Letter to the Editor
Letter to the Editor
Carta al Editor
Oscar L. Mosquera-Dussána, Daniel Botero-Rosasb,
, Henry Oliverosb
Corresponding author
danybotero@hotmail.com
Corresponding author at: School of Medicine, La Sabana University, Chía-Cundinamarca, Colombia.
Corresponding author at: School of Medicine, La Sabana University, Chía-Cundinamarca, Colombia.
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Mosquera-Dussán, Daniel Botero-Rosas, Henry Oliveros" "autores" => array:3 [ 0 => array:3 [ "nombre" => "Oscar L." "apellidos" => "Mosquera-Dussán" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff0005" ] ] ] 1 => array:4 [ "nombre" => "Daniel" "apellidos" => "Botero-Rosas" "email" => array:1 [ 0 => "danybotero@hotmail.com" ] "referencia" => array:2 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">b</span>" "identificador" => "aff0010" ] 1 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">*</span>" "identificador" => "cor0005" ] ] ] 2 => array:3 [ "nombre" => "Henry" "apellidos" => "Oliveros" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">b</span>" "identificador" => "aff0010" ] ] ] ] "afiliaciones" => array:2 [ 0 => array:3 [ "entidad" => "Doctorado en Biociencias, Universidad de La Sabana, Chía-Cundinamarca, Colombia" "etiqueta" => "a" "identificador" => "aff0005" ] 1 => array:3 [ "entidad" => "School of Medicine, Universidad de La Sabana, Chía-Cundinamarca, Colombia" "etiqueta" => "b" "identificador" => "aff0010" ] ] "correspondencia" => array:1 [ 0 => array:3 [ "identificador" => "cor0005" "etiqueta" => "⁎" "correspondencia" => "<span class="elsevierStyleItalic">Corresponding author at</span>: School of Medicine, La Sabana University, Chía-Cundinamarca, Colombia." ] ] ] ] "titulosAlternativos" => array:1 [ "es" => array:1 [ "titulo" => "Carta al Editor" ] ] "textoCompleto" => "<span class="elsevierStyleSections"><p id="par0005" class="elsevierStylePara elsevierViewall">We are pleased to receive Dr. Eric B. Rosero's<a class="elsevierStyleCrossRef" href="#bib0020"><span class="elsevierStyleSup">1</span></a> editorial comments regarding the trial: “<span class="elsevierStyleItalic">Randomized cross-over clinical trial comparing two pharmacokinetic models of propofol using entropy indexes</span>”.<a class="elsevierStyleCrossRef" href="#bib0025"><span class="elsevierStyleSup">2</span></a></p><p id="par0010" class="elsevierStylePara elsevierViewall">One of the drawbacks of monitoring depth of anesthesia is that the records are usually contaminated with physiological and external artifacts; the reconstruction of a biological signal that accurately represents the relevant biological information is not an easy task. However, the Entropy module<a class="elsevierStyleCrossRef" href="#bib0030"><span class="elsevierStyleSup">3</span></a> includes a pre-processing step that minimizes the introduction of noise into the signals recorded.</p><p id="par0015" class="elsevierStylePara elsevierViewall">There are challenges inherent to the design of crossover trials but it is unlikely that the period effect occurred because the length of time of the surgical procedure was limited to maximum two hours. Given the type of procedure, during that time there were no volume exchanges or relevant changes in the physiological variables such as temperature and other hemodynamic conditions. It should be kept in mind that in terms of the carry-over effect, the washout period shall be enough to prevent the drug from having any pharmacodynamic effects and from interfering with the second treatment period.</p><p id="par0020" class="elsevierStylePara elsevierViewall">With regards to the possibility of experiencing intraoperative recall upon the discontinuation of the propofol infusion (constant remifentanil infusion), no intraoperative awareness was reported during the patients’ follow-up.</p><span id="sec0005" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0005">Funding comment</span><p id="par0025" class="elsevierStylePara elsevierViewall">The authors did not receive any sponsorship to produce this article.</p></span><span id="sec0010" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0010">Conflicts of interest</span><p id="par0030" class="elsevierStylePara elsevierViewall">The authors have no conflicts of interest to declare.</p></span></span>" "textoCompletoSecciones" => array:1 [ "secciones" => array:3 [ 0 => array:2 [ "identificador" => "sec0005" "titulo" => "Funding comment" ] 1 => array:2 [ "identificador" => "sec0010" "titulo" => "Conflicts of interest" ] 2 => array:1 [ "titulo" => "References" ] ] ] "pdfFichero" => "main.pdf" "tienePdf" => true "NotaPie" => array:1 [ 0 => array:2 [ "etiqueta" => "☆" "nota" => "<p class="elsevierStyleNotepara" id="npar0005">Please cite this article as: Mosquera-Dussán OL, Botero-Rosas D, Oliveros H. Carta al Editor. Rev Colomb Anestesiol. 2017;45:80.</p>" ] ] "bibliografia" => array:2 [ "titulo" => "References" "seccion" => array:1 [ 0 => array:2 [ "identificador" => "bibs0005" "bibliografiaReferencia" => array:3 [ 0 => array:3 [ "identificador" => "bib0020" "etiqueta" => "1" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "La caracterización de la profundidad de la anestesia durante las infusiones controladas a objetivo: no es un trabajo fácil" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "E.B. Rosero" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Rev Colomb Anestesiol" "fecha" => "2016" "volumen" => "4" "paginaInicial" => "187" "paginaFinal" => "189" ] ] ] ] ] ] 1 => array:3 [ "identificador" => "bib0025" "etiqueta" => "2" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Ensayo clínico cruzado y aleatorizado para comparar 2 modelos farmacocinéticos de propofol usando índices de entropía" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "O. Mosquera-Dussán" 1 => "A. Cárdenas" 2 => "D. Botero-Rosas" 3 => "A. Yepes" 4 => "H. Oliveros" 5 => "R. Henao" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Rev Colomb Anestesiol" "fecha" => "2016" "volumen" => "44" "paginaInicial" => "194" "paginaFinal" => "202" ] ] ] ] ] ] 2 => array:3 [ "identificador" => "bib0030" "etiqueta" => "3" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Description of the Entropy™ algorithm as applied in the Datex-Ohmeda S/5TM Entropy Module" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "H. Viertiö-Oja" 1 => "V. Maja" 2 => "M. Särkelä" 3 => "P. Talja" 4 => "N. Tenkanen" 5 => "H. Tolvanen-Laakso" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Acta Anaesthesiol Scand" "fecha" => "2004" "volumen" => "48" "paginaInicial" => "154" "paginaFinal" => "161" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/14995936" "web" => "Medline" ] ] ] ] ] ] ] ] ] ] ] ] ] "idiomaDefecto" => "en" "url" => "/22562087/0000004500000001/v1_201701060057/S2256208716300712/v1_201701060057/en/main.assets" "Apartado" => array:4 [ "identificador" => "34049" "tipo" => "SECCION" "en" => array:2 [ "titulo" => "Letter to the Editor" "idiomaDefecto" => true ] "idiomaDefecto" => "en" ] "PDF" => "https://static.elsevier.es/multimedia/22562087/0000004500000001/v1_201701060057/S2256208716300712/v1_201701060057/en/main.pdf?idApp=UINPBA00004N&text.app=https://www.elsevier.es/" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2256208716300712?idApp=UINPBA00004N" ]
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