Journal Information
Vol. 16. Issue 3.
Pages 127 (March 1998)
Vol. 16. Issue 3.
Pages 127 (March 1998)
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Trombosis de la arteria hepática y la vena porta secundaria a aspergilosis invasiva tras trasplante hepático
Thrombosis of the hepatic artery and portal vein secondary to invasive aspergillosis following liver transplantation
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F. Gavilán, J. Torre-Cisneros, M. Delgado, J. Briceño, C. Herrero, L. Martínez
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La trombosis de los vasos principales hepáticos es una complicación grave y frecuente en el paciente que precisa trasplante de hígado. La mayoría de las veces es causa de retrasplante urgente. Presentamos 2 casos de trombosis vascular hepática secundaria a aspergilosis diseminada. Ambas pacientes presentaban un estado séptico y precisaron someterse a un segundo trasplante, a pesar de lo cual fallecieron a los pocos días. La autopsia demostró, además, aspergilosis diseminada con invasión del sistema venoso portal y la arteria hepática. Se discuten los factores de riesgo asociados a esta infección y los posibles mecanismos patogénicos.
Palabras clave:
Trombosis vascular
Aspergilosis invasiva
Trasplante hepático
Thrombosis of the main hepatic vessels is a severe, frequent complication in patients requiring liver transplantation. It is usually a cause of emergency retransplantation. Two cases of hepatic vascular thrombosis secondary to disseminated aspergillosis are presented. Both patients demonstrated a septic state and required a second transplantation despite which they died within a few days. Necropsy showed disseminated aspergillosis with invasion of the portal venous system and the hepatic artery. The risk factors associated with this infection and the possible pathogenic mechanisms are discussed.
Keywords:
Vascular thrombosis
Invasive aspergillosis
Liver transplantation