPP for the resolution of unilateral pulmonary atelectasis in children&#46;</p><p id="para0055" class="elsevierStylePara elsevierViewall">In both intervention and control groups&#44; the most frequent location of pulmonary atelectasis was the right upper lobe&#44; which has been described previously&#46;<a class="elsevierStyleCrossRefs" href="#bib0015"><span class="elsevierStyleSup">15&#44;16</span></a> This finding can be explained anatomically by the fact that the right upper lobe bronchus is at a 90-degree angle from the right main bronchus&#44; limiting secretion drainage&#46;<a class="elsevierStyleCrossRef" href="#bib0032"><span class="elsevierStyleSup">33</span></a></p><p id="para0056" class="elsevierStylePara elsevierViewall">As described in the study by Galvis et al&#46;&#44;<a class="elsevierStyleCrossRef" href="#bib0014"><span class="elsevierStyleSup">14</span></a> the factors that may have contributed to the development of atelectasis in these patients in addition to the anatomical and physiological features typical of the pediatric age group include factors related to the health status and critical care modalities&#46; These may include alteration of mucociliary transport&#44; resulting from the artificial airway&#44; mucosal edema and&#47;or excessive mucus production due to trauma associated with repeated suctioning&#59; thickening of mucus caused by the disease process&#44; fluid restriction and diuretic use&#59; accumulation of secretions resulting from inadequate bronchial drainage&#44; particularly in children receiving excessive sedation and neuromuscular blockade&#59; inadequate humidification of inspired gas and incomplete removal of tracheal secretions during tracheal aspiration&#46;<a class="elsevierStyleCrossRef" href="#bib0033"><span class="elsevierStyleSup">34</span></a></p><p id="para0057" class="elsevierStylePara elsevierViewall">Previous studies<a class="elsevierStyleCrossRefs" href="#bib0014"><span class="elsevierStyleSup">14&#8211;17</span></a> on this topic have used chest X-Rays as the primary tool to evaluate the resolution of pulmonary atelectasis and the efficacy of treatments&#46; By offering diagnostic accuracy similar to chest radiography&#44; without exposure to ionizing radiation&#44; POCLUS is a dynamic and agile tool to perform and interpret lung changes&#44; quickly integrating the information into the patient&#39;s clinical context&#46;<a class="elsevierStyleCrossRef" href="#bib0034"><span class="elsevierStyleSup">35</span></a> Ultrasound was successfully used in this study to evaluate the outcome of respiratory physiotherapy interventions performed in children on IMV with pulmonary atelectasis&#44; which was detected in the first evaluation by means of radiological imaging&#44; evaluated by the intensive care physician&#46;</p><p id="para0058" class="elsevierStylePara elsevierViewall">Bedside lung ultrasound is a diagnostic tool that has been increasingly used in Intensive Care Units &#40;ICU&#41;&#44; because it is a safe test for both the patient and the team&#44; and can be performed frequently at the bedside by adequately trained PICU professionals&#44; including physiotherapists&#44; allowing non-invasive monitoring of progression and response to therapeutic interventions accurately&#44; quickly&#44; safely and dynamically&#46;<a class="elsevierStyleCrossRef" href="#bib0034"><span class="elsevierStyleSup">35</span></a> Although the authors cannot comment on the sensitivity&#44; specificity or reliability of POCLUS in this context&#44; as post-intervention images were not compared with chest X-Ray findings&#44; owing to ethical and resource limitations&#44; and between-rater comparison was not made&#44; previous studies have reported that lung ultrasound is highly reliable both sensitive and specific in identifying and quantifying pathological changes&#44; including atelectasis&#46;<a class="elsevierStyleCrossRefs" href="#bib0012"><span class="elsevierStyleSup">12&#44;21</span></a> Although further studies are needed&#44; this study supports the feasible and potential utility of using POCLUS to determine short-term responses to chest physiotherapy interventions&#46;</p><p id="para0059" class="elsevierStylePara elsevierViewall">In addition to the evaluation&#44; the LUS<a class="elsevierStyleCrossRef" href="#bib0023"><span class="elsevierStyleSup">24</span></a> was used to quantitatively classify the POCLUS image before and after respiratory physiotherapy interventions in both groups&#46; Adult and neonatal clinical practice experts have suggested that clinical evaluation plus semi-quantification of ultrasound scores can be used as a tool to quantify peripheral lung aeration and clinical severity of the patient&#46;<a class="elsevierStyleCrossRef" href="#bib0035"><span class="elsevierStyleSup">36</span></a> This approach is based on the hypothesis that the lower the peripheral lung expansibility &#40;areas visualized by the POCLUS&#41;&#44; the fewer lung areas will be available for gas exchange&#46;<a class="elsevierStyleCrossRef" href="#bib0036"><span class="elsevierStyleSup">37</span></a> Therefore&#44; it is expected that the clinical manifestations of these pulmonary alterations will be more severe&#46;</p><p id="para0060" class="elsevierStylePara elsevierViewall">Faced with this hypothesis&#44; a retrospective study&#44;<a class="elsevierStyleCrossRef" href="#bib0036"><span class="elsevierStyleSup">37</span></a> including 74 children from zero to 12 months of age&#44; diagnosed with bronchiolitis&#44; and admitted to PICUs&#44; developed a simple and rapid score that combines clinical data &#40;presence of wheezing and reduced oral intake&#41; and ultrasound data &#40;involvement of the right posterior upper pulmonary zone&#41; to predict&#44; during the first evaluation&#44; the need for hospitalization in the PICU&#44; as well as the indication of ventilatory support with CPAP &#40;continuous airway pressure&#41;&#46;</p><p id="para0061" class="elsevierStylePara elsevierViewall">However&#44; one of the limitations of the study was the absence of patients on IMV&#46;</p><p id="para0062" class="elsevierStylePara elsevierViewall">In the present study&#44; although there were large within-group effect sizes&#44; no significant between-group differences were observed in the clinical &#40;WD&#41;<a class="elsevierStyleCrossRef" href="#bib0024"><span class="elsevierStyleSup">25</span></a> or Ultrasonographic &#40;LUS&#41;<a class="elsevierStyleCrossRef" href="#bib0023"><span class="elsevierStyleSup">24</span></a> scores before versus after respiratory physiotherapy intervention&#46; This suggests that both IG and CG interventions were associated with an improvement in pulmonary imaging &#40;partial or total resolution of pulmonary atelectasis&#41; and in the children&#39;s breathing patterns&#46; The magnitude of the treatment effect was&#44; however&#44; greater in the intervention group&#44; suggesting that the protocolized intervention may be more effective at resolving atelectasis in mechanically ventilated children&#46; This requires confirmation in a larger sample study&#46;</p><p id="para0063" class="elsevierStylePara elsevierViewall">The application of mechanical thoracic vibration in the IG may have been one of the factors related to the better findings in the reduction of WD and LUS scores in this group&#46; The natural frequency of ciliary beats in mammals is 13 Hz&#44; an increase in bronchial clearance is observed when vibrations reach frequencies between 11 and 15 Hz&#46;<a class="elsevierStyleCrossRef" href="#bib0037"><span class="elsevierStyleSup">38</span></a> In the range between 20 and 45 Hz&#44; vibration produces relaxation of the respiratory muscles&#44; verified by a decrease in respiratory rate and an increase in tidal volume&#46;<a class="elsevierStyleCrossRef" href="#bib0037"><span class="elsevierStyleSup">38</span></a> The mechanical vibration apparatus used in the study provides a continuous frequency of 50 Hz and&#44; therefore&#44; may have been one of the factors related to the better findings in the intervention group&#46; Bilan et al&#46;<a class="elsevierStyleCrossRef" href="#bib0015"><span class="elsevierStyleSup">15</span></a> used mechanical vibration in some patients in their study for 10 to 20 minutes&#44; and there was no comparison between the interventions or the description of the frequency in Hz used&#46;</p><p id="para0064" class="elsevierStylePara elsevierViewall">Another intervention included in the SRPP&#44; which may have influenced the resolution of pulmonary atelectasis&#44; is the stretching of the accessory respiratory muscles&#46; The stretching of a muscle fiber promotes an increase in the number of sarcomeres in series&#46; The addition of muscle strength due to stretching is possibly due to the better interaction between actin and myosin filaments&#46;<a class="elsevierStyleCrossRef" href="#bib0038"><span class="elsevierStyleSup">39</span></a> Thus&#44; the stretching of the respiratory muscles may have helped in the better performance of the inspiratory and expiratory muscles and increased thoracic expansion and may have contributed to the improvement of respiratory mechanics and to an increase in lung volumes&#46;</p><p id="para0065" class="elsevierStylePara elsevierViewall">Another intervention included in the SRPP&#44; which may have contributed to better results in the intervention group&#44; is manual hyperinflation with a self-inflating bag performed in a standardized manner&#46; Regarding the form of MH application&#44; only one study<a class="elsevierStyleCrossRef" href="#bib40"><span class="elsevierStyleSup">17</span></a> explained how the intervention was applied &#40;first&#44; slow insufflation&#44; followed by an inspiratory pause of two to three seconds&#44; followed by rapid pressure release&#41;&#44; and was performed in the same way in the present study&#44; with the objective of promoting an increase in Peak Expiratory Flow &#40;PEF&#41;&#44; displacing secretion to the central airways and simulating the effect of coughing&#46;<a class="elsevierStyleCrossRef" href="#bib0028"><span class="elsevierStyleSup">29</span></a><span class="elsevierStyleSup">&#44;</span><a class="elsevierStyleCrossRef" href="#bib0039"><span class="elsevierStyleSup">40</span></a> As a safety measure to avoid baro and volutrauma&#44; both the present study and the studies by Galvis et al&#46;<a class="elsevierStyleCrossRef" href="#bib0014"><span class="elsevierStyleSup">14</span></a> and Herrada et al&#46;<a class="elsevierStyleCrossRef" href="#bib40"><span class="elsevierStyleSup">17</span></a> used a manometer during MH to limit Peak Inspiratory Pressure &#40;PIP&#41; between 30&#8210;35 cm H<span class="elsevierStyleInf">2</span>O&#46;</p><p id="para0066" class="elsevierStylePara elsevierViewall">Regarding the safety of the interventions proposed by the SRPP&#44; vital signs are important&#44; as they allow the rapid identification of clinical deterioration of patients before&#44; during&#44; or after physiotherapy interventions&#46;<a class="elsevierStyleCrossRef" href="#bib0028"><span class="elsevierStyleSup">29</span></a> In the present study&#44; vital signs in both groups were statistically similar before and after respiratory physiotherapy&#46; It was not necessary to interrupt the interventions in any of the groups&#44; demonstrating that they do not cause risks of clinical deterioration &#40;bradycardia or tachycardia&#44; tachypnea&#44; drop in SpO<span class="elsevierStyleInf">2</span> or changes in blood pressure&#41; to the patients included in the study&#44; being safe in this context&#46; The retrospective study by Herrada et al&#46;<a class="elsevierStyleCrossRef" href="#bib40"><span class="elsevierStyleSup">17</span></a> also reported that the respiratory physiotherapy interventions were well tolerated and that although all patients presented with tachycardia after the interventions&#44; none of them presented with significant hemodynamic consequences that required medical intervention&#46;</p><p id="para0067" class="elsevierStylePara elsevierViewall">Among the limitations of this study are&#58; a&#41; The SRPP was performed only once&#44; and the patient was not followed up after 30 minutes&#46; Therefore&#44; it was not possible to evaluate maintenance of any clinical or ultrasound improvements&#44; nor the impact on meaningful clinical outcomes such as duration of IMV or PICU length of stay&#59; b&#41; The US findings were not compared to chest X-Ray&#44; so you cannot comment on sensitivity or specify or the tool in this context&#59; c&#41; Variables with several sub-variables did not allow comparison due to the number of cases&#59; d&#41; Due to COVID-19&#44; one of the PICUs in the institution where the study took place was closed&#44; due to the low demand of pediatric patients during this period&#44; making it possible to reach the planned sample size of the study&#44; but over a longer period of data collection&#46;</p><p id="para0068" class="elsevierStylePara elsevierViewall">There are still challenges to be faced for the implementation of POCLUS in the routine of physical therapists&#44; such as the provision of skills training&#44; mentoring&#44; and support from experienced mentors&#46; It is a tool that can optimize the functional diagnosis made by the physiotherapist&#44; as well as guide the interventions that may be proposed&#46; Further research is needed to identify the impact of the inclusion of ultrasound in the clinical decision-making of physiotherapists&#46;</p><p id="para0069" class="elsevierStylePara elsevierViewall">It is suggested that SRPP be applied to larger samples and with longitudinal follow-up to confirm its benefits in the medium and long term&#44; as well as to compare component interventions to identify which one has the greatest impact on the resolution of pulmonary atelectasis in children on IMV&#46;</p></span><span id="sec0017" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="cesectitle0020">Conclusion</span><p id="para0070" class="elsevierStylePara elsevierViewall">This study has shown that the Structured Respiratory Physical Therapy Protocol appears to be safe and may be effective in improving airway clearance and lung re-expansion in children on IMV with unilateral pulmonary atelectasis&#46;</p></span></span>"
    "textoCompletoSecciones" => array:1 [
      "secciones" => array:9 [
        0 => array:3 [
          "identificador" => "xres2273470"
          "titulo" => "Highlights"
          "secciones" => array:1 [
            0 => array:1 [
              "identificador" => "abss0001"
            ]
          ]
        ]
        1 => array:3 [
          "identificador" => "xres2273469"
          "titulo" => "Abstract"
          "secciones" => array:1 [
            0 => array:1 [
              "identificador" => "abss0002"
            ]
          ]
        ]
        2 => array:2 [
          "identificador" => "xpalclavsec1894827"
          "titulo" => "Keywords"
        ]
        3 => array:2 [
          "identificador" => "sec0001"
          "titulo" => "Introduction"
        ]
        4 => array:3 [
          "identificador" => "sec0002"
          "titulo" => "Materials and methods"
          "secciones" => array:9 [
            0 => array:2 [
              "identificador" => "sec0003"
              "titulo" => "Study design and population"
            ]
            1 => array:2 [
              "identificador" => "sec0004"
              "titulo" => "Chest X-ray"
            ]
            2 => array:2 [
              "identificador" => "sec0005"
              "titulo" => "Point of care lung ultrasound &#40;POCLUS&#41;"
            ]
            3 => array:2 [
              "identificador" => "sec0006"
              "titulo" => "Monitoring"
            ]
            4 => array:2 [
              "identificador" => "sec0007"
              "titulo" => "Control group"
            ]
            5 => array:2 [
              "identificador" => "sec0008"
              "titulo" => "Intervention group"
            ]
            6 => array:2 [
              "identificador" => "sec0009"
              "titulo" => "Interrupt criteria"
            ]
            7 => array:2 [
              "identificador" => "sec0010"
              "titulo" => "Statistical analysis"
            ]
            8 => array:2 [
              "identificador" => "sec0011"
              "titulo" => "Evaluation of the magnitude of the effect &#40;effect size&#41;"
            ]
          ]
        ]
        5 => array:3 [
          "identificador" => "sec0012"
          "titulo" => "Results"
          "secciones" => array:3 [
            0 => array:2 [
              "identificador" => "sec0013"
              "titulo" => "Evaluation of lung ultrasound score &#40;LUS&#41; and Wood-Downes &#40;WD&#41; scores"
            ]
            1 => array:2 [
              "identificador" => "sec0014"
              "titulo" => "Assessment of the magnitude of the effect"
            ]
            2 => array:2 [
              "identificador" => "sec0015"
              "titulo" => "Evaluation of effects on physiological parameters"
            ]
          ]
        ]
        6 => array:2 [
          "identificador" => "sec0016"
          "titulo" => "Discussion"
        ]
        7 => array:2 [
          "identificador" => "sec0017"
          "titulo" => "Conclusion"
        ]
        8 => array:1 [
          "titulo" => "References"
        ]
      ]
    ]
    "pdfFichero" => "main.pdf"
    "tienePdf" => true
    "fechaRecibido" => "2023-11-22"
    "fechaAceptado" => "2024-08-25"
    "PalabrasClave" => array:1 [
      "en" => array:1 [
        0 => array:4 [
          "clase" => "keyword"
          "titulo" => "Keywords"
          "identificador" => "xpalclavsec1894827"
          "palabras" => array:5 [
            0 => "Pediatrics"
            1 => "Respiratory physiotherapy"
            2 => "Pulmonary atelectasis"
            3 => "Ultrasound"
            4 => "Mechanical ventilation"
          ]
        ]
      ]
    ]
    "tieneResumen" => true
    "highlights" => array:2 [
      "titulo" => "Highlights"
      "resumen" => "<span id="abss0001" class="elsevierStyleSection elsevierViewall"><p id="spara021" class="elsevierStyleSimplePara elsevierViewall"><ul class="elsevierStyleList" id="celist0001"><li class="elsevierStyleListItem" id="celistitem0001"><p id="para0001" class="elsevierStylePara elsevierViewall"><ul class="elsevierStyleList" id="celist0002"><li class="elsevierStyleListItem" id="celistitem0002"><span class="elsevierStyleLabel">&#8226;</span><p id="para0002" class="elsevierStylePara elsevierViewall">Children are at higher risk of developing atelectasis&#46;</p></li><li class="elsevierStyleListItem" id="celistitem0003"><span class="elsevierStyleLabel">&#8226;</span><p id="para0003" class="elsevierStylePara elsevierViewall">Imaging studies have increased specificity in the diagnosis of atelectasis&#46;</p></li><li class="elsevierStyleListItem" id="celistitem0004"><span class="elsevierStyleLabel">&#8226;</span><p id="para0004" class="elsevierStylePara elsevierViewall">The use of an ultrasound score can quantify pulmonary aeration&#46;</p></li></ul></p></li></ul></p></span>"
    ]
    "resumen" => array:1 [
      "en" => array:2 [
        "titulo" => "Abstract"
        "resumen" => "<span id="abss0002" class="elsevierStyleSection elsevierViewall"><p id="spara022" class="elsevierStyleSimplePara elsevierViewall">Children are at higher risk of atelectasis due to their anatomical and physiological particularities&#46; Several physiotherapy techniques are used to treat atelectasis&#44; but only four studies cite methods in pediatric patients undergoing Invasive Mechanical Ventilation &#40;IMV&#41;&#46; The objective of this study was to evaluate the Structured Respiratory Physiotherapy Protocol &#40;SRPP&#41; for airway clearance and lung reexpansion for infants on IMV with atelectasis&#46; This is a prospective study including 30 infants &#40;mean &#177; standard deviation age 8&#46;9 &#177; 8&#46;0 months&#59; weight 7&#46;5 &#177; 3&#46;0 kg&#59; BMI 15&#46;8 &#177; 1&#46;6 kg&#47;cm<span class="elsevierStyleSup">2</span> and IMV duration 7&#46;7 &#177; 4&#46;3 days&#41;&#46; The sample was randomized into a Control Group &#40;CG&#41;&#44; which received routine physiotherapy&#44; and an Intervention Group &#40;IG&#41;&#44; submitted to SRPP &#40;postural drainage&#44; mechanical thoracic vibration&#44; manual hyperinflation&#44; stretching of the accessory respiratory muscles&#44; and functional positioning&#41;&#46; Both groups were evaluated before and after physiotherapy for respiratory effort using the Wood Downes Score &#40;WD&#41; and pulmonary aeration using lung ultrasonography &#40;Lung Ultrasound Score &#8210; LUS&#41;&#46; The outcome of the intervention was evaluated by the magnitude of the effect by the Hedges&#39; g test &#91;&#40;small &#40;0&#46;2 &#60; Hedges&#39; g &#60; 0&#46;5&#41;&#44; moderate &#40;0&#46;5 &#60; Hedges&#39; g &#60; 0&#46;8&#41; and large &#40;Hedges&#39; g &#62; 0&#46;8&#41; effects&#93;&#46; There were large within-group effects on the reduction of WD in the CG after intervention in both the CG &#40;Hedges&#39; g &#61; -1&#46;53&#41; and IG &#40;Hedges&#39; g &#61; -2&#46;2&#41;&#46; There was a moderate effect on LUS reduction in the CG &#40;Hedges&#39; g &#61; -0&#46;64&#41; and a large effect on IG &#40;Hedges&#39; g &#61; -1&#46;88&#41;&#46; This study has shown that the SRPP appears to be safe and may be effective in improving airway clearance and lung reexpansion in children on IMV with atelectasis&#46;</p></span>"
      ]
    ]
    "multimedia" => array:9 [
      0 => array:8 [
        "identificador" => "fig0001"
        "etiqueta" => "Fig&#46; 1"
        "tipo" => "MULTIMEDIAFIGURA"
        "mostrarFloat" => true
        "mostrarDisplay" => false
        "figura" => array:1 [
          0 => array:4 [
            "imagen" => "gr1.jpeg"
            "Alto" => 2863
            "Ancho" => 2167
            "Tamanyo" => 179710
          ]
        ]
        "detalles" => array:1 [
          0 => array:3 [
            "identificador" => "alt0005"
            "detalle" => "Fig "
            "rol" => "short"
          ]
        ]
        "descripcion" => array:1 [
          "en" => "<p id="spara001" class="elsevierStyleSimplePara elsevierViewall">Description of patient selection&#46; Note&#58; ICU&#44; Intensive Care Unit&#59; IMV&#44; Invasive Mechanical Ventilation&#46;</p>"
        ]
      ]
      1 => array:8 [
        "identificador" => "fig0002"
        "etiqueta" => "Fig&#46; 2"
        "tipo" => "MULTIMEDIAFIGURA"
        "mostrarFloat" => true
        "mostrarDisplay" => false
        "figura" => array:1 [
          0 => array:4 [
            "imagen" => "gr2.jpeg"
            "Alto" => 747
            "Ancho" => 2833
            "Tamanyo" => 358378
          ]
        ]
        "detalles" => array:1 [
          0 => array:3 [
            "identificador" => "alt0006"
            "detalle" => "Fig "
            "rol" => "short"
          ]
        ]
        "descripcion" => array:1 [
          "en" => "<p id="spara002" class="elsevierStyleSimplePara elsevierViewall">Positioning for stretching the respiratory muscles&#58; &#40;A&#41; Upper trapezius&#59; &#40;B&#41; Sternocleidomastoid&#59; &#40;C&#41; Pectoralis major and &#40;D&#41; Intercostals&#46; Source&#58; The author &#40;2023&#41;&#46;</p>"
        ]
      ]
      2 => array:8 [
        "identificador" => "fig0003"
        "etiqueta" => "Fig&#46; 3"
        "tipo" => "MULTIMEDIAFIGURA"
        "mostrarFloat" => true
        "mostrarDisplay" => false
        "figura" => array:1 [
          0 => array:4 [
            "imagen" => "gr3.jpeg"
            "Alto" => 2967
            "Ancho" => 2833
            "Tamanyo" => 204203
          ]
        ]
        "detalles" => array:1 [
          0 => array:3 [
            "identificador" => "alt0007"
            "detalle" => "Fig "
            "rol" => "short"
          ]
        ]
        "descripcion" => array:1 [
          "en" => "<p id="spara003" class="elsevierStyleSimplePara elsevierViewall">Sample selection flowchart&#46;</p>"
        ]
      ]
      3 => array:8 [
        "identificador" => "fig0004"
        "etiqueta" => "Fig&#46; 4"
        "tipo" => "MULTIMEDIAFIGURA"
        "mostrarFloat" => true
        "mostrarDisplay" => false
        "figura" => array:1 [
          0 => array:4 [
            "imagen" => "gr4.jpeg"
            "Alto" => 1349
            "Ancho" => 3167
            "Tamanyo" => 142183
          ]
        ]
        "detalles" => array:1 [
          0 => array:3 [
            "identificador" => "alt0008"
            "detalle" => "Fig "
            "rol" => "short"
          ]
        ]
        "descripcion" => array:1 [
          "en" => "<p id="spara004" class="elsevierStyleSimplePara elsevierViewall">Magnitude of the effect &#40;effect size&#41; of the intervention proposed in the study &#40;GI&#41; on LUS &#40;y axis&#41;&#44; compared to the effect of routine physiotherapy &#40;CG&#41;&#44; shown by the differences between the medians &#40;green bars&#41; and the values &#8220;g&#8221; for Hedges&#46;</p>"
        ]
      ]
      4 => array:8 [
        "identificador" => "fig0005"
        "etiqueta" => "Fig&#46; 5"
        "tipo" => "MULTIMEDIAFIGURA"
        "mostrarFloat" => true
        "mostrarDisplay" => false
        "figura" => array:1 [
          0 => array:4 [
            "imagen" => "gr5.jpeg"
            "Alto" => 1267
            "Ancho" => 3167
            "Tamanyo" => 146115
          ]
        ]
        "detalles" => array:1 [
          0 => array:3 [
            "identificador" => "alt0009"
            "detalle" => "Fig "
            "rol" => "short"
          ]
        ]
        "descripcion" => array:1 [
          "en" => "<p id="spara005" class="elsevierStyleSimplePara elsevierViewall">Magnitude of the effect &#40;effect size&#41; of the intervention proposed in the study &#40;GI&#41; on the Wood-Downes score &#40;y-axis&#41;&#44; compared to the effect of routine physiotherapy &#40;CG&#41;&#44; shown by the differences between the medians &#40;green bars&#41; and by Hedges&#8217; &#8220;g&#8221; values&#46;</p>"
        ]
      ]
      5 => array:8 [
        "identificador" => "tbl0001"
        "etiqueta" => "Table 1"
        "tipo" => "MULTIMEDIATABLA"
        "mostrarFloat" => true
        "mostrarDisplay" => false
        "detalles" => array:1 [
          0 => array:3 [
            "identificador" => "alt0001"
            "detalle" => "Table "
            "rol" => "short"
          ]
        ]
        "tabla" => array:2 [
          "leyenda" => "<p id="spara007" class="elsevierStyleSimplePara elsevierViewall">NOTE&#58; <span class="elsevierStyleSup">a</span> Median &#40;IIQ 25&#37;&#8210;75&#37;&#41;&#59; <span class="elsevierStyleSup">b</span> Mean &#177; Standard Deviation&#59; <span class="elsevierStyleSup">c</span> Variables with multiple subvariables did not allow generating statistical significance due to the number of cases&#46;</p><p id="spara008" class="elsevierStyleSimplePara elsevierViewall">p&#42;&#44; p-values by the Wilcoxon&#47;Mann-Whitney test or Fisher&#39;s exact test&#44; when applicable&#59; N&#44; Absolute number&#59; Kg&#44; Kilogram&#59; cm&#44; Centimeters&#59; BMI&#44; Body Mass Index&#59; PIM2&#44; Pediatric Index of Mortality 2&#59; IMV&#44; Invasive Mechanical Ventilation&#59; ICU&#44; Intensive Care Unit&#44; pH&#44; Hydrogen Potential&#59; PaO<span class="elsevierStyleInf">2</span>&#44; Partial Pressure of Oxygen&#59; PaCO<span class="elsevierStyleInf">2</span>&#44; Partial Pressure of Carbon Dioxide&#59; BE&#44; Base Excess&#59; SaO<span class="elsevierStyleInf">2</span>&#44; Arterial Oxygen Saturation&#59; PaO<span class="elsevierStyleInf">2</span>&#47;FiO<span class="elsevierStyleInf">2</span>&#44; Ratio of Partial Pressure of Oxygen to the fraction of inspired oxygen&#59; Hb&#44; Hemoglobin&#59; Ht&#44; Hematocrit&#59; CRP&#44; C-Reactive Protein&#59; RSV&#44; Respiratory Syncytial Virus&#46;</p>"
          "tablatextoimagen" => array:1 [
            0 => array:2 [
              "tabla" => array:1 [
                0 => """
                  <table border="0" frame="\n
                  \t\t\t\t\tvoid\n
                  \t\t\t\t" class=""><thead title="thead"><tr title="table-row"><a name="en0001"></a><th class="td" title="\n
                  \t\t\t\t\ttable-head\n
                  \t\t\t\t  " align="" valign="top" scope="col">Variables&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t\t\t</th><a name="en0002"></a><th class="td-with-role" title="\n
                  \t\t\t\t\ttable-head\n
                  \t\t\t\t ; entry_with_role_colgroup " colspan="2" align="left" valign="top" scope="col">Group Control</th><a name="en0003"></a><th class="td-with-role" title="\n
                  \t\t\t\t\ttable-head\n
                  \t\t\t\t ; entry_with_role_colgroup " colspan="2" align="left" valign="top" scope="col">Group Intervention</th><a name="en0004"></a><th class="td" title="\n
                  \t\t\t\t\ttable-head\n
                  \t\t\t\t  " align="" valign="top" scope="col">p&#42;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t\t\t</th></tr><tr title="table-row"><a name="en0005"></a><th class="td" title="\n
                  \t\t\t\t\ttable-head\n
                  \t\t\t\t  " align="" valign="top" scope="col" style="border-bottom: 2px solid black">N&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t\t\t</th><a name="en0006"></a><th class="td-with-role" title="\n
                  \t\t\t\t\ttable-head\n
                  \t\t\t\t ; entry_with_role_colgroup " colspan="2" align="left" valign="top" scope="col" style="border-bottom: 2px solid black">15</th><a name="en0007"></a><th class="td-with-role" title="\n
                  \t\t\t\t\ttable-head\n
                  \t\t\t\t ; entry_with_role_colgroup " colspan="2" align="left" valign="top" scope="col" style="border-bottom: 2px solid black">15</th><a name="en0008"></a><th class="td" title="\n
                  \t\t\t\t\ttable-head\n
                  \t\t\t\t  " align="" valign="top" scope="col" style="border-bottom: 2px solid black">&#8210;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t\t\t</th></tr></thead><tbody title="tbody"><tr title="table-row"><a name="en0009"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">Female gender&#44; n &#40;&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0010"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">6&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0011"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">40&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0012"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">4&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0013"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">26&#46;7&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0014"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">0&#46;6&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><a name="en0015"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">Age &#40;months&#41;<span class="elsevierStyleSup">a</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0016"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">7&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0017"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">2&#46;0&#8210;17&#46;0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0018"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">4&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0019"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">2&#46;0&#8210;13&#46;5&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0020"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">0&#46;7&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><a name="en0021"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">Diagnostics&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0022"></a><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_colgroup " colspan="5" align="left" valign="top"></td></tr><tr title="table-row"><a name="en0023"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">Viral bronchiolitis&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0024"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">11&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0025"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">73&#46;3&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0026"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">11&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0027"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">73&#46;3&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0028"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top"><span class="elsevierStyleSup">c</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><a name="en0029"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">Pneumonia&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0030"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">&#8210;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0031"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">&#8210;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0032"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">1&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0033"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">6&#46;7&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0034"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top"><span class="elsevierStyleSup">c</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><a name="en0035"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">Nephrotic syndrome&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0036"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">&#8210;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0037"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">&#8210;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0038"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">1&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0039"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">6&#46;7&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0040"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top"><span class="elsevierStyleSup">c</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><a name="en0041"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">Septic shock&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0042"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">3&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0043"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">20&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0044"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">2&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0045"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">13&#46;3&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0046"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top"><span class="elsevierStyleSup">c</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><a name="en0047"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">Wheezing crisis&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0048"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">1&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0049"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">6&#46;7&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0050"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">&#8210;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0051"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">&#8210;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0052"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top"><span class="elsevierStyleSup">c</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><a name="en0053"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">Weight &#40;Kg&#41;<span class="elsevierStyleSup">b</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0054"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">7&#46;7&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0055"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">3&#46;2&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0056"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">7&#46;4&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0057"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">2&#46;9&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0058"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">0&#46;4&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><a name="en0059"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">Height &#40;cm&#41;<span class="elsevierStyleSup">b</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0060"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">68&#46;3&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0061"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">12&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0062"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">67&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0063"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">12&#46;6&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0064"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">0&#46;7&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><a name="en0065"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">BMI &#40;Kg&#47;cm<span class="elsevierStyleSup">2</span>&#41;<span class="elsevierStyleSup">b</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0066"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">15&#46;5&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0067"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">1&#46;7&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0068"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">16&#46;2&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0069"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">1&#46;6&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0070"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">0&#46;4&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><a name="en0071"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">PIM2<span class="elsevierStyleSup">b</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0072"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">5&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0073"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">7&#46;5&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0074"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">2&#46;1&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0075"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">1&#46;3&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0076"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">0&#46;6&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><a name="en0077"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">Duration of IMV &#40;days&#41;<span class="elsevierStyleSup">a</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0078"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">7&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0079"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">5&#46;5&#8210;8&#46;5&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0080"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">6&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0081"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">4&#46;5&#8210;8&#46;5&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0082"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">0&#46;5&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><a name="en0083"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">ICU length of stay &#40;days&#41;<span class="elsevierStyleSup">a</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0084"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">15&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0085"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">11&#46;0&#8210;16&#46;0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0086"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">12&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0087"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">9&#46;5&#8210;18&#46;5&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0088"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">0&#46;4&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><a name="en0089"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">Hospital length of stay &#40;days&#41;<span class="elsevierStyleSup">a</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0090"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">19&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0091"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">17&#46;0&#8210;24&#46;0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0092"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">21&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0093"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">12&#46;5&#8210;24&#46;5&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0094"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">0&#46;6&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><a name="en0095"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">pH<span class="elsevierStyleSup">a</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0096"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">7&#46;4&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0097"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">0&#46;1&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0098"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">7&#46;4&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0099"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">0&#46;1&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0100"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">0&#46;3&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><a name="en0101"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">PaO<span class="elsevierStyleInf">2</span><span class="elsevierStyleSup">a</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0102"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">91&#46;5&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0103"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">40&#46;3&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0104"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">108&#46;7&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0105"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">37&#46;8&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0106"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">0&#46;3&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><a name="en0107"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">PaCO<span class="elsevierStyleInf">2</span><span class="elsevierStyleSup">a</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0108"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">46&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0109"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">10&#46;7&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0110"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">46&#46;3&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0111"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">14&#46;1&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0112"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">0&#46;8&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><a name="en0113"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">HCO<span class="elsevierStyleInf">3</span><span class="elsevierStyleSup">a</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0114"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">29&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0115"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">7&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0116"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">26&#46;7&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0117"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">5&#46;2&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0118"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">0&#46;2&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><a name="en0119"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">BE<span class="elsevierStyleSup">a</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0120"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">3&#46;8&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0121"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">7&#46;3&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0122"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">1&#46;1&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0123"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">4&#46;9&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0124"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">0&#46;1&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><a name="en0125"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">SaO<span class="elsevierStyleInf">2</span><span class="elsevierStyleSup">a</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0126"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">93&#46;1&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0127"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">8&#46;3&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0128"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">96&#46;3&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0129"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">4&#46;5&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0130"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">0&#46;5&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><a name="en0131"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">PaO<span class="elsevierStyleInf">2</span>&#47;FiO<span class="elsevierStyleInf">2</span><span class="elsevierStyleSup">a</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0132"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">256&#46;9&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0133"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">171&#46;4&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0134"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">299&#46;7&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0135"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">106&#46;6&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0136"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">0&#46;3&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><a name="en0137"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">Hb<span class="elsevierStyleSup">a</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0138"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">10&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0139"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">1&#46;4&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0140"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">9&#46;7&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0141"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">1&#46;5&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0142"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">0&#46;3&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><a name="en0143"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">Ht<span class="elsevierStyleSup">a</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0144"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">30&#46;2&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0145"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">4&#46;2&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0146"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">27&#46;6&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0147"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">4&#46;5&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0148"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">0&#46;07&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><a name="en0149"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">Platelets<span class="elsevierStyleSup">a</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0150"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">326533&#46;3&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0151"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">143116&#46;8&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0152"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">316000&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0153"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">134982&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0154"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">0&#46;6&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><a name="en0155"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">Lactate<span class="elsevierStyleSup">a</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0156"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">1&#46;8&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0157"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">1&#46;6&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0158"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">1&#46;6&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0159"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">1&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0160"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">0&#46;9&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><a name="en0161"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">CRP<span class="elsevierStyleSup">a</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0162"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">3&#46;5&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0163"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">2&#46;9&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0164"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">5&#46;7&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0165"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">5&#46;5&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0166"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">0&#46;4&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><a name="en0167"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">Viral panel&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0168"></a><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_colgroup " colspan="5" align="left" valign="top"></td></tr><tr title="table-row"><a name="en0169"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">RSV&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0170"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">9&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0171"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">81&#46;8&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0172"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">8&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0173"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">72&#46;7&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0174"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top"><span class="elsevierStyleSup">c</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><a name="en0175"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">Bocavirus&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0176"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">2&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0177"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">18&#46;2&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0178"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">&#8210;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0179"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">&#8210;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0180"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top"><span class="elsevierStyleSup">c</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><a name="en0181"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">Parainfluenza I e II&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0182"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">&#8210;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0183"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">&#8210;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0184"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">1&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0185"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">9&#46;1&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0186"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top"><span class="elsevierStyleSup">c</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><a name="en0187"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">Metapnemovirus&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0188"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">&#8210;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0189"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">&#8210;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0190"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">1&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0191"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">9&#46;1&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0192"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top"><span class="elsevierStyleSup">c</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><a name="en0193"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">Seasonal coronavirus&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0194"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">&#8210;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0195"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">&#8210;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0196"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">1&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0197"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">9&#46;1&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0198"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top"><span class="elsevierStyleSup">c</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr></tbody></table>
                  """
              ]
              "imagenFichero" => array:1 [
                0 => "xTab3692114.png"
              ]
            ]
          ]
        ]
        "descripcion" => array:1 [
          "en" => "<p id="spara006" class="elsevierStyleSimplePara elsevierViewall">Epidemiological characteristics&#44; clinical variables and laboratory tests of the sample according to groups and results of statistical tests&#46;</p>"
        ]
      ]
      6 => array:8 [
        "identificador" => "tbl0002"
        "etiqueta" => "Table 2"
        "tipo" => "MULTIMEDIATABLA"
        "mostrarFloat" => true
        "mostrarDisplay" => false
        "detalles" => array:1 [
          0 => array:3 [
            "identificador" => "alt0002"
            "detalle" => "Table "
            "rol" => "short"
          ]
        ]
        "tabla" => array:2 [
          "leyenda" => "<p id="spara010" class="elsevierStyleSimplePara elsevierViewall">Note&#58; <span class="elsevierStyleSup">a</span> Mean and standard deviation&#59; <span class="elsevierStyleSup">b</span> Variables with multiple subvariables did not allow generating statistical significance due to the number of cases&#46;</p><p id="spara011" class="elsevierStyleSimplePara elsevierViewall">p&#42;&#44; p-values by the Wilcoxon&#47;Mann-Whitney test&#46;</p><p id="spara012" class="elsevierStyleSimplePara elsevierViewall">N&#44; Absolute Number&#59; IMV&#44; Invasive Mechanical Ventilation&#59; PCV&#44; Pressure Controlled Ventilation&#59; PSV&#44; Pressure Support Ventilation&#59; PRVC&#44; Pressure-Regulated and Volume-Controlled Ventilation&#59; SIMV&#44; Synchronized Intermittent Mandatory Ventilation&#59; cm H<span class="elsevierStyleInf">2</span>O&#44; Centimeters of Water&#59; PIP&#44; Peak Inspiratory Pressure&#59; PEEP&#44; Positive End-Expiratory Pressure&#59; RR&#44; Respiratory Rate&#59; ipm&#44; Incursions per minute&#59; IT&#44; Inspiratory Time&#59; s&#44; seconds&#59; FiO<span class="elsevierStyleInf">2</span>&#44; Fraction of Inspired Oxygen&#59; MAP&#44; Mean Airway Pressure&#59; TV&#44; Total Volume&#59; mL&#44; Milliliter&#59; VT&#44; Tidal Volume&#59; mL&#47;Kg&#44; Milliliter per kilo&#59; VAP&#44; Ventilator-Associated Pneumonia&#59; Radiological score&#44; Radiological Atelectasis Scoring System&#59; RUL&#44; Right Upper Lobe&#59; RML&#44; Right Middle Lobe&#59; LLL&#44; Left Lower Lobe&#46;</p>"
          "tablatextoimagen" => array:1 [
            0 => array:2 [
              "tabla" => array:1 [
                0 => """
                  <table border="0" frame="\n
                  \t\t\t\t\tvoid\n
                  \t\t\t\t" class=""><thead title="thead"><tr title="table-row"><a name="en0199"></a><th class="td" title="\n
                  \t\t\t\t\ttable-head\n
                  \t\t\t\t  " align="" valign="top" scope="col" style="border-bottom: 2px solid black">Variables&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t\t\t</th><a name="en0200"></a><th class="td-with-role" title="\n
                  \t\t\t\t\ttable-head\n
                  \t\t\t\t ; entry_with_role_colgroup " colspan="2" align="left" valign="top" scope="col" style="border-bottom: 2px solid black">Control group</th><a name="en0201"></a><th class="td-with-role" title="\n
                  \t\t\t\t\ttable-head\n
                  \t\t\t\t ; entry_with_role_colgroup " colspan="2" align="left" valign="top" scope="col" style="border-bottom: 2px solid black">Intervention group</th><a name="en0202"></a><th class="td" title="\n
                  \t\t\t\t\ttable-head\n
                  \t\t\t\t  " align="" valign="top" scope="col" style="border-bottom: 2px solid black">p&#42;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t\t\t</th></tr></thead><tbody title="tbody"><tr title="table-row"><a name="en0203"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">IMV mode&#44; n &#40;&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0204"></a><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_colgroup " colspan="5" align="left" valign="top"></td></tr><tr title="table-row"><a name="en0205"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">PCV &#40;cm H<span class="elsevierStyleInf">2</span>O&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0206"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">11&#46;0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0207"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">73&#46;3&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0208"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">10&#46;0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0209"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">66&#46;6&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0210"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top"><span class="elsevierStyleSup">b</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><a name="en0211"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">PSV &#40;cm H<span class="elsevierStyleInf">2</span>O&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0212"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">1&#46;0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0213"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">6&#46;7&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0214"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">1&#46;0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0215"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">6&#46;7&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0216"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top"><span class="elsevierStyleSup">b</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><a name="en0217"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">PRVC &#40;cm H<span class="elsevierStyleInf">2</span>O&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0218"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">&#8210;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0219"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">&#8210;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0220"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">1&#46;0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0221"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">6&#46;7&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0222"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top"><span class="elsevierStyleSup">b</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><a name="en0223"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">SIMV &#40;cm H<span class="elsevierStyleInf">2</span>O&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0224"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">3&#46;0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0225"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">20&#46;0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0226"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">3&#46;0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0227"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">20&#46;0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0228"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top"><span class="elsevierStyleSup">b</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><a name="en0229"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">Ventilatory parameters<span class="elsevierStyleSup">a</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0230"></a><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_colgroup " colspan="5" align="left" valign="top"></td></tr><tr title="table-row"><a name="en0231"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">PIP &#40;cm H<span class="elsevierStyleInf">2</span>O&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0232"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">21&#46;7&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0233"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">3&#46;0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0234"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">22&#46;1&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0235"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">3&#46;6&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0236"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">0&#46;8&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><a name="en0237"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">PEEP &#40;cm H<span class="elsevierStyleInf">2</span>O&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0238"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">7&#46;0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0239"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">1&#46;0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0240"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">6&#46;8&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0241"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">0&#46;6&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0242"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">0&#46;7&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><a name="en0243"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">RR &#40;ipm&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0244"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">27&#46;3&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0245"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">5&#46;3&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0246"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">25&#46;8&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0247"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">3&#46;8&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0248"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">0&#46;7&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><a name="en0249"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">IT &#40;s&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0250"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">0&#46;6&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0251"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">0&#46;1&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0252"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">0&#46;6&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0253"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">0&#46;1&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0254"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">0&#46;7&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><a name="en0255"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">FiO2 &#40;&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0256"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">44&#46;0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0257"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">18&#46;4&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0258"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">37&#46;8&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0259"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">12&#46;2&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0260"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">0&#46;6&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><a name="en0261"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">MAP &#40;cm H<span class="elsevierStyleInf">2</span>O&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0262"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">11&#46;5&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0263"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">2&#46;0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0264"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">13&#46;0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0265"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">1&#46;9&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0266"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">0&#46;1&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><a name="en0267"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">TV &#40;mL&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0268"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">65&#46;8&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0269"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">36&#46;8&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0270"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">61&#46;3&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0271"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">38&#46;9&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0272"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">0&#46;3&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><a name="en0273"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">VT &#40;mL&#47;Kg&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0274"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">6&#46;0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0275"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">3&#46;0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0276"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">8&#46;0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0277"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">2&#46;5&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0278"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">0&#46;9&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><a name="en0279"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">Intratracheal cuff&#44; n &#40;&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0280"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">6&#46;0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0281"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">40&#46;0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0282"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">6&#46;0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0283"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">40&#46;0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0284"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top"><span class="elsevierStyleSup">b</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><a name="en0285"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">VAP&#44; n &#40;&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0286"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">2&#46;0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0287"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">13&#46;3&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0288"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">1&#46;0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0289"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">6&#46;7&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0290"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top"><span class="elsevierStyleSup">b</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><a name="en0291"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">Radiological score<span class="elsevierStyleSup">a</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0292"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">2&#46;7&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0293"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">0&#46;9&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0294"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">3&#46;1&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0295"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">0&#46;9&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0296"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">0&#46;3&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><a name="en0297"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">Location of atelectasis<span class="elsevierStyleSup">a</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0298"></a><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_colgroup " colspan="5" align="left" valign="top"></td></tr><tr title="table-row"><a name="en0299"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">RUL&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0300"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">9&#46;0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0301"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">60&#46;0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0302"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">11&#46;0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0303"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">73&#46;3&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0304"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top"><span class="elsevierStyleSup">b</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><a name="en0305"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">RML&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0306"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">4&#46;0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0307"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">26&#46;7&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0308"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">4&#46;0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0309"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">26&#46;7&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0310"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top"><span class="elsevierStyleSup">b</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><a name="en0311"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">LLL&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0312"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">2&#46;0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0313"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">13&#46;3&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0314"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">&#8210;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0315"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">&#8210;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0316"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top"><span class="elsevierStyleSup">b</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><a name="en0317"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">Aspirations<span class="elsevierStyleSup">a</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0318"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">1&#46;8&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0319"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">0&#46;8&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0320"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">2&#46;1&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0321"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">0&#46;8&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0322"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">0&#46;4&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><a name="en0323"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">Quality&#44; n &#40;&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0324"></a><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_colgroup " colspan="5" align="left" valign="top"></td></tr><tr title="table-row"><a name="en0325"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">Moderate&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0326"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">14&#46;0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0327"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">93&#46;3&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0328"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">15&#46;0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0329"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">100&#46;0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0330"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top"><span class="elsevierStyleSup">b</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><a name="en0331"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">Thick&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0332"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">1&#46;0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0333"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">6&#46;7&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0334"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">&#8210;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0335"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">&#8210;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0336"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top"><span class="elsevierStyleSup">b</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><a name="en0337"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">Colour&#44; n &#40;&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0338"></a><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_colgroup " colspan="5" align="left" valign="top"></td></tr><tr title="table-row"><a name="en0339"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">Clear&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0340"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">10&#46;0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0341"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">66&#46;7&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0342"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">10&#46;0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0343"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">66&#46;7&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0344"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top"><span class="elsevierStyleSup">b</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><a name="en0345"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">Yellowish&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0346"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">5&#46;0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0347"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">33&#46;3&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0348"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">5&#46;0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0349"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">33&#46;3&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0350"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top"><span class="elsevierStyleSup">b</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr></tbody></table>
                  """
              ]
              "imagenFichero" => array:1 [
                0 => "xTab3692113.png"
              ]
            ]
          ]
        ]
        "descripcion" => array:1 [
          "en" => "<p id="spara009" class="elsevierStyleSimplePara elsevierViewall">Description of modes&#44; ventilation parameters&#44; incidence of Ventilator-Associated Pneumonia &#40;VAP&#41;&#44; Radiological Atelectasis Scoring System score&#44; location of atelectasis and characteristics of tracheal secretion according to groups and results of statistical tests&#46;</p>"
        ]
      ]
      7 => array:8 [
        "identificador" => "tbl0003"
        "etiqueta" => "Table 3"
        "tipo" => "MULTIMEDIATABLA"
        "mostrarFloat" => true
        "mostrarDisplay" => false
        "detalles" => array:1 [
          0 => array:3 [
            "identificador" => "alt0003"
            "detalle" => "Table "
            "rol" => "short"
          ]
        ]
        "tabla" => array:2 [
          "leyenda" => "<p id="spara014" class="elsevierStyleSimplePara elsevierViewall">Note&#58; P25&#44; 25<span class="elsevierStyleSup">th</span> percentile&#59; P75&#44; 75<span class="elsevierStyleSup">th</span> percentile&#46;</p><p id="spara015" class="elsevierStyleSimplePara elsevierViewall">p&#42;&#44; p-values by the Wilcoxon&#47;Mann-Whitney test&#46;</p><p id="spara016" class="elsevierStyleSimplePara elsevierViewall">LUS&#44; Lung Ultrasound Score&#59; WD&#44; Wood-Downes&#59; CG&#44; Control Group&#59; IG&#44; Intervention Group&#59; Before&#44; Before respiratory physiotherapy&#59; After&#44; After respiratory physiotherapy&#46;</p>"
          "tablatextoimagen" => array:1 [
            0 => array:2 [
              "tabla" => array:1 [
                0 => """
                  <table border="0" frame="\n
                  \t\t\t\t\tvoid\n
                  \t\t\t\t" class=""><thead title="thead"><tr title="table-row"><a name="en0351"></a><th class="td" title="\n
                  \t\t\t\t\ttable-head\n
                  \t\t\t\t  " align="" valign="top" scope="col" style="border-bottom: 2px solid black">Score&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t\t\t</th><a name="en0352"></a><th class="td" title="\n
                  \t\t\t\t\ttable-head\n
                  \t\t\t\t  " align="" valign="top" scope="col" style="border-bottom: 2px solid black">Median&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t\t\t</th><a name="en0353"></a><th class="td" title="\n
                  \t\t\t\t\ttable-head\n
                  \t\t\t\t  " align="" valign="top" scope="col" style="border-bottom: 2px solid black">P 25&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t\t\t</th><a name="en0354"></a><th class="td" title="\n
                  \t\t\t\t\ttable-head\n
                  \t\t\t\t  " align="" valign="top" scope="col" style="border-bottom: 2px solid black">P 75&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t\t\t</th><a name="en0355"></a><th class="td" title="\n
                  \t\t\t\t\ttable-head\n
                  \t\t\t\t  " align="" valign="top" scope="col" style="border-bottom: 2px solid black">p&#42;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t\t\t</th></tr></thead><tbody title="tbody"><tr title="table-row"><a name="en0356"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">LUS CG before&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0357"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">2&#46;0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0358"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">1&#46;0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0359"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">3&#46;0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0360"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">0&#46;01&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><a name="en0361"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">LUS CG after&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0362"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">1&#46;0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0363"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">1&#46;0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0364"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">2&#46;5&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0365"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><a name="en0366"></a><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_colgroup " colspan="5" align="left" valign="top"></td></tr><tr title="table-row"><a name="en0367"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">LUS IG before&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0368"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">3&#46;0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0369"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">2&#46;0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0370"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">3&#46;0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0371"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">&#60;0&#46;001&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><a name="en0372"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">LUS IG after&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0373"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">1&#46;0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0374"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">0&#46;5&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0375"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">2&#46;0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0376"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><a name="en0377"></a><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_colgroup " colspan="5" align="left" valign="top"></td></tr><tr title="table-row"><a name="en0378"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">WD CG before&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0379"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">4&#46;0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0380"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">3&#46;5&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0381"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">5&#46;0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0382"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">&#60;0&#46;001&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><a name="en0383"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">WD CG after&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0384"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">3&#46;0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0385"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">2&#46;0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0386"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">3&#46;0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0387"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><a name="en0388"></a><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_colgroup " colspan="5" align="left" valign="top"></td></tr><tr title="table-row"><a name="en0389"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">WD IG before&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0390"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">4&#46;0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0391"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">3&#46;0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0392"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">5&#46;0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0393"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">&#60;0&#46;001&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><a name="en0394"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">WD IG after&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0395"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">2&#46;0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0396"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">1&#46;0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0397"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">2&#46;5&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0398"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr></tbody></table>
                  """
              ]
              "imagenFichero" => array:1 [
                0 => "xTab3692111.png"
              ]
            ]
          ]
        ]
        "descripcion" => array:1 [
          "en" => "<p id="spara013" class="elsevierStyleSimplePara elsevierViewall">Description of LUS and Wood-Downes Score comparing groups&#44; moments and results of statistical tests&#46;</p>"
        ]
      ]
      8 => array:8 [
        "identificador" => "tbl0004"
        "etiqueta" => "Table 4"
        "tipo" => "MULTIMEDIATABLA"
        "mostrarFloat" => true
        "mostrarDisplay" => false
        "detalles" => array:1 [
          0 => array:3 [
            "identificador" => "alt0004"
            "detalle" => "Table "
            "rol" => "short"
          ]
        ]
        "tabla" => array:2 [
          "leyenda" => "<p id="spara018" class="elsevierStyleSimplePara elsevierViewall">Note&#58; Data are in means and standard deviations&#46;</p><p id="spara019" class="elsevierStyleSimplePara elsevierViewall">p&#42;&#44; p-values according to the non-parametric Friedman test&#44; with post-hoc analysis using the paired Wilcoxon test &#40;signed rank&#41;&#44; with Bonferroni correction&#46;</p><p id="spara020" class="elsevierStyleSimplePara elsevierViewall">Before&#44; Before respiratory physiotherapy&#59; HR&#44; Heart Rate&#59; min&#44; Minutes&#59; RR&#44; Respiratory Rate&#59; Temp&#44; Body Temperature in degrees Celsius&#59; degrees Celsius&#59; SPO<span class="elsevierStyleInf">2</span>&#44; Peripheral Oxygen Saturation&#59; SBP&#44; Systolic Blood Pressure&#59; DBP&#44; Diastolic Blood Pressure&#59; ABP&#44; Average Arterial Pressure&#46;</p>"
          "tablatextoimagen" => array:1 [
            0 => array:2 [
              "tabla" => array:1 [
                0 => """
                  <table border="0" frame="\n
                  \t\t\t\t\tvoid\n
                  \t\t\t\t" class=""><thead title="thead"><tr title="table-row"><a name="en0399"></a><th class="td" title="\n
                  \t\t\t\t\ttable-head\n
                  \t\t\t\t  " align="" valign="top" scope="col" style="border-bottom: 2px solid black">Variables&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t\t\t</th><a name="en0400"></a><th class="td-with-role" title="\n
                  \t\t\t\t\ttable-head\n
                  \t\t\t\t ; entry_with_role_colgroup " colspan="2" align="left" valign="top" scope="col" style="border-bottom: 2px solid black">Group control</th><a name="en0401"></a><th class="td-with-role" title="\n
                  \t\t\t\t\ttable-head\n
                  \t\t\t\t ; entry_with_role_colgroup " colspan="2" align="left" valign="top" scope="col" style="border-bottom: 2px solid black">Group intervention</th><a name="en0402"></a><th class="td" title="\n
                  \t\t\t\t\ttable-head\n
                  \t\t\t\t  " align="" valign="top" scope="col" style="border-bottom: 2px solid black">p&#42;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t\t\t</th></tr></thead><tbody title="tbody"><tr title="table-row"><a name="en0403"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">HR before &#40;bpm&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0404"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">139&#46;9&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0405"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">26&#46;7&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0406"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">142&#46;7&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0407"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">23&#46;3&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0408"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">0&#46;9&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><a name="en0409"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">HR 10 min &#40;bpm&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0410"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">140&#46;9&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0411"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">22&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0412"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">140&#46;5&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0413"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">20&#46;3&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0414"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">0&#46;8&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><a name="en0415"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">HR 30 min &#40;bpm&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0416"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">137&#46;1&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0417"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">23&#46;9&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0418"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">135&#46;9&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0419"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">19&#46;7&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0420"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">0&#46;8&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><a name="en0421"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">RR before &#40;ipm&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0422"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">38&#46;3&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0423"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">11&#46;1&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0424"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">37&#46;4&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0425"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">10&#46;2&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0426"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">0&#46;8&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><a name="en0427"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">RR 10 min &#40;ipm&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0428"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">36&#46;8&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0429"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">8&#46;5&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0430"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">34&#46;7&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0431"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">7&#46;6&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0432"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">0&#46;7&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><a name="en0433"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">RR 30 min &#40;ipm&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0434"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">32&#46;5&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0435"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">7&#46;1&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0436"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">32&#46;3&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0437"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">5&#46;4&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0438"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">0&#46;9&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><a name="en0439"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">Temp&#46; before &#40;&#176;C&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0440"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">36&#46;7&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0441"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">0&#46;5&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0442"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">36&#46;6&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0443"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">0&#46;5&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0444"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">0&#46;7&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><a name="en0445"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">Temp&#46; 10 min &#40;&#176;C&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0446"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">36&#46;6&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0447"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">0&#46;4&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0448"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">36&#46;6&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0449"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">0&#46;5&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0450"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">0&#46;7&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><a name="en0451"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">Temp&#46; 30 min &#40;&#176;C&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0452"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">36&#46;7&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0453"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">0&#46;4&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0454"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">36&#46;6&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0455"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">0&#46;5&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0456"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">0&#46;6&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><a name="en0457"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">SPO<span class="elsevierStyleInf">2</span> before &#40;&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0458"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">95&#46;5&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0459"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">3&#46;4&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0460"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">96&#46;5&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0461"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">4&#46;1&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0462"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">0&#46;4&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><a name="en0463"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">SPO<span class="elsevierStyleInf">2</span> 10 min &#40;&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0464"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">98&#46;2&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0465"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">2&#46;5&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0466"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">98&#46;2&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0467"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">2&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0468"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">0&#46;8&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><a name="en0469"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">SPO<span class="elsevierStyleInf">2</span> 30 min &#40;&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0470"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">97&#46;9&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0471"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">2&#46;4&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0472"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">98&#46;5&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0473"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">2&#46;2&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0474"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">0&#46;5&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><a name="en0475"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">SBP before &#40;mmHg&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0476"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">98&#46;1&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0477"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">17&#46;2&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0478"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">104&#46;3&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0479"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">13&#46;1&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0480"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">0&#46;3&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><a name="en0481"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">SBP 10 min &#40;mmHg&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0482"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">104&#46;5&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0483"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">17&#46;3&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0484"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">104&#46;1&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0485"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">15&#46;4&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0486"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">0&#46;8&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><a name="en0487"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">SBP 30 min &#40;mmHg&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0488"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">99&#46;4&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0489"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">20&#46;5&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0490"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">98&#46;5&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0491"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">16&#46;6&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0492"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">0&#46;6&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><a name="en0493"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">DBP before &#40;mmHg&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0494"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">57&#46;1&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0495"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">14&#46;3&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0496"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">59&#46;5&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0497"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">9&#46;6&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0498"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">0&#46;4&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><a name="en0499"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">DBP 10 min &#40;mmHg&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0500"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">57&#46;6&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0501"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">12&#46;5&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0502"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">53&#46;7&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0503"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">10&#46;2&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0504"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">0&#46;7&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><a name="en0505"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">DBP 30 min &#40;mmHg&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0506"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">55&#46;4&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0507"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">13&#46;5&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0508"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">52&#46;9&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0509"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">11&#46;5&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0510"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">0&#46;7&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><a name="en0511"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">ABP before &#40;mmHg&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0512"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">71&#46;5&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0513"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">14&#46;3&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0514"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">75&#46;5&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0515"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">10&#46;1&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0516"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">0&#46;3&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><a name="en0517"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">ABP 10 min &#40;mmHg&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0518"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">74&#46;4&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0519"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">13&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0520"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">71&#46;6&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0521"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">12&#46;6&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0522"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">0&#46;6&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><a name="en0523"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">ABP 30 min &#40;mmHg&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0524"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">71&#46;2&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0525"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">13&#46;9&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0526"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">68&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0527"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">12&#46;2&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><a name="en0528"></a><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="top">0&#46;3&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr></tbody></table>
                  """
              ]
              "imagenFichero" => array:1 [
                0 => "xTab3692112.png"
              ]
            ]
          ]
        ]
        "descripcion" => array:1 [
          "en" => "<p id="spara017" class="elsevierStyleSimplePara elsevierViewall">Description of vital signs according to groups and moments and results of statistical tests&#46;</p>"
        ]
      ]
    ]
    "bibliografia" => array:2 [
      "titulo" => "References"
      "seccion" => array:1 [
        0 => array:2 [
          "identificador" => "cebibsec1"
          "bibliografiaReferencia" => array:40 [
            0 => array:3 [
              "identificador" => "bib0001"
              "etiqueta" => "1"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Radiologia de t&#243;rax para pediatras&#44; cl&#237;nica de t&#243;rax para radiologistas"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "JPB Lotufo"
                            1 => "HM&#46; Lederman"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:3 [
                        "tituloSerie" => "S&#227;o Paulo"
                        "fecha" => "2009"
                        "paginaInicial" => "22"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            1 => array:3 [
              "identificador" => "bib0002"
              "etiqueta" => "2"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Atelectasia pulmonar em rec&#233;m-nascidos com doen&#231;as clinicamente trat&#225;veis submetidos &#224; ventila&#231;&#227;o mec&#226;nica&#58; aspectos cl&#237;nicos e radiol&#243;gicos"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "MC Dominguez"
                            1 => "BR&#46; Alvares"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Radiol Bras"
                        "fecha" => "2018"
                        "volumen" => "51"
                        "numero" => "1"
                        "paginaInicial" => "20"
                        "paginaFinal" => "25"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            2 => array:3 [
              "identificador" => "bib0003"
              "etiqueta" => "3"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Atelectasis&#58; mechanisms&#44; diagnosis and management"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "DG Peroni"
                            1 => "AL&#46; Boner"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Paediatric Respiratory Reviews"
                        "fecha" => "2000"
                        "volumen" => "1"
                        "numero" => "3"
                        "paginaInicial" => "274"
                        "paginaFinal" => "278"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            3 => array:3 [
              "identificador" => "bib0004"
              "etiqueta" => "4"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Complications during mechanical ventilation &#8210; A pediatric intensive care perspective"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:4 [
                            0 => "S Sood"
                            1 => "HA Ganatra"
                            2 => "F Perez Marques"
                            3 => "TR Langner"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:3 [
                        "tituloSerie" => "Front Med &#40;Lausanne&#41;"
                        "fecha" => "2023"
                        "volumen" => "10"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            4 => array:3 [
              "identificador" => "bib0005"
              "etiqueta" => "5"
              "referencia" => array:1 [
                0 => array:1 [
                  "referenciaCompleta" => "GHO&#124;By category &#124; Number of deaths by region &#8210; Acute lower respiratory infections &#91;Internet&#93;&#46; WHO&#46; &#91;Acesso em 08 Set 2023&#93;&#46; Dispon&#237;vel em&#58; <a target="_blank" href="https://apps.who.int/gho/data/view.main.CM1002015REG6-CH9?lang=en">https&#58;&#47;&#47;apps&#46;who&#46;int&#47;gho&#47;data&#47;view&#46;main&#46;CM1002015REG6-CH9&#63;lang&#61;en</a>&#46;"
                ]
              ]
            ]
            5 => array:3 [
              "identificador" => "bib0006"
              "etiqueta" => "6"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "What is the role of the physiotherapist in paediatric intensive care units&#63; A systematic review of the evidence for respiratory and rehabilitation interventions for mechanically ventilated patients"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "E Hawkins"
                            1 => "A&#46; Jones"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Physiotherapy"
                        "fecha" => "2015"
                        "volumen" => "101"
                        "numero" => "4"
                        "paginaInicial" => "303"
                        "paginaFinal" => "309"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            6 => array:3 [
              "identificador" => "bib0007"
              "etiqueta" => "7"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Bronchoscopy for atelectasis in the ICU&#58; a case report and review of the literature"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "ME Kreider"
                            1 => "DA&#46; Lipson"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Chest"
                        "fecha" => "2003"
                        "volumen" => "124"
                        "numero" => "1"
                        "paginaInicial" => "344"
                        "paginaFinal" => "350"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            7 => array:3 [
              "identificador" => "bib0008"
              "etiqueta" => "8"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Commentary&#58; Treatment of atelectasis&#58; where is the evidence&#63;"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:1 [
                            0 => "MB Schindler"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Crit Care"
                        "fecha" => "2005"
                        "volumen" => "9"
                        "numero" => "4"
                        "paginaInicial" => "341"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            8 => array:3 [
              "identificador" => "bib0009"
              "etiqueta" => "9"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Atelectasias pulmonares em pediatria&#58; mecanismos&#44; m&#233;todos diagn&#243;sticos&#44; preven&#231;&#227;o e tratamento"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "C Johnston"
                            1 => "P Camassuti"
                            2 => "WB Carvalho"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:4 [
                        "tituloSerie" => "Piva JP&#44; Carvalho WB&#46; PROTIPED"
                        "fecha" => "2023"
                        "paginaInicial" => "11"
                        "paginaFinal" => "62"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            9 => array:3 [
              "identificador" => "bib0010"
              "etiqueta" => "10"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Lobar atelectasis&#58; diagnostics pitfalls on chest radiography"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:4 [
                            0 => "K Ashizawa"
                            1 => "K Hayashi"
                            2 => "N Aso"
                            3 => "K Minami"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Br J Radiol"
                        "fecha" => "2001"
                        "volumen" => "74"
                        "numero" => "877"
                        "paginaInicial" => "89"
                        "paginaFinal" => "97"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            10 => array:3 [
              "identificador" => "bib0011"
              "etiqueta" => "11"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Variability and accuracy in interpretation of consolidation on chest radiography for diagnosing pneumonia in children under 5 years of age"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "GJ Williams"
                            1 => "P Macaskill"
                            2 => "M Kerr"
                            3 => "DA Fitzgerald"
                            4 => "D Isaacs"
                            5 => "M Codarini"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Pediatr Pulmonol"
                        "fecha" => "2013"
                        "volumen" => "48"
                        "numero" => "12"
                        "paginaInicial" => "1195"
                        "paginaFinal" => "1200"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            11 => array:3 [
              "identificador" => "bib0012"
              "etiqueta" => "12"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Fifteen-minute consultation&#58; Using point of care ultrasound to assess children with respiratory failure"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "HL Ord"
                            1 => "MJ&#46; Griksaitis"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Arch Dis Child Educ Pract Ed"
                        "fecha" => "2018"
                        "volumen" => "104"
                        "numero" => "1"
                        "paginaInicial" => "2"
                        "paginaFinal" => "10"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            12 => array:3 [
              "identificador" => "bib0013"
              "etiqueta" => "13"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Right middle lobe atelectasis in children with asthma and prognostic factors"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:5 [
                            0 => "O Soyer"
                            1 => "C Ozen"
                            2 => "O Cavkaytar"
                            3 => "C Seny&#252;cel"
                            4 => "Y&#46; Dallar"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Allergol Int"
                        "fecha" => "2016"
                        "volumen" => "65"
                        "numero" => "3"
                        "paginaInicial" => "253"
                        "paginaFinal" => "258"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            13 => array:3 [
              "identificador" => "bib0014"
              "etiqueta" => "14"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Bedside management of lung collapse in children on mechanical ventilation&#58; Saline lavage &#8210; simulated cough technique proves simple&#44; effective"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "AG Galvis"
                            1 => "G Reyes"
                            2 => "WB&#46; Nelson"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Pediatr Pulmonol"
                        "fecha" => "1994"
                        "volumen" => "17"
                        "numero" => "5"
                        "paginaInicial" => "326"
                        "paginaFinal" => "330"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            14 => array:3 [
              "identificador" => "bib0015"
              "etiqueta" => "15"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Medical treatment of lung collapse in children"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "N Bilan"
                            1 => "BA Galehgolab"
                            2 => "M&#46; Shoaran"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Pak J Biol Sci"
                        "fecha" => "2009"
                        "volumen" => "12"
                        "numero" => "5"
                        "paginaInicial" => "467"
                        "paginaFinal" => "469"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            15 => array:3 [
              "identificador" => "bib0016"
              "etiqueta" => "16"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Children with pulmonary atelectasis&#58; clinical outcome and characterization of physical therapy"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "CCD Pozzo"
                            1 => "PA Seibert"
                            2 => "DS&#46; Fujisawa"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Acta Sci Health Sci"
                        "fecha" => "2013"
                        "volumen" => "35"
                        "numero" => "2"
                        "paginaInicial" => "169"
                        "paginaFinal" => "173"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            16 => array:3 [
              "identificador" => "bib40"
              "etiqueta" => "17"
              "referencia" => array:1 [
                0 => array:1 [
                  "referenciaCompleta" => "Herrada AJM&#44; Wien MA&#44; Shein SL&#44; Maher JK&#44; Zee-Cheng JE&#44; Rotta AT&#46; A novel maneuver to treat refractory atelectasis in mechanically ventilated children&#44; J Pediatr Intensive Care&#44; 2020&#44;11&#40;2&#41;&#44;159-167&#46;"
                ]
              ]
            ]
            17 => array:3 [
              "identificador" => "bib0017"
              "etiqueta" => "18"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Lobar collapse demystified&#58; the chest radiograph with CT correlation"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:4 [
                            0 => "R Mullett"
                            1 => "A Jain"
                            2 => "S Kotugodella"
                            3 => "J&#46; Curtis"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Postgrad Med J"
                        "fecha" => "2012"
                        "volumen" => "88"
                        "numero" => "1040"
                        "paginaInicial" => "335"
                        "paginaFinal" => "347"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            18 => array:3 [
              "identificador" => "bib0018"
              "etiqueta" => "19"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "The use of dornase alpha for post-operative pulmonary atelectasis after congenital heart surgery"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:6 [
                            0 => "E Ozturk"
                            1 => "IC Tanidir"
                            2 => "S Haydin"
                            3 => "IS Onan"
                            4 => "E Odemis"
                            5 => "I&#46; Bakir"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Cardiol Young"
                        "fecha" => "2014"
                        "volumen" => "24"
                        "numero" => "5"
                        "paginaInicial" => "807"
                        "paginaFinal" => "812"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            19 => array:3 [
              "identificador" => "bib0019"
              "etiqueta" => "20"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Lung ultrasound for diagnosis of neonatal atelectasis"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "J Liu"
                            1 => "Y Liu"
                            2 => "H Wang"
                            3 => "J Li"
                            4 => "T Han"
                            5 => "J Liang"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Zhonghua Er Ke Za Zhi &#61; Chinese J Pedia"
                        "fecha" => "2013"
                        "volumen" => "51"
                        "numero" => "9"
                        "paginaInicial" => "644"
                        "paginaFinal" => "648"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            20 => array:3 [
              "identificador" => "bib0020"
              "etiqueta" => "21"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Lung ultrasonography for the diagnosis of neonatal lung disease"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:1 [
                            0 => "J&#46; Liu"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "J Matern Fetal Neonatal Med"
                        "fecha" => "2014"
                        "volumen" => "27"
                        "numero" => "8"
                        "paginaInicial" => "856"
                        "paginaFinal" => "861"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            21 => array:3 [
              "identificador" => "bib0021"
              "etiqueta" => "22"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "International evidence-based recommendations for point-of-care lung ultrasound"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "G Volpicelli"
                            1 => "M Elbarbary"
                            2 => "M Blaivas"
                            3 => "DA Lichtenstein"
                            4 => "G Mathis"
                            5 => "AW Kirkpatrick"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Intensive Care Med"
                        "fecha" => "2012"
                        "volumen" => "38"
                        "numero" => "4"
                        "paginaInicial" => "577"
                        "paginaFinal" => "591"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            22 => array:3 [
              "identificador" => "bib0022"
              "etiqueta" => "23"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Aplicaciones cl&#237;nicas de la ecograf&#237;a pulmonar"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:1 [
                            0 => "AL&#46; Wang&#252;emert P&#233;rez"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Med Clin"
                        "fecha" => "2020"
                        "volumen" => "154"
                        "numero" => "7"
                        "paginaInicial" => "260"
                        "paginaFinal" => "268"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            23 => array:3 [
              "identificador" => "bib0023"
              "etiqueta" => "24"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Lung ultrasonography score to evaluate oxygenation and surfactant need in neonates treated with continuous positive airway pressure"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:6 [
                            0 => "R Brat"
                            1 => "N Yousef"
                            2 => "R Klifa"
                            3 => "S Reynaud"
                            4 => "AS Shankar"
                            5 => "D&#46; De Luca"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:4 [
                        "tituloSerie" => "JAMA Pediatr"
                        "fecha" => "2015"
                        "volumen" => "169"
                        "numero" => "8"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            24 => array:3 [
              "identificador" => "bib0024"
              "etiqueta" => "25"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "A clinical scoring system for the diagnosis of respiratory failure"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:1 [
                            0 => "DW&#46; Wood"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Am J Dis Child"
                        "fecha" => "1972"
                        "volumen" => "123"
                        "numero" => "3"
                        "paginaInicial" => "227"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            25 => array:3 [
              "identificador" => "bib0025"
              "etiqueta" => "26"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Terapia Intensiva Pedi&#225;trica e Neonatal&#46;4<span class="elsevierStyleSup">a</span> Edi&#231;&#227;o"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "MR Hirschheimer"
                            1 => "WB Carvalho"
                            2 => "T&#46; Matsumoto"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Libro" => array:3 [
                        "fecha" => "2017"
                        "editorial" => "Editora Atheneu"
                        "editorialLocalizacion" => "S&#227;o Paulo"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            26 => array:3 [
              "identificador" => "bib0026"
              "etiqueta" => "27"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Micro- and macrorheology of mucus"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:4 [
                            0 => "SK Lai"
                            1 => "YY Wang"
                            2 => "D Wirtz"
                            3 => "J Hanes"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Adv Drug Deliv Rev"
                        "fecha" => "2009"
                        "volumen" => "61"
                        "paginaInicial" => "86"
                        "paginaFinal" => "100"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            27 => array:3 [
              "identificador" => "bib0027"
              "etiqueta" => "28"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Airway clearance therapy in acute paediatric respiratory illness&#58; a state-of-the-art review"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:1 [
                            0 => "BM&#46; Morrow"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "S Afr J Physiother"
                        "fecha" => "2019"
                        "volumen" => "75"
                        "numero" => "1"
                        "paginaInicial" => "1295"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            28 => array:3 [
              "identificador" => "bib0028"
              "etiqueta" => "29"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "I Recomenda&#231;&#227;o brasileira de fisioterapia respirat&#243;ria em unidade de terapia intensiva pedi&#225;trica e neonatal"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:6 [
                            0 => "C Johnston"
                            1 => "NM Zanetti"
                            2 => "T Comaru"
                            3 => "SNS Ribeiro"
                            4 => "LB Andrade"
                            5 => "SLL&#46; Santos"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Rev Bras Terapia Intensiva"
                        "fecha" => "2012"
                        "volumen" => "24"
                        "numero" => "2"
                        "paginaInicial" => "119"
                        "paginaFinal" => "129"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            29 => array:3 [
              "identificador" => "bib0029"
              "etiqueta" => "30"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Immediate effects of respiratory muscle stretching on chest wall kinematics and electromyography in COPD patients"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:6 [
                            0 => "RB S&#225;"
                            1 => "MF Pessoa"
                            2 => "AGL Cavalcanti"
                            3 => "SL Campos"
                            4 => "C Amorim"
                            5 => "AA&#46; Dornelas"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Respir Physiol Neurobiol"
                        "fecha" => "2017"
                        "volumen" => "242"
                        "paginaInicial" => "1"
                        "paginaFinal" => "7"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            30 => array:3 [
              "identificador" => "bib0030"
              "etiqueta" => "31"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Calculating and reporting effect sizes to facilitate cumulative science&#58; a practical primer for t-tests and ANOVAs"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:1 [
                            0 => "D&#46; Lakens"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:4 [
                        "tituloSerie" => "Front Psychol"
                        "fecha" => "2013"
                        "volumen" => "4"
                        "paginaInicial" => "863"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            31 => array:3 [
              "identificador" => "bib0031"
              "etiqueta" => "32"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Atelectasis in pediatrics&#58; mechanisms&#44; diagnosis and treatment"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "C Johnston"
                            1 => "WB&#46; Carvalho"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Rev Assoc Med Bras"
                        "fecha" => "2008"
                        "volumen" => "54"
                        "numero" => "5"
                        "paginaInicial" => "455"
                        "paginaFinal" => "460"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            32 => array:3 [
              "identificador" => "bib0032"
              "etiqueta" => "33"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Diseases of the trachea&#44; bronchi&#44; and smaller airways"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:1 [
                            0 => "NT&#46; Griscom"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Radiol Clin North Am"
                        "fecha" => "1993"
                        "volumen" => "31"
                        "numero" => "3"
                        "paginaInicial" => "605"
                        "paginaFinal" => "615"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            33 => array:3 [
              "identificador" => "bib0033"
              "etiqueta" => "34"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Benefits and harms of normal saline instillation before endotracheal suctioning in mechanically ventilated adult patients in intensive care units&#58; A systematic literature review and meta-analysis"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "SJ Chang"
                            1 => "E Kim"
                            2 => "YO Kwon"
                            3 => "H Im"
                            4 => "K Park"
                            5 => "J Kim"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:3 [
                        "tituloSerie" => "Intensive Crit Care Nurs"
                        "fecha" => "2023"
                        "volumen" => "78"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            34 => array:3 [
              "identificador" => "bib0034"
              "etiqueta" => "35"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Lung ultrasound as a tool to guide respiratory physiotherapy"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:5 [
                            0 => "R Vieira"
                            1 => "E Segura-Grau"
                            2 => "J Magalh&#227;es"
                            3 => "J Santos"
                            4 => "L Patr&#227;o"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "J Clin Ultrasound"
                        "fecha" => "2020"
                        "volumen" => "48"
                        "numero" => "7"
                        "paginaInicial" => "431"
                        "paginaFinal" => "434"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            35 => array:3 [
              "identificador" => "bib0035"
              "etiqueta" => "36"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Is it a high time for a consensus on quantitative lung ultrasound approach&#63;"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "DG Biasucci"
                            1 => "D Buonsenso"
                            2 => "DL&#46; Grieco"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Minerva Anestesiol"
                        "fecha" => "2022"
                        "volumen" => "88"
                        "numero" => "6"
                        "paginaInicial" => "531"
                        "paginaFinal" => "532"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            36 => array:3 [
              "identificador" => "bib0036"
              "etiqueta" => "37"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "A combined rapid clinical and lung ultrasound score for predicting bronchiolitis severity"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:3 [
                            0 => "A&#46; Camporesi"
                            1 => "R&#46; Morello"
                            2 => "A&#46; Guzzardella"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Intensive Care Med Paediatr Neonatal"
                        "fecha" => "2023"
                        "volumen" => "1"
                        "numero" => "14"
                        "paginaInicial" => "1"
                        "paginaFinal" => "11"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            37 => array:3 [
              "identificador" => "bib0037"
              "etiqueta" => "38"
              "referencia" => array:1 [
                0 => array:1 [
                  "referenciaCompleta" => "Pouxtiaux G&#46; Kin&#233;sith&#233;rapie Respiratorie de L&#39;Enfant&#46; Les t&#233;chniques de soins guid&#233;es par I&#39;auscultation pulmonaire&#46; 2&#170; edi&#231;&#227;o&#46; Belgique&#46; De Boeck Universit&#233;&#59; 2000&#46;"
                ]
              ]
            ]
            38 => array:3 [
              "identificador" => "bib0038"
              "etiqueta" => "39"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Sarcomere number regulation maintained after immobilization in desmin-null mouse skeletal muscle"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "SB Shah"
                            1 => "D Peters"
                            2 => "KA Jordan"
                            3 => "DJ Milner"
                            4 => "J Frid&#233;n"
                            5 => "Y Capetanaki"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "J Exp Biol"
                        "fecha" => "2001"
                        "volumen" => "204"
                        "numero" => "10"
                        "paginaInicial" => "1703"
                        "paginaFinal" => "1710"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            39 => array:3 [
              "identificador" => "bib0039"
              "etiqueta" => "40"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Manual hyperinflation in children"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "DM Lorena"
                            1 => "MCM Frade"
                            2 => "THD&#46; Silva"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Rev Bras Ter Intensiva"
                        "fecha" => "2022"
                        "volumen" => "33"
                        "numero" => "4"
                        "paginaInicial" => "616"
                        "paginaFinal" => "623"
                      ]
                    ]
                  ]
                ]
              ]
            ]
          ]
        ]
      ]
    ]
  ]
  "idiomaDefecto" => "en"
  "url" => "/18075932/000000790000000C/v115_202410170932/S1807593224001716/v115_202410170932/en/main.assets"
  "Apartado" => array:4 [
    "identificador" => "94924"
    "tipo" => "SECCION"
    "en" => array:2 [
      "titulo" => "Original articles"
      "idiomaDefecto" => true
    ]
    "idiomaDefecto" => "en"
  ]
  "PDF" => "https://static.elsevier.es/multimedia/18075932/000000790000000C/v115_202410170932/S1807593224001716/v115_202410170932/en/main.pdf?idApp=UINPBA00004N&text.app=https://www.elsevier.es/"
  "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1807593224001716?idApp=UINPBA00004N"
]

Article information

ISSN: 18075932
Original language: English

DOI:10.1016/j.clinsp.2024.100494

The statistics are updated each day

Year/Month	Html	Pdf	Total

2024 October	75	57	132
2024 September	47	48	95

Indexed in:

Follow us:

Statistics

Indexed in:

Follow us:

Statistics

Subscribe to our newsletter