Article information
Abstract
Liver steatosis, also called non-alcoholic fatty liver, is characterized by a pathological fat accumulation in the liver, leading to liver damage in the form of inflammation and fibrosis. These histological features are similar to those in alcoholic hepatitis. Obesity is known to be the most common cause of simple steatosis in the preadolescent and adolescent population with a consequent serious health risk. The aim of this study was to provide an update on the concepts, pathophysiology and clinical management of hepatic steatosis secondary to obesity at an early age.
Keywords:
Non-alcoholic steatohepatitis
Obesity
Adolescence
Clinical management
Resumen
La esteatosis hepática también denominada hígado graso no alcohólico constituye una entidad clínica patológica caracterizada por una acumulación de componente graso a nivel hepático, circunstancia que implicará necesariamente el desarrollo de un deterioro hepático en forma de inflamación y fibrosis, características histológicas éstas similares a las originadas en una hepatitis alcohólica. En la actualidad se sabe que la obesidad constituye la causa más frecuente de esteatosis hepática simple entre la población preadolescente y adolescente con el consiguiente riesgo que ello supone para la salud de nuestra población juvenil. El objetivo de este trabajo es ofrecer una puesta al día de los conceptos, fisiopatología y manejo clínico de una complicación tan grave como es la esteatosis hepática secundaria a estados de obesidad a edades tempranas.
Palabras clave:
Esteatohepatitis no alcohólica
Obesidad
Adolescencia
Manejo clínico
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